A na-eme ọgwụ ọgwụgwọ nke ọrịa shuga site na iji ọgwụ ndị, na-enweghị mmepụta nke homonụ nke onwe ha (insulin), nwere ike belata glycemia dị elu ma gbochie nsogbu nke ọrịa ahụ.
Enwere ike ekewa ọgwụ niile ụzọ abụọ dị iche iche: insulins nke durations dị iche iche nke ọgwụ na tableted. N'ime ụdị ọrịa shuga mbụ, ndị ọrịa chọrọ insulin, ọgwụgwọ nke ndị ọrịa nwere ụdị shuga 2 na-agụnye ntinye ya na usoro njikọta ọnụnọ nke ngosipụta nke mmadụ.
Carme ọgwụ insulin na-emepụtagharị ụzụ sitere n'okike nke imepụta na ntọhapụ nke homonụ site na mkpụrụ ndụ islet nke pancreas, ya mere, ọgwụ dị mkpụmkpụ, ọkara na ogologo.
Kedu ka insulin na protamine si arụ ọrụ?
A na - etinye ihe pụrụ iche a na - akpọ protamine na insulins ndị na - eme ihe dị ala iji belata nnabata nke ọgwụ ahụ na saịtị ahụ. N'ihi protamine, mmalite nke mbelata ọbara shuga na-amalite awa abụọ ma ọ bụ anọ mgbe nchịkwa gasịrị.
Mmetụta kachasị na-apụta mgbe awa 4-9 gachara, oge ahụ dum sitere na elekere 10 ruo 16. Zọ puru iche nke ntopute nke mmetụta hypoglycemic na-eme ka o kwe omume maka insulins ndị dị otú a iji dochie ọrụ nke ihe nzuzo nkịtị.
Protamine na - akpata klọọkụ insulin n'ụdị flakes, yabụ na ọdịdị nke insulin proulin bụ igwe ojii, nkwadebe niile nke insulins dị mkpirikpi na-apụta. Ihe mejupụtara ọgwụ ahụ gụnyere zinc chloride, sodium phosphate, phenol (ihe nchekwa) na glycerin. Otu mililita nke nkwụsị nke protamine-zinc-insulin nwere 40 PIECES nke homonụ.
Nkwadebe insulin nke proulinine nke RUE Belmedpreparaty nwere aha azụmahịa Protamine-Insulin ChS. Uzo a gosiputara uzo esi eme ogwu a.
- Mkpakọrịta na onye na-anabata ya na akpụkpọ ahụ.
- Guzobe ulo oru nnabata insulin.
- N'ime sel nke imeju, akwara na anụ ahụ adipose, a na - amalite njikọ nke enzymes.
- Mkpụrụ ndụ na-ewere glucose ma na-etinye ya n’ahụ.
- A na-eme ngwa ngwa glucose intracellular.
- A na-akpali nguzobe nke abụba, protein na glycogen.
- N’ime imeju, imepụta ụmụ irighiri glucose ọhụụ na-ebelata.
Ebumnuche ndị a bụ iji wedata ogo glucose dị n'ọbara ma were ya mepụta ike n'ime sel. Ọnụego mmalite na oge ngụkọta nke Protamine insulin ES dabere na usoro enyere, usoro na ebe ịgba.
N'ime otu onye ahụ, paramp ndị a nwere ike ịdị iche na ụbọchị dị iche iche.
Ihe ngosiputa maka ojiji na uzo ogwu nke ogwu
Ekwesiri inye proulinine-zinc-insulin maka ndị ọrịa nwere ụdị ọrịa shuga mbụ na ọrịa shuga, a nwekwara ike ịkwado ya maka ọbara mgbali elu n'ọkwa nke abụọ.
Nke a nwere ike ịbụ na iguzogide mbadamba iji belata shuga ọbara, yana mgbakwunye nke ọrịa na-efe efe ma ọ bụ ọrịa ndị ọzọ na-efe efe, yana n'oge ime. A na-ebugharị ndị ọrịa nwere ụdị ọrịa shuga 2 nke ọrịa insulin ma ọ bụrụ na ọrịa shuga na-eso nnukwu nsogbu ma ọ bụ nkwarụ akwara.
A na-egosi ọgwụ ọgwụ dịka protamine-zinc-insulin ma ọ bụrụ na ịwa ahụ dị mkpa, ma ọ bụrụ na achọpụtara ọrịa shuga na mbụ, ọnụ ọgụgụ glycemia dị elu ma ọ bụ ma ọ bụrụ na enwere ọgwụ ndị dị na mbadamba ahụ.
A na - achịkwa pro protinine-insulin subcutaneously, usoro ya dabere na - egosi hyperglycemia nke mmadụ n'otu n'otu, na-agbakọkwa na nkezi kwa 1 kilogram nke ahụ. Nlekọta kwa ụbọchị sitere na 0,5 ruo 1.
Atụmatụ ọgwụ:
- A na-eji ya naanị subcutaneously. A machibidoro nchịkwa mgbochi nke insulin nke insulin.
- A na-echekwa karama emechiri emechi na friji, ma mgbe ejiri ya ruo ogo 25 ruo izu isii.
- Chekwaa vulul insulin eji mee ya na n ụlọ okpomọkụ (ruo 25 Celsius) maka izu isii.
- Okpomoku nke insulin na mmeghe kwesiri ibu okpomoku ulo.
- N'okpuru mmetụta nke okpomọkụ, ìhè anyanwụ kpọmkwem, kefriza, insulin na-efunari ihe ya.
- Tupu ị wepụta protamine, a ga-agbanye insulin insulin n'ime n'ọbụ aka ruo mgbe ọ dị mma ma nwee urukpuru. Ọ bụrụ na enweghị ike ịme, nke a agaghị enye ọgwụ a.
Enwere ike ịhọrọ mpaghara ịgba ọgwụ ahụ dabere n'ọchịchọ onye ọrịa, mana ekwesịrị iburu n'uche na ọ na-agbadata n'otu n'otu na nwayọ nwayọ site na apata ụkwụ. Ọnọdụ nke abụọ na-atụ aro ya bụ mpaghara ubu (deltoid muscle). Oge ọ bụla ịchọrọ ịhọrọ ebe ọhụrụ n'ime mpaghara mpaghara ahụ iji gbochie mbibi nke anụ ahụ dị n'okpuru.
Ọ bụrụ na enyere onye ọrịa ọgwụ usoro insulin siri ike, mgbe ahụ, a na-eme insulin insulin nke zinc n'ụtụtụ ma ọ bụ na mgbede, na mgbe egosipụtara, ugboro abụọ (n'ụtụtụ na mgbede). Tupu ị rie nri, a na - eji insulin dị mkpụmkpụ.
N'ime ụdị shuga nke abụọ, a na-ahụkarị Protamine-insulin ES na mgbakwunye na ọgwụ glypoglycemic, nke edepụtara maka nchịkwa ọnụ, iji mee ka mmetụta ha ka mma.
Ihe ndi n’egwuregwu insulin
Nsogbu a na-ahụkarị na ọgwụ insulin bụ mbelata ọkwa glucose ọbara n’etiti ọkwa ndị nkịtị. A na-eme ka nke a site na nsogbu na-adịghị mma site na obere carbohydrates na oke insulin, nri nri, nrụgide anụ ahụ, na-agbanwe ebe injection.
A na-ebute hypoglycemia site na ọrịa concomitant, ọkachasị ndị nwere oke ọkụ, afọ ọsịsa, vomiting, yana ịchịkọta ọgwụ nke na-eme ka insulin rụọ ọrụ.
Mmalite mberede nke mgbaàmà hypoglycemia bụ ihe a na-ahụ maka ọgwụgwọ insulin. Ọtụtụ mgbe, ndị ọrịa na-enwe mmetụta nke nchekasị, anya mmiri, ọsụsọ oyi, aka na-ama jijiji, adịghị ike na-enweghị atụ, isi ọwụwa na palpitations.
Akpụkpọ ahụ na-acha odo odo, agụụ na-abawanye n'otu oge ahụ ọgbụgbọ na-eme. Mgbe ahụ nsụhọ na-echegbu ya, onye ọrịa ahụ daba na nsogbu. Ọ bụrụ na ọnụego shuga dị n'ọbara na-emebi ụbụrụ ma ọ bụrụ na a gwọghị ya, ndị ọrịa nọ n'ihe ize ndụ nke ọnwụ.
Ọ bụrụ na onye ọrịa na - arịa ọrịa shuga maara ihe, mgbe ahụ ị nwere ike belata mwakpo ahụ site na iji shuga ma ọ bụ ihe ọ juiceụ sweetụ dị ụtọ, kuki. Site n'ọkwa dị elu nke hypoglycemia, a na-eduzi ntụpọ glucose na glucagon intramuscular. Mgbe imeziwanye ahụike, onye ọrịa ahụ kwesiri iri nri nke ọma na enweghị ọgụ ugboro ugboro.
Dosehọrọ nhọrọ na-ezighi ezi ma ọ bụ nchịkwa agbaghara nwere ike ibute ọgụ hyperglycemia na ndị ọrịa dabere na insulin. Ihe mgbaàmà ya na-abawanye nwayọ, njirimara kachasị bụ ọdịdị ha n'ime awa ole na ole, mgbe ụfọdụ ruo ụbọchị abụọ. Obi mgbawa na-abawanye, ihe mmamịrị mmụba na-abawanye, agụụ na-ebelata.
Mgbe ahụ enwere ọgbụgbọ, ọgbụgbọ, isi nke acetone n'ọnụ. Na enweghị insulin, onye ọrịa ahụ dara ada. Achọrọ nlekọta ahụike mberede maka ọrịa mamịrị na ndị otu ambulance.
Maka nhọrọ ziri ezi nke dose ahụ, ọ dị mkpa iburu n'uche na mgbe ọnọdụ onye ọrịa ma ọ bụ ọrịa na-agbanwe agbanwe gbanwere, a chọrọ nhazi ọgwụgwọ. Egosiputa ya n'ụdị ndị a:
- Ọrịa nke thyroid gland.
- Ọrịa nke imeju ma ọ bụ akụrụ, karịsịa na agadi.
- Ọrịa malitere ịrịa.
- Physicalba ahụ ike.
- Chingtụgharị na nri ọzọ.
- Mgbanwe nke ụdị insulin, onye na-emepụta ihe, mgbanwe site na anụmanụ gaa na mmadụ.
Ojiji inulin na ọgwụ sitere na otu nke thiazolidinediones (Aktos, Avandia) na-ebulite ohere nke nkụda obi. Yabụ, a na-atụ aro ka ndị ọrịa nwere nsogbu obi nwee ike ilele oke nke anụ ahụ anya iji chọpụta edema edere.
Mmeghachi omume nfụkasị ahụ nwere ike ịbụ nke mpaghara n'ụdị ọzịza, ọbara ọbara, ma ọ bụ itching akpụkpọ ahụ. Ha anaghị adịkarị mkpụmkpụ ma na-agafe onwe ha. Ihe ngosi a na-ahụkarị nke ahụ na-akpata ọrịa ndị a: ihe ọkụ ọkụ na ahụ, ọgbụgbọ, angioedema, tachycardia, mkpụmkpụ ume. Mgbe ha mere, a na-eme ọgwụgwọ pụrụ iche.
A machibidoro ọnọdụ mberede insulin ahụ ma ọ bụrụ na mmadụ na-arịa onwe ya na hypoglycemia.
Protinine nke insulin n'oge ime na lactation
Ebe ọ bụ na insulin anaghị agafe Plasenta, n’oge ime ya, enwere ike iji ya kwụọ ụgwọ ọrịa shuga. Mgbe ị na-eme atụmatụ ịtụrụ ime, egosipụtara nyocha zuru oke nke ụmụ nwanyị nwere ọrịa shuga.
Nkeji ato na - ebido na mgbada nke mbelata nke chọrọ insulin, na nke abụọ na nke atọ nwere mmụba nwayọ nwayọ na ọgwụ nchịkwa. mgbe amuchara umu, a na - eme insulin ogwu n’usoro ogwu. N'oge a na-ebuga ya, mbelata nke ukwu nke ọgwụ a na-enye nwere ike ime.
Enwere ike ijikọta mkpuchi na nchịkwa insulin, ebe insulin enweghị ike ịbanye na mmiri ara. Ma mgbanwe na usoro homonụ nke ụmụ nwanyị chọrọ ntụtụ karịa ugboro ole ọkwa glycemia na nhọrọ nke usoro ziri ezi.
Mmekọrịta nke insulin na ọgwụ ndị ọzọ
A na - eme ka ihe insulin dịkwuo mma ma ejiri ya na mbadamba shuga dị ala, ihe mgbochi beta, sulfonamides, tetracycline, lithium, vitamin B6.
Bromocriptine, anabolic steroid. Hypoglycemia nwere ike ime na ngwakọta nke insulin na ketokenazole, clofibrate, mebendazole, cyclophosphamide, na mmanya mmanya.
Ndị ọrịa nwere mmasị n’ajụjụ esi ewelata insulin n’ime ọbara. Nicotine, morphine, clonidine, danazole, mgbochi ụrọ mbadamba, heparin, thiazide diuretics, glucocorticosteroids, tricyclic antidepressants, homonụ thyroid, ọmịiko na ọgwụ ndị na-egbochi ọgwụ nwere ike belata ọrụ insulin.
Vidio dị n’isiokwu a na-agwa mgbe achọrọ insulin na otu esi abanye ya.
