Etu esi eji ọgwụ Blocktran GT?

Blocktran GT bụ ọgwụ a na-edepụtakarị maka ọbara mgbali elu. Ogwu a na acho acho ogwu a bu ka onodu kwesiri ekwesi ma belata onu ahia.

International Nonproprietary Aha

Aha ejiri mara aha mba ụwa bụ Losartan.

Blocktran GT bụ ọgwụ a na-edepụtakarị maka ọbara mgbali elu.

ATX

Dika nhazi nke ogwu, ATX: C09DA01.

Losartan jikọtara ya na diuretics.

Ha weputara udi ya na ihe mebere ya

A na-ewepụta ọgwụ ahụ n'ụdị mbadamba okirikiri, nke ọ bụla na-eji mmiri na-eji mmiri soluble eme ihe. Agba nke shei ahụ nwere ike ịbụ pink, enwere odo odo.

N'ime ihe mejupụtara ọgwụ ahụ, ihe ndị na-arụ ọrụ na-arụ ọrụ:

• potassium losartan;
• hydrochlorothiazide.

Ndepụta nke ihe inyeaka gụnyere:

• microcrystalline cellulose;
• lactose monohydrate;
• nduku;
• povidone;
• steeti magnesium;
• sodium stachi glycolate;
• colloidal silicon dioxide.

Ngwakọta nke losartan na hydrochlorothiazide na-enye aka na-ebelata ọbara mgbali elu.

Mpekere mbadamba ihe ndị a mejupụtara:

• polydextrose;
• hypromellose;
• talc;
• ọkara yinye triglycerides;
• titanium dioxide;
• dextrin;
• mmiri carmine na-acha ọbara ọbara soluble (E120).

Omume ọgwụ

Ihe mgbagwoju nke losartan na hydrochlorothiazide nwere ngwongwo antihypertensive. N'ihi nke a, mbelata ọbara mgbali na-adị ike karịa mgbe ị na-eji akụkụ nke ọ bụla. Ọnụnọ nke mmetụta diuretic so na:

• mkpali nke mmepụta nke aldosterone;
• ụba ọrụ nke plasma retin;
• ịba ụba nke angiotensin II;
• belata ọkwa potassium.

N'ihi ọdịnaya nke losartan, ọgwụ ahụ dị n'aka ndị otu antagonensin 2. ndị na-anabata nnabata .. Ọ naghị egbochi kinase II (enzyme a bụ mbibi nke bradykinin).

Ogwu a anaghị emechi homonụ ndị ọzọ na ọsịsị ion ndị na-emetụta arụ ọrụ nke sistem obi.

Ihe dị n’ime ahụ na - edozi usoro dị iche iche n’usoro obara n’otu oge:

• na-ebelata ọbara mgbali elu na nrụgide na akwara ọbara;
• na-ebelata itinye uche nke norepinephrine na aldosterone na plasma ọbara;
• belata ọnụego OPSS;
• nwere mmetụta diuretic;
• na-ebelata mgbe ibuchara;
• na-enyere aka iwelie ndidi nke ndị ọrịa nwere nkụchi obi na-emega ahụ.

N'okwu a, ọgwụ ahụ anaghị egbochi mgbochi nke homonụ ndị ọzọ na ion nke na-emetụta arụ ọrụ nke usoro akwara obi.

Hydrochlorothiazide nwere akụrụngwa nke antihypertensive na diuretic. Ihe omume ya bu ka achagharia ozo nke electrolytes di na tubules gbasara akwara. Enwere ike ịbawanye na ịta uric acid. Mgbe nchịkwa ọnụ gasịrị, akụrụngwa amalite ime ihe mgbe awa 2 gachara. A na-enweta oke arụmọrụ mgbe awa anọ gachara. Ogologo oge nwere ike ịdị iche site awa isii ruo awa iri na abụọ.

Mlọ ọgwụ

Mmetụta antihypertensive mgbe otu ọgwụ were ruo oke ya ka awa 6 gachara. N'ime awa 24 ndị na-esote, a na-eji nwayọọ nwayọọ belata nsonaazụ ya. Mkpochapụ ọgwụ na ọgwụ metabolites bụ 600 ml / min na 50 ml / min, n'otu n'otu.

Mwepu nke ihe na - arụ ọrụ sitere na akụrụ na eriri afọ (tinyere bile).

Mwepu nke ihe na - arụ ọrụ sitere na akụrụ na eriri afọ (tinyere bile).

Ihe ngosi maka ojiji

Edere ọgwụ maka ọgwụ ndị a:

1. Ọbara ọbara. A na-eji ọgwụ ahụ eme ihe maka ọgwụgwọ na prophylactic ebumnuche.
2. Hypertrophy nke ventricle aka ekpe. E gosipụtara ọgwụ a maka mgbochi ọrịa na ọrịa obi.

Ihe ngbanwe

Iji ọgwụ ọjọọ eme ihe na-enweghị ndenye ọgwụ dọkịta na-ada mbà. Enwere ọtụtụ contraindications:

• hypersensitivity na otu ma ọ bụ ọtụtụ ihe na mejupụtara;
• afọ ụmụaka rue afọ 18 (amụbeghị ihe mmetụta nke arụ ọrụ ike n'ahụ ahụ ụmụaka);
• ọnụnọ nke ọrịa glucose-galactose malabsorption syndrome, ụkọ lactase ma ọ bụ enweghị ntinye nke lactose;
• oge ime na oge inye nwa ara;
• akụkọ ihe mere eme nke ọrịa imeju, cholestasis;
• Ọrịa Addison;
• akpịrị ịkpọ nkụ;
• nnukwu ọgbụgba ọbara ike;
• Ọrịa akụrụ (ma ọ bụrụ na mwepụ creatinine erughị 30 ml / min);
• ngbaka
• hypokalemia refractory;
• hyperkalemia
• ọrịa shuga mellitus siri ike ịchịkwa.

Can nweghị ike iji ọgwụ a na-enweghị ndenye dọkịta maka hypotension arterial hypotension.

Can nweghị ike iji ọgwụ a na-enweghị ọgwụ dọkịta maka ọrịa Addison.

Ọ gaghị ekwe omume iji ọgwụ ahụ na-enweghị ndenye dọkịta maka ọrịa imeju siri ike.

Jiri nlezianya

Na ọnụnọ nke ọrịa ụfọdụ ọ dị mkpa maka nlezianya usoro ịhọrọ nke ọma. N'okwu a, a na-enyocha dọkịta mgbe niile maka ọnọdụ onye ọrịa ahụ. N'iji nlezianya dezie, etinyere mbadamba nkume n'ọnọdụ ndị a:

• stenosis (mitral na aortic);
• oge mgbake mgbe a gbasesịrị akụrụ;
• ihe mgbochi obara nke anakpo hypertrophic;
• ọnụnọ nke nnukwu obi daa;
• isi hyperaldosteronism;
• ọrịa ụbụrụ;
• angioedema.

Etu ị ga - ewere Blocktran GT

Mbadamba dị maka nchịkwa ọnụ. Nri anaghị emetụta pharmacokinetics, yabụ, a na-eri ọgwụ ahụ n'oge ọ bụla dabara adaba: tupu nri, n'oge nri, ma ọ bụ mgbe nke ahụ gasịrị.

A na-ahụta ọkọlọtọ kwa ụbọchị dịka 1 mbadamba, were otu oge. Ugboro - oge 1 kwa ụbọchị.

N'ọnọdụ ụfọdụ, olu a nwere ike ọ gaghị eweta mmetụta ọgwụgwọ achọrọ, mgbe ahụ, n'okpuru nlekọta dọkịta, ọ ga-ekwe omume ịbawanye ọgwụ ahụ na mbadamba 2 kwa ụbọchị. Ekwesiri kesaa olu a ụzọ abụọ. Ọtụtụ mgbe usoro ọgwụgwọ a bụ maka ndị ọrịa nwere ọbara mgbali elu.

Na-arịa ọrịa shuga

Na ọgwụgwọ ndị ọrịa na-arịa ọrịa shuga kwesịrị nyochaa ọnọdụ onye ọrịa ahụ mgbe niile.

Site na irighiri akwara na akwara anụ ahụ, ike ọgwụgwụ na-ekwe omume.

Nsonaazụ nke Blocktran GT

Mmetụta ọgwụ ndị na-apụta site na iji ọgwụ nwere ike metụtara usoro ahụ dị iche iche. Ọdịdị na - adịghị ike na - apụta na ụbọchị mbụ iwere mbadamba mbadamba, a na - ewepụ nwayọọ nwayọọ.

Ọkpụkpụ afọ

Ndị na-abaghị uru bụ afọ ntachi na mgbu afọ. Ọ nwere ike ịbụ ekpomoku, akpọnwụ akpọnwụ, gastritis, sialadenitis, pancreatitis, hyponatremia.

Ahụhụ Hematopoietic

Site na sistem okirikiri ọbara na akwara oria, anaemia na-achọpụtakarị ndị ọrịa. Leukopenia, agranulocytosis, thrombocytopenia, na purpura adịkarịghị eme.

Sistemụ akwara Central

Site na sistemụ akwara na akwara anụ ahụ, ike ọgwụgwụ, asthenia, dizzness, ehighị ụra na isi ọwụwa ga - ekwe omume.

Obere oge, ụra, adịghị ike, nchekasị, neuropathy nsogbu, ncheta ihe, oke nke oke, nkụda mmụọ, ọgba aghara na ụtọ, ụda na tinnitus, conjunctivitis, na mwepu nke mmụọ.

N'ime nsogbu ndị kachasị emetụta usoro urinary, a na-akpọ oria urinary.

Site na usoro urinary

Otu n'ime nsogbu ndị a na-ahụkarị na usoro urinary bụ ndị a na-akpọ oria urinary na-efe efe, nwere mbelata nwoke na nwoke, ọrụ akwara nwere nsogbu, yana ọdịdị urination peremptory. Hydrochlorothiazide n'ọnọdụ ụfọdụ nwere ike ibute glucosuria, nephritis interstitial.

Site na sistem iku ume

Patientsfọdụ ndị ọrịa na-eme mkpesa nke mkpọchi imi, ụkwara na akara nke ọrịa na-emetụta ọnya elu akụkụ (n'etiti ha sinusitis na pharyngitis). A na-ejikarị ọkụ ọkụ ọkụ.

Ọrịa ndị na-adịkarị obere bụ rhinitis, bronchitis, mkpụmkpụ ume, ọnya ụkwara ume ọkụ, oyi baa.

Na anụahụ

Theụ ọgwụ ahụ nwere ike ibute akpọnwụ akpọnwụ, eserese, hyperemia, ọsụsọ nke anụ ahụ nke ukwuu, necrolysis na-egbu egbu, ụdị akpụkpọ ahụ nke lupus erythematosus.

Site na usoro akwara

A na-ahụkarị seizures, mgbu azụ, myalgia, mgbu n'ụkwụ na obi. Arthralgia, fibromyalgia na ọrịa ogbu na nkwonkwo bụ ihe ndị a na-ahụ anya dị ka ngosipụta ndị a na-adịghị ahụkebe.

Site na usoro akwara ahụ mgbe ọ theụsịrị ọgwụ ahụ, a na-ahụkarị ihe ọdịdọ.

Site na usoro akwara obi

Mmetụta ndị ọghọm n’oge ọgwụgwọ nwere ike ịbụ:

• mmụba obi;
• orthostatic hypotension;
• arrhythmia;
• angina pectoris;
• bradycardia;
• na-arịa ọrịa vasculitis;
• ihe mgbu n’obi.

Ahụhụ

Allergy bụ mmeghachi omume hypersensitivity na otu akụkụ nke ọgwụ ahụ. Ọ na-esite na itching, urticaria, ihe ngbu, angioedema.

Mmetụta ikike ịchịkwa usoro

N’oge a na-a theụ ọgwụ ahụ, ndị ọrịa nwere ike ịnwe nsonaazụ ndị ọzọ dịka ụra ụra, mbelata nke ịta ahụhụ na anya nke ọgbụgba na enweghị mmụọ. Maka nke a, a ga-akpachara anya mgbe ị na-anya ụgbọala na itinye aka na egwuregwu nwere ike ịdị ize ndụ.

Ntụziaka pụrụ iche

Blocktran nwere ikike ime ka mkpocha ọbara serin creatinine na urea ọbara. Mgbanwe ndị a na - apụtakarị na ndị ọrịa chọpụtara na ọnya akụrụ ma ọ bụ akwara akwara.

Allergy bụ mmeghachi omume hypersensitivity na otu akụkụ nke ọgwụ ahụ.

Jiri n'oge ime na lactation

Na ọgwụ, enweghi data gbasara nsị ọgwụ a na ahụike yana ọnọdụ nwa ebu n'afọ. N'okwu a, ọgwụ ahụ na-emetụta RAAS, nke a na nchepụta echiche nwere ike ibute mmepe na ọnwụ nwa ebu n'afọ mgbe ị na-a medicineụ ọgwụ na oge nke abụọ na nke atọ nke afọ ime.

Ọ bụrụ na ọ dị mkpa iji ọgwụ mee ihe na ọgwụgwọ nke ụmụ nwanyị na-enye nwa ara, ndị dọkịta na-atụ aro ịkwụsị inye nwa ume, ebe mmiri ara ara nwere obere losartan.

Oge umuaka Blocktran GT

Achọpụtaghị data maka ịdị irè nke ọgwụ n'oge nwata. Maka nke a, ụmụaka enyeghị ọgwụ ọgwụ.

Jiri na agadi

N'ihi nnwale ụlọ ọgwụ, ọ dịghị ihe egwu ọ bụla mgbe ị na-a aụ ọgwụ ole. Notzụlite dose adịghị atụ aro.

Ndị ọkachamara machibidoro ị ofụ ọgwụ a mgbe a na-enye nwa ara.

Ngwa maka ọrụ ezughi oke ọrụ

N'ọnọdụ ụfọdụ, ị theụ ọgwụ ahụ kpatara arụ ọrụ akụrụ. A kọwara nke a site na mgbochi nke RAAS, nke na-apụta mgbe ị takingụ ọgwụ. Ọrịa ndị dị otú ahụ bụ nwa oge ma kwụsịchaa mgbe ịkwụsị ọgwụ.

Iji kpachara anya, ekwesịrị ịnye ndị mmadụ nsogbu na akwara umeji ọgwụ a.

Ngwa maka ọrụ imeju na-arụ ọrụ

N'ihi ọmụmụ ihe banyere ọgwụ, e gosipụtara mmụba dị ukwuu na losartan n'ọbara nke ndị ọrịa chọpụtara ọrịa imeju. Maka nke a, a na-ebelata usoro onunu ogwu arụ ọrụ.

Njuputa nke Blocktran GT

Ceedingụ ọgwụ dọkịta nyere gị na-edugakarị ịdoụ ọgwụ ọdoụdoụ. Ejiri mara ya n'ọdịdị nke ọbara mgbali dị ala, tachycardia, bradycardia. Chmazu oke hydrochlorothiazide kpatara hypochloremia, hypokalemia, hyponatremia. Ikekwe ụba arrhythmias.

N'ihi ọmụmụ ihe banyere ọgwụ, e gosipụtara mmụba dị ukwuu na losartan n'ọbara nke ndị ọrịa chọpụtara ọrịa imeju.

Iji mee ka ọnọdụ onye ọrịa dịzie mma, ndị dọkịta na-eme ọgwụgwọ diuresis ma mee ọgwụgwọ Symptomat. N'okwu a, ọrịa ịba ọcha n'anya anaghị arụ ọrụ.

Mmekọrịta na ọgwụ ndị ọzọ

Edere Angiotensin II onye na-emegide antagonist n'ọnọdụ ụfọdụ ka enyebere ya dịka akụkụ nke ọgwụgwọ mgbagwoju anya. N'okwu a, losartan na-emekọrịta ihe n'ụzọ dịgasị iche na ọgwụ ndị ọzọ:

1. Ntinye ya na Aliskiren ka akwadoghi n’ihi nsogbu nke ibute ọrịa n’arụ n’arụ na nnukwu hypotension.
2. Na ACE inhibitors. Ọtụtụ mgbe, enwere ọdịdị nke ọdịda akụrụ, syncope, hypotension ma ọ bụ hyperkalemia.
3. N'iji oge nke iji ọgwụ ọmịiko ma ọ bụ ndị na - egbochi ọgwụ na - eduga na nkwalite mmekọrịta nke ọgwụ.
4. Potassiumnweta ọgwụ na-enye ike n’egwuregwu, ọtụtụ ndị ọrịa na-etolite ọ̀tụ̀tụ̀ potassium dị elu n’ahụ.
5. Site na fluconazole na rifampicin, a na-ebelata mmetụta losartan.
6. Na barbiturates na narcotic analgesics. Enwere nnukwu ihe nrịba osthostatic hypotension.
7. Na ọgwụ hypoglycemic. Imeghari usoro onunu ogwu di nkpa, ebe obula oru ogwu lara n’ibelata.

Mmanya ndakọrịta

Iwere mbadamba nkume bụ ihe a na-achọghị oke mma ka ijikọta ya na ị ofụ mmanya na-aba n'anya. Ime ụdị ihe a nwere ike ibute nsonaazụ na-adịghị mma. Hydrochlorothiazide na ọnụnọ ethanol nwere ike ịkpata hyperension orthostatic.

Analogs

Ọgwụ nwere ọtụtụ analogues nke ndị ụlọ ọrụ Russia na ndị si mba ọzọ mepụtara. N'ime ha bụ mkpụrụ ndụ ihe nketa na ọgwụ ndị nwere otu ụdị mmetụta:

• Vazotens H;
• Lorista N;
• Gizaar Forte;
• Presartan H;
• Simartan-N;
• Gizortan.

N'etiti analogues nke Blocktran GT, Vazotens N.

N'etiti analogues nke Blocktran GT na-ekenye Lorista N.

N'etiti analogues nke Blocktran GT, Gizaar Forte bụ ihe ama ama.

Ahịa ọgwụ na-ahapụ okwu

Nwere ike ịzụta ọgwụ site na ndenye ọgwụ.

Enwere m ike ịzụta na ndenye ọgwụ

Ogwu sitere na otu angiotensin II receagonor antagonists dị naanị na ndenye ọgwụ.

Ahịa Blocktran GT

Ọnụ ego ọgwụ ọjọọ ahụ na-adabere na usoro onodu ogwu nke mbadamba. Ọnụ ego dị na ụlọ ahịa ọgwụ na Moscow sitere na 220 rubles. kwa mkpọ (mbadamba 30).

Ọnọdụ nchekwa maka ọgwụ

Ebe a ga-echekwa ọgwụ ahụ ga-adị nkụ, chebere ya site n’anwụ. Ọnọdụ okpomọkụ - ọ dịghị elu karịa + 25 Celsius С.

Bọchị mmebi

N'okpuru ọnọdụ nchekwa ọgwụ ahụ, ndụ nchekwa nke mbadamba ihe ahụ ruru ọnwa 24 site na ụbọchị ewepụtara. Mgbe oge a gasịrị, a machibidoro ọgwụ a ike.

Emeputa

A na-emepụta ọgwụ ahụ nke Pharmstandard-Leksredstva OJSC. Companylọ ọrụ na-emepụta ọgwụ dị na Kursk na adreesị: st. Ọgbakọ nke abụọ, 1a / 18.

Nyochaa Blocktran GT

Alexander, gbara afọ 48, Volgograd

Ewere ọgwụ ahụ dịka akụkụ nke ọgwụgwọ zuru oke mgbe ọ nwesịrị nsogbu ọbara mgbali elu. N’oge gboo, isi ọwụwa na ike ọgwụgwụ bilitere. Dọkịta dụrụ ọdụ ịghara ịnara. N’izu nke abụọ, mmetụta ndị ahụ kwụsịrị. Emezigharị ọzụzụ ahụ.

Tatyana, 39 afọ, Khabarovsk

Anọwo m na-arịa ọbara mgbali elu kemgbe ọtụtụ afọ. Ọgwụ na-eme ihe ngwa ngwa ma dị irè. Tupu oge ahụ, dọkịta ahụ depụtara mbadamba nkume ndị ọzọ, mana ha ewetaghị nsonaazụ ọ bụla.