Isi ihe eji eji Krestor bụ ịba ụba nke cholesterol n'ihe banyere hypercholesterolemia, atherosclerosis na ọrịa obi ndị ọzọ.
Mbadamba ihe ndị ọrịa na-anabataghị mbadamba ọfụma, nsonaazụ ya na - adịkarị ụdi. Ọ bụrụ na ọ dị mkpa, ọkachamara ahụ na-edepụta okwu ntụgharị (Rosuvastatin, Rosart, Mertinil) ma ọ bụ analogues (Atoris, Vasilip, Zokor). Enwere ike ịchọta ozi zuru ezu karị na ihe a.
Ozi izugbe ọgwụ
Onye na-emepụta ọgwụ ahụ bụ ụlọ ọrụ ọgwụ AstraZeneca UK Limited, nke dị na UK.
Crestor (aha Latin - Crestor) eweputara ya na mbadamba ihe eji eme ihe. Usoro onunu ogwu nwere ike di iche - 5, 10, 20 ma obu 40 mg nke ihe aru oru. Ihe mkpuchi nke kaadiboodu, nke enwere ike ịhụ na foto dị na ntanetị, nwere blister abụọ nke mbadamba 14.
Otu mbadamba gụnyere rosuvastatin calcium (rosuvastatin) na ndị na-arụ ọrụ. A na-eme mbadamba gburugburu ma ọ bụ oval, agba ha na-adabere na usoro onunu ogwu - odo (5 mg) na pink (10, 20, 40 mg).
Obe nwere ihe osisa. Rosuvastatin, na-abawanye ọnụ ọgụgụ ndị na-anabata umeji, na -ebelata ọdịnaya nke cholesterol "ọjọọ" (LDL na VLDL) n'ime ọbara. N'ihi nke a, dissimilation (catabolism) na usoro nke LDL uptake na-agbadata ngwa ngwa, a na-ebelata mmepụta nke cholesterol “ọjọọ”.
N'ihi ya, otu izu mgbe ọgwụgwọ gachara, mbelata nke cholesterol, LDL, VLDL, triglycerides, wdg. Mmetụta kasịnụ nke iji ọgwụ ahụ ka ahụrụ ka ụbọchị 14 gachara.
Mgbe ị bukwasịrị mbadamba nkume ndị ahụ, a na-enweta ọkwa kachasị elu nke mpaghara ahụ nọ n'ọrụ ka awa ise gachara. Na mgbakwunye, rosuvastatin na-ejikọ nke ọma na protein plasma.
Mwepu nke ihe mejuputara ihe a na - abia, dika iwu, ya na aru ike. Ogologo oge iji ọgwụ ọjọọ maka ọrịa ọrịa imeju nwere ike imetụta oke ọgwụ pharmokokinetic.
Ihe ngosi na contraindications maka ojiji
Dọkịta depụtara ọgwụ hypolipPs maka mgbochi na ọgwụgwọ nke hyzycholesterolemia, atherosclerosis.
Na mgbakwunye, a na-eji ọgwụ ahụ agwọ ọrịa ọrịa obi, yana akụkụ nke usoro ọgwụgwọ dị mgbagwoju anya nke hypercholesterolemia agwakọta.
Ntuziaka maka iji ya nwere ndepụta dị ukwuu nke contraindications. Ha dabere na oke nke ọgwụ.
Amachibidoro iji Krestor 5,10,20 milligrams nye ndị mmadụ:
- nwekwuo uche n'ihe ndị mejupụtara ihe mejupụtara;
- na-arịa ọrịa ọrịa imeju dị njọ, yana mmụba na ọrụ nke transperan hepatic;
- n'otu oge ị underụ ọgwụ cyclosporin;
- mẹ iphe dụ ẹji kfuru;
- nwee ụkọ nke lactose ma ọ bụ ụkọ lactase;
- erubeghị afọ 18;
- na-arịa ọrịa myopathy (pathologies neuromuscular pathologies);
- dị ime ma ọ bụ na-enye nwa ara.
A na-enye ogwu ogwu nke 40 milligram n'ime ndi mmadu:
- Na-a alcoholụ mmanya.
- Na-ata ahụhụ site na ọrịa ịba ọcha n'anya ma ọ bụ akụrụ.
- Ha nwere nnukwu ihe ojoo nke myopathy.
- Were fibrates n'ime ogige ahụ.
- Aweela nnukwu ịwa ahụ n'oge na-adịbeghị anya.
- Na-ata ahụhụ site na ọdịdọ, Akwụkwụ na-adọ.
- Nwee hypothyroidism.
- Ha nwere adịghị agbanwe agbanwe nke elekitirotes n'ime ọbara.
- Na nso nso a nwetara ezigbo mmerụ ahụ.
- Na-ata ahụhụ site na hypotension.
- Oria oria n’isi.
- Na-ata ahụhụ site na nsogbu metabolic.
- N'agbụrụ Mongoloid.
Mpempe akwụkwọ ntụziaka ahụ kwukwara na maka ndị okenye (afọ 60 na karịa), a na-enye ọgwụ ahụ oke oke.
Ntuziaka maka iji ọgwụ ahụ
Ndị okenye na-a theụ ọgwụ n'agbanyeghị n'agbanyeghị nri - n'ụtụtụ ma ọ bụ n'uhuruchi. Mpekere enweghị ike ịta ata ma mebie ya, a na-eji ntakịrị mmiri sachaa ha.
Dọkịta kpebiri na oge ọ ga-eji ya mee ihe, ọ na-eburu n'uche ihe ndị dị ka ogo ọrịa ahụ na njiri mara onye ọrịa ahụ.
Dika ntuziaka ahu si di, ogwu mbu bu 5-10 miligrams. Usoro ọgwụgwọ ya bụ ụbọchị 21, ezumike adịghị mkpa. Ọ bụrụ na ọ dị mkpa, dọkịta nwere ikike ịbawanye usoro ị ofụ ọgwụ ahụ.
A na-atụ aro ike ka ị nyochaa ahụike onye ọrịa na ụbọchị ole na ole mbụ, bụ ndị gbanwere na Krestor 40 milligrams. N'ihi mgbakwunye nke anụ ahụ na akụrụngwa na-arụ ọrụ, mmepe nke ngosipụta na-adịghị mma ga-ekwe omume.
Maka ndị nwere ogo nke gbasara akụrụ, dọkịta na-edepụta usoro izizi nke 5 mg kwa ụbọchị, na-eji nwayọọ nwayọọ na-abawanye ruo 40 mg.
N'ihi eziokwu ahụ bụ na ndị agbụrụ Mongoloid nwere ụfọdụ njirimara nke ọrụ imeju, amachibidoro Krestor 20 na 40 mg. Usoro izizi bụ 5 mg, mgbe ahụ ọ mụbara ruo 10 mg.
A machibidoro ya iwu ịde ihe karịrị 20 mg kwa ụbọchị maka ndị ọrịa na-enwekarị myopathy.
Ekwesịrị idobe ihe na-eme ka egbugbere ọnụ dị nro. Ekwela ka nkwakọ ngwaahịa dabara n'aka ụmụaka.
Ndụ shelf bụ afọ 3, mgbe oge a gasịrị, ị prohibitedụ ọgwụ a machibidoro iwu.
Mmetụta akụkụ na ị andụbiga mmanya ókè
N'ọnọdụ ndị a na-adịghị ahụkebe, mgbe ị na-eji Krestor, mmetụta nwere ike ịpụta.
Dịka iwu, a na-anabata ọgwụ ahụ nke ọma, ma n'oge a na-eji nnukwu ọgwụ, enwere ike ijikwa mmeghachi omume na-adịghị mma n'enweghị ịchọ enyemaka ahụike.
Ntuziaka maka ojiji nwere ndepụta ndị nsonaazụ ndị a:
- Mmeghachi omume nfụkasị - urticaria, rashes na anụ ahụ, edere Quincke;
- nsogbu dyspeptik - stool impa, ọgbụgbọ, ọgbụgbọ, bloating;
- imebi usoro ụjọ ahụ - akpịrị isi na mgbu n’isi;
- ọnụnọ protein na mmamịrị, oge ụfọdụ ihe ọdịda nke ọdịda akụrụngwa;
- olu mgbu, n'ọnọdụ ndị a na-adịghị ahụkebe, ihe omume myopathy;
- mmepe nke ọrịa shuga na-abụghị insulin (ụdị 2) ọrịa mellitus;
- ịba ọcha n'anya, ụba ọrụ nke hepatic transaminases.
Site na ịdoụbiga ọgwụ ókè, mmetụta ya na-abawanye. E gosipụtara ya mebie ọrụ nke akụrụngwa obi yana mgbochi akụrụ na umeji.
Enweghị ọgwụgwọ ọ bụla akọwapụtara, n'ọnọdụ a, hemodialysis adịghị arụ ọrụ. Iji wepu ịdoụbiga ya ókè, a na-eme ọgwụgwọ symptomatic.
Na mgbakwunye, nyocha nke ọma na enzymes imeju dị mkpa.
Mkparịta ụka ọgwụ ndị ọzọ
Mkparịta ụka nke Krestor na ụfọdụ ọgwụ ọjọọ nwere ike ibute nsonaazụ na-adịghị mma. Ya mere, onye ọrịa ahụ kwesịrị ịgwa dọkịta ya na-aga banyere ọrịa niile na - agbakọta iji zere mmeghachi omume na-adịghị mma site n'ahụ ahụ.
Ntụziaka ahụ na-ekwu maka njikọta Krestor na Cyclosporin na-achọghị. Ojiji nke ihe ndị ọzọ na-eme ka mmiri dị ala, dịka ọmụmaatụ, Hemifibrozil, na-agbanwe nsonaazụ plasma nke ihe ọrụ rosuvastatin.
Krestor enweghị nkwekọrịta na Warfarin na vitamin K antagonists, ebe ọ na-emetụta ntụpọ prothrombotic.
A naghị atụ aro ka ị na-ewere Krestor na Ezetimibe n'otu oge, n'ihi na nke a nwere ike ịbawanye ugboro na ogo nke nsonaazụ ya.
Ndị ọrịa na-enwekarị mmalite nke myopathy ekwesịghị iji hemofibrates, fibrates, nicotinic acid, yana gemfibrozil nwere rosuvastatin.
Ọzọkwa, ntinye ya nwere ozi gbasara nchịkwa mgbochi na - achọghị ka oge na - egbochi ọgwụ mgbochi, ọgwụ mgbochi ọnụ, ndị na - egbochi mgbochi. Otu a metụtara ọgwụ dịka Erythromycin, Lopinavir na Ritonavir.
N'ime ọgwụgwọ nke lipids dị elu, a machibidoro ị useụ mmanya na-egbu egbu.
Akwụ ụgwọ na echiche nke n'ji
Nwere ike ịzụta ọgwụ Krestor naanị na ọgwụ dọkịta. Ọzọkwa, ọ dị ọnụ ala karịa ịtụ ntanetị na ntanetị nke ndị nnọchi anya gọọmentị.
Ọnụ ego ahụ dabere na ọnụọgụ blisters na usoro onunu ogwu. A gosipụtara ọnụahịa ọnụahịa n'okpuru:
- Ọnụ ego 5mg (Nke 28) - 1835 rubles.
- Ọnụ ego Krestor 10mg - 2170 rubles.
- 20 mg - 4290 rub.
- 40 mg - 6550 rub.
Ya mere, ọgwụ Krestor dị na ya dị oke ọnụ, yabụ, ọ bụghị ego maka ndị ọrịa na-enweghị ego. Nke a bụ ihe dị mkpa belata ọgwụ ahụ.
Ebe ọ bụ na Krestor pụtara na ahịa ọgwụ ụlọ na-adịghị anya gara aga, enwere ọtụtụ nyocha banyere ya. Edebere ya n’ọrụ nye ndị mmadụ n’otu n’otu maka ọgwụgwọ hyperlipidemia, ọkachasị mgbe ọnya ma ọ bụ nkụchi obi.
Consumersfọdụ ndị na-azụ ahịa na-adọ aka na ntị na isi ọwụwa na nsogbu ihi ụra na-apụta n'oge ọgwụgwọ. Ndị ọkachamara na-enyocha ihe mejupụtara ọbara nke ndị ọrịa, yana ọnụ ọgụgụ enzymes imeju.
N'ozuzu, ndị dọkịta na ndị ọrịa na-akwado mmetụta ọgwụgwọ Crestor.
Ọtụtụ mgbe, enwere ike ịchọta nyocha dị mma banyere ọgwụ.
Mmechi na analogues nke ogwu
Ọ bụrụ na Krestor na-ebute onye ọrịa ahụ, ma ọ bụ na ọ nwere nsonaazụ ndị ọzọ, dọkịta ahụ depụtara onye ga-eji dochie ya.
Nke a puru ibu nmekorita, na ihe mejuputara nke ya na otu aru aru ma obu otu ihe eji eme aru, ma obu ihe ndi ozo di ndu.
N'ime otu mmekorita, ndị kachasị dị irè na ndị a ma ama bụ:
- Mertenil bụ ọgwụ dị ọnụ ala (450 rubles na mkpọ Nke 30 maka 5 mg), nke na-ebelata cholesterol ka uche a na-anabata. Ọ nwere otu ihe na-egosi na contraindications. A na-elezi anya na ndị ọrịa nọ n'ihe egwu dị elu nke ịmalite ọrịa myopathy / rhabdomyolysis, hypothyroidism, na ọdịda akụrụ.
- Rosart bụ ọgwụ ọzọ dị ọnụ ala maka ndị ọrịa nwere obere ego na nke etiti. Ná nkezi, ọnụ ahịa nkwakọ ngwaahịa (Nke 30 maka 5 mg) bụ 430 rubles.
- Rosuvastatin, inwe otu aha ya na ihe eji arụ ọrụ. A ma ama n'etiti ndị ọrịa, ebe ọ bụ na ọnụ ahịa nkwakọ ngwaahịa (Nke 30 maka 5 mg) bụ naanị 340 rubles.
Ihe analogues nke oma gunyere:
- Vasilip nwere mmetụta dị ala, ihe na-arụ ọrụ bụ simvastatin. Onye rụpụtara ya na-emepụta mbadamba nkume nwere usoro ọgwụ nke 10.20 na 40 milligrams. Ọnụahịa nke nkwakọ ngwaahịa (mbadamba 28 kwa 10 mg) bụ 250 rubles.
- Atoris gụnyere mpaghara a na-arụ ọrụ na atorvastatin, nke na-abawanye ọrụ ndị na-anabata LDL na imeju na anụ ahụ extrahepatic. Iwu mgbochi dị ole na ole: hyperensitivity onye, nsị imeju, ụba transaminases, lactation na ime. Ọnụ ego nke Atoris (mbadamba 30 kwa 30 mg) bụ 330 rubles.
- Zokor nwere simvastatin, nke na-egbochi HMG-CoA reductase. Ndị na-emepụta bụ USA na Netherlands. Ọ nwere otu ihe na-egosi na contraindications dị ka ọgwụ ndị gara aga, gụnyere nwata. Ọnụ ego nkwakọ ngwaahịa (mbadamba 28 kwa 10 mg) bụ 385 rubles.
N'ihi ya, ị nwere ike ịtụle mmetụta ọgwụgwọ na ọnụ ahịa ọgwụ, ịhọrọ nhọrọ kachasị mma. Anyị agaghị echefu na na mgbochi na ọgwụgwọ nke atherosclerosis na hypercholesterolemia, ịkwesịrị ịme mmega ahụ ma soro usoro nri.
Ihe oriri pụrụ iche ewezuga oriri nke abụba, eghe, nke achịcha, nke nnu, yana nri nwere nnukwu cholesterol. Enweghị ihe abụọ a, usoro ọgwụ ọgwụ nwere ike ịbụ adịghị arụ ọrụ.
A kọwara Statins n'ụzọ zuru ezu na vidiyo ahụ n'isiokwu a.
