Mikardis Plus na-ezo aka ọgwụ ọgwụ antihypertensive. Ọgwụ nwere ọgwụ jikọtara ọnụ nke abụọ na - arụ ọrụ - telmisartan na diuretic. Site na ngwakọta kemịkal a, enwere mmetụta hypotensive, na-adigide ruo awa 6-12. Nchikota hydrochlorothiazide na telmisartan na-enye gị ohere ịme ọbara mgbali elu.
ATX
C09DA07.
Mikardis Plus na-ezo aka ọgwụ ọgwụ antihypertensive.
Ha weputara udi ya na ihe mebere ya
A na-eme ọgwụ ahụ n'ụdị mbadamba ụrọ, nke nwere ogige 2 na-arụ ọrụ - telmisartan na hydrochlorothiazide.
| Njikọ Ọrụ | Nchikota usoro onunu ogwu, mg | ||
| Telmisartan | 80 | 80 | 40 |
| Diuretic | 12,5 | 25 | 12,5 |
| Ọgwụ agba | Uhie na-acha ọbara ọbara na pink | Agba odo na nsị nke edo edo | Pink |
Dika ihe ndi ozo ndi n’eme ka osiso di elu na izuzu, anyi bu:
- ọka ọka;
- mmiri ara ehi shuga;
- microcrystalline cellulose;
- sodium hydroxide;
- ihe eji agba aja ocha;
- povidone;
- sorbitol;
- meglumine.
Mbadamba na-eji oval nwere biconvex elu. A naghị emepụta ihe na - egbochi ọgwụ n'ụdị ịgba, gel, ma ọ bụ usoro parenteral.
A na-eme ọgwụ ahụ n'ụdị mbadamba ụrọ, nke nwere ogige 2 na-arụ ọrụ - telmisartan na hydrochlorothiazide.
Omume ọgwụ
Telmisartan nwere mmetụta antihypertensive n'ihi na-ejikọ ya na ndị na-anabata angiotensin II. Site na nguzobe nke uzo di otua, ihe ndi n’aru n’enye nsogbu nke ensots nke vasoconstrictor ma belata ntinye nke aldosterone n’ime obara. Angiotensin II enweghị ike ibute bradykinin, n'ihi na telmisartan na-egbochi ya. Ya mere, nchịkọta bradykinin na - aga n'ihu - vasodilator na - eme ka lumen dị n'ọbara.
Mmetụta vasodilating na-eme ka hydrochlorothiazide dịkwuo elu n'ihi nsonaazụ ahụ. Turezide diuretic na-enyere aka belata ọbara mgbali elu na oke ọbara ọgbụgba. Site n'iji ogologo oge, hydrochlorothiazide na-ebelata ihe ize ndụ nke ịmalite ọrịa obi na onwu site na ọrịa ndị a.
A na-enweta ihe ọgwụgwọ kachasị elu n'ime awa 3.5-4.
Ihe ngosi ọbara ọbara na-akwụsi ike ruo awa 6-12.
Mlọ ọgwụ
Mgbe ejiri ya, enzymes eriri afọ mebiri mbadamba ihe.
Mgbe ahapụpụtara ya, akụkụ arụ ọrụ nke ọgwụ Mikardis Plus na-abanye ngwa ngwa na mgbidi nke obere eriri afọ.
Mgbe ahapụpụtara ya, mmiri na-arụ ọrụ na-abanye n’ime mgbidi nke obere eriri afọ wee banye n’ọbara. N'ime usoro sistemụ, telmisartan na hydrochlorothiazide na-abanye n'ọtụtụ kachasị na nkeji 30-90. Bioavailability nke ụdị nke abụọ nke angiotensin receagonor antagonist ruru 50%, hydrochlorothiazide n'ime 60%. A na-agbanwe ihe ndị na-arụ ọrụ na hepatocytes.
Ọkara ọkara bụ ihe dịka awa 6. Telmisartan na-ahapụ ahụ ya n'ụdị ngwaahịa ngwaahịa anaghị emebi emebi site na sistemụ byụkụ na 60-70%. Hydrochlorothiazide na-agbanwegharịghị na mmamịrị site na 95%.
Ihe ngosi maka ojiji
Ọgwụ dị mkpa iji belata ọbara mgbali elu na arụmọrụ nke telmirsartan ọgwụgwọ dị ka monotherapy.
Ihe ngbanwe
Ebumnuche ọgwụ a abụghị maka ọgwụgwọ nke ndị ọrịa nwere nnabata onwe onye na akụkụ ndị ọzọ nọ n'ọrụ na Mikardis Plus. Usoro ndị a na - esochi usoro a na - ababakwa contraindication maka iji:
- ihe mgbochi nke bile nwere otutu cholestasis;
- nsogbu nke imeju;
- akara akụrụ arụmọrụ;
- ọrịa shuga siri ike;
- ịba ụba nke calcium na protein dị ala n’ime ahụ;
- dị nke ekweghị eketa na galactose, fructose, lactose.
Amachibidoro ọgwụ a iji mee ihe na ndị ọrịa nwere ọdịda akụrụ na ọrịa shuga ya na iji ya mee ihe yiri nke Aliskiren.
Etu ị ga-esi
Site na oria ogwu di omimi rue n’iru, Mikardis na ewere oge 1 n’otu oge n’enweghi ata. Iri nri ugbu a anaghị emetụta ọgwụ ọgwụ Mikardis.
Site na oria ogwu di omimi rue n’iru, Mikardis na ewere oge 1 n’otu oge n’enweghi ata.
Maka ndi okenye
Odi onodu ubochi n’eme ka onodu otu pateeji nke nwere 80 mg nke telmisartan na 12.5 mg nke hydrochlorothiazide. Ọ bụrụ na mmetụta hypotensive ezughi oke, mana na ntachi obi dị mma, ịkwesịrị ị tabletsụ mbadamba nwere 80 mg nke telmisartan na 25 mg nke hydrochlorothiazide.
A na-ahụkarị mmetụta hypotensive ka ọnwa 1-2 gachara mmalite ọgwụgwọ ọgwụgwọ.
Ndị ọrịa nwere ọbara mgbali elu kwesịrị iwere mbadamba 2 kwa ụbọchị. N'okwu a, usoro ọgwụ hydrochlorothiazide ka dọkịta debere ya dabere na data ụlọ ọgwụ nke onye ọrịa.
Oge ntinye Mikardis Plus maka ụmụaka
A machibidoro ọgwụ a ọgwụ ruo mgbe ọ gbara afọ 18 n'ihi ụkọ ihe ọmụma banyere nsonaazụ ihe ndị dị ike na mmepe mmadụ na ụlọ akwụkwọ ọta akara na oge uto.
A machibidoro ọgwụ Mikardis Plus ọgwụ maka ihe ruru afọ 18.
Na-a drugụ ọgwụ maka ọrịa shuga
Ndị ọrịa na-arịa ọrịa shuga kwesịrị ịdị na-enyocha ọkwa glucose ọbara ha mgbe niile. N'oge ọgwụgwọ na Mikardis, enwere ihe ize ndụ nke hypoglycemia n'ihi nsonaazụ nke hydrochlorothiazide.
Nsonaazụ
A na-egosipụta mmetụta na-adịghị mma n'ihi usoro a họọrọ nke ọma ma ejiri ya pụta n'ọtụtụ ebe site na nsogbu izugbe.
Ọkpụkpụ afọ
E nwere ihe ọghọm nke imepụta ọnya ọnya afọ nke afọ na gastritis. Patientsfọdụ ndị ọrịa na-enwe ihe mgbu, afọ ntachi, afọ ọsịsa, na ọgbụgbọ.
Ahụhụ Hematopoietic
A na-eme ka ọkwa nke ihe guzobere na plasma ọbara.
Sistemụ akwara Central
Site na nkụda mmụọ nke sistemụ akwara na mmepe nke nsogbu uche mmadụ, ihe omume ahụ gbanwere - ọnọdụ ịda mba, echiche nke ụjọ na-apụta.
Dizziness, isi ọwụwa, paresthesia, adịghị ike n'ozuzu, nsogbu ịrahụ ụra nwere ike ịda.
Site na usoro urinary
N'ime ndị ọrịa nwere nsogbu mmamịrị nwere nsogbu (yana ọrịa hyperplasia benign prostate, prostatitis), njigide mmamịrị na ndọtị ga-ekwe omume. N'ọnọdụ ndị a na-adịghị ahụkebe, enwere mmụba na mkpokọta plasma nke uric acid.
Site na sistem iku ume
Na agbasa ndabere nke angioedema, ọdịdị nke ihe mgbochi ikuku, ọdịdị nke bronchospasm enwere ike.
Site na usoro akwara
A na-amata mmeghachi omume na-adịghị mma na akwara ikiri olu site n'ọdịdị cramps na mọzụlụ nwa ehi, mgbu na nkwonkwo na akwara, ọkachasị na azụ.
Ahụhụ
N'ime usoro ire azụmaahịa, edekọla banyere ọdịdị nke lupus system nke etrythematosus, angioedema, na mmeghachi omume anụ ahụ.
Ntụziaka pụrụ iche
Ọgwụ nwere mmetụta vasodilating na-adịgide. Site na olu dị ala nke na-eme ka ọbara na-erugharị (BCC), nrụgide dị n'ọbara ga-ebelata, ebe ọ bụ na mmiri na olu nke iweta ọbara agaghị ezuru maka mgbasa ozi nkịtị. N'ihi ohere ịbawanye hypotension, ọrịa nwere ntakịrị nri, yana afọ ọsịsa na vomiting, mgbe ị na - a takingụ ya tupu ha ewere Mikardis Plus, ọ dị mkpa iji weghachi BCC.
N'ọnọdụ ụfọdụ, ọgwụ ahụ na-akpata mmeghachi omume anụ ahụ.
Iwere onye na-ahụ maka ọrịa nwere ike iduga mmepe nke ihe mberede cerebrovaskụla ma ọ bụ nkụchi obi na ndị ọrịa nwere ischemia obi.
Hydrochlorothiazide nwere ike ịkpasu ụdị ọrịa myopathy nnukwu ma ọ bụ ọdịdị glaucoma akụkụ. Ihe mgbaàmà izizi nke usoro ịrịa ọrịa bụ ihe mgbu dị n ’anya, nke anaghị apụ ogologo oge. Ọ bụrụ n ’ị na-enwe ihe mgbu yana ịbelata nhụsianya anya, ị ga-akwụsị ozugbo were Mikardis Plus.
Mmanya ndakọrịta
N'oge ọgwụgwọ antihypertensive, a naghị atụ aro ị drinkụ ihe ọholicụ alcoụ na-egbu egbu.
Mmanya ethyl nwere ike imebi mmetụta antihypertensive, welie mmetụta nke hydrochlorothiazide ma mee ka spasm nke endothelium vaskụla na arịa ime ala.
Mmetụta ikike ịchịkwa usoro
Ọgwụ a anaghị emetụta arụmọrụ sistemụ akwara yana ịrụ ọrụ ọfụma. N'otu oge ahụ, ọ dị mkpa iji lelee anya mgbe ị na-arụ ọrụ na usoro mgbagwoju anya yana mgbe ị na-anya ụgbọ ala, n'ihi na ọ ga-ekwe omume ida mmụọ, ọdịdị nke nsonaazụ ndị ọzọ (iro ụra, nkụda mmụọ). Mmetụta na-adịghị mma nwere ike ibute ịta ụta na ọsọ nke mmeghachi omume psychomotor dị mkpa maka ịnya ụgbọ ala.
Jiri n'oge ime na lactation
Prohibitedmụ nwanyị n’oge ime machibidoro ị takingụ Mikardis n’ihi ọghọm o nwere ike ibute nsogbu nwa ebu n’afọ.
N'ime usoro nke ẹmbrayo, ịtọlite usoro akwara obi na sistem.
Mgbe ị na-anara ọgwụgwọ ọgwụ, ọ dị mkpa ịkwụsị ị breastụ ara.
Mgbe ị na-anara ọgwụgwọ ọgwụ, Mikardis Plus ga-akwụsị ịfeụ ara.
Dodoụbiga ya ókè
N'iji otu usoro onunu ogwu di elu karie aro achoro, ihe omuma nke ihe iriba ama riri oke. Mgbaàmà gụnyere:
- wedata ọbara mgbali elu;
- mụbaa ma ọ bụ belata obi obi;
- ọgbụgbọ
- ọgba aghara nke nsụhọ;
- iro ụra
N'ụfọdụ, mmetụta diuretic na-amalite. N'ihi oke mmiri nke mmiri na-erugharị, ahụ gị na-akpọnwụ akpọnwụ, ogo electrolytes na-ebelata. Ọdịdị hypoglycemia na-eme ka ihe mgbu ma ọ bụ kwalite arrhythmia.
N'ihe banyere ịdoụbiga mmanya ókè, onye ọrịa chọrọ ụlọ ọgwụ. N'ọnọdụ ọnọdụ, a na-elebara ọgwụgwọ anya iwepu ihe mgbaàmà na-adịghị mma na ịme ka usoro mmiri elektrik.
Mmekọrịta na ọgwụ ndị ọzọ
Site na iji Mikardis n'otu oge ya na ndị nwere lithium, mmụba mgbanwe enwere ike itinye uche n'ọtụtụ lithium.
N'akụkụ a, mwepụ nke akụrụngwa lithium na-egbu ma na-egbu egbu, ọ bụ ya mere na-atụghị ya aro ka e nye ya ọgwụ na lithium yana ọgwụ na-akwụ ụgwọ. A na-ahụ ọnọdụ yiri nke ahụ na nkwadebe potassium.
Ọgwụ ndị na -ebelata ọdịnaya potassium na plasma ọbara na-enye aka na mmepe nke hypokalemia. Site na nhazi oge ha na Mikardis, ọ dị mkpa ịchịkwa ọkwa nke potassium n'ime ahụ.
Ọgwụ ndị na-alụso ọrịa ọgụ ọgụ (NSAIDs) nwere ike ịkpalite mmepe nke akpịrị, nke mere ndị mmadụ gaferela afọ iri ise ji nọrọ n'ihe ize ndụ nke ọdịda akụrụ. NSAIDs na-ebelata ọgwụgwọ ọgwụgwọ diuretics na ọgwụ antihypertensive.
Ọgwụ Anticholinergic yana Mikardis Plus belata motility nke mọzụlụ eriri afọ.
Ngwakọta nke barbituric acid na antipsychotics kpalitere mmepe nke hypolatets orthostatic na mwepu mmụọ na-esote.
Metformin na-abawanye n'ihe ize ndụ nke lactic acidosis mgbe ị na-emekọrịta hydrochlorothiazide.
Ọgwụ ndị ọzọ antihypertensive na Mikardis bụ synergistic - a na-akwalite mmetụta hypotensive ọtụtụ oge dabere na njirimara onye ọrịa ahụ.
Iri cholesterol na-ebelata ike iwebata hydrochlorothiazide. Ọgwụ Anticholinergic na-abawanye ihe bioav adị nke ọrịa dihiaiti thiazide, n'ihi nke a na-enwe mbelata nke peristalsis nke akwara dị mma nke eriri afọ.
Emeputa
Beringer Ingelheim Ellas A.E., Koropi, Greece.
Mikardis Plus Analogs
Na enweghị mmetụta dị egwu, enwere ike dochie anya Mikardis na otu nke analogues:
- Ndị a;
- Ochichi;
- Lozap Plus;
- Telmisartan;
- Telmisartan Richter;
- Telmista.
Ahịa ọgwụ na-ahapụ okwu
Enwere ike ịzụta ọgwụ ọgwụ mgbochi siri ike site na ndenye ọgwụ.
Ọnụahịa
Ọnụ ego nke mbadamba dịgasị iche site na 1074 ruo 1100 rubles.
Ọnọdụ nchekwa Mikardis Plus
Ọ na-atụ aro ka echekwa onye na - ahụ maka ọgwụ mgbochi ebe a na - anọpụ iche site na radieshon ultraviolet na okpomọkụ nke + 8 ... + 25 Celsius.
Bọchị mmebi
Afọ 3
Nyocha banyere Mikardis Plus
Dabere na ndị ọkà mmụta obi na ndị ọrịa, Mikardis bụ ngwá ọrụ dị mma n'ọgụ megide ọbara mgbali elu.
Ndi Okacha Cardio
Elena Bolshakova, dibia bekee, Moscow
Emere m ọmụmụ ihe dị ka akụkụ nke akwụkwọ nyocha na nsonaazụ nke ọgwụ, ya mere enwere m ike iji obi ike kwuo banyere ịdị irè nke Mikardis. Ọgwụ na-enyere aka ime ka nrụgide etiti ọdụ dị belata ma belata mgbasa nke ebili mmiri, nke na-akpalite mmepe nke ọrịa obi. Ọgwụ a dị irè ma ndị na-eto eto ma ndị agadi. Nsonaazụ ndị ga-achọ ọgwụgwọ ọzọ, na amabeghị. Ọgwụ anaghị emetụta ịta.
Sergey Mukhin, dibia bekee, Tomsk
Echere m na ọgwụ a bụ ngwá ọrụ dị irè iji belata ọbara mgbali elu. Mgbe ewere ya otu ugboro n’ụbọchị, ọgwụgwọ ahụ na-adịgide otu ụbọchị. Ọnụahịa ahụ dị elu. Ndepụta nke contraindications buru ibu. Mana ọgwụ dị irè maka ụdị ọrịa shuga 2, ọrịa obi na -akpata. Amachibidoro iji ndị ọrịa ọrịa obi na-adịghị ala ala. A na-ahụtakarị ihe nfụkasị ahụ na omume m.
Enwere ike dochie Mikardis Plus na Pritor, nke edobere ya na ebe dịpụrụ iche na radieshon ultraviolet na okpomọkụ nke + 8 ... + 25 Celsius.
Ndị ọrịa
Dmitry Gavriilov, 27 afọ, Vladivostok
Ọbara mgbali elu bidoro, n'ihi nke n'uhuruchi ahụ ike adịghị mma, enweghị ikuku mgbe niile, na arrhythmia bidoro. Ndị dọkịta depụtara mbadamba Mikardis. Ọgwụ malitere ime ihe n’ụbọchị mbụ. Mgbe awa atọ gachara mbadamba nkume ndị ahụ, nsogbu ahụ kwụsịrị maka awa 20 na-esote. Ọ dị mkpa ị takeụ ọgwụ ndị ọzọ ga - enyere aka ịnọgide na-enwe mmetụta a. Ana m akwado ịkpọ dọkịta gị maka ọgwụ nri ndị ọzọ ọgwụ nje ndị ọzọ.
Alexandra Matveeva, onye gbara afọ 45, St. Petersburg
O nwere mgbali ọbara mgbe a wasịrị ya aka na akwara thyroid. Ọkpụkpụ akwara ahụ nyere mbadamba MikardisPlus mbadamba ọrụ ogologo oge. Ọ masịrị m ọgwụ ahụ, ọ na-eji nwayọ wedata ọbara ọgbụgba. Nsonaazụ nke ọgwụ anaghị emetụta ahụ ma ọ dịghị akpata nfụkasị, mmeghachi omume anaphylactic. Nrụgide ahụ erutela 130/80 ma nọgide na ọkwa a. Ana m adụ gị ọdụ ka ị were izu izu abụọ tupu ị takingụọ ọgwụ.
