Ọnụ ọgụgụ insulin dị n'ọbara na-agbanwe agbanwe mgbe niile ụbọchị dum na nzaghachi na ntinye glucose n'ime arịa. N'ime ọrịa ụfọdụ, nsogbu na-agbagha agbagha, njikọ nke homonụ malitere ịdị iche na usoro iwu physiological. Nyocha ọbara nke insulin na-enye gị ohere ịchọpụta ihe ntụgharị a n'oge.
N'ọnọdụ ụfọdụ, dịka ọmụmaatụ, yana ọrịa metabolic, nchọpụta oge dị mkpa kachasị mkpa, ebe ọ bụ na onye ọrịa nwere ohere ịgwọ nsogbu ndị ọrịa na igbochi ọrịa shuga. Nyocha a na - enyere gị aka inyocha ọrụ nke pancreas, bụ akụkụ dị mkpa nke usoro ọmụmụ iji chọpụta ihe kpatara hypoglycemia. Na ọrịa shuga mellitus, a na-eji ego nke insulin na-ebu ọnụ n’ọbara iji gbakọọ ndepụta nnabata insulin.
Ihe kpatara inye nyocha
Insulin bu isi homonụ n’usoro dị mgbagwoju anya nke usoro nhazi nke metabolism metabolism. A na-emepụta ya na ngọngọ site na enyemaka nke mkpụrụ ndụ nke ụdị pụrụ iche - mkpụrụ ndụ beta, ha nọ n’agwaetiti Langerhans. A na-ewepụta insulin n'ime ọbara yana mmụba nke glucose na ya. Ọ na-akpali ntụgharị nke glucose n'ime anụ ahụ, n'ihi nke ọkwa ya na ọbara na-ebelata, mgbe oge ụfọdụ gasịrị, ọkwa nke hormone ahụ na-ebelata. Iji chọpụta insulin na-emepụta, a na-amịrị ọbara n’afọ na-enweghị isi, mgbe agụụ agụụ maka oge ụfọdụ. N'okwu a, ọnụọgụ ya na ndị ahụ gbasiri ike na-agbaso ụkpụrụ, na ndagide ọ bụla bụ ihe ịrịba ama nke ọgba aghara metabolism.
Ọrịa shuga na oke nrụgide ga-abụ ihe mgbe ochie
- Normalization shuga -95%
- Mwepu nke akwara mbufụt - 70%
- Mwepu nke obi ike -90%
- Bibie ọbara mgbali elu - 92%
- Mmụba na ume n'ụbọchị, na-eme ka ụra na-ehi ụra n'abalị -97%
Nnyocha e mere n’elu afọ na-adịghị n’ime ụlọ ọgwụ dịgasị iche iche nwere ike ịkpọ insulin immunoreactive insulin insal insulin, IRI. Denye ya n'ọnọdụ ndị a:
- ibu dị ukwuu ma ọ bụ mfu nke enweghị ike ịkọwa site na usoro nri;
- hypoglycemia na ndị mmadụ anaghị arịa ọgwụgwọ maka ọrịa shuga. E gosiputara ha na mmetụta nke oke agụụ, aka na-ama jijiji, iro ụra;
- ọ bụrụ na onye ọrịa ahụ nwere ọtụtụ ihe nrịba ama nke ọrịa kansa ọria: oke ibu nwere BMI> 30, atherosclerosis, cardiac ischemia, polycystic ovary;
- N'ọnọdụ doro anya, iji dokwuo anya ụdị ọrịa shuga mellitus ma ọ bụ iji họrọ usoro ọgwụgwọ kachasị ahọrọ.
Ihe nnwale insulin gosipụtara
Nnwale insulin na-enye gị ohere:
- Chọpụta akpụ, nke gụnyere sel nke nwere ike imepụta insulin. N'okwu a, a na-ahapụ homonụ ahụ n'ọbara na-enweghị atụ, n'ọtụtụ buru ibu. A na-eji nyocha ahụ ọ bụghị naanị ịchọpụta neoplasm, kamakwa iji chọpụta ihe ịga nke ọma nke ọgwụgwọ ịwa ahụ, iji chịkwaa nlọghachi ndị nwere ike.
- Iji chọpụta ike anụ ahụ nwere insulin - nguzogide insulin. N'okwu a, ị ga-emerịrị ule glucose n'out oge. Nlegide insulin bu ihe e ji mara oria oria abuo na nsogbu nke buru ya n’azu: nsogbu ibu di ala na metabolic syndrome.
- N'ọnọdụ ụdị shuga ogologo 2, nyocha ya na-egosi etu homonụ nke pancreas na-emepụta na ma onye ọrịa ahụ ga-enwe mbadamba shuga dị ala ma ọ bụ ọ bụrụ na ọ ga-edenye insulin insulin. A na-eme nyocha ahụ mgbe ọgwụgwọ nke ọrịa hyperglycemic nnukwu, mgbe a na-ebufe onye ọrịa na-arịa ọrịa shuga site na nchịkwa insulin gaa na ọgwụgwọ ọgwụgwọ.
Site na ọrịa shuga 1, a naghị eji nyocha a. Na nmalite ọrịa ahụ, ọgwụ mgbochi emepụtara ga - egbochi nkọwa ziri ezi nke nsonaazụ ya: mgbe mmalite ọgwụ, nkwadebe insulin nke yitere na homonụ nke ha. Alternativezọ kachasị mma na nke a bụ mkpuchi C-peptide. A na-ejikọ insulin ahụ n'otu oge. Ọgwụ mgbochi anaghị anabata ya, nkwadebe insulin na C-peptide anaghị enwe.
Site na dystrophy muscle, ya na ọrịa Hisenko-Cushing, ọrịa pituitary gland, yana ọrịa imeju, ọ dị mkpa iji nyochaa oge ọrụ niile akụkụ, ya mere, yana ọmụmụ ndị ọzọ, a ga-enyocha ndị ọrịa mgbe niile maka insulin.
Etu esi ewere nyocha
Obara insulin n’ime ọbara na-adabere ọ bụghị nanị n’ọkwa nke glucose, kamakwa n’ọtụtụ ihe ndị ọzọ: mmega ahụ, ọgwụ na ọbụna ọnọdụ mmetụta nke mmadụ. Iji mee ka nsonaazụ nyocha ahụ bụrụ ihe a pụrụ ịdabere na ya, ịkwadebe maka ya kwesịrị ka e lebara ya anya:
- Ruo ụbọchị 2, wepu nri nke abụba gabigara ókè. Ọ baghị uru ịnwe abụba nkịtị.
- Maka otu ụbọchị, wepụ nnukwu ibu niile, ọ bụghị naanị nke anụ ahụ, kamakwa nke mmụọ. Nchegbu n’uhuruchi nyocha ahụ bụ ihe mere iji yigharị onyinye onyinye ọbara.
- Abọchị anaghị a alcoholụ mmanya na ike, emegharịla nri ndị ị na-emebu. Nwa oge iwepụ ọgwụ niile ma ọ bụrụ na nke a anaghị ebute ahụike. Ọ bụrụ na akagbuo agaghị ekwe omume, gwa onye ọrụ ụlọ nyocha ahụ.
- 12 awa agaghị eri. Naanị mmiri a na-agbanyeghị na-enweghị gas ka a na-anabata n'oge a.
- 3 awa anaghị a smokeụ sịga.
- Nkeji iri na ise tupu i bido ọbara, nọdụ nwayọ ma ọ bụ dinaa n'ihe ndina
Oge kacha mma iji lee ule bụ 8-11 n'ụtụtụ. A na-ewere ọbara site na akwara. Iji mee ka usoro a dị mfe maka ụmụaka, ọkara elekere tupu mmalite ha kwesịrị inye otu iko mmiri ka ha .ụọ.
Ọgwụ ndị metụtara ogo insulin:
Dịkwuo | Belata |
Ọgwụ niile nwere glucose, fructose, sucrose. | Diuretics: furosemide, thiazides. |
Hormones: ọgwụ mgbochi, onuzole, glucagon, homonụ na-eto, cholecystokinin, prednisone na ndị ọzọ. | Hormones: thyrocalcitonin. |
Ọgwụ hypoglycemic ka edepụtara maka ọrịa shuga: acetohexamide, chlorpropamide, tolbutamide. | Ọgwụ Hypoglycemic: Metformin. |
Salbutamol | Phenobarbital |
Calcium gluconate | Beta igbochi |
Deckpụrụ ederede na usoro iwu
Site na nyocha ahụ, egosiri insulin n'ime ọbara na-egosipụta na ngalaba dị iche iche: mkU / ml, mU / l, pmol / l. Transfernyefe ha na ibe ya dị mfe: 1 mU / l = 1 μU / ml = 0.138 pmol / l.
Odika iwu:
Onu ogugu | Nkịtị | |
U / ml, mmanụ a /ụ / l | pmol / l | |
Childrenmụaka | 2,7-10,4 | 19,6-75,4 |
Ndị okenye nọ n’agbata afọ 60 na BMI <30 | 2,7-10,4 | 19,6-75,4 |
Ndị okenye nọ n’agbata afọ 60 na BMI> 30 | 2,7-24,9 | 19,6-180 |
Ndị okenye mgbe afọ 60 gachara | 6,0-36,0 | 43,5-261 |
Valueskpụrụ insulin nkịtị na-adabere na teknụzụ nke nyocha ahụ, yabụ na ụlọ nyocha dị iche iche ha nwere ike ịdị iche. Mgbe nnata nke nsonaazụ ahụ, ọ dị mkpa ilekwasị anya na ntinye akwụkwọ nyocha nke ụlọ nyocha ahụ nyere, ọ bụghị n'ụkpụrụ iwu.
Insulin nke dị n’elu ma ọ bụ nke nkịtị
Enweghị insulin na-eduga ná agụụ mkpụrụ ndụ yana mmụba n'ọbara glucose ọbara. Nsonaazụ ya nwere ike ịdị ntakịrị karịa ka ọ dị na ọrịa ọrịa pituitary na hypothalamus, ya na nrụgide na ike ọgwụgwụ, ya na mgbali anụ ahụ ogologo oge yana enweghị carbohydrates, yana ọrịa na-efe efe ma ọ na-efe ha ozugbo.
Mbelata dị ukwuu na insulin na-egosi mmalite nke ụdị ọrịa shuga 1 ma ọ bụ mmebi nke ọrụ pancreatic na ndị ọrịa nwere ụdị shuga 2. Ọrịa pancreatitis na-akpata nnukwu ọrịa na pancreatic necrosis nwekwara ike ịbụ ihe na-akpata ya.
Ọnụọgụ insulin dị n'ọbara na-egosi nsogbu ndị a:
- Mellitus na-arịa insulin na-abụghị insulin. Ka ọrịa a na-aga n’ihu, ọkwa insulin ga-ebelata, glucose ọbara ga-amụba.
- Insulinoma bụ akpụ nwere ike imepụta na izochi insulin n’onwe ya. N'otu oge ahụ, enweghị njikọ n'etiti oriri shuga na njikọ insulin, ya mere hypoglycemia bụ ihe ịrịba ama dị mkpa nke insulinoma.
- Nnukwu insulin na-eguzogide. Nke a bụ ọnọdụ nke ike ahụ ịnabata insulin na-ebelata. N'ihi nke a, shuga anaghị ahapu n'ọbara, a na-amanye pancreas ịkwalite njikọ homonụ. Nlegide insulin bụ ihe ịrịba ama nke ọrịa metabolism, gụnyere ụdị ọrịa shuga 2. Ya na oke ibu nwere njikọ chiri anya: ọ na - eto ka ị na- ahụ ibu, na insulin buru ibu, n’aka nke ya, na - enyere aka ibugharị abụba ọhụrụ.
- Ọrịa metụtara oke ịba ụba nke homonụ insulin antagonist: syndrome Hisenko-Cushing ma ọ bụ acromegaly. Na acromegaly, adenohypophysis na-ewepụta oke ibu nke hormone ibu. Ọrịa Hisenko-Cushing na mgbakwunye ụba nke homonụ nke eriri afọ adrenal. Homonụ ndị a na - ebelata ọrụ nke insulin, yabụ na - eme ka njikọ ya ka mma.
- Ọrịa metabolic na akụrụngwa nke galactose na fructose.
Restgha ọgwụ insulin karịa nke na-ezighi ezi na nkwadebe na-ezighi ezi maka nyocha na nhazi nke ụfọdụ ọgwụ.
Ọnụahịa
Ọnụ ego nke nyocha na laborat laboratia sitere na 400 ruo 600 rubles. A na-akwụ ụgwọ obara iche iche; ọnụ ahịa ya ruru 150 rubles. Ọmụmụ ihe ga-amalite ozugbo, yabụ, ụbọchị ọrụ ị ga - eso nweta nsonaazụ ya.
More na isiokwu:
>> Nnwale ọbara maka shuga - maka gịnị, otu esi ewere ma ghọta nsonaazụ ya.