A na-egosi Metformin 500 maka nchịkwa ọrịa shuga. Ọrịa a dị iche na ọrịa ndị ọzọ site na mgbasa ngwa ngwa na ọnwu ọnwụ. Ọgwụ shuga bụ otu n’ime ọrụ dịịrị ndị dọkịta gburugburu ụwa.
International Nonproprietary Aha
Aha aha a bụ Metformin.
ATX
A10BA02.
Ha weputara udi ya na ihe mebere ya
A na-emepụta ha n’ụdị mbadamba. Ihe mejupụtara ya nwere ọgwụ ọgwụ metformin hydrochloride na ngwa inye aka: silicon dioxide, magnesium stearic salt, copovidone, cellulose, Opadry II. A naghị emepụta ọgwụ ahụ na nsị.
A na-ekepụta ha n’ụdị mbadamba, ihe mejupụtara ya nwere ọgwụ metformin hydrochloride na ihe inyeaka.
Omume ọgwụ
Metformin (dimethylbiguanide) nwere mmetụta antidiabetic na-arụ ọrụ. A na - ejikọta mmetụta bio bio ya na ikike nke igbochi usoro gluconeogenesis na ahụ. N'okwu a, itinye uche nke ATP na sel na-ebelata, nke na-akpali mmebi nke sugars. Ọgwụ na-abawanye ụba nke glucose na-esikwa n’ebe extracellular oghere banye n’ime sel. Enwere mmụba na ụba nke lactate na pyruvate na anụ ahụ.
Ọgwụ na-ebelata ike nke mbibi abụba, na-egbochi nguzobe abụba na-enweghị atụ.
N'oge a na-eji biguanides eme ihe, a na-ahụta mgbanwe nke insulin, na-eduga n'ibelata nwayọ nke ọ̀tọ glucose n'ọbara. Ọ naghị akpali insulin site na mkpụrụ ndụ beta, nke na-enye aka na enyemaka ahụike hyperinsulinemia (insulin na-abawanye n'ime ọbara).
N'ime ndị ọrịa nwere ahụike, ịnwe Metformin anaghị eduga n'ọbara shuga. N'okwu a, a na - ewere ya iji lụso oke ibu ọgụ n'ihi mgbochi agụụ, belata ike nke nnabata glucose site na eriri afọ ma banye n'ọbara.
O nwekwara ngwongwo hypolipPs, ya bụ, ọ na-ebelata ọnụ ọgụgụ dị ala nke lipoproteins dị ala maka mbube nke onherosclerotic plaques. O nwere uru bara uru na arụ ọrụ nke akwara ọbara na obi, na-egbochi ọdịdị nke angiopathy (mmebi veins na akwara art na ọrịa shuga).
Mlọ ọgwụ
Mgbe nlekọta nke mbadamba ihe dị n'ime, ihe kachasị maka dimethylbiguanide ruru mgbe elekere 2.5 gachara. 6 awa mgbe ojiji nke esịtidem, usoro absorption si eriri afọ eriri afọ akwụsịla, mgbe nke ahụ gasịrị, mbelata nke ukwuu nke Metformin na plasma ọbara.
Ntinye na usoro ọgwụgwọ ọgwụgwọ na-enyere aka ịnọgide na-etinye uche nke ọgwụ na plasma n'ime 1-2 μg na 1 liter.
Iji ọgwụ eme ihe na nri na-ebelata nnabata nke ihe na-arụ ọrụ na plasma. Mkpokọta ogwu na-aputa na eriri afọ, afọ, gland. Usoro ndu nke ogwu a di 60%. Ihe nchebe Plasma adịghị ejikọ ọnụ nke ọma.
Ejiri akụkụ akụrụ ya were ihe dịka 30% agbanweghị. Ejikọtara ọnụ ọnụ nke ogige ahụ site na umeji.
Ntinye na usoro ọgwụgwọ ọgwụgwọ na-enyere aka ịnọgide na-etinye uche nke ọgwụ na plasma n'ime 1-2 μg na 1 liter.
Ihe ngosi maka ojiji
Edere ọgwụ ahụ maka ụdị 1 ọrịa shuga. Ọ bụ mgbakwunye na usoro ọgwụgwọ shuga bụ isi (iji insulin ma ọ bụ ọgwụ na-ebelata glucose). N'ọnọdụ ọrịa shuga na-akpata insulin, a na-enye ya ọgwụ naanị yana yana insulin. Typedị ọrịa shuga nke 2, enwere ike ịkọ ọgwụ monotherapy.
A na-atụkwa aro maka ịgwọ oke ibu, ọkachasị ma ọ bụrụ na usoro a chọrọ nlebara anya glucose ọbara.
Ihe ngbanwe
Contraindicated na ndị a:
- afọ ime afọ 15;
- hypersensitivity na metformin yana akụkụ ndị ọzọ nke mbadamba;
- precoma;
- dalfunction na akụrụngwa (ọdịda akachasị creatinine kpebiri);
- ketoacidosis;
- anụ ahụ necrosis;
- ahu akpukpọ aru nke aru na aru.
- ọnya afọ nke ọrịa mamịrị;
- ajọ ọrịa na-efe efe;
- steepụ nke onye ọrịa;
- nnukwu obi ọgụ;
- ụkpa adrenal;
- nri nwere calorie n'okpuru 1000 kcal;
- afọ imeju;
- lactic acidosis (gụnyere na n'ime anamnesis);
- mmanya riri ahụ;
- ọrịa na-adịghị ala ala nke na-akpata ụnwụ oxygen anụ ahụ n'ime mmadụ;
- ahụ ọkụ
- nnukwu mmerụ ahụ, ihe ịwa ahụ, oge ọrụ;
- ihe a na-eji ụdị rediopaque ọ bụla nwere ayodiin;
- xxụ nnukwu mmanya na ethanol;
- ime
- lactation.
A naghị anabata ndị ọrịa mmanya riri ahụ ka ha were Metformin 500.
Jiri nlezianya
Ekwesịrị ịkpachara anya mgbe ị na-ewere ihe ndị na-ewetara shuga n'ihi ihe dị ize ndụ nke mmeghachi omume hypoglycemic. Ọrịa dị mkpa ịgbaso iwu nke nri na-eri nri, na-esochi otu oriri nke carbohydrates kwa ụbọchị. N'ịba ụba nke ahụ, a ga-eji obere ego.
Uzo esi ewere Metformin 500
A na-ewere mbadamba okwu ọnụ, na-enweghị atụ, ya na ọtụtụ mmiri. Ọ bụrụ na ọrịa nwere nsogbu ilo mmiri, mgbe ahụ, a na-ahapụ ya ka ọ kee mbadamba ahụ ụzọ abụọ. Ọzọkwa, ọkara nke abụọ nke ọgwụ ahụ kwesịrị ị beụ mmanya ozugbo emesịrị nke mbụ.
Tupu ma ọ bụ mgbe nri
A na-enweta nnabata naanị mgbe nri gachara.
Na-a drugụ ọgwụ maka ọrịa shuga
N'ime ọrịa shuga, a na-enye usoro izizi nke mbụ na mbadamba 2 nke 500 mg. Enweghi ike kewa ya na uzo abuo ma obu ato: nke a na - enyere aka mee ka ike nke ihe ndi mmadu ghara isi ike. Mgbe izu abụọ gachara, ọnụọgụ ahụ na-abawanye n'ogo mmezi - mbadamba 3-4 nke 0,5 g nke ọ bụla.
A na-ewere Metformin 500 naanị mgbe nri gasịrị.
N'ihe banyere iji Metformin nwere insulin, usoro ya agaghị agbanwe. Mgbe nke a gasịrị, a na -ebelata mgbanye nke insulin buru. Ọ bụrụ na onye ọrịa riri ihe karịrị 40 nkeji. Nkwekọrịta insulin, mbelata ọnụ ọgụgụ ya ga-anabata naanị na ọnọdụ ụlọ ọgwụ.
Etu ị ga - esi were maka oke ibu
Maka ịbelata oke, a na-enye ọgwụ ọgwụ 0,5 g ugboro abụọ n’ụbọchị, dị njikere mgbe ị risịrị nri. Ọ bụrụ na nsonaazụ nke oke ibu ezughi oke, mgbe ahụ ka enyere ọgwụ ọzọ nke 0,5 g Ogologo oge ọgwụgwọ maka ibu belata ekwesịghị ịbụ izu 3. Uzo ozo gha emeghachiri ma obu mgbe onwa gasiri.
Na usoro ifelata i kwesiri igha egwu.
Oge ije
Ọkara ọkara nke dimethylbiguanide bụ awa 6.5.
Nsonaazụ nke Metformin 500
Mmepe nke mmetụta ndị na-apụta ugboro ugboro.
Ọkpụkpụ afọ
Nsonaazụ ndị kachasị emetụta bụ: ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, mbelata nke agụụ, mgbu n'ime afọ na eriri afọ. Ọtụtụ mgbe ndị ọrịa nwere ike ịnwe mmetụta dị iche iche nke ọla n'ime oghere ọnụ.
Nsonaazụ kachasị emetụta bụ mgbu na afọ na eriri afọ.
Ihe ịrịba ama ndị a na-egosi naanị na mmalite nke iji ọgwụ ma mesịa pụọ. Achọghị ọgwụgwọ pụrụ iche iji belata mgbaàmà ndị a.
Site n'akụkụ nke metabolism
Ọ bụ ihe nwute na onye ọrịa ịrịa ọrịa lactic acidosis. Ọnọdụ a chọrọ ịkagbu.
Na anụahụ
N'ihe banyere hypersensitivity na ndị ọrịa, mmeghachi omume anụ ahụ n'ụdị ọbara ọbara nke epidermis na itching nwere ike ime.
Usoro endocrine
N’oge na-adịghị anya, enwere ike ịchọpụta ndị ọrịa nwere ọrịa thyroid ma ọ bụ nsogbu nke glandalis gland.
Ahụhụ
Mmeghachi omume nfụkasị ahụ na-eme naanị na ịbawanye ụba nke ịdị n'otu ahụ. Mmadu nwere ike itolite: erythema, itching, redness nke aru site na ụdị urticaria.
N'ihe banyere hypersensitivity na ndị ọrịa, mmeghachi omume anụ ahụ n'ụdị ọbara ọbara nke epidermis na itching nwere ike ime.
Mmetụta ikike ịchịkwa usoro
Enweghị mmetụta na-adịghị mma na ikike ịkwọ ụgbọala ndị siri ike ma kwọọ ụgbọ. Ekwesịrị ịkpachara anya mgbe ị na-edepụta Metformin yana ọgwụ ndị ọzọ na-ebutelata shuga, n'ihi na ha nwere ike belata ọkwa shuga n'ụzọ dị egwu. A na-atụghị ịnya ụgbọ ala n'ọnọdụ a iji zere ihe ọghọm nke ihe ọghọm.
Ntụziaka pụrụ iche
Ojiji nke ogwu a jikọtara ya na ụfọdụ atụmatụ. Ekwesịrị igosipụta nlezianya na mmepe nke nkụda obi, akụrụ gbasara akwara, na imeju. N'oge usoro ọgwụgwọ, a chọrọ iji nyochaa glucometer.
A na-akagbu ọgwụ ahụ ụbọchị 2 tupu yana n'ime ụbọchị 2 mgbe fluoroscopy na-eji ndị na-egbu redio. A ga-emerịrị otu ihe ahụ ma ọ bụrụ na enyere onye ọrịa ahụ usoro ịwa ahụ n'okpuru ọgwụ mgbochi ma ọ bụ ọgwụ mpaghara.
Site na mmepe nke ọrịa nke urinary na akụkụ nke akụkụ ahụ, ịkwesịrị ịkpọtụrụ dọkịta ngwa ngwa.
Jiri n'oge ime na lactation
Amachibidoro ị whenụ ya mgbe ị na-ebu nwata ma na-a breastụ ara.
Cribdebe Metformin na ụmụ 500
Maka ụmụaka gbara afọ 15, ọgwụ anaghị enye ya ọgwụ.
Jiri na agadi
N'ime ndị okenye, ọ dị mkpa idozigha usoro ọgwụgwọ. A naghị atụ aro ka ndị ọrịa dị otú ahụ kọwaa ọgwụ ole ọ na-anara. Ekwesịrị iji usoro ọgwụgwọ na-akwado nkwado iji belata nsonaazụ ya. Mgbe ụfọdụ, Metformin 400 edepụtara ya.
Ngwa maka ọrụ ezughi oke ọrụ
N'ọnọdụ nrụrụ akụrụ, a ga-eji ọgwụ jiri ọgwụ a. Ọ bụrụ na ọrịa mamịrị nephropathy amalitewo, mgbe ahụ a ga-ewepụ ọgwụ ahụ, n'ihi na iji ya nwere ike ịkpasu mmebi ahụ ọzọ. Otu n'ime ebumnuche ịgwọ ọrịa shuga bụ igbochi mmepe nke ọdịda akụrụ na mbibi ụwa.
N'ihe banyere nkwarụ akụrụ, iji ọgwụ akpachara anya, ọ bụrụ na ọrịa mamịrị nephropathy amalitela, mgbe ahụ ịkagbu ọgwụ ahụ.
Jiri maka ọrụ imeju na-arụ ọrụ
Site na nkwarụ imeju, a drunkụrụma ọgwụ ahụ na akpachapụ anya. Iche iche na oke mmebi nke anụ ahụ na - eme ka akwara gbanwee. Ekwesịrị iji nlezianya nyochaa njirimara ndị na-emepụta ihe na mwepu osisi na biochemical.
Do Overụbiga ihe oke n’ime Metformin 500
Dodoụbiga mmanya ókè nwere ike ibute lactic acidosis, mana ọ naghị etolite hypoglycemia. Mgbaàmà nke lactic acidosis:
- vomiting
- afọ ọsịsa
- mgbakasị ahụ n’afọ;
- mmụba dị nkọ na mmiri;
- olu mgbu
- mgbu n'ime afọ.
Ọ bụrụ na enweghị nlekọta ahụike n'oge oge a dizziness, dizziness na-amalite. N'ọdịnihu, Coma na - eme.
Jiri nkwụsị ya na mmepe nke acidosis. A na-ebunye onye ọrịa ahụ ụlọ ọgwụ ngwa ngwa. Zọ kachasị dị irè iji mee ka anụ ahụ dọọsị anụ ahụ bụ ịba ọcha n'anya.
Enweghị nlekọta ahụike n'oge oke ị ,ụbiga mmanya ókè, dizzness, dizzness na-amalite.
Mmekọrịta na ọgwụ ndị ọzọ
Ekwesịrị ịkpachara anya na ọnọdụ nke sistemụ sulfonyl-urea na insulin. Onwere ihe ndi mmadu nwere ike ime bu onugbu obara n’obara onye obia. A na - eji ọgwụ ndị a belata hypoglycemic nke biguanides:
- ndị na - arụ ọrụ glucocorticosteroid nke usoro na ọrụ mpaghara;
- ihe ndị na-eme ka a gbanwee ihe;
- glucagon;
- nhazi adrenaline;
- progestogens na estrogens;
- nkwadebe nke ihe choro site na gland thyroid;
- ngwaahịa nicotinic acid;
- thiazide diuretics;
- phenothiazines;
- Cimetidine.
Welie uto hypoglycemic:
- Ndị na - egbochi ACE;
- beta-2 adrenergic antagonists;
- Ndị na - egbochi MAO;
- Cyclophosphamide na ihe atụ ya;
- PVP nile na - abụghị steroidal;
- Oxytetracycline.
Ekwesịrị ịkpachara anya na ọnọdụ nke sistemụ sulfonyl-urea na insulin.
Iwere ndi nwere ndi ayodiin nwere ihe omuma banyere ihe X-ray na - agbanwe metabolism nke Metformin, o bu ya mere o bidoro igosi mmetuta. Ọ nwere ike ibute oke nsogbu gbasara akụrụ.
Chlorpromazine na-egbochi mwepụta insulin. Nke a nwere ike ịchọ mmụba na metformin.
Nnukwu oriri nke biguanides na-eme ka ịba ụba nke Amilorid, Quinine, Vancomycin, Quinidine, Cimetidine, Triamteren, Ranitidine, Procainamide, Nifedipine.
Mmanya ndakọrịta
Mmanya na-abawanye n'ihe ize ndụ nke lactic acidosis. N'oge ọgwụgwọ, ị ga-ezere iji ihe ọholicụ alcoụ na-egbu egbu na ọgwụ na ngwaahịa niile ethanol nwere, n'ihi na ha enweghị mmekorita na Metformin.
Analogs
Analogs bụ:
- Mpempe;
- Glucophage;
- Siofor;
- Metformin Siofor;
- Metformin Long;
- Mpempe Metformin;
- Metformin Zentiva;
- Akpa;
- Metfogamma;
- Langerine;
- Glycomet.
Formmetin nwere ike ime dị ka analogues nke ọgwụ Metformin 500.
Ahịa ọgwụ na-ahapụ okwu
Akwụkwọ ọgwụ dọkịta ka achọrọ. E kwesịrị ide aha ngwaahịa a na Latin.
Enwere m ike ịzụta na ndenye ọgwụ
Amachibidoro ire ọgwụ ọgwụ na ahịa ọgwụ na-enweghị ndenye ọgwụ.
Medication -ụ ọgwụ onwe ya nwere ike imetụta ọnọdụ onye ahụ na nsogbu ma kpatara nnukwu hypoglycemia.
Ọnụ ego maka Metformin 500
Ọnụ ego ọgwụ ọjọọ na Russia bụ ihe ruru 155 rubles. kwa mbadamba 60 nke mbadamba.
Ọnọdụ nchekwa maka ọgwụ
A ga-echekwara na ụlọ okpomọkụ ke nkụ.
Bọchị mmebi
Ogwu ahụ dabara adaba maka afọ 3.
Emeputa
A na-emepụta ọgwụ ahụ na ụlọ ọrụ Indoco ịgba ọgwụ ltd, L-14, Verna Industrial Mpaghara, Verna, Salcete, Goa - 403 722, India, Teva Pharmaceutical Enterprises Ltd. Na Russia, mmadụ nwere ike ịchọta ọgwụ emepụtara na ụlọ ọrụ Gedeon Richter.
Nyocha banyere Metformin 500
Na ntanetị ị nwere ike ịgụ nyocha nke ndị ọkachamara na ndị ọrịa riri ọgwụ ahụ.
Ndi dibia
Irina, dị afọ 50, endocrinologist, Moscow: “Metformin na analogues ya - Glucofage na Siofor - na - enyere aka ịchịkwa ụzọ ọrịa ahụ ma belata ọkwa shuga. Ọgwụ ahụ na-anabata ọgwụ ndị ọrịa, ọ bụ naanị obere oge ka ngosipụta nke iwe afọ na-amalite na ụbọchị mbụ nke ọgwụgwọ. Asụ ọgwụ a chọrọ nke ọma na-ebelata mkpa anụ ahụ insulin na-arịa ọrịa shuga. "
Svetlana, 52 afọ, endocrinologist, Smolensk: "Ọrụ nke ọgwụgwọ ọrịa shuga dị mma bụ ịnọgide na-enwe ọ̀tụ̀tụ̀ shuga n'ime ókè a na-egbochi ya na igbochi mmepe nke nsogbu ndị dị ize ndụ. Metformin na-anagide ọrụ ndị a nke ọma. N'ime ndị ọrịa na-a ,ụ ọgwụ, glycemic index kacha nso na nkịtị."
Ndị ọrịa
Anatoly, afọ 50, St. Petersburg: "Metformin nyere aka igbochi mmalite nke hyperglycemia. Sugar ugbu a anaghị abawanye karịa 8 mmol / L. Ahụ dị m mma. Ana m ewere Metformin 1000 dịka ntuziaka ahụ si dị."
Irina, onye dị afọ 48, Penza: “akingakingụ ọgwụ, belatara oriri nke insulin.Ọ ga - ekwe omume idobe ihe ntụgharị glycemia n'ime oke nke dọkịta tụrụ aro. Mgbe ọgwụ ndị a gachara, mgbu akwara wee pụọ, ọhụụ wee gbakee. ”
Ibelata ibu
Olga, onye dị afọ 28, Ryazan: "Site n'enyemaka nke Metformin 850, enwere ike iji belata ibu site na 8 n'arọ yana nri nwere obere kalori na obere carb. Enwere m mmetụta dị mma, enweghị m nkụda mmụọ ma ọ bụ nkụda mmụọ.
