Cocarnit bu nkwadebe di mgbagwoju anya nke nwere vitamin B na triphosadenine. Ejiri iji polyneuropathy na-arịa ọrịa mamịrị, neuralgia, olu mgbu. A na-ejikwa ya iji melite metabolism na ọrịa nke usoro obi.
ATX
A11DA (Vitamin B1).
Cocarnit bu nkwadebe di mgbagwoju anya nke nwere vitamin B na triphosadenine.
Weputara udi ya na ihe mebere ya
Lyophilisate maka nkwadebe nke ụzọ pinkish, ampoules 3 nke 3 ml na ngwugwu mkpụrụ ndụ. Otu ampoule nwere:
- Trifosadenin 10 mg.
- Nicotinamide - 20 mg.
- Cyanocobalamin - 0,5 mg.
- Cocarboxylase - 50 mg.
Ndị ọkachamara: glycine 105.8 mg, ihe eji egbochi (methyl parahydroxybenzoate - 0.6 mg, propyl parahydroxybenzoate - 0.15 mg). Ngwọta: lidocaine hydrochloride - 10 mg, mmiri maka injection - 2 ml.
Omume ọgwụ
Ọgwụ bụ ihe mejupụtara vitamin abụọ, otu coenzyme na ihe metabolic.
Trifosadenin bụ ngwaọrụ nwere agro macroergic nke na-enye ume ike na akwara ozi na akwara obi. Ọ nwere mmetụta hypotensive na antiarrhythmic. Ọ na-abawanye ụbụrụ na akwara. Mma metabolism nke akwara anụ ahụ.
Trifosadenin bụ ngwaọrụ nwere agro macroergic nke na-enye ike akwara obi.
Nicotinamide - vitamin PP, na-etinye aka na usoro ume, mmeghachi omume nke okirikiri nke Krebs. Ọ na - eme ka metabolism na protein metabolism, iku ume cellular. Lowers cholesterol.
Cyanocobalamin - vitamin B12. Mpelata nke ihe a na-eduga n'ọkpụkpụ roba na-ejighị n'aka, ọrụ ndị akwara azụ na akwara azụ. Ọ bụ onyinye ndị dị na methyl iji belata ọkwa nke homocysteine, nke na-emebi sistem obi. Ọ na - akwalite usoro sel.
Cocarboxylase bụ coenzyme nke carboxylase enzyme nke na-ahazi ntinye na ịchụpụ nke otu ọkpọxyl na acid alfa-keto. Na-atụgharị maka antihypoxants, na-eme ka myocardial iguzogide erughi oxygen. Na -ebelata mkpụkọ nke lactate na pyruvate na cardiomyocytes na anụ ahụ. Ekekọtara ọnụ na njikọta nke acids nucleic, protein, abụba.
Mlọ ọgwụ
A na-agbaji Trifosadenin n'ime sel n'ime phosphates na adenosine, bụ ndị agụnyere na usoro nke ịkpụpụta mkpụrụ ndụ ATP maka mkpa anụ ahụ, gụnyere akwara akwara na obi.
Cocarboxylase banye n'ime anụ ahụ, a gụnyere ya na usoro metabolic, wee mebie. A na-apụtakarị ihe dị na mmamịrị na mmamịrị.
A na-ebugharị Cyanocobalamin site na protein transcobalamin n'ime anụ ahụ, nke imeju na-echekwa ya, nke sitere na bile. Ngbanwe nke 5-deoxyadenosylcobalamin. Ihe jikọtara protin bụ 0.9%. Anagide ngwa ngwa mgbe nchịkwa ọnọdụ. Ana-atunye oge kachasị ihe otu elekere oge ịgba ọgwụ intramuscular. Oge iwepụ ọkara ndụ bụ narị ụbọchị ise. Ọ na - abụ akụkụ akụkụ ka eriri afọ - ihe dịka 70-100%, 7-10% na - ahapụ anụ ahụ site na akụrụ. Penetrates na Plasenta, yana n'ime mmiri ara.
Cyanocobalamin bụ nke imeju na-echekwa ya, site na ebe ọ bụ na bile zoro ya.
A na-ekesa Nicotinamide n’ime ahụ niile ngwa ngwa. A na-emegharị ya site na imeju - a na-emepụta nicotinamide-N-methylnicotinamide. Iwepu ọkara ndụ bụ awa 1.3. E weputara ya site na akụrụ, wepu 0.6l / min.
Ihe ngosi maka ojiji
E gosipụtara ya maka ọrịa mamịrị na-arịa ọrịa shuga (goosebumps, ihe mgbu neurogenic), ọrịa obi na akwara obi, neurocirculatory dystonia, na oge mgbe ọ gbakechara site na ọnya obi na nkụchi obi, n'oge ọgụ ọgbụgba na-adịghị ala ala, na-akụda. Ntụziaka maka ojiji na-egosi sciatica, radiculitis.
Ihe ngbanwe
Ọ bụ contraindicated bụrụ na hypersensitivity na ọgwụ, ụba ọbara coagulation, ime, lactation, n'okpuru afọ 18, oké obi ọdịda, thromboembolism, hemorrhagic ọrịa strok, obstructive bronchiitis, bronchial ụkwara ume ọkụ, imeju imeju, ịba ọcha n'anya, exacerbation nke peptic ọnya ma ọ bụ ọnya afọ.
Can nweghị ike iji ọgwụ ahụ maka ọbara mgbali elu na-achịkwaghị achịkwa, hypotension, ịgbatị oge etiti oge QT, ujo cardiogenic, bradyarrhythmias.
Can nweghị ike iji ọgwụ maka ọbara mgbali elu na-achịkwaghị achịkwa.
Uzo esi ewere Cocarnit
Mgbe ị na-a theụ ọgwụ, ịkwesịrị ịma otu esi ewere ya.
Ihe ịmụba
Mee mmanu mmiri nke 2 ml nke 0,5% (10 mg) ma ọ bụ 1 ml nke 1% lidocaine na 1 ml mmiri maka ịgba ntụtụ.
Na-a drugụ ọgwụ maka ọrịa shuga
A na-etinye nsị ahụ n'ime akwara. Usoro ahụ bụ ụbọchị 9 maka 1 ampoule. Mgbe mwepụsịrị ọrịa mgbu na-adịghị ala ala, a na-aga n'ihu na usoro ọgwụgwọ - a na-eme injections ọ bụla ụbọchị 2-3. Ọzụzụ bụ izu 3.
Nsonaazụ
Ọgwụ nwere ike ibute nsonaazụ.
Ọkpụkpụ afọ
Nausea, vomiting, afọ ọsịsa - adịkarịghị.
Ahụhụ Hematopoietic
Mmụba na ọnụ ọgụgụ mkpụrụ ndụ ọbara uhie, sel ọbara ọcha, platelet.
Sistemụ akwara Central
Obi uto, isi ọwụwa, vertigo.
Site n'akụkụ nke sistemụ akwara Central, mmetụta ndị metụtara n'ụdị isi ọwụwa ga-ekwe omume.
Site na anụ ahụ na anụ ahụ dị n'okpuru ala
Site na anụ ahụ na anụ ahụ dị n'okpuru ala - rashes, itching, redness of skin, acne, sweating.
Site na usoro ahụ ji alụso ọrịa ọgụ
Okpukpo nke Quincke, itching, ihe nwesiri.
Site n'akụkụ obi
Arrhythmia, tachy na bradycardia, mgbu obi, ibelata mgbali.
Ahụhụ
Anaaflactic ure, akpukpo aru.
Onye ọrịa ahụ nwere ike ịnwepụta ngosipụta n ’ụdị nfụkasị anụ ahụ.
Ntụziaka pụrụ iche
Treatmentgwọ ọgwụ ọgwụ ahụ kwesịrị ịnwe ọgwụgwọ ọrịa mellitus site na enyemaka nke ọgwụ hypoglycemic. Ọ bụrụ na mgbaàmà na-akawanye njọ ma ọ bụ na enweghị mgbanwe dị mma, a na-edozi atụmatụ ahụ.
A na-eji ihe edozi ahụ ozugbo emechara nkwadebe. Ọ kwesịrị inwe agba pink. Mgbe ọ gbanwere, enweghị ike iji ọgwụ ahụ.
Mmetụta ikike ịchịkwa usoro
Nsonaazụ enwere ike - nkụda mmụọ, mmụọ adịghị ọcha. Mgbe ha mere, ịnweghị ike ịkwọ ụgbọala na usoro dị mgbagwoju anya.
Nsonaazụ enwere ike - nkụda mmụọ, mmụọ adịghị ọcha.
Jiri n'oge ime na lactation
Contraindicated. Mgbe ị na-a theụ ọgwụ ahụ, ha na-ajụ inye nri.
Usoro ọgwụgwọ Cockarnit maka ụmụaka
A ogwu contraindicated ruo afọ 18.
Jiri na agadi
Dose ukpụhọde adịghị.
Dodoụbiga ya ókè
N'ihi ọdịnaya nke vitamin PP na iji ogologo oge, ọgwụ ahụ nwere ike ibute ọrịa imeju na-egbu egbu n'ihi ụkọ nke ndị otu methyl. N'iburu nju nke cyanocobalamin, ọkwa folic acid na-ebelata.
Mmekọrịta na ọgwụ ndị ọzọ
Cyanocobalamin ekwekọghị na vitamin B1, B2, B6, folic, ascorbic acid, ọla dị arọ (De-nol, Cisplatin), mmanya.
Cyanocobalamin ekwekọghị na mmanya.
Site n'iji biguanides (Metformin) na-emekọ ihe ọnụ na ọgwụ glucose ọgwụ mgbochi ọrịa aminoglycoside, salicylates, potassium, colchicine, anticonvulsants, na-ebelata vitamin B12.
Iji zere hypercoagulation, ị gaghị eji ọgwụ ọgwụ ndị na-abawanye viscosity ọbara.
Cyanocobalamin ekwekọghị na chloramphenicol.
Na-eme ka mmetụta vasodilating nke dipyridamole nwee.
Purines - kafiin, Theophylline - ndị na - emegide ọgwụ.
Mgbe ejiri glycosides cardiac mee ihe, ohere nke mmetụta ndị ọzọ na-abawanye.
Nicotinamide na-akwalite mmetụta nke nchekasị, ọgwụ mgbochi na ọgwụ na-ebelata nrụgide
Xanthinol nicotinate na-ebelata ọgwụ ọgwụ.
Emeputa
World Medical Limited.
Analogs
Onweghi ego na otu ihe mebere. Ma, enwere ọgwụ metabolic - sodium adenosine triphosphate, cocarboxylase, mbadamba acid nicotinic, cyanocobalamin.
Ahịa ọgwụ na-ahapụ okwu
Relelị site na ndenye ọgwụ. Ndepụta B.
Ọnụ ego maka Cocarnith
Forgwọ maka ampoules atọ bụ 636 rubles.
Ọnọdụ nchekwa nke ọgwụ Kokarnit
Chekwaa n'ebe kpọrọ nkụ na okpomọkụ nke + 15 ... + 25 Celsius С.
Bọchị mmebi
Afọ 3 Ihe mgbaze bụ afọ 4.
Nyocha banyere Kokarnit
Nastya
Ọgwụ ahụ adịghị ọnụ ala, mana a na - ewepụ ihe mgbu ya na radiculitis kpamkpam. Akpọrọ injections 12.
Catherine V.
Ọrịa shuga 2dị nke Abụọ bụ nnukwu ọrịa. Ọ na-egosipụta onwe ya na mgbu na ogwe aka na ụkwụ. O gafere izu 3. Ọrịa polyneuropathy nwere mbelata nke ukwuu. Ọ dị mfe ije ije.
Peter
Enwere m arịa ọrịa shuga 2 na ọrịa angina pectoris. Dọkịta nyere iwu ka iji ọgwụ were ụbọchị ọ bụla were ọgwụ ọjọọ ahụ wee bepụ ya. Anọgidewo m na-akụ ihe ụbọchị 5, ahụike m akala mma, mgbu m na aka m nwetụrụ ntakịrị. Ọbụna nrụgide ahụ belatara ntakịrị ka ihe mgbu obi belata.
