Ọgwụ antihypertensive na ọgwụ diuretic na ihe abụọ dị n’ime ya. Emere ya maka ọgwụgwọ nke ndị ọrịa nwere usoro nkwonkwo egosipụtara nke mgbali elu akwara.
International Nonproprietary Aha
Ramipril + hydrochlorothiazide.
Aha mba ụwa na-abụghị nke aka bụ Hartil-D bụ Ramipril + hydrochlorothiazide.
Ata
ATX Koodu C09BA05
Ha weputara udi ya na ihe mebere ya
Ọgwụ a dị n'ụdị nke mbadamba ụdị edo edo. Edere ihe odide n’otu akụkụ, dabere na usoro onunu ogwu:
- 2,5 mg - n'otu akụkụ yana 12.5 mg - n'akụkụ nke ọzọ, n'akụkụ abụọ nke ihe ndị kewara ekewa;
- 5 mg na otu akụkụ na 25 mg n'akụkụ nke ọzọ, n'akụkụ abụọ nke ihe ize ndụ.
Ke kiet ke otu kaadiboodu nwere ike ịbụ blister 2 nke 14 iberibe.
Ngwakọta nke mbadamba nkume ahụ nwere ihe abụọ na-arụ ọrụ:
- ramipril na usoro onunu ogwu nke 2.5 ma obu 5 mg;
- hydrochlorothiazide - 12.5 mg ma ọ bụ 25 mg, n'otu n'otu.
Agbakwunyere - ihe siri ike, ihe di iche iche na ihe ndi ozo yiri ya.
Omume ọgwụ
Ramipril bụ ihe eji eme ka ọnụọgụ ọbara. Ọ na - agbatu ọrụ nke ACE inhibitor (exopeptidase), na - ebute nsonaazụ hypotensive: ngụkọta nguzogide arịa ụsọ na pulmonary capillaries na - adị obere, ihe gbasara obi na - abawanye na iguzogide nrụgide.
Na mgbakwunye, ihe na-arụ ọrụ na-eme ka ọbara na-erugharị na myocardium ma na-egbochi mgbasa nke necrotization na nkụchi obi, na-ebelata ohere nke arrhythmias na ịdị njọ nke obi obi.
Ihe nke abụọ na - arụ ọrụ - hydrochlorothiazide - na - ezo aka thiazides ya na njiri nke diuretic.
Na-agbanwe nguzozi sodium ma belata nzaghachi nye norepinephrine na ụdị II angiotensin.
Site n'enyemaka nke Hartil-D, a na-ebelata nrụgide dị na ọdụ ụgbọ okporo ígwè.
N'ime ndị ọrịa nwere ọrịa shuga na nephropathy site n'enyemaka nke ọgwụ a, nrụgide dị na veinal portal na-ebelata ma mmepe nke ọdịda akwara.
Ọgwụ na-amalite ihe dị ka otu elekere mgbe nlekọta nchịkwa ahụ na-adịgide ihe dị ka otu ụbọchị.
Mlọ ọgwụ
Ntinye nke ihe mmerụ ahụ na - eme ngwa ngwa, mgbe otu elekere gachara ruru (50-60%). Ọ na - eme ka metabolites dị ike na arụ ọrụ nke na - ejikọ protein protein plasma ọbara.
A na-etinye diuretic ahụ ngwa ngwa ngwa ngwa ramipril, akụrụ na-ekesa ma wepụta 90% site na akụrụ n'ụdị mbụ ha.
Emere ya ka ọ fụkọta ya na mmamịrị na feces.
N'ihe banyere ọrụ akụrụ na-emebi emebi, mkpo nke ramiprilat (metabolite na-arụ ọrụ) na-abawanye, ma a bụrụ na nsogbu imeju, ramipril.
Ihe ngosi maka ojiji
A na - egosi Hartil D maka ọbara mgbali elu, ma ejiri ya maka ọrịa ụfọdụ nke obi na akụrụ.
Edere ya maka ọgwụgwọ nke ọrịa ndị a:
- ọrịa obi na-adịghị ala ala;
- ọbara mgbali;
- ọrịa shuga ma ọ bụ ọrịa nephropathy;
- IHD iji belata ohere ọrịa infịction myocardial ma ọ bụ ọbara ọgbụgba ụbụrụ (strok).
Ngosiputa maka iji bu ihe kwesiri ntinye aka na ọgwụgwọ diuretics ya na ndi mmeru aru.
Ihe ngbanwe
Ejila ọgwụ ma ọ bụrụ:
- hyperrections na akụkụ ọ bụla nke ọgwụ ma ọ bụ ihe ndị sitere na otu sulfonamide otu;
- ọnụnọ edema nke akwa dị omimi nke anụ ahụ nke anụ ahụ na nke anụ ahụ dị na anamnesis;
- imechi akwara akwara hepatic na ihe isi ike na obbara igba ma obu nchikota akwara nke otu akwara;
- cholestasis;
- hypotension akwara;
- ruo afọ 18, n'ihi enweghị data na nsonaazụ ahụ ụmụaka
- mgbe adrenal cortex zoro ezo karịa aldosterone karịa ka a na-achọkarị;
- gbasara akwara.
Achọghị ịgwọ ndị nwanyị ọgwụgwọ n’oge ime na mgbe a na-enye nwa ara.
Jiri nlezianya
Site na ezigbo dọkịta na nlekọta nke dọkịta, a na-enye ya ọgwụ maka ọrịa aldosteronism, nnagide ma ọ bụ malabsorption nke glucose ma ọ bụ galactose, n'oge ịba ọcha n'anya,
Uzo esi ewere Hartil D
Ọ bụ dọkịta nyere usoro ọgwụgwọ ahụ ka ọ dị n ’usoro nke ọ bụla.
Mbadamba ụrọ na-ewerekarị ụtụtụ, na-enweghị ata ata. N'otu oge ahụ, ha na-eri nnukwu mmiri. Ejikọla nri oriri.
A na-ewere mbadamba mkpụrụ osisi Hartila-D n'ụtụtụ, na-ata ata.
Maximumbọchị a na-agbaso kwa ụbọchị ekwesịghị ịkarị 10 mg.
Usoro onunu ogwu maka oria di iche iche:
- Ọbara mgbali elu - 2.5-5 mg kwa ụbọchị, dabere na nsonaazụ a rụpụtara.
- Ọrịa obi na-adịghị ala ala - 1.25-2.5 mg. Site na iji achọrọ mmụba achọrọ karịa 2,5 mg nwere ike ekewa abụọ.
- Mgbe myocardial infarction, a na-agakọ njikọta nke ramipril + hydrochlorothiazide tupu ụbọchị nke atọ mgbe ọrịa ahụ gasịrị. Usoro onunu ogwu - 2,5 mg ugboro abụọ n’ụbọchị. Enwere ike ịba ụba gaa 5 mg 2 ugboro n'ụbọchị.
- Maka mgbochi nke nkụchi obi, usoro ọgwụgwọ mbụ bụ 2.5 mg, nke na-esote ya ugboro abụọ ka izu abụọ nke nchịkwa, na ọbụna ugboro 2 mgbe izu 3 gachara. Oke mmezi nke ubochi ubochi kariri 10 mg.
Na-arịa ọrịa shuga
Na mmalite ọgwụgwọ, a na-ewere ọkara mbadamba 2.5 nke mg mg 1 otu oge kwa ụbọchị. N'ọdịnihu, ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume ịbawanye ubochi kwa ụbọchị nwayọ gaa 5 mg na usoro abụọ kewara.
Nsonaazụ Hartila D
Ọtụtụ mgbe, ngosipụta ndị na-adịghị mma nke omume nke ọgwụ ahụ metụtara ọrụ nke nri ngwu, hematopoiesis, usoro ụjọ nke akwara, usoro urinary na usoro mkpụrụ ndụ, usoro iku ume, anụ ahụ, usoro endocrine, imeju na akwara.
Ọkpụkpụ afọ
Ogbugbu, vomiting, ọnụ akọrọ, stomatitis, nsogbu ọnya.
Ahụhụ Hematopoietic
Site na akụkụ ahụ na hemopoietic, mgbanwe na nyocha nke ndị na-egosi ga-ekwe omume:
- ọkwa hemoglobin (idebe, ihe anaemia);
- ọnụ ọgụgụ mkpụrụ ndụ ọbara ọbara, sel ọbara ọcha na platelet (ibelata);
- ọkwa calcium (dobe).
Sistemụ akwara Central
Mmalite nke enweghị mmasị, oke ụra, nchegbu, itinye ntị na ntị, isi ike na adịghị ike agaghị ebelata.
Site na usoro urinary
Nkparita nke akụrụ nwere ike ịkpalite oliguria,
Site na sistem iku ume
Ọrịa puru iche, rhinitis, akọrọ ụkwara, ume iku ume.
Na anụahụ
Rash, paresthesia, ịba ụba mmụba, mmetụta nke okpomọkụ n'akụkụ ụfọdụ nke anụ ahụ, alopecia.
Ojiji nke Hartila-D nwere ike ibute oke igba aja.
Site na usoro mkpụrụ ndụ ihe nketa
Mbelata libido, ọgbụgba arụ.
Site na usoro akwara obi
Ibute ọbara mgbali elu mgbe ebili ma ọ bụ guzoro ọtọ, obi ọgbụgba, obi mgbawa nke ọrịa Raynaud.
N'ihe banyere ọdịda dị oke ma sie ezigbo ike n'ọbara, enwere ike ịmalite ịrịa ọrịa myocardial infarction ma ọ bụ ọrịa strok.
Usoro endocrine
Mmụba glucose ọbara na uric acid.
N'akuku nke imeju na akụkụ biliary
Jaundice cholestatic, ịba ọcha n'anya, ọrịa imeju, cholecystitis, necrosis imeju.
Ahụhụ
Mmeghachi omume nfụkasị nwere ike ime n'ụdị:
- urticaria;
- ụba fotoensitization;
- anioedema nke ihu ma ọ bụ ogwooro;
- nkwonkwo nkwonkwo ụkwụ;
- nkọcha;
- conjunctivitis, wdg.
Ojiji Hartila-D nwere ike ibute mmeghachi omume nfụkasị ụdị ọrịa urtikaria.
Site na mmeghachi omume nfụkasị ahụ dị ukwuu, a na-akagbu mbadamba nkume ndị ahụ.
Mmetụta ikike ịchịkwa usoro
Ebe ọ bụ na iji usoro ndị dị mgbagwoju anya na-achọ nlebara anya, mgbe ahụ, enyere onye ọ bụla ohere ị toụ ọgwụ ahụ, mmadụ kwesịrị ịhapụ ịnya ụgbọ ala na ụgbọala ndị na-arụ ọrụ ma ọ dịkarịa ala na mmalite ọgwụgwọ.
Nsonaazụ ndị ọzọ na - apụta n'ụdị:
- hyperkalemia
- hyperazotemia;
- hypercreatininemia;
- ụba Nri nitrogen;
- mgbanwe na ihe ngosi ndi ozo.
Usoro akwara ahụ na - emeghachi ọgwụ ahụ site na nkwarụ akwara, ọrịa ogbu na nkwonkwo na, ọ na-esiri ike, ahụ mkpọnwụ
Ntụziaka pụrụ iche
Jiri n'oge ime na lactation
Ọgwụ na-ike contraindicated na nke abụọ na nke atọ trimesters nke ịtụrụ ime. N'oge a, oke mmetụ ahụ axụrụma dị na nwa ẹmbrayo. N'ihi mmetụta nke ihe ndị dị n’ọrụ nke ọgwụ ahụ, nwa ebu n’afọ nwere ike:
- arụ ọrụ ezumike;
- igba azu;
- oligohydramnios;
- egbula oge iwepu okpokoro isi.
Hartil-D machibidoro iwu nke ọma n'afọ nke abụọ na nke atọ nke ịtụrụ ime.
N’ọdịnihu, ọrịa nke ụmụ amụrụ ọhụrụ nwere ike ịmalite:
- ọbara mgbali ala;
- hyperkalemia
- thrombocytopenia.
Ebe ọ bụ na enwere mmiri ara ehi enwere ọgwụ mgbochi, ọ dị mkpa ịhapụ ị breastụ ara.
Nhọpụta nke Hartil D nye ụmụaka
Emebeghị nnyocha banyere mmetụta ọgwụ ahụ nwere n'ahụ ụmụaka, yabụ, tupu afọ iri na asatọ, edeghị ya.
Jiri na agadi
Jiri nwayọ nwayọ na doses dị ntakịrị.
Ngwa maka ọrụ ezughi oke ọrụ
Na ọdịda akụrụngwa, a ga-agbazi usoro na usoro ọgwụgwọ ya.
Maximumbọchị kachasị kwa ụbọchị ekwesịghị ịfe 5 mg.
Na ọdịda akụrụngwa, a ga-emezi usoro ọgwụgwọ Hartila-D na usoro ọgwụgwọ ya.
Jiri maka ọrụ imeju na-arụ ọrụ
Oke kachasị kwa ụbọchị n'ihe banyere ọrụ imeju na-arịa ya ekwesịghị ịdị elu karịa 2.5 mg, yana ọgwụgwọ, n'ihi mmachi ezighi ezi nke ọgwụ ahụ, a na-eme naanị n'okpuru nlekọta dọkịta.
Do Overụbiga Hartil D
Ọ na-egosi:
- ogwe
- mbelata nke ukwu nke ọbara mgbali;
- njigide urinary;
- mgbochi ụbụrụ;
- obi obibia nsogbu, wdg.
Otu ihe dị mkpa ga - eme bụ iji carbon na sodium sulfate rụọ ọrụ.
Usoro ọgwụgwọ ọzọ na-adabere na mgbaàmà ahụ, yana oge nke ọgwụ na usoro onunu ogwu.
Mmekọrịta na ọgwụ ndị ọzọ
Enwere ike iji ya na thrombolytics, beta-blockers, acetylsalicylic acid.
A choro nlebara anya nke oma n'ihe banyere nkwonkwo ochichi nke akọwara ogwu a:
- diureta;
- ọgwụ nkpuchi;
- ọgwụ mgbochi tricyclic;
- nitrates;
- vasodilators;
- ọgwụ mgbochi.
Ikekwe ojiji nke Hartila-D nwere acetylsalicylic acid.
Yabụ, nchịkwa nke oge ya na ihe mmetọ na-eme ka mbelata ọbara mgbali elu.
Mgbe ejiri thiazide diuretics mee ihe, mmụba nke ọkwa calcium ọbara ga-ekwe omume.
Anfọdụ ọgwụ mgbochi, nitrates na-ahụkarị (ọgwụ nitroglycerin), ọgwụ antipsychotic, na ọgwụ mgbochi tricyclic na-enye otu mmetụta.
Ọgwụ na-abawanye ọkwa nke potassium na ọbara (dịka ọmụmaatụ, ọgwụ na-egbu potassium dị ka Spironolactone, Triamteren, Renial, wdg), cyclosporins nwere ike inye mmetụta nke hyperkalemia.
Ngwunye lithium na-egbu egbu karị mgbe ejiri ya na ndị na - egbochi ACE, yabụ agwakọtala na otu ọgwụ.
Hypokalemia nwere ike ịmalite mgbe ejiri ya glycosides cardiac na ụfọdụ ọgwụ antipsychotic.
Mmetụta antihypertensive na-akụda njikọta ahụ na ọmịiko na ogologo oge iji ọgwụ mgbochi na-abụghị steroidal.
Mmanya ndakọrịta
Ọ ga - ekwe omume ịbawanye nsonaazụ mmanya, yabụ anaghị atụ aro ịbanye na nkwonkwo.
Analogs
E nwere analogues nwere otu ihe aru di otu aru na otu usoro onunu ogwu:
- Amprilan nl (Slovenia) - mbadamba 30;
- Ramazid n (Malta ma ọ bụ Iceland) - 10, 14, 28, 30 na 100 iberibe.
A na - enweta ọgwụ ndị yiri ya.
- Tritace gbakwunyere;
- Enalapril;
- Enap R;
- Prestarium na ndị ọzọ
Ahịa ọgwụ na-ahapụ okwu
E wepụtara ya na ndenye ọgwụ.
Enwere m ike ịzụta na ndenye ọgwụ
Onweghị ọgwụ ọ bụla anaghị enye.
Ego diri Hartil D
Ofgwọ nke mbukota mbadamba na mkpụrụ ego 28 bụ:
- site na 455 rubles - 2.5 mg / 12.5 mg;
- site na 590 rubles - 5 mg / 25 mg.
Ọnọdụ nchekwa maka ọgwụ
Ọ na-atụ aro ịchekwa ọgwụ ahụ na okpomọkụ na-agaghị akarị + 25º C n'ebe a na-agaghị enweta ụmụaka na anụmanụ.
Ọ na-atụ aro ịchekwa Hartil-D na-enweghị ọnọdụ na-adịghị elu + 25º C.
Bọchị mmebi
Akara akara ụbọchị emechi na nkwakọ. Ejikwala afọ atọ gachara site na ụbọchị rụpụtara.
Emeputa
Mmepụta German nke ụlọ ọrụ "Alfamed Farbil Artsnaymittel GmbH" n'obodo Gottingen.
A na-emepụta ya na ụlọ ọrụ mlọ Ọrụ Na-emepụta Ngwakọta EGIS CJSC na Hungary.
Hartil D nyocha
Ndi Okacha Cardio
Anton P., kadiologist, Tver
Omume egosila ịdị irè nke ọgwụ n'ọgwụgwọ ọbara mgbali elu. Ọ dabara na iji ya mgbe a na-egosipụta njịkọ nke ACE inhibitors na diuretics.
Elena A., kadiologist, Murmansk
Ọgwụ dị irè, nke nwekwara ike iji gbochie nkụchi obi. Naanị ihe na-adịghị mma bụ ọtụtụ mmetụta ndị ọ na-akpata, mgbe ụfọdụ na-adị njọ.
Ndị ọrịa
Vasily, dị afọ 56, Vologda
Anọwo m na-arịa ọbara mgbali ọtụtụ afọ. Ihe dị ka ọnwa abụọ gara aga, enwetara m ọgwụ a na dọkịta. N'oge mbido, ọgbụgba na-emekpa ahụ ma na-egbu mmụọ ntakịrị. Ọ gwara dọkịta ahụ ma mgbe usoro ọgwụgwọ ahụ gbanwere ntakịrị, ihe niile malitere ịdị, ma ugbu a, ahụike m adịghị mma.
Ekaterina, gbara afọ 45, obodo Kostroma
Mgbe dọkịta depụtara ọgwụ ndị a, ọ kọwara na ebe ọ bụ na a chọrọ ọgwụ ngwakọta maka ọgwụgwọ, nke a yiri ka ọ bụ nke kachasị mma na nke a. Ọ dị mma ị were ya otu ugboro n'ụbọchị, ọ dịghịkwa mkpa icheta ma ị ga-eri ya tupu nri, n'oge ma ọ bụ mgbe ọ gachara. Ọ bụrụ na echefuru tupu nri ụtụtụ, mgbe ahụ ị nwere ike ị drinkụ mmanya ma emesịa. Naanị nsogbu - na ụbọchị ole na ole mbụ ka m hapụ ịkwọ ụgbọ ala, ebe isi m na -wusi ike. Mana ihe niile mechara pụọ, ugbu a ana m a medicineụ ọgwụ a kwa ụbọchị.
