Lysiprex bụ ọgwụ ezubere maka ọgwụgwọ nke ọrịa obi na akwara vaskụla. Nyere ike nke ikpe ahụ, a na-eji ya na ọgwụ ndị ọzọ ma ọ bụ dịka ngwa nnwere onwe. Iji nwee usoro akụrụngwa na-arụ ọrụ nke ọma na ọrịa na-adịghị ala ala, a na-enye ọgwụ ọgwụ maka nchịkwa prophylactic.
International Nonproprietary Aha
Lisiprex.
ATX
S.09.A.A. 03 Lisinopril.
Lysiprex bụ ọgwụ ezubere maka ọgwụgwọ nke ọrịa obi na akwara vaskụla.
Ha weputara udi ya na ihe mebere ya
Mbadamba ụrọ, ihe na-arụ ọrụ n'ime ha bụ 5, 10 na 20 mg. Isdị ahụ dị okirikiri, dị larịị. Agba dị ọcha. Akụkụ bụ isi: lisinopril, nke edochiri lisinopril dihydrate. Ihe ndi ozo: hydrogen phosphate anhydrous, mannitol, magnesium stearate, stachi ọka.
Omume ọgwụ
Agụnyere ọgwụ a na otu nke ACE inhibitors. Lisinopril na-ebelata ọrụ nke ACE (enzyme angiotensin-na-agbanwe). N'ihi nke a, a na-ebelata ọ̀da nke angiotensin nke ụdị nke mbụ ruo na nke abụọ, nke nwere mmetụta vasoconstrictive ma na-akpali mmepụta nke aldosterone site na cortex adrenal, belatara.
Ọgwụ na-ebelata nrụgide na obere arịa ọbara nke ngụgụ, na-amụba nguzogide olu olu. Ọ na-eme ka a na-ahụkarị ọgwụ endothelium, ọrụ ndị ọ na-arịa n'ọrịa na hyperglycemia.
Ihe nọ n'ọrụ na-agbasa mgbidi akwara karịa karịa na-emetụta bed venous. Site n'iji ọgwụ ahụ ogologo oge, hypertrophy cardiac myocardial na-ebelata. Ngwá ọrụ ahụ nwere ike belata nsị nke mkpụrụedemede mkpụrụedemede nke aka ekpe, mee ka ọnọdụ ndị mmadụ butere nkụchi obi sie ike.
Mlọ ọgwụ
Theakingụ ọgwụ ahụ enweghị nri na nri. Usoro itinye aka na-agafe ruru 30% nke ihe ndị dị n'ọrụ. Bioavailability bụ 29%. Indgbakwunye protein protein dị ntakịrị. N’agbanwe agbanwe, isi ihe na ihe inyeaka na-abanye n’ọbara.
A na-ahụta ndọta kachasị plasma n'ime elekere isii. Fọrọ nke a esighi na metabolism. A na - agbanwe ya site na mmamịrị na mmamịrị. Ọkara ndụ na-ewe awa 12.5.
Gịnị ka enyere ya?
Ihe ngosi maka ojiji nke lysiprex:
- ụdị mkpa hypotension akwara ozi;
- ọrịa mamịrị nephropathy;
- ọrịa obi na-adịghị ala ala;
- nnukwu myocardial infarction.
Na nnukwu nkụchi obi, a ga-ewere ọgwụ ahụ n’ụbọchị mbụ mgbe mbuso agha gbochiri mmerụ ahụ ventricle obi ekpe.
Ihe ngbanwe
Ọrịa nlekọta ọrịa na-amachi nchịkwa Lysiprex:
- hypersensitivity na otu akụkụ nke ọgwụ ahụ;
- ọnụnọ nke edebe Quincke na akụkọ banyere ezi na ụlọ;
- mkpụrụ ndụ ihe nketa na mmeghachi omume dị ka angioedema.
Ekwekọrịtara nke contraindication, na ọnụnọ nke eji ikike nke Lysiprex, ma jiri nlezianya na nlezianya na-atụle ọnọdụ onye ọrịa ahụ:
- mitral stenosis, aortic, akwara akwara;
- cardioac ischemia;
- mmepe nke hypotension akwara;
- oke nrụrụ akụrụ;
- ọnụnọ nke potassium ịba ụba na ahụ;
- autoimmune connective anụ ahụ na-arịa.
Amachibidoro iji ọgwụ na ọgwụgwọ nke ọrịa obi na ndị ọrịa bụ ndị nnọchite agbụrụ ojii.
Etu esi ewere lisiprex?
Mbadamba nkume ndị ahụ na-ata ata na-ata ata, n'agbanyeghị nri. Nkezi a tụrụ aro ka ị recommendedụọ bụ 20 mg kwa ụbọchị, egosiri ike ịnwe kwa ụbọchị bụ 40 mg. A na-agbakọ oge ọgwụgwọ ọ bụla n'otu n'otu, dabere n'ịdị ọcha nke ọrịa ahụ na ogo mgbaàmà ya. Mmetụta ọgwụgwọ nke ị theụ ọgwụ ahụ na-apụta mgbe ụbọchị 14-30 gasịrị.
Usoro onunu ogwu maka monotherapy nke nkụchi obi na-adịghị ala ala: usoro izizi - 2.5 mg kwa ụbọchị. Maka ụbọchị 3-5, mmụba gaa na 5-10 mg kwa ụbọchị ga-ekwe omume. Hapụrụ kachasị bụ 20 mg.
Usoro ọgwụgwọ mgbe usoro nkụchi obi gasịrị na 24 awa mbụ mgbe ọgụ ahụ gasịrị: 5 mg, kwa ụbọchị ka a na-emeghachi ọgwụ ahụ n'otu usoro onunu ogwu. Mgbe ụbọchị abụọ gachara, ịkwesịrị ị 10ụ ọgwụ mg 10, na-esote ụbọchị, a na-emeghachi dose ahụ na usoro 10 mg. Ọgwụgwọ ahụ nwere ike ịdị izu anọ ruo izu isii.
Ọrịa mamịrị na-arịa ọrịa shuga - ihe ruru 10 mg kwa ụbọchị, n'ihe banyere nnukwu onyonyo Symptomatic, enwere ike ịbawanye usoro onunu ogwu ya ka ọ bụrụ ihe kwesiri ekwesi kwa ụbọchị nke 20 mg.
Na-arịa ọrịa shuga
Ntinye shuga anaghị agbanwe agbanwe n’okpuru lisiprex. Treatmentgwọ ndị ọrịa nwere ụdị nchọpụta ahụ anaghị agbazi usoro onunu ogwu.
Mmetụta akụkụ nke lisiprex
Ọtụtụ mgbe enwere mmetụta ndị dị ka isi ọwụwa, ụra na enweghị mmasị, ọgbụgbọ, tachycardia na wedata ọbara mgbali elu, mmeghachi omume nfụkasị anụ ahụ. Ọrịa ndị ọzọ a na-adịghị ahụkebe: mmepe nke myalgia, vasculitis, arthralgia.
Ọkpụkpụ afọ
Ọrịa afọ ọsịsa, ọgbụgbọ na ọgbụgbọ.
Ahụhụ Hematopoietic
Mbelata nlebara anya haemoglobin, mmepe nke agronulocytosis. N’oge na-adịghị anya - mmụba na ESR n’enweghị ọnụnọ nke usoro mkpali n’ahụ.
Sistemụ akwara Central
Mwakpo isi ọwụwa na eze, isi ike akwara.
Site na usoro urinary
Ọrịa ọgbụgba, nhụjuanya, nnukwu obi daa.
Site na sistem iku ume
Paroxysmal ụkwara na-enweghị amamịghe sputum.
Na anụahụ
Urticaria, itching na anụahụ. Ọsụsọ gabigara ókè, ọdịdị nke alopecia enwere ike.
Site na usoro akwara obi
Ọkụ na obi, obere oge - hypotension arterial. N’oge na-adịghị anya - tachycardia, bradycardia, onyonyo na-ese onyinyo nke nkụda obi.
Usoro endocrine
Esemokwu ndị a na - adịkarị anya bụ drenfunction adrenal.
Site n'akụkụ nke metabolism
Mmụba creatinine mụbara. N'ime ndị nwere ọrịa akụrụ na ọrịa shuga, urea nitrogen na-abawanye.
Ahụhụ
Oria akwara, mmepe nke anakpa.
Ọ bụ ihe na-adịghị mma ịchịkwa akụrụngwa dị mgbagwoju anya maka ndị na-enwe ọgbụgbọ na isi ọwụwa mgbe ị na-ewere Lisiprex.
Mmetụta ikike ịchịkwa usoro
Ọ bụ ihe na-adịghị mma iji nye ndị ọrụ akụrụngwa dị mgbagwoju anya, n'azụ ị Lyụ Lysiprex, nwere nsogbu na usoro ụjọ ahụ: isi, isi ọwụwa.
Ntụziaka pụrụ iche
Edeghị ọgwụ maka ndị ọrịa chọpụtara ọrịa ọria obi na akwara. Amachibidoro ịnye ọgwụ ahụ na nnukwu ọrịa myocardial infarction, ma ọ bụrụ na enwere nnukwu ihe ọ bụla nwere nkwarụ hemodynamic.
Tupu ịmalite ọgwụgwọ, ọ dị mkpa iji nyochaa akụrụ. Akpachara anya, naanị na ọnụnọ nke ihe ngosi pụrụ iche, mgbe ọgwụ ndị ọzọ enweghị ike inye ọgwụgwọ ọgwụgwọ achọrọ, a na-enye ọgwụ a maka ndị ọrịa nwere akwara ọrịa akwara na stenosis.
Azụ hypotension na-ebilite n’ahụ ndị mmadụ na-enwe ọria ahụ n’egbughị oge n’ihi nsị, nri nwere mmachi nnu, ọgbụgbọ na ọgbụgba ugboro ugboro.
Jiri na agadi
Ndị ọrịa karịa afọ 65 chọrọ iji nlezianya mee ihe nke Lysiprex, na ọnụnọ nke ọrịa na-adịghị ala ala, a na-agbakọ usoro onunu ogwu n'otu n'otu.
Inye umuaka
Emebeghi nyocha nke ulo ogwu banyere ndi oria n’agbata afọ 18; onweghi data banyere nchekwa nke ọgwụ maka ndị otu a.
Jiri n'oge ime na lactation
Onwere ihe ojoo di na nwa ovu a, okachasi n’ime onwa abuo n’abuo n’abuo nke ato. Nwanyị na-ewere mbadamba ọgwụ Lysiprex mgbe ọ mụtachara ime tụụrụ ime kwesịrị ịkwụsị ị .ụ ọgwụ. Onweghi ihe akaebe banyere enwere ike ihe ndi ogwu ahu di ngbo na ara ara. Mgbe ị na-enye nwa ara, ị isụ ọgwụ ahụ bụ ihe amachibidoro iwu n'ihi ihe egwu ọ bụla ọ nwere ike ịmetụta nwa ahụ.
Ngwa maka ọrụ ezughi oke ọrụ
Nke anabatara, ma ekwesịrị inyocha ndọta potassium.
Jiri maka ọrụ imeju na-arụ ọrụ
Enwere ike iji akara pụrụ iche. Tupu na mgbe ọgwụgwọ, ọ dị mkpa iji gosipụta ịchịkwa ọnọdụ na ọrụ nke imeju.
Do Overụbiga mmanya ókè nke Lysiprex
Dodoụbiga mmanya ókè nwere ike ime mgbe ị na-a doụ ọgwụ were 50 mg ma ọ bụ karịa. Ihe ịrịba ama: mbelata ọbara mgbali elu, oke ọkpọ akwara, ọnya nkụ, urin na iwe ya. Nsogbu CNS nwere ike: nchekasị, oke iwe.
Dodoụbiga mmanya ókè nwere ike ime mgbe ị na-a doụ ọgwụ were 50 mg ma ọ bụ karịa.
Enyemaka: na-asachapụ afọ, ịgwọ ọrịa Symptomatic, ị sorụ ọgwụ sorbents na ndị na-egbu mgbu. Site na mmụba nke ike nke ngosipụta nke ihe mgbaàmà ịdoụbiga mmanya ókè, a na-eme hemodialysis.
Mmekọrịta na ọgwụ ndị ọzọ
N'iji imeju nke sulfonylureas eme ihe, enwere nnukwu nsogbu nke hypoglycemia.
A machibidoro ndị ọrịa nwere ọrịa shuga ịmara ọgwụ ahụ n'otu oge na Lovastatin n'ihi nnukwu ihe ize ndụ nke hyperkalemia siri ike.
A machibidoro ịgwakọta Lysiprex yana ọgwụ nwere lithium. Nchikota a na-ebute mmụba nke lithium yana ihe mgbaàmà nke ịxụbiga mmanya ókè.
A machibidoro iwu ijikọ ya na Baclofen, Aliskiren, Estramustine.
Mmanya ndakọrịta
Amachibidoro ya iwu iji ngwaahịa ndị nwere ethyl n'oge ọgwụgwọ.
Analogs
Ndị nọ n'ọnọdụ Lysiprex: Liten, Lysacard, Dapril, Irumed, Diroton.
Ahịa ọgwụ na-ahapụ okwu
Ndenye ọgwụ.
Enwere m ike ịzụta na ndenye ọgwụ?
Ewezuga.
Ọnụahịa maka lisiprex
Ego ole n'ime Russia na Ukraine amabeghị. Ugbu a ọgwụ na-agba asambodo.
Ọnọdụ nchekwa maka ọgwụ
Ọnọdụ okpomọkụ ruo + 25 ° С.
Bọchị mmebi
Afọ 2
Emeputa
Irbitsky KhFZ, OJSC, Russia.
Nyocha banyere Lysiprex
Angela, 38 afọ, Moscow: "Usoro ya na Lysiprex nyeere aka itinye nna m n'ụkwụ mgbe nkụchi obi.
Kirill, 42 dị afọ, Kerch: "Ejiri m mbadamba osisi Lysiprex kwa oge ruo ọtụtụ afọ. Enwere m obi nkụchi, a nwalewo ọtụtụ ọgwụ, mana naanị ọgwụ a gosipụtara nsonaazụ kacha mma."
Sergey, 45 afọ, Kiev: "M wee ọgwụ a mgbe obi nkụchi ọ na-efe efe. Ọ gbakere ngwa ngwa, mana enwere m akụkụ ọ bụla, isi m merụrụ ya na ọbara mgbali elu. Apụghị ọgwụ n'ihi nke a, n'ihi na ọ dị irè ma nwee isi ọwụwa. nwere ike idi ya. ”
