Cholesterol dị elu na-arịa ọrịa shuga bụ ihe ịrịba ama na-ezighi ezi maka onye ọrịa.
Nke a bụ n'ihi eziokwu na na mmụba nke ọkwa cholesterol (na akwụkwọ ndị America "cholesterol"), a na-emechi ajọ ihe ojoo nke ọrịa obi.
Okwa nke lipids di elu n’ime obara, n’etu nnukwu ihe ibute oria akwara, nke, n’aka nke ya, na-abawanye ohere nke ibute ọrịa shuga mellitus.
N'akụkụ a, ọ dị oke mkpa ịlele nchịkọta nke cholesterol na ọrịa shuga.
E nwere ụdị cholesterol abụọ dị n'ụdị, dị ka ogo ya si dị, yana protein ndi njem:
- lipoproteins dị ala na obere ala (LDL, VLDL) bụ "ihe na-emerụ ahụ" lipids liherogenic ma na-emebi ahụ;
- Ngwakọta mmanụ ala dị elu ma dị oke mma (HDL, HDL), na ntụle, nwere ihe mgbochi antiatherogenic ma gbochie ihe ize ndụ nke ibute atherosclerosis nke arịa ọbara.
A na-amata ndị ọrịa shuga site na mmụba na ọkwa LDL na mbelata nke ọkwa HDL ma e jiri ya tụnyere ọnụọgụ mmadụ nke ndị mmadụ nwere ahụike. Mmụba na ọkwa LDL na ihe ngosi TAG na-ebu ihe ọghọm nke ịmalite ajọ ọrịa vaskụla. Metabolism na-arịa ọrịa glucose na-eme ka mmadụ ghara ịdị nkọ n’etiti iberibe lipoproteins. Mmụba nke egbugbere ọnụ ọbara na-arịa ọrịa shuga na-esonyere usoro ndị a.
- Ọbara nke onye ọrịa na-arịa ọrịa shuga mellitus ekwupụtala adhesion na nkwenye nke lipids n'efu.
- N'ihi ọrịa dị ogologo, vaskụla endothelium bụ ihe na-emebi emebi ma na-enwekwa ike inwe nrụpụta.
- Mmụba na glucose na-eduga n'ịba ụba n'oge mgbasa nke lipoproteins atherogenic na ọbara.
- Ogwu dị ala nke na-egbochi ọgwụ atherogenic na-abawanye ihe ize ndụ nke nnukwu ọrịa obi.
- Nweta oghere ọnya na-arịa ya na-akarị ọrịa shuga.
- Nchikota nke uzo abuo a na - akwalite uto nke obula.
Na njikọta usoro mmetụta dị n’elu, ekwesịrị ilekọta serum cholesterol n’ime ọrịa shuga siri ike mgbe niile. Ekwesịrị ịdebanye aha onye ọrịa ahụ na endocrinologist na therapist.
Uru cholesterol dị na ọrịa shuga
Dika ihe omumu nke ulo ogwu di nso, cholesterol di elu na oria mamellitus na ebute oganihu nke oria a ma bulie ohere nke oria obi.
N'agbanyeghị ogo ọrịa a jikọtara ọnụ, ọ na-anabata ọgwụgwọ nke ọma.
Monitoringnyocha mgbe niile na-ebu ọnụ glycemia, ọbara mgbali na itinye uche nke lipoprotein na-enyere aka ịme ka ọnọdụ onye ọrịa dị ka ọ dị.
Na ọrịa shuga nke ụdị mbụ (nke afọ) yana ileba anya na ọkwa nke glycemia, a naghị achọpụta mmụba nke profaịlụ lipid. Mana maka ndị ọrịa nwere ọrịa angiopathy na ọrịa shuga 2, ọnọdụ ahụ dị iche.
Nnyocha ọbara dị ogologo maka ọrịa lipids na ụdị ọrịa shuga 2 bụ:
- cholesterol HDL belatara;
- obere HDL;
- mmụba na ọkwa LDL;
- eto elu nke VLDL;
- mmụba nke cholesterol zuru ezu;
- ọkwa nke TAG.
Changesdị mgbanwe ndị a na profaịlụ lipid na-eduga na nkwụnye nke lipoproteins atherogenic na mgbidi nke endothelium ma na-eduga na mgbochi nke akwara akwara. Mkpụrụ obere ọgwụ mgbochi antiatherogenic enweghị ike ịnagide ọganihu nke ọnya ọnya ọnya akwara ozi. Triglycerides na-emetụtakwa usoro nke metabolic transformation nke lipids. N'ihi mkpochasị arịa ahụ, hypoxia nke anụ ahụ na-enye ọbara na-amalite.
Na erighị nri na-adịghị ala ala na ụkọ oxygen, akwara dystrophy na-amalite, na nnukwu - necrosis. Onye ọrịa mamịrị nwere cholesterol dị elu nwere ohere nke ịnweta nnukwu ọrịa myocardial infarction ma ọ bụ ụbụrụ ụbụrụ n'ọdịnihu dị nso.
Na mgbakwunye, micro-arịa na macroangiopathy na-aga n'ihu na ntinye nke usoro atherosclerotic.
Mmekọrịta nke insulin na cholesterol n'ime ọbara
Ruo ugbu a, a na-eme nnyocha banyere mmetụta insulin na-aba ụba na mmiri biochemistry, gụnyere ogo ndụ. Increasedba ụba nke insulin homonụ n'ime ọbara na-eduga n'ịbawanye ụba nke liherogenic lipids yana mbelata mkpo antipherogenic lipids. Na mgbakwunye, ụkpụrụ cholesterol dị elu bụ njirimara nke ndị ọrịa nwere nnukwu ọgwụ insulin resistance syndrome.
Emega ahụ na-eme ka ọ belata ogo cholesterol. Eziokwu a dị mkpa maka oke ibu ma ọ bụ oke ibu. Maka ndị ọrịa nwere ụdị ọrịa shuga mbụ, ilekọta glycemia nwere ike belata cholesterol n'otu oge.
Site na nlezianya nke ọgụgụ ihe glucose, a na-ahụta ihe gbasara ọkwa cholesterol ọbara. O di nwute, site na usoro ọgwụgwọ hypoglycemic na-adịghị mma na ụdị ọrịa shuga mbụ, hyperlipidemia siri ike na-amalite.
Nke a na - ebute ihe egwu dị elu nke atherosclerosis n’otu ndị ọrịa. N'ihe dị ka ndị ọrịa niile nwere ọrịa mellitus nke ọrịa shuga, a na-ahụta mbibi akwara na-emebi emebi. Mmebi ndị na-egosi na endothelium na-achịkọta ụmụ irighiri mmiri cholesterol.
Nke a na - ebute uto ngwa ngwa nke ihe a na - akpọ andherogenic ma na - ebulikwa ohere nke thrombosis, ihe mgbochi nke lumen nke akwara ndị mmadụ na mmepe nke nnukwu ọrịa akwara.
Methodszọ ndị bụ ọgwụgwọ
Suzọ kachasị mma iji belata cholesterol ọbara bụ site na mgbanwe obibi ndụ.
Onye ọrịa ahụ kwesịrị ibu ụzọ gakwuru onye ọkachamara ahụike maka ndụmọdụ.
Ọ dịkwa mkpa ịgbasochi ọgwụ anya, were ha nke ọma dịka dọkịta nyere gị.
Ihe ndị a tụrụ aro maka ị fatụ abụba ga-eme ka ọrịa ahụ na ndụ mmadụ dịkwuo mma.
- Iri oke abụba juru afọ na carbohydrates ngwa ngwa nwere ike ime ka ị nweta cholesterol n'ime ọbara. Ojiji ha kwesịrị inwe oke.
- Enweghị mkpa iwepụ abụba kpamkpam na nri.
- Abụba kachasị abụba na nri bụ abụba polyunsaturated. Ndi nnochite anya nke Omega-3 na Omega-6 fatty acids. A na-ahụkarị acid omega na mmanụ ihe oriri na azụ.
Folkzọ ndị mmadụ pụtara ìhè iji kpochapụ shuga n’ọbara shuga ma kwalite cholesterol - ụdị ndụ dị mma, ụdị na ụdị nri.
Isi ọgwụgwọ hypercholesterolemia bụ ojiji nke statins. Otu a ọgwụ nwere akpọ antiatherogenic mmetụta. Ọrịa shuga 2dị nke abụọ na cholesterol dị elu bụ ọrịa, n'ọtụtụ oge, concomitant.
A ga-ejikọrịrị usoro ndị a na-eji ọgwụ ọgwụ na mgbanwe ụzọ ndụ, mgbanwe na nri na mmụba na ihe ọkụkụ na abụba ahụike, yana mmega ahụ nkịtị. Approachzọ a ga-esi gwọọ ya ọrịa ga-ebelata ọghọm nnukwu ọrịa obi. Ọgwụgwọ ahụ na-esitekwa na profaịlụ egbugbere ọnụ ya, ahụike nke onye ọrịa, njiri afọ yana ọnụnọ nke ihe ọghọm.
A kọwara mmekọrịta dị n'etiti ọrịa shuga na atherosclerosis na vidiyo n'isiokwu a.
