A na-ahọrọ ọgwụ antihypertensive maka ụdị ọrịa shuga mellitus 2 n'otu n'otu, nyere mmetụta ha na arụ ọrụ nke akụrụ, mmetụta nke metabolism nke ọdụdụ abụba na carbohydrates. Ọbara mgbali ọgụ so 80% ndị na-arịa hyperglycemia. Ọrịa na - eme ka akụkụ ahụ dị n'ime ahụ gharazie ịrụ ọrụ, na - akpaghasị usoro ebumpụta ụwa nke metabolism.
Njirimara
Ọgwụ ọgwụ nke ọgwụ ndị na-arịa ọrịa shuga na-agbagha site na nsonaazụ na-adịghị mma, ngosipụta nke ọ na-akpata site na metabolism intracellular metabolism.
Nhọrọ nke ọgwụ maka ọbara mgbali elu na hyperglycemia sitere na ọnọdụ:
- Ikike kachasị arụ, obere nsonaazụ;
- Mmetụta Cardio na nephroprotective (nchebe nke obi na akụrụ);
- Enweghi mmetụta ọ bụla na ntinye nke lipids na glucose n'ọbara.
Ọgwụ ngwa ngwa
Ọ bụrụ na ị na-enwekarị nsogbu ọbara ọgbụgba na mberede, ọgwụ ọ bụla dabara adaba maka ọbara mgbali elu na ọrịa shuga kwesịrị ịdị nso.
Ọ bụrụ na ọ dị mkpa enyemaka ozugbo, iji n'aka onye mmetụta ya na-akarịghị awa 6. Ihe ndị nọ n'ọrụ bụ akụkụ nke aha azụmaahịa ọgwụ:
- Captopril;
- Nifedipine;
- Clonidine;
- Anaprilin;
- Andipal.
Ọgwụ maka ojiji sistemụ
Ọgụgụ oge dị elu karịa 130/80 mm Hg. Art. n'ihi na ndị ọrịa shuga na-arịa ọrịa microvascular, mmepe nke atherosclerosis, ọganihu nke ọrịa angiopathies na-arịa ọrịa shuga. N'okwu a, a na-atụ aro ị drugsụ ọgwụ mgbe niile, mgbe ị na-eso nri nnu na carbohydrate. Nsonaazụ ọgwụ ọgwụ nwere ike ime ka ọrịa shuga kwesiri ịdị nwayọ. Mbelata ọbara mgbali elu na-esote elu elu na-emebi ọbụna maka usoro obi nke ahụ ike.
Ihe mgbochi ACE
Maka iji nwayọọ nwayọọ na ngosipụta nke ngosipụta nke ọbara mgbali elu, a na-eji ihe mgbochi angiotensin na-emegharị enzyme (ACE), nke na-akpali njikọ nke angiotensin. Site n’ibelata mkpụkọ nke angiotensin, glands adrenal na - emepụta aldosterone dị ala, nke na - ejigide sodium na mmiri n’ime ahụ. Vasodilation na-eme, mmiri mmiri na nnu gafere, a na-egosipụta ike hypotonic.
Ihe na-arụ ọrụ na-egbochi ACE:
- Enalapril;
- Perindopril;
- Quinapril;
- Fosinopril;
- Trandolapril;
- Ramipril.
Ihe ọghọm nke inhibitors bụ ikike igbu oge iwepụ potassium na arụmọrụ oge na-egbu oge. A na-atụle mmetụta nke iji na-erughị izu abụọ ka emesịrị.
Angiotensin Receptor Blockers (ARBs)
Ha na-egbochi njikọ nke renin, nke na-akpali mgbanwe nke angiotensin, nke na-eme ka mgbidi nke arịa ọbara dị warara. A na - enye ọgwụ ARB ma ọ bụrụ na anabataghị inhibitors ACE. Usoro nke ụzọ ndu ha si dị iche iche, mana ihe mgbaru ọsọ bụ otu - iji belata nsonaazụ angiotensin na aldosterone.
A na-akpọ otu ahụ sartans na njedebe nke aha ndị na - arụ ọrụ:
- Losartan;
- Valsartan;
- Irbesartan
- Candesartan.
Diuretics
Diuretics nwere mmetụta hypotonic dị ala, ka edepụtara ya tumadi na njikọta ọgwụ na-eji ọgwụ ọbara mgbali elu ọzọ maka ọrịa shuga.
- Loop diuretics (furosemide, lasex) jikọtara nke ọma na ndị na - egbochi ACE, anaghị emetụta ọkwa shuga, lipids, ma dabara adaba maka nchịkwa oge dị mkpirikpi iji kpochapụ ọria anụ ahụ. Ojiji a na-achịkwaghị achịkwa na-eme ka ngwa ngwa kwụsịlata potassium, nke pụrụ ịkpasu mmụba na hypokalemia na ọrịa obi.
- N'ihi mmetụta diuretic dị nro, thiazide dị ka diuretics (ebepamide) anaghị akpasu nguzozi nke glucose, abụba abụba, ọkwa potassium, na anaghị emetụta arụ ọrụ nke akụrụ.
- Thiazide diuretics (hypothiazide) na usoro ọgwụgwọ kwa ụbọchị karịrị 50 mg na-enwe ike ịbawanye glucose na cholesterol. Ejiri ha jiri nlezianya mee ha obere onwonye n'ihi ọghe ọrịa akụrụ na-enwe ọfụma.
- A na-atụ aro ka ọgwụ ndị na-egbu potassium (veroshpiron) maka ụdị ọrịa shuga mellitus nke 2, yana ọrụ mkpịsị aka na-adịghị mma.
Beta igbochi
E depụtara ọtụtụ ọgwụ na-egbochi mkpali nke adrenoreceptors site na adrenaline na norepinephrine bụ isi maka ọgwụgwọ nke ischemia, cardiosclerosis, nkụchi obi. Na hyperglycemia, a na-ahọpụta mbadamba ụbụrụ ọbara mgbali elu na mmetụta vasodilating ọzọ:
- Labetalol;
- Carvedilol;
- Nebivolol.
Ndị na-emegide Calcium
Ndị na-egbochi Calcium ọwa - otu ọgwụ na-ebelata mkpụbelata ion nke sọlfọm. Zuo ike ma mụbaa mgbidi nke akwara ọbara, akwara, akwara akwara. Ekewaziri ọnọdụ na ọnọdụ dị iche iche:
- Verapamil, diltiazem. Na-emetụta ọrụ myocardium na mkpụrụ ndụ obi, belata ọnụego obi. Ejikọtara ojiji na beta-blockers.
- Nri dihydropyridine - nifedipine, verapamil, nimodipine, amlodipine. Ha na-ezu ike mgbidi sel sel dị ire ụtọ, na-eme ka ọnụọgụ obi dịkwuo elu.
Ndị na-emegide calcium anaghị egbochi carbohydrate, metabolism metabolism. Mgbe ejiri ya dị ka ọgwụ maka nrụgide, ụdị shuga 2 dị mma, mana enwere ọtụtụ contraindications. Nifedipine na contraindicated na angina pectoris, obi na akụrụ ọdịda, adabara otu enyemaka nke ọdụdọ. Amlodipine nwere ike ịkwalite ọzịza. Verapamil nwere mmetụta dị nwayọ na arụ ọrụ akụrụ, mana ọ nwere ike ibute bronchodilators.
Mmeghachi omume onwe onye
A na - agwakọta ọgwụ antihypertensive na ibe ha, ahọpụtara na-elebara ọrịa concomitant, ọgwụ ọ takenụrụ. Ọbara mgbali elu, tinyere mmebi nke ọrịa mamịrị nke metabolic metabolism, na-akpata mmeghachi omume nkeonwe dị iche iche.
Tupu ojiji, ịkwesịrị ịmụ ndepụta nke nsonaazụ ndị ọzọ, ụzọ isi kpochapụ ha.
Mgbe ị na-a takingụ, lelee usoro ọbara mgbali na-agbanwe. N'otu oge ahụ, a na-enyocha ọkwa nke hemoglobin glycated, cholesterol, triglycerides, glucose na-ebu ọnụ na mgbe ị risịrị nri. Devizọ ndị na-achọghị ka ọkwa dị mma na-achọ ọgwụ maka iji dochie ọgwụ.
