Edere Janumet 850 iji weghachi ọkwa glucose ọbara dị nkịtị. Uru nke ọgwụ a bụ ọnụnọ na ngwakọta nke ihe ndị na-egosipụta mmetụta hypoglycemic akpọpụtara.
International Nonproprietary Aha
Metformin + sitagliptin
Edere Janumet 850 iji weghachi ọkwa glucose ọbara dị nkịtị.
ATX
A10BD07
Ha weputara udi ya na ihe mebere ya
Enwere naanị otu ụdị ọgwụ a - mbadamba. Ihe ndị bụ isi bụ: metformin hydrochloride, sitagliptin phosphate monohydrate. Ta nke ogige ndị a dị iche iche. Otu mbadamba 1 nwere ọgwụ metformin - 850 mg, sitagliptin - 50 mg.
E nwere ụdị Yanumet ndị ọzọ. Ha dị iche naanị na usoro nke metformin. Ọnụ ọgụgụ nke ihe a nwere ike ịbụ 500 mg ma ọ bụ 1000 mg. Sitta sitagliptin bụ 50 mg mgbe niile. Nwere ike ịzụta ọgwụ ahụ na nchịkọta ekwentị. Ọnụọgụ ha n'ime igbe kaadi iche: 1, 2, 4, 6, 7 PC.
Enwere otu ụdị nke mkpụrụ ọgwụ Yanumet.
Omume ọgwụ
Ihe mejuputara ihe ndia na Yanumet diri otu ndi jiri hypoglycemic. A na-eji ha emekọ ihe, n'ihi na ejiri mmeju eme ha. Nke pụtara, metformin na-eme ka mmetụta sitaglipin dị n’ahụ na-emekwa nke ọma. Mgbe ị na-eji ọgwụ ndị a n'otu n'otu, nsonaazụ ọgwụgwọ dịtụ njọ. A na-enyekarị ọgwụ ọgwụ jikọtara ya na usoro ọgwụgwọ mgbe usoro ọgwụgwọ metformin gasịrị, mgbe ọ na-enweghị ike ịnweta ọganihu n'ọrịa onye ọrịa.
Ihe ọ bụla n’ime ihe ndị ahụ na-eme ihe dị iche iche, n’ihi na ihe abụọ ahụ mejupụtara ọgwụ dị iche iche. Dịka ọmụmaatụ, metformin bụ onye nnọchi anya klas biguanide. Ọ naghị emetụta mmepụta insulin. Usoro nke metformin sitere na usoro ndị ọzọ. Agbanyeghị, na usoro ọgwụgwọ a nwere, mmụba na uche nke anụ ahụ na mmetụta nke insulin. Nke a bụ n'ihi mbelata nke ogo insulin na-enwere n'efu. Agbanyeghị, ogo insulin na proinsulin na-abawanye.
Metformin nwere nnukwu uru karịa ihe ndị ọzọ nwere mmetụta hypoglycemic. Yabụ, akụrụngwa a na-emetụta metabolism: ọ na-ebelata njikọ nke abụba n'efu, ebe nsị nke abụba esighi ike, na-egbochi mmụba ha. Yabụ, ya na usoro glucose dị ka iwu dị, enwere mbelata nke oke abụba. Nke a na - eme ka ịdị arọ ya sie ike.
Ọrụ ọzọ nke metformin bụ ịkwụsịlata glucose njikọ n'ime imeju. N'otu oge ahụ, mbelata nke ukwu nke nnweta glucose na eriri afọ. Metformin dị iche na analogues (n'ụkpụrụ sulfonylurea) na nke ahụ anaghị akpalite mmepe nke hypoglycemia. Nyere na akụrụngwa a anaghị emetụta njikọ nke insulin, enwere ike ịchọpụta mgbaàmà nke hyperinsulinemia dị ala.
Ihe mejuputara ihe ndia na Yanumet diri otu ndi jiri hypoglycemic. A na-eji ha emekọ ihe, metformin na-eme ka mmetụta sitaglipin na nke ọzọ ka mma.
Isi ihe nke abụọ (sitagliptin) bụ ihe na - egbochi enzyme DPP-4. Mgbe ewerere ya, a na - arụ ọrụ usoro nke incretin synthesis. Nke a bụ homonụ nke na-enyere aka ịchịkwa nchịkwa onwe nke mmepụta glucose. A na-enye nsonaazụ dị mma n'ihi nsonaazụ nke njikọ insulin na ntinye nke pancreas. Agbanyeghị, ike nke mmepụta glucagon na-ebelata. N'ihi mmepe nke usoro a, a maara ihe mgbochi nke glucose njikọ.
Mlọ ọgwụ
Oke ọdịnaya metformin na-eru mgbe nkeji iri abụọ gachara ị takingụ ọgwụ ahụ. Ndị ọgwụ ọgwụ a na-amalite ngwa ngwa. Mgbe awa isii gachara, ọnụọgụ nke metformin ebido belata. Otu njiri mara nke ihe a bụ enweghị ike ejikọta protein protein. A na-ahuta ya site n’ikike iji nwayọ tinye ihe n’arụ imeju, akụrụ, na mgbakwunye na gland calvary. Iwepu ọkara ndụ na-adị iche n'ọtụtụ awa. Ewepu Metformin n'ahụ ahụ na ntinye nke akụrụ.
N'ihe banyere bioavailability, sitagliptin karịrị akụrụngwa a tụlere. Nrụpụta nke oke a bụ 87 na 60%, otu. Sitagliptin adịghị emetụ ya nke ọma. N'okwu a, a na - ewepụ ọgwụ dị ukwuu n from ọgwụ ahụ n otu ahụ ọ banyere n’ime akụkụ akwara nri. Ọkara ndụ nke ihe a toro ogologo ma bụrụ awa iri na abụọ.
Ihe ngosi maka ojiji
Edere ọgwụ a maka ụdị ọrịa shuga mellitus nke II. Yanumet dị irè karịa ọgwụ ndị na-eme nanị otu ihe dabere na metformin ma ọ bụ ihe ndị ọzọ nwere mmetụta inhibitory na njikọ glucose. Maka nke a, a na-eji ya mgbe enweghị ike ịnweta nsonaazụ dị mma na ọgwụgwọ nke ụdị ọrịa shuga II nke mellitus.
Edere Janumet maka ọrịa shuga nke II.
Enwere ike ịkọ Janumet n'oge ọgwụgwọ mgbagwoju anya yana ọgwụ nke sulfonamide otu. A na-eji ngwá ọrụ ahụ megide nri hypocaloric na mmega ahụ na-adịghị mma.
Ihe ngbanwe
Agaghị eji ọgwụ ahụ eme ihe mgbe mmetụta adịghị mma nke otu onye si mejupụtara ya mere. Ihe mgbochi ndi ozo:
- ọnọdụ dị egwu nke onye ọrịa, na-emetụta akụrụ na-adịghị mma: ujo, ọrịa siri ike;
- ọrịa na-esonyere arụ ọrụ ike, hypoxia;
- ụdị m ọrịa shuga mellitus;
- alisụrụma;
- ịba ụba acidity na ọbara (lactic acidosis).
Edere Janumet nri iji rie ya. E kariri ogo sitagliptin kachasị ogologo kwa ụbọchị (100 mg).
Jiri nlezianya
Ndị ọrịa gaferela afọ 80 kwesịrị iji ọgwụ kpachara anya.
Etu esi ewere Janumet 850?
Mbadamba ụrọ ka edobere iji nri. E kariri ogo sitagliptin kachasị ogologo kwa ụbọchị (100 mg). Oge a tụrụ aro ka ị takingụ ọgwụ bụ ugboro 2 n'ụbọchị.
Na-arịa ọrịa shuga
Ikwesiri ịmalite usoro ọgwụgwọ site na obere ntakịrị nke ihe ndị na-arụ ọrụ (sitagliptin, metformin): 50 na 500 mg, n'otu n'otu. Ogologo ntinye ga-agbanwebeghị n'oge dum ọgwụgwọ (ugboro abụọ n'ụbọchị). Ma, dose nke metformin ji nwayọọ nwayọọ na-abawanye. Mgbe 500 mg gasịrị, dọkịta ahụ depụtara 850, mgbe ahụ 1000 mg. Oge a ga-eme ka mmụba nke ọgwụ ga-ekpebi n’otu n’otu, n’ihi na ọ dabere na steeti ahụ, ọnụnọ nke ọrịa ndị ọzọ.
Mmetụta ọghọm nke Yanumet 850
Mgbaàmà nke sistem: ụjọ ụra, isi ọwụwa, ọgbụgbọ.
Site na usoro akwara: mgbu azụ, mgbu akwara.
Ikwesiri ịmalite usoro ọgwụgwọ site na obere ntakịrị nke ihe ndị na-arụ ọrụ (sitagliptin, metformin): 50 na 500 mg, n'otu n'otu. Mgbe 500 mg gasịrị, dọkịta ahụ depụtara 850, mgbe ahụ 1000 mg.
Ọkpụkpụ afọ
Ogbugbu, afọ dị nro, stools (enwere ike ịgbanyụ ya na nsị ọnya siri ike). Ihe dịkarịsịrị nta bụ ọdịdị nke vomiting.
Site n'akụkụ nke metabolism
Ọrịa Anorexia.
N’oge na-adịghị anya - mbelata nke glycemia, nke a enweghị ihe jikọrọ ya na ngwakọta nke ihe ndị na-arụ ọrụ bụ akụkụ nke Yanumet. N'oge ọnwụnwa nke ụlọ ọgwụ, a chọpụtara na mbelata nke glycemia na-akpata site na mmeghachi omume anụ ahụ na ihe dị iche iche dị n'ime na mpụga na-ejikọtaghị ọgwụ ahụ.
Ọrịa hypoglycemia na ndị ọrịa na-a thisụ ọgwụ a bụ otu ihe ahụ n'ebe ndị ọrịa si n'otu ebe e kenyere metformin na placebo.
Na anụahụ
Rash, itching, ọria, vasculitis, Stevens-Johnson syndrome.
Site na usoro akwara obi
Ahụghị.
Ahụhụ
Urticaria, ya na itching, ihe na-egbu ya, na ya.
Mmetụta ikike ịchịkwa usoro
Enweghị ọmụmụ ihe dị otú ahụ eduzila. Agbanyeghị, ekwesịrị iburu n'uche na ọgwụ ahụ na-akpalite mmepe nke ọtụtụ nsogbu nke usoro ụjọ ahụ (ụjọ ụra, dizziness, wdg). Ya mere, a ga-akpachara anya mgbe ị na-anya ụgbọala.
Ntụziaka pụrụ iche
Enwere ozi gbasara mmekọrịta dị n'etiti ị theụ ọgwụ na mmepe nke ọrịa ọgwụ. Mgbe akara ngosipụta gosipụtara, a na-akwụsị ịgwọ ya na Yanumet.
N'oge usoro ọgwụgwọ a, otu ugboro n'afọ, a na-enyocha ndị na-egosi akụrụ. Site na mbelata dị ukwuu na njikwa nke creatinine, a kagbuola ọgwụ ahụ.
Ọ bụrụ na ejiri Yanumet na-eji insulin eme ihe n'otu oge ma ọ bụ iji otu esi eme ka usoro sulfonylurea, usoro nke ikpeazụ na-edozi (ala).
Enwere ozi gbasara mmekọrịta dị n'etiti ị theụ ọgwụ na mmepe nke ọrịa ọgwụ. Mgbe akara ngosipụta gosipụtara, a na-akwụsị ịgwọ ya na Yanumet.
Site na iji ogwu eji ọgwụ ọgwụ sitagliptin mee ihe, ohere nke ịba ọcha n'anya na-abawanye. Ọzọkwa, ngosipụta na-adịghị mma anaghị apụta ozugbo, mana mgbe ọnwa ole na ole gasịrị.
Jiri n'oge ime na lactation
Mgbe ị na-ebu nwata, enwere ike iji Yanumet, mana ọgwụ a ka edebere na ọ bụrụ na nsonaazụ ọma ya na oke siri ike karịa mmerụ ahụ enwere ike.
N'oge a na-agba ara, a naghị a drugụ ọgwụ ahụ nọ na ajụjụ.
Nhọpụta nke Yanumet ruo ụmụ 850
Edeghị ọgwụ a.
Jiri na agadi
A naghị atụ aro ka iji ọgwụ ọrịa Janumet mee agadi karịa afọ 80. Ewezụga bụ mgbe ịta nke creatinine n'ime ndị agadi nọ n'ogo adịghị mma.
A naghị atụ aro ka iji ọgwụ ọrịa Janumet mee agadi karịa afọ 80.
Ngwa maka ọrụ ezughi oke ọrụ
Site na mmerụ ahụ na-adịghị ike, na-agafeghị oke ma dị oke njọ, a gaghị atụ aro Janumet ka o buru, n'ihi na n'ọnọdụ ọ bụla, itinye uche ya na ahụ na-abawanye.
Jiri maka ọrụ imeju na-arụ ọrụ
Onweghi ozi banyere ebumnuche ọgwụ a nwere ajụjụ gbasara oke ọrụ gbasara akụrụngwa. Maka nke a, ị ga - ezere ị theụ ọgwụ ahụ ma ọ bụrụ na ezughi oke nke ọrụ nke akụkụ a.
Nchịkọta nke Janumet 850
Enweghị ozi gbasara mmepe nke nsogbu ebe ị na-a thisụ ọgwụ a. Ka osila dị, ị metụ ọgwụ metformin karịrị akarị na-eso akpata ọdịda nke lactic acidosis. Isi ihe eji agwọ ọrịa bụ ịba ọcha n'anya. N'ihi nke a, ntinye nke metformin n’ime ọbara ọbara na-ebelata.
Mmekọrịta na ọgwụ ndị ọzọ
A marala ọtụtụ ndị ọrụ na ihe dị iche iche arụmọrụ ha na-agbadata n'okpuru enyemaka nke Yanumet:
- diureta;
- ọgwụ glucocorticosteroid;
- phenothiazines;
- homonụ thyroid;
- phenytoin;
- nicotinic acid.
Gwakọta Janumet na mmanya nwere mmanya ekwesịghị ịdị. Mmanya na-eme ka mmetụta nke metformin nwee usoro metabolic metụtara mgbanwe nke lactic acid.
Na, na Kama nke ahụ, na iji insulin emeghari ọnụ, NSAIDs, MAO inhibitors na ACE inhibitors, ndị ọrụ hypoglycemic, mmụba nke ike nke mmetụta Janumet na ahụ.
Remata nke furosemide bụ ihe kpatara mmụba okpukpu abụọ na mkpokọta nke ihe ndị dị mkpa nke ndị ọrụ ahụ metụtara.
Ọrụ Digoxin na-abawanye n'oge ọgwụgwọ ya na Yanumet.
Sitta ahụ sitagliptin na-abawanye mgbe ị na-ewere Cyclosporin na Yanuvia.
Mmanya ndakọrịta
Gwakọta Janumet na mmanya nwere mmanya ekwesịghị ịdị. Mmanya na-eme ka mmetụta nke metformin nwee usoro metabolic metụtara mgbanwe nke lactic acid.
Analogs
Enwere ọtụtụ ọnya nnọchi dị iche na usoro ha si arụ ọrụ na ihe mejupụtara. Mgbe ị na-ahọrọ, mmadụ kwesịrị iburu n'uche ogo nke oke ike nke mmetụta ha nwere n'ahụ ahụ, yana ụdị ntọhapụ. O kwere omume analogues:
- Gluconorm;
- Ndị Glucovans;
- Glibomet;
- Galvus Met et al.
Nke mbu n'ime ihe abuo bu ihe eji eme ihe abuo, ma o nwere metformin na glibenclamide. Nke abụọ n'ime ihe ndị ahụ na-ezo aka na usoro sulfonylurea, nke pụtara na site na ọgwụ a, ihe ize ndụ nke mmetụta ndị ọzọ na-abawanye. Gluconorm dị iche na Yanumet n'echiche na-enweghị ike iji ya mee n'oge afọ ime na lact. Ọnụahịa ọgwụ a dị ala (250 rubles).
Glucovans bụ analog nke Gluconorm. Ngwakọta ahụ nwekwara metformin na glibenclamide. Enwere ike iji ọgwụ ahụ dochie Janumet, ma ọ bụrụ na enweghi contraindications. Agbanyeghị, ekwesighi iji ya kama Gluconorm.
Glibomet nwere metformin na glibenclamide. Ntinye uche nke ihe aru oru di iche iche nwere ike idi obere, na-abawanye ma obu iwetulata ihe uto nke ogwu na aru, nke ekwesiri iburu n'uche, ebe obuna mgbanwe mgbanwe n’usoro nke ị ofụ ọgwụ hypoglycemic nwere ike ibute mmepe nke nsogbu.
Galvus Met dị iche na nhazi. O nwere metformin na vildagliptin. Dika odi na mbu, uzo metformin kariri ego nke ihe abuo nke abuo. Enweghị ike iji ọgwụ ahụ n'oge ime na lactation. Agbanyeghị, enwere ike iji ya na insulin, ọgwụ sitere na otu sitere na usoro nke sulfonylurea.
Galvus Met nwere metformin na vildagliptin, enwere ike iji ya na insulin, ego sitere na otu nke usoro nke sulfonylurea.
Ahịa ọgwụ na-ahapụ okwu
Ogwu bu ogwu.
Enwere m ike ịzụta na ndenye ọgwụ?
Onweghi udiri ya, ikari ido dọkịta di nkpa.
Ọnụ ego maka Janumet 850
You nwere ike ịzụta ngwaahịa a na ọnụahịa nke 2800 rubles.
Ọnọdụ nchekwa maka ọgwụ
A na-atụ aro ya iji dozie ọnụ ụlọ ahụ n'ime + 25 Celsius С.
Bọchị mmebi
Nkwadebe nwere 850 na 50 mg nke bekee na-ejigide ihe ala dị mkpirikpi karịa ka analog nke 500 na 50 mg. Ndụ nchekwa nke ngwaahịa a na-ajụ bụ afọ 2.
Emeputa
Companylọ ọrụ "Pateon Puerto Rico Inc." na USA.
Nyocha banyere Yanumet 850
Valeria, onye gbara afọ 42, Norilsk
Achọpụtara m ọrịa ahụ ogologo oge gara aga, ebe ọ bụ na mgbe ahụ, m na-ewerekarị ọgwụ hypoglycemic. N’oge iwe, ọgwụ ndị mejupụtara ọgwụ na-enyere aka adịghị ike. N'oge ndị dị otú a, dọkịta ahụ tụrụ aro ka ọ were Janumet. Ọ na-enyere ọ fọrọ nke nta ka ọ bụrụ ozugbo, mana ọrụ ya na-ebelata ngwa ngwa. Na mgbakwunye, ọnụ ahịa ọgwụ ahụ dị elu.
Anna, 39 dị afọ 39, Bryansk
Ngwá ọrụ dị irè, ana m edebe ya n'ụlọ na kabinet ọgwụ. Enwere m mmasị na mmetụta ya na ụwa niile: na-egbochi ịdị arọ ya, ọkwa glycemia na-agbanwe, insulin insulin adịghị etinye ya. Ekwere m na iji ya bụ naanị mgbakwunye, ma ọ bụrụ na ị mebie usoro ọgwụgwọ ahụ.
