Latren bụ ndị otu vasodilaị ebe ọgụ na - eme. Ejiri ya na usoro ọgwụgwọ iji mepụta mmetụta vasodilating. Effectdị ọgwụgwọ ahụ dị mkpa iji weghachite mgbasa ọbara nkịtị na mpaghara anụ ahụ emetụtara yana imeziwanye akwara ozi nke ọbara. Ọgwụ na - enyere aka iwepụ thrombosis, atherosclerosis na nsogbu nke choroid nke akụkụ anụ ahụ.
International Nonproprietary Aha
Pentoxifylline.
Latren na - enyere aka wepu thrombosis, atherosclerosis na nsogbu nke choroid nke anụ ahụ.
ATX
C04AD03.
Ha weputara udi ya na ihe mebere ya
A na-eme ọgwụ ahụ n'ụdị ihe ngwọta maka nkwadebe nke infusion. Sdị usoro onunu ogwu dị na ampoules iko nwere 100, 200 ma ọ bụ 400 ml nke onyinye na - arụ ọrụ - pentoxifylline. N ’anya, ihe ga - eme bu mmiri iyi na - achapu acha odo odo ma obu nke n’enweghi odo. Dịka ihe ndị ọzọ iji meziwanye nnabata, a na-eji ụdị sodium lactate, mmiri mmiri maka ntụtụ, potassium na sodium chloride.
Omume ọgwụ
A na - ekekọta Pentoxifylline site na methylxanthine; ọ bụ ndị otu nke akụkụ ọgba aghara. Ngwongwo ọgwụ ọgwụ bụ ihe na-egbochi phosphodiesterase. N’akụkụ ahụ, ihe kemịkalụ na-enye aka na nchịkọta nke 3,5-AMP n’ime akwara dị mma nke votkụla endothelium, sel ọbara, n’akwara na akwara.
Pentoxifylline na-egbochi ịgbachi mkpụrụ ndụ ọbara uhie na platelet ọbara, na-enye nkwupụta ma na-abawanye nguzogide nke mkpụrụ ndụ ha. N'ihi ngbako nke mkpokọ, viscosity ọbara na-ebelata, nsonaazụ fibrinolytic na-abawanye ma nwekwaa ihe ọmụmụ nke ọbara.
Remata Latrena na - enye aka na onodu otiti obi.
Pentoxifylline na-enye aka na mmụba na plasma ịta fibrinogen. N'okwu a, akụrụngwa nọ n'ọrụ na-ebelata nguzogide n'obere akwara, na-enwe mmetụta vasodilating na-adịghị ike na akwara akwara. Theakingụ ọgwụ ahụ na-enyere aka ịhazi oke obi. N'ihi imetuta ọgwụgwọ ọgwụgwọ, microcirculation ọbara na mpaghara ischemic na-abawanye: ihe gbasara elele na-ebute ụnwụ oxygen nke mkpụrụ ndụ na-ebelata, anụ ahụ na-enweta oke oxygen na nri.
N'ime usoro ọmụmụ nke ụlọ ọgwụ, enwere mmetụta dị elu nke ọgwụ ahụ n'ihe ndina ahụ nwere akụkụ akwara, usoro akwara na-enwe mmetụta, yana ihe mmetụta dị elu na arịa ụgbọ mmiri. Ogwu nwere mmetụta na-adịghị ike na mgbasawanye nke akwara ọbara.
Mlọ ọgwụ
Mgbe pentoxifylline batara n’arụ ọbara vaskụla, ọ na-erute ogo kachasị elu na ọbara n’ime nkeji iri isii. N’isi nke mbụ site na hepatocytes, ihe dị n’ọrụ na-enwo mgbanwe zuru oke. Ngwa ahịa ire ere karịrị ọkwa pentoxifylline nke plasma kachasị elu ugboro abụọ ma nwee ọgwụgwọ ọgwụgwọ. Ọkara ọkara bụ 1.6 awa. 90% nke ọgwụ na-ahapụ ahụ ahụ n'ụdị metabolites, 4% ka enwere oria na anụ ahụ n'ụdị mbụ ya.
Ihe ngosi maka ojiji
Pentoxifylline bụ vasodilator nke na-eme ka ọrụ ọrụ nke capillaries rụọ ọrụ. Ọgwụ na - enyere aka belata nro nke akwara ọbara, bronchospasm. A na - enye ọgwụ vasodilator maka nsogbu mgbasa na mpaghara anya nke anya megide mgbanwe na-emebi emebi na akwara votkụl na nku anya. Ọgwụ na - enyere aka ịbawanye mgbasa ọbara n'ọbara nke trophic ọnya ma ọ bụ gangrene nke ala ala.
Ọgwụ na-enyere aka n'ịgwọ ọrịa nke ọrịa na-enweghị atụ nke ọrịa akwara na ọrịa etiology, dị ka:
- imebi anụ ahụ trophic;
- mgbu na akwara nke aka na ezumike;
- njupụta oge;
- veins varicose.
Ọgwụ a na eweghachi ọrịa ụbụrụ yana inye ọbara anụ ahụ, na - enyere aka wepu osụbọ ọbara ma na - eme ka mkpụrụ ndụ akwara zoo site na nrịanrịa polyneuropathy. A na-eji ọgwụ ahụ agwọ ọrịa Raynaud's syndrome.
Ihe ngbanwe
Amachibidoro ọgwụ a ka enye ya ndị nwere ọgwụ na-emetụta ihe ndị na-ebute ndabere nke Latren, yana ọgwụ xanthine. A naghị akwado ọgwụ ahụ maka iji ya mee ihe n'ihu ọrịa na ọrịa ndị na-esonụ:
- nnukwu ọbara ọgbụgba;
- hemorrhagic diathesis;
- nsogbu ga-ebute mmepe ma ọ bụ ọnụnọ nke infarction na-arịa nnukwu ọrịa myocardial;
- Ọrịa porphyrin;
- ọbara ọgbụgba;
- pathological obi rhythm nsogbu;
- mgbanwe mgbanwe atherosclerotic siri ike na endothelium nke akwara ọbara na akwara akwara;
- ọbara mgbali ala;
- ọbara ọgbụgba n'ụbụrụ.
A naghị akwado ọgwụ a maka ndị nwere ọrịa imeju na akụrụ.
Jiri nlezianya
Ndị mmadụ na-arịa ọnya afọ nke ọnya afọ na nke duodenum kwesịrị inyocha ọnọdụ nke usoro pathologies n'oge ọgwụgwọ Latren. Ekwadoro ịkpachara anya maka ndị nwere nkụchi obi na ọnụnọ nke ọrịa shuga mellitus. Edere ọgwụ ahụ n'okpuru nlekọta ahụike siri ike mgbe ọwachara ahụ ogologo.
Uzo esi ewere Latren
A na-enye ọgwụ ahụ n'ọtụtụ ọgwụ ka infusion. A na-ehiwe usoro onunu ogwu site n'aka dibia banyere ihe banyere usoro a na akparamaagwa nke onye ọrịa. Nke a gụnyere oke ahụ, afọ, ọrịa na-efe efe, ịnagide ọgwụ, ogo nke nsogbu ọbara.
A na-atụ aro ndị ọrịa karịrị afọ 12 ka ha tinye ọgwụ ụra iji 100-200 ml nke ọgwụ. A na-aga n'ihu nchịkwa nke ịkwọ ụgbọala maka awa 1.5-3. N'inwe nnabata dị mma, a na-anabata mmụba onunu ihe ruru 400-500 ml (nke kwekọrọ na 300 mg) maka ntụtụ.
Oke onunu ogwu a na-anabata kwa ubochi ruru 500 ml. Ná nkezi, ọgwụ ọgwụ na-adị ihe dị ka ụbọchị 5-7. Ọ bụrụ na ọ dị mkpa, ịgaghị n'ihu na-agbanyere nchịkwa nke vasodilators n'ime mbadamba ụrọ.
Na-arịa ọrịa shuga
Ọgwụ nwere ike ịkwalite mmetụta hypoglycemic nke ọgwụ antidiabetic, ya mere, n'oge ọgwụgwọ na Latren, ọ dị mkpa ịchịkwa ọkwa nke glucose n'ọbara ma buru shuga. Nke ikpeazụ a dị mkpa iji gbochie mmepe nke hypoglycemia.
Mmetụta akụkụ Latrena
Mmeghachi omume na-apụta na ị doụ ọgwụ adịghị mma.
Na akụkụ ahụ nke ọhụụ
Eleghi anya mbelata nke anya a na-ahụ anya, mbufụt nke conjunctiva, ọbara mbufụt, mgbada ihu. N'ọnọdụ ndị na-adịghị ahụkebe, nkwarụ anya na-esote mmepe nke scotoma.
Site na anụ ahụ na akwara
N'ọnọdụ ụfọdụ, adịghị ike akwara na mgbu.
Ọkpụkpụ afọ
Site n’imebi usoro nri na-ewe iwe, mmadụ na-amalite inwe nkụja, ọgbụgbọ. N'ọnọdụ ndị na-adịghị ahụkebe, mmebi nke eriri afọ eriri afọ, mbufụt nke imeju na-amalite, cholecystitis njọ. Ọdịdị nke cholestasis ga-ekwe omume.
Ahụhụ Hematopoietic
Mbelata mgbochi ụmị ọkpụkpụ na mwelata nke ọnụ ọgụgụ ọbara ọbara uhie na platelet, nke nwere ike iduga mmepe nke anaakpo hypoplastic. N'ọnọdụ ndị siri ike, enwere ọnwụ.
Sistemụ akwara Central
Site na iji usoro ezighi ezi, isi na-amalite ịda mbà, enwere isi ọwụwa, ihe ngbanye aka, nkwonkwo akwara, nsogbu ụra. Obi mmadụ na-enwe nchegbu na-enweghị isi.
Site na sistem iku ume
Ikekwe mmepe nke mkpụmkpụ ume.
Na anụahụ
A na-enwe mmeghachi omume anụ ahụ na rashes, itching, erythema na ọrịa Stevens-Johnson. A na-eme ka ọgbụgba nke efere ntu ahụ.
Site na usoro akwara obi
Ọrịa ahụ na-amalite ịnya isi, ukwu aka ya. Enwere tachycardia, mgbanwe na ọbara mgbali. N'ọnọdụ siri ike, ọbara ọgbụgba nwere ike ịmalite.
Site n'akụkụ nke metabolism
Ikekwe mmepe nke anorexia, mbelata nke ọkwa potassium, ọsụsọ na mmụba ahụ, ọrụ nke enzymes imeju na-abawanye.
Ahụhụ
Ihe nfụkasị ahụ na-eso mmeghachi omume anụ ahụ na mmeghachi omume anaphylactoid.
Mmetụta ikike ịchịkwa usoro
N'iburu n'uche mbelata ike ịgba ọsọ psychomotor na ịta ahụhụ n'oge ịgwọ ọrịa ọgwụ, ọ dị mkpa izere ịnya ụgbọ ala na ngwaọrụ mgbagwoju anya.
Ntụziaka pụrụ iche
N'ihe banyere lupus erythematosus na ọrịa ndị ọzọ metụtara akwara njikọ, ọ dị mkpa ịkọ ọgwụ ahụ naanị mgbe nyochachara nke ọma banyere uru na ihe ọghọm dị. Achọrọ nnwale maka ọbara oge ọ bụla n'ihi ihe enwere ike ịnwe akpasasị akwara akpụ.
Ọrịa nwere nkụda mmụọ na-adịghị ala ala kwesịrị iru ọkwa nke ụgwọ ọbara tupu iji ọgwụ.
Ekwesịrị ịnwale ndị ọrịa na mmepe mmeghachi omume anaphylactic maka ịnagide ọgwụ. Maka mmeghachi omume dị mma, a na-akagbu ọgwụ.
Jiri na agadi
Ndị gaferela afọ iri ise ga-akpachara anya.
Ibugharia umuaka Latren
Rarelymụaka na-erubeghị afọ iri na abụọ ka etinyere ọgwụ Latren. Maka umuaka, odi nkpa igbako usoro onwonye ya - 10 ml nke ogwu n’otu kilogram nke aro. Maka ụmụ amụrụ ọhụrụ, a na-agbakọ kwa ụbọchị kwa ụbọchị n'otu ụzọ ahụ, mana ọnụọgụ kachasị kwesịrị ịgaghị 80-100 ml.
Jiri n'oge ime na lactation
Onweghi data na uzo esi abanye pentoxifylline na nsonaazụ ya na mmepe ẹmbrayon. Yabụ, a na-agunye ọgwụ mgbochi intraven naanị n'ọnọdụ dị oke njọ, mgbe mmetụta vasodilating nke ọgwụ nwere ike gbochie ihe egwu na ndụ nne. Mmetụta ọgwụgwọ kwesịrị ịgabiga ihe ọghọm nke intrauterine n’ime akpa nwa.
N'oge a na-enye nwa ara, mgbe ị na-ahọpụta Latren, ọ dị mkpa ịkwụsị ị laụ ara.
Ngwa maka ọrụ ezughi oke ọrụ
Ọrịa akụrụ na-abawanye ọkara ndụ nke ọgwụ ahụ, ya mere, a na-anabata mkpụrụ ndụ Latren intraven naanị na ọnụnọ nke ọrịa akụrụ dị nwayọ na oke.
Jiri maka ọrụ imeju na-arụ ọrụ
Anaghị anabata ọgwụ a maka ndị nwere mmebi imeju.
Latren overdose
Site n'ị abuseụ ọgwụ ọjọọ, mgbaàmà ndị a na-apụta:
- ike adighi ike;
- Dizziness
- mkpịsị akwara neuromuscular;
- wedata ọbara mgbali;
- ọgba aghara na enweghị uche;
- obi mmụba;
- ihu iru;
- ọgbụgbọ na ọgbụgbọ;
- ọbara ọgbụgba na ọbara ọgbụgba n'ime oghere nke digestive;
- ogwe akwara;
- ahụ ọkụ.
Onye a tara ahụhụ chọrọ ụlọ ọgwụ ngwa ngwa. A na-eme ọgwụgwọ iji gbochie mmepe nke ọbara ọgbụgba n'ime na iwepu ihe ịrịba ama nke ịdoụbiga mmanya ókè.
Mmekọrịta na ọgwụ ndị ọzọ
Pentoxifylline nwere ike ịkpalite mbelata nke ịkpụcha shuga plasma ma na-eji ndị ọrụ hypoglycemic ma ọ bụ insulin. Ya mere, ndị ọrịa nwere ọrịa shuga kwesịrị ịkpọtụrụ onye ọrịa endocrinologist iji dozie usoro nke ọgwụ antidiabetic.
N'ime usoro ịzụ ahịa, enwerela ikpe nke ịba uru ọbara na iji ọgwụ mgbochi ọgwụ K, ana - echekwa na anagaghị. Mgbe ejikọtara ya na ọgwụ ọgwụ ndị a, ọ dị mkpa ileba anya n'ihe omume anticoagulant.
Pentoxifylline na-akwalite mmetụta antihypertensive nke ọgwụ antihypertensive. N'ihi ya, hypotension akwara nwere ike ịdapụta.
A na-ahụta ekweghị ekwe anụ ahụ mgbe ị na-agwakọta Latren na ọgwụ ndị ọzọ na-agwọ otu ọgwụ.
Akụrụngwa nọ n'ọrụ na-abawanye ọkwa Theophylline, ọ bụ ya mere iwe ọkụ ma ọ bụ mee ka ọ pụta ugboro nke ọdịdị nke mmetụta na-adịghị mma site na iji Theophylline.
Mmanya ndakọrịta
Enweghi ike ijikọ ọgwụ na ọgwụ ethanol nwere ọgwụ na ngwaahịa mmanya. Mmanya ethyl bụ ihe ngọngọ nke pentoxifylline, na-akwalite nrachi nke sel ọbara, na-egbochi mgbasa ọbara. Ethanol na-akpata vasospasm na mmepe nke thrombosis. Enwere enweghi ọgwụgwọ ọgwụgwọ na nbilata.
Analogs
Analogues nke otu ọgwụ nwere njiri mara otu ọgwụ ma ọ bụ ihe mejupụtara kemịkalụ:
- Trental;
- Bilobil;
- Pentoxifylline;
- Ifuru;
- Agapurin;
- Pentilin.
Ahịa ọgwụ na-ahapụ okwu
A naghị ere ọgwụ a na-enweghị ihe ngosi ngosipụta ahụike ọ bụla.
Enwere m ike ịzụta na ndenye ọgwụ
Achọrọ ndenye ọgwụ maka na ere Latren anaghị akwụ ụgwọ. Incorrectsụ ọgwụ vasodilator na-ezighi ezi nwere ike ibute nsonaazụ oke ma ọ bụ mmetụta dị oke njọ.
Ọnụahịa
Onu ogugu onu ahia nke onu ogugu nke onu di ihe di iche site na 215 ruo 270 rubles.
Ọnọdụ nchekwa maka ọgwụ
Ọ dị mkpa iji chekwaa ihe ngwọta na okpomọkụ nke + 2 ... + 25 Celsius C n'ebe ọkpọ nkụ, dịpụrụ iche site na ìhè anyanwụ.
Bọchị mmebi
Afọ 2
Emeputa
Yuri-Farm LLC, Russia.
Nyocha
Ulyana Tikhonova, 56 afọ, St Petersburg
Enyere usoro maka thrombosis. Na mbido, a na - ejikọ ndị Latren na inpura heparin, emesia a bufere ha ka ha were mbadamba. Infusion enyere igbari ọbara ọbara, ọzịza apụla. Echere m na ezigbo ngwakọta ọnụahịa na mma. Enweghị mmetụta ọ bụla, mana ịhapụ ị alcoholụ mmanya na ise siga n'oge ọgwụgwọ. Dọkịta ahụ kwuru ka ịgbasochi ntuziaka maka ojiji iji belata ohere nke ọrịa.
Leopold Kazakov, 37 afọ, Ryazan
Edere m Latren ọgwụ site n'aka otolaryngologist, onye m mere mkpesa banyere mbelata ịnụ ntị yana ọdịdị nke tinnitus dara. Ihe kpatara ya bu mmepe nke dystonia. Infusions nyere aka iwepụ isi ọwụwa, na-akụ ntị. Achọpụtara m na ọhụụ nkịtị. Nsonaazụ gosipụtara n'ụdị belata ọbara mgbali elu. Iji kpochapụ ha, achọrọ mbelata usoro onunu ogwu. Dọkịta nọ na-aga ga-eme mgbanwe. Anaghị m adụ gị ọdụ ka ị dozie usoro onunu ogwu gị, n'ihi na enwere ihe ize ndụ nke ịdoụbiga mmanya ókè na mmeghachi omume dị njọ na ahụ.
