Contraindications, nsonaazụ na ntinye dị mkpa maka iji Fraxiparin

Nsogbu banyere coagulation ọbara, nsị thromboembolic bụ nnukwu ọrịa nke chọrọ ọgwụgwọ ozugbo.

Ọtụtụ mgbe n'ọnọdụ ndị dị otú ahụ, ndị dọkịta depụtara ọgwụ Fraxiparin. A na - achọta nsonaazụ na contraindications maka iji ya, ọ dịkwa mkpa ịmara banyere ha.

A ga-atụle nsogbu ndị a, yana ozi banyere iji ọgwụ ahụ, nsonaazụ ya na nyocha ga-emecha.

Omume ọgwụ

Fraxiparin nwere heparin dị ala nke nwere obere ihe, ihe okike nke arụpụtara na usoro iji depolymerization. Otu ihe e ji mara ọgwụ ahụ ka a na-akpọ ọrụ ya n'ihe gbasara coagulation factor Xa yana yana adịghị ike nke ihe Pa.

A na-ekwupụta ọrụ Anti-Xa karịa karịa ihe onye ọrụ ahụ na-arụ na oge akụkụ mkpụrụ akụkụ thrombotic. Nke a na-egosi ọrụ antithrombotic.

Ọgwụ a nwere ọgwụ mgbochi mkpali na mmetụta immunosuppressive. Ọzọkwa, a ga-ahụta ihe onye ahụ na - eme ngwa ngwa ngwa ngwa, ọ na - anọ ogologo oge. N'ime awa 3-4, a na-etinye ọgwụ ahụ kpamkpam. A na - ekeji ya na mmamịrị n’akụrụ akụrụ.

Ihe ngosi maka ojiji

Usoro nke Fraxiparin maka usoro ndị a:

• ọgwụgwọ nke infarction myocardial;
• igbochi nsogbu nke thromboembolic, dịka ọmụmaatụ, mgbe ọwachara ahụ, ma ọ bụ na-enweghị ịwa ahụ;
• profalaxis nke coagulation n'oge ịba ọcha n'anya;
• ọgwụgwọ nke nsogbu nke thromboembolic;
• ọgwụgwọ nke angina pectoris ejighị n'aka.

Leasedị mwepụta, ihe mejupụtara

Ntughari nke Fraxiparin di na uzo nke uzo injection, edobere ya na sirinji. Mpekere onwe ya dị na bluse, nke a na-etinye ya na mpempe akwụkwọ 2 ma ọ bụ 10 na igbe kaadi.

Ihe mejupụtara ya nwere ihe arụ ọrụ a na-akpọ calcium adroparin 5700-9500 IU. Ihe inyeaka a bụ: calcium hydroxide, mmiri dị ọcha, na acid chloric.

Nsonaazụ

Dị ka ọtụtụ ọgwụ, Fraxiparin mgbe ụfọdụ na-akpata nsonaazụ:

• thrombocytopenia;
• Mmeghachi omume nfụkasị (na-esikarị na ọrịrị Fraxiparin itchy), gụnyere ụbụrụ Quincke;
• ọbara ọgbụgba nke ọnọdụ dị iche iche;
• akpụkpọ necrosis;
• nnennen;
• eosinophilia mgbe mwepụ ọgwụ ọjọọ;
• hyperkalemia atụgharị;
• guzobe obere hematoma na ntụtụ, mgbe ụfọdụ nnukwu ọnya sitere na Fraxiparin na-apụta (foto dị n'okpuru);
• mmụba na ọdịnaya nke enzyme hepatic.

Patientsfọdụ ndị ọrịa ji Fraxiparin kwuru na ọ na-enwe mmetụta dị oke ọkụ mgbe a gbasịrị ya.

Ihe ngbanwe

Ihe mkpuchi Contraindications Fraxiparin nwere ndị a:

• thrombocytopenia;
• afọ ruo afọ 18;
• ọnya anụ ahụ dị n’ahụ na-enwekarị ọbara ọgbụgba;
• ọbara ọgbụgba n'ime intracranial;
• uche ime ihe na ngafe nke usoro;
• ịwa ahụ ma ọ bụ mmerụ ahụ nke anya, ụbụrụ na ọgidigi azụ;
• ọbara ọgbụgba ma ọ bụ nnukwu ihe ọghọm nke ihe mere na ya mebiri hemostasis;
• odida akwara na-esite na infarction myocardial, angina na-ejighi ike, ọgwụgwọ nke thromboembolism.

N'ịba ụba nke ọbara ọgbụgba, ekwesịrị iji nlezianya kpoo Fraxiparin. Ọnọdụ ndị a bụ ndị a:

• afọ imeju;
• Ọrịa mgbasa na retina na choroid;
• ogologo oge ọgwụgwọ karịa ka ọ tụrụ aro;
• ịdị arọ ya ruo kilogram 40;
• oge ịwa ahụ anya, eriri azụ, ụbụrụ;
• nnukwu ọbara ọgbụgba;
• enweghị nrube isi na ọnọdụ ọgwụgwọ;
• ọnya afọ-ụlo;
• ị medicationsụ ọgwụ n’otu oge ahụ nwere ike inye aka na ọgbụgba ọbara.

Ntụziaka maka ojiji

A na-ewebata Fraxiparin n’ime afọ n’ime akwara dị n’okpuru ala. A ga-edozikwa akpụkpọ anụ ahụ oge niile mgbe a na-edozi otu esi edozi.

Onye ọrịa ahụ gha gha ụgha. Ọ dị mkpa na agịga ahụ dị ntakịrị, ọ bụghị n'akụkụ.

N'ime usoro ịwa ahụ niile maka igbochi nsogbu nke thromboembolic, a na-achịkwa azịza ya na oke 0.3 ml otu ugboro kwa ụbọchị. A na-a drugụ ọgwụ ahụ ọ dịkarịa ala otu izu ruo oge ihe ize ndụ gafere.

A na-enye ọgwụ izizi tupu ịwa ahụ n’ime awa 2-4. N'ihe banyere ịwa ahụ orthopedic, a na-enye ọgwụ ahụ awa iri na abụọ tupu a waa ya arụ yana awa iri na abụọ mgbe ọ gbasịrị. Ọzọkwa, a na-a theụ ọgwụ ahụ ma ọ dịkarịa ala ụbọchị 10 ruo na njedebe nke oge ahụ.

Ọ bụ usoro ọgwụgwọ maka ọgwụ mgbochi ka esiri tụọ ya n'ahụ onye ọrịa:

• 40-55 n'arọ - otu ugboro kwa ụbọchị maka 0,5 ml;
• 60-70 n'arọ - otu ugboro n'ụbọchị maka 0.6 ml;
• 70-80 n'arọ - ugboro abụọ n'ụbọchị, 0.7 ml nke ọ bụla;
• 85-100 n'arọ - ugboro abụọ n'ụbọchị maka 0.8 ml.

Maka ọgwụgwọ nke nsogbu ọgwụ thromboembolic, a na-a drugụ ọgwụ ahụ n’etiti awa 12 ugboro abụọ n’ụbọchị ruo ụbọchị iri.

Na ọgwụgwọ nke nsogbu nke thromboembolic, ịdị arọ mmadụ na-ekere òkè na ịchọpụta dose:

• ihe ruru 50 n'arọ - 0.4 mg;
• 50-59 n'arọ - 0,5 mg;
• 60-69 n'arọ - 0.6 mg;
• 70-79 n'arọ - 0.7 mg;
• 80-89 n'arọ - 0.8 mg;
• 90-99 n'arọ - 0.9 mg.

Na mgbochi nke ịmịnye ọbara ọbara, ekwesịrị ịkụnye dose ahụ iche iche dabere na teknuzu nke ọnọdụ akwara. Dị ka ọ na-adị, mgbe a na-egbochi coagulation, ndo bụ ọgwụ mbụ nke 0.3 mg maka ndị mmadụ ruru 50 n'arọ, 0.4 mg ruo 60 n'arọ, 0.6 mg karịa 70 n'arọ.

A na-atụ aro ọgwụgwọ nke infarction myocardial na angina na-akwụghị chịkọtara yana Aspirin ruo ụbọchị 6. Na mbu, ogwu ya ka abanye n’ime catheter. Ọgwụ eji bụ 86 ME anti-Xa / n'arọ. Na-esote, a na-ahụ maka azịza ya n'okpuru subcutaneously ugboro abụọ n'ụbọchị otu usoro.

Dodoụbiga ya ókè

N'ihe banyere ịdoụ ọgwụ ụdị ọgwụ a, ọbara ọgbụgba nke ọbara dị iche iche na-apụta. Ọ bụrụ na ha enweghị ihe ọ bụla, yabụ echegbula. N'ọnọdụ a, ịkwesịrị belata usoro onunu ogwu, ma ọ bụ iwelie etiti dị n'etiti inje. Ọ bụrụ na ọbara ọgbụgba ahụ dị oke mkpa, mgbe ahụ ịkwesịrị ị proụ protamine sulfate, 0.6 mg nke nwere ike dochie 0.1 mg nke Fraxiparin.

Mkparịta ụka ọgwụ ọjọọ

Fakingụ ọgwụ n'ezoghị ọnụ n'otu oge na ọgwụ ụfọdụ nwere ike ibute hyperkalemia.

Ndị a gụnyere: salts salt, ACE inhibitors, heparins, NSAIDs, potassium-sparing diuretics, Trimethoprim, angiotensin II anti blooror blockers, Tacrolimus, Cyclosporin.

Ọgwụ ndị na-emetụta hemostasis (anticoagulants na-apụtaghị ìhè, acetylsalicylic acid, NSAIDs, fibrinolytics, dextran), yana iji ihe a, na-eme ka ibe ha dịwanye mma.

Ọdịmma ọbara na-abawanye ma ọ bụrụ na ewere Abciximab, Beraprost, Iloprost, Eptifibatide, Tirofiban, Ticlopedin. Acetylsalicylic acid nwekwara ike inye aka na nke a, mana ọ bụ naanị na usoro ọgwụgwọ mgbochi, ya bụ 50-300 mg.

Ekwesịrị iji nlezianya depụta Fraxiparin mgbe ndị ọrịa natara dextrans, anticoagulants na-adịghị mma, na corticosteroids systemic. N'ihe banyere iwere ọgwụ anticoagulants na-apụtaghị ìhè na ọgwụ a, a na-aga n'ihu iji ya ruo mgbe ihe ngosi INR na-ahụkarị.

Nyocha

Dị ka ọ dị n'ọtụtụ ọgwụ ndị ọzọ, enwere nyocha na-emegiderịta banyere Fraxiparin. Enwere ndị o nyeere aka, a na-elekwa ya anya dị ka ndị na-arụ ọrụ, mana ndị ọrịa na-ewere ọgwụ ahụ abaghị uru ọ bụla.

Nyocha ndị na-adịghị mma na-esite na ọnụnọ nke ọnụọgụ mmetụta dị ukwuu, contraindications. N'otu oge, n'agbanyeghị ịdọ aka ná ntị banyere ị takingụ ọgwụ ahụ na ụmụ nwanyị dị ime, enweghị mmetụta ọ bụla na ahụike na mmepe nke nwatakịrị ahụ.

Vidiyo ndị metụtara

Etu esi abanye Fraxiparin:

Ya mere, Fraxiparin na-edekarị ya maka nsogbu nke ọbara ụkọ ọbara, mkpa maka ọgwụgwọ ma ọ bụ igbochi nsogbu nke thromboembolic. Isi ihe bụ ịgbaso ndụmọdụ nke otu ọkachamara nke nwere ike ikpebi nnabata nke ojiji ya na usoro ọgwụgwọ achọrọ. Ma ọ bụghị ya, na mgbakwunye na enweghị mmetụta, na ntụle, enwere ike inwe mmetụta ọjọọ na ị anụbiga mmanya ókè, mmepe nke ọbara ọgbụgba, na hyperkalemia.