A na-eji Siofor 500 eme ka glucose ọbara dị ala. A na-ejikwa ya n'ọnọdụ ebe ọ dị mkpa iji dozie ma belata. Nnukwu ọgwụ a na-arụpụta bụ n'ihi nsonaazụ dị mgbagwoju anya: ọtụtụ usoro biochemical na-ahazi n'oge ọgwụgwọ.
International Nonproprietary Aha
Metformin
A na-eji Siofor 500 eme ka glucose ọbara dị ala.
ATX
A10BA02
Ha weputara udi ya na ihe mebere ya
N'ime ụlọ ahịa ọgwụ, ị nwere ike ịchọta ọgwụ naanị n'ụdị mbadamba. Na nkọwapụta ọgwụ a na-enyocha, a na-ezochi usoro onodu ogwu (metformin hydrochloride) - 500 mg. E nwere ụdị ọgwụ ọzọ dị iche na oke nke ihe a: 850 na 1000 mg.
A na-emepụta ọgwụ ahụ na ngwugwu sel nke nwere 10 na 15 mbadamba. Onu ogugu nke blisters na igbe kaadi: 2, 3, 4, 6, 8, 12.
Omume ọgwụ
Siofor bụ otu nke ndị ọrụ hypoglycemic. Ọgwụ a bụ nke biguanides. A na-ejikarị ya ọzọ na njikọta n'ụzọ ndị ọzọ. Ọzọkwa, a na-enye ọgwụ ahụ naanị maka ọrịa shuga na-abụghị insulin. Kpọtụrụ ọgwụ ahụ anaghị emetụta mmalite nke homonụ, a hụrụ mmetụta na-apụtaghị ìhè. Yabụ, n'oge ọgwụgwọ ya na Siofor, ịba ụba nke imepụta insulin site na mkpụrụ ndụ akwara. Agbanyeghị, enwere mmụba na ahụ anụ ahụ na homonụ a.
Usoro nke metformin sitere na mweghachi nke ọtụtụ usoro mmiri ọgwụ:
- ọnụego ojiji nke glucose na-abawanye, n'ihi nke a, glycemia ji nwayọọ nwayọọ belata;
- nha nke usoro nke oriri nke carbohydrates site na akwara nke digestive tract na-ebelata;
- imepụta glucose na imeju na-eji nwayọ nwayọ;
- ike nke inulin nke insulin na-ebelata.
N'ihi mmetụta dị mgbagwoju anya na usoro nke na-eso na njikọta na ojiji nke glucose, a na-achọpụta mbelata nke itinye uche ya na plasma ọbara. Na mgbakwunye na nke a, mpaghara Siofor nọ n'ọrụ na-emetụta mmepụta nke glycogen. N'otu oge ahụ, ike ụgbọ njem nke protein glucose membrane na-abawanye.
Siofor bụ otu nke ndị ọrụ hypoglycemic.
N’agbanyeghi enweghi mmetụta na-esi n’ime insulin arụpụta ihe, a na-achọpụta mbelata nke ogo insulin na-enwere n'efu. Na nke a, enwere mmụba na nha nke insulin na proinsulin. N'ihi usoro ndị a, ọgụgụ anụ ahụ na homonụ a na-abawanye.
Ma, ọgwụ nwere mmetụta na metabolism lipid. N'ime usoro a, mmepụta nke abụba n'efu anaghị amalite nke ọma. Abụba na-adalata ngwa ngwa. N'ihi nke a, ike usoro nke abụba metabolism na-ebelata, nke na-enyere aka ịkwụsi ike. Nbelata nke cholesterol (ma mkpokọta ma LDL), yana triglycerides, belatara. N'ihi ya, a na - agbaghasị usoro nke ịmịcha abụba. Site na nke a, a na-ebelata ibu megide usoro nri ma nọgide na-enwe mmega ahụ zuru oke.
Akụkụ ọzọ nke metformin bụ ikike iji metụta usoro thrombosis. Ngwongwo a egosiputaghi nke oma. Ekele ya, Siofor na-akwalite resorption nke clots.
Mlọ ọgwụ
Akụkụ ahụ na-arụ ọrụ na-abanye n'ọbara ọbara site na mgbaze nri, ebe mucosa na-abanye ngwa ngwa. Mbadamba ndị ahụ bụ ihe eji ekpuchi fim. Ihe a na - enye aka na mwepụta nke ihe na - arụ ọrụ bụ naanị eriri afọ. Mkpuchi plasma kachasị elu nke metformin ruru mgbe awa 2.5 gachara. Nri so mee ka a slowụọ ọgwụ ngwa ngwa.
Metformin na-agbasa ahụ niile. Agbanyeghị, ruo n'ọtụtụ, akụkụ a na-egbu oge naanị na ụfọdụ akụkụ ahụ (imeju, akụrụ) yana yana gland ndị dị na ume. Usoro ndu ogwu ahu n’ahu aru nwere aru ruru 60%. Siofor dị iche na analogues na enweghị ikike nke ijikọ na protein plasma.
Siofor 500 na-arụ ọrụ adịghị enweta mgbanwe.
Ihe nọ n'ọrụ anaghị enweta mgbanwe. Mgbe ewepụrụ ya n’ahụ, akụrụ na-etinye aka. Nkeji ọkara bụ 6.5 awa. Achọpụtala na ọ bụrụ na arụ ọrụ ezinaụlọ yana ọrụ ya, yana mbelata mgbakwunye nke creatinine, ọnụego mwepụ nke metformin n'ahụ ahụ na-ebelata. N'ihi ya, ọnụ ọgụgụ nke ihe na-arụ ọrụ na plasma na-abawanye ozugbo.
Gịnị ka enyere ya?
Isi ụzọ eji Siofor nwere mkpokọta metformin 500 mg bụ ọgwụgwọ nke ndị ọrịa nwere ụdị shuga 2. Ihe ngosipụta maka iji ọgwụ a bụ mmụba nke glucose ọbara. Agbanyeghị, ọgwụ ahụ ka a ga - edenye maka ọgwụ shuga na-abụghị insulin. Nke a bụ n'ihi eziokwu ahụ bụ na Siofor na-eme ka nkwupụta anụ ahụ dị na insulin. Yabụ, mmụba nke ihe mmadụ na-eme n’ọba nwere ike ibute ọrịa.
Ọgwụ a na-atụle akwadoro maka iji oke ibu, nke mepụtara megide mmalite nke ọrịa shuga. Agbanyeghị, ọ bụ ihe amamihe dị na ya iji Siofor yana usoro ọgwụgwọ nri na mmega ahụ na-adịghị mma. Ejiri ọgwụ a na ọgwụ ndị ọzọ. Ọtụtụ mgbe, (na 5-10% nke ikpe), a na-atụ aro ka iji ya dịka usoro ọgwụgwọ nke onwe.
Ihe ngosipụta maka iji ọgwụ a bụ mmụba nke glucose ọbara.
Ihe ngbanwe
Ọ bụ adịghị mma ịkọwa ọgwụ ahụ n'ọnọdụ ndị dị otú a:
- ụdị 1 ọrịa shuga mellitus;
- mmeghachi omume nke ọdịdị na-adịghị mma maka ihe na-arụ ọrụ ma ọ bụ inyeaka na mejupụtara Siofor;
- mmebi nke metabolism metabolism na ndabere nke ọrịa shuga;
- Ọnọdụ ọrịa pathologies tupu ọrịa;
- ọrịa na ọtụtụ ihe na-adịghị mma na-akpata ọrụ imeju na-arịa ya, ndị a gụnyere ọrịa siri ike, akpịrị ịkpọ nkụ;
- ọrịa na - eduga na mmepe nke hypoxia: arụ ọrụ nke obi, usoro iku ume, infarction myocardial, ọnọdụ ụjọ;
- mmụba dị oke mkpa na lactate, yana mmebi nke pH nke ọbara na ngosipụta nke elektrik nkịtị;
- nsị ethanol, mmanya na-egbu egbu;
- usoro ọgwụgwọ nri, ma ọ bụrụhaala na kalori kwa ụbọchị hà ma ọ bụ erughị 1000.
Jiri nlezianya
Achọrọ nlekọta pụrụ iche mgbe ị na-agwọ ụmụaka site na 10 ruo 12 afọ. Na mgbakwunye, a ga-akpachara anya mgbe ị na-a theụ ọgwụ ahụ na agadi (site na afọ 60 ma ọ bụ karịa), ma ọ bụrụhaala na onye ọrịa ahụ nwere mgbatị ahụ siri ike. N'okwu a, enwere ike ịmalite lactic acidosis, tinyere elektrolyte enweghị atụ, mmụba nke ọdịnaya lactate na mmebi nke pH nke ọbara.
Etu esi ewere Siofor 500?
Edere ọgwụ a n'oge nri ma ọ bụ mgbe nri ahụ gasịrị. A na-ekpebi oge ọ ga-eji gwọọ ọgwụgwọ n’otu n’otu. Bido usoro ọgwụgwọ na obere opekampe. Nke nta nke nta, ọnụọgụ nke metformin na-abawanye. Ọzọkwa, usoro ya ga-abawanye kwa izu. N'ihi nke a, anụ ahụ na-eme ka ihe ka-aghọrọ nke ọma.
Edere ọgwụ a n'oge nri ma ọ bụ mgbe nri ahụ gasịrị.
Ọrịa mamịrị
Na mbido mbụ, a ga-ewere 500-1000 mg ọgwụ ahụ. Nke nta nke nta, a na-enweta ọgwụ kachasị elu kwa ụbọchị - 3000 mg (maka ndị ọrịa okenye). Ekepụtara ọgwụ ahụ akọwapụtara na usoro atọ.
A na-eme ọgwụgwọ nke ụmụaka dịka ntuziaka ndị ọzọ si dị, mana enwere obere ọdịiche: n'ime izu abụọ mbụ, 500 mg kwa ụbọchị kwesịrị ị takenụ. Mgbe ahụ usoro Siofor kachasị elu kwa ụbọchị ga - eji nwayọọ nwayọọ rute - 2000 mg (maka ndị ọrịa site na afọ 10 ruo afọ 18).
Maka ịdị felata
Nyere na enwere ike inye ndi mmadu oria mellitus ogwu a ka o gha enyere ogwu ahu, iji belata oke ahu, o nwere ike iji usoro ọgwụgwọ gwaa ya. Ọzọkwa, a ga-enyerịrị iri nri na mmega ahụ ọfụma. Ọgwụ nke nọ n’agha enweghị ike dochie usoro ndị a.
Nsonaazụ
Lactic acidosis na-etolite, a na-akpaghasị uche nke vitamin B12.
Ọkpụkpụ afọ
Achọfu uto, ọgbụgbọ na-egosi, obere oge - ọgbụgbọ. Ọrịa shuga nwere ike ime. Mgbe ụfọdụ enwere mgbu n’afọ. Agụụ na-esogbu onwe ya, n'otu oge ahụ enwere ọla nke dị n'ọnụ n'ọnụ. Mgbaàmà ndị a nwere ike ịpụ n'anya nke onwe ha ma ọ bụrụ na a na-aga n'ihu na ọgwụgwọ, na-a theụ ọgwụ ahụ ugboro abụọ n'ụbọchị. Ihe ọghọm nke mmetụta azụ na-abawanye na mbido ọgwụgwọ mbụ. N'okwu a, anụ ahụ emetụbeghị metformin.
Ahụhụ Hematopoietic
Ọbara
Na anụahụ
Itching, hyperemia, ihe otutu.
Ahụhụ
Urticaria.
Ntụziaka pụrụ iche
Metformin na-agbakọta n'ime ahụ n'oge ọgwụgwọ na Siofor. Site na arụ ọrụ imeju ma ọ bụ akụrụ, mmetụta a na-agbasi ike. N'ihi mmụba nke mkpokọta metformin, ọnụ ọgụgụ lactic acid dị n'ọbara na-abawanye. N'ihi ya, lactic acidosis malitere. N'okwu a, achọrọ ịkwụsị ozugbo ọgwụgwọ ya. Itlọ ọgwụ onye ọrịa dị mkpa.
Nchikota nke metformin na mmanya nwere mmanya na - akpata ihe ojoo.
Iji gbochie mmepe nke lactic acidosis, a na-ekpebi ihe niile nwere ihe ize ndụ na, ọ bụrụ na ọ ga-ekwe omume, ewepụrụ ha n'oge ọgwụgwọ. Ihe na-akpata mgbaàmà nke ọrịa a:
- mmanya na-egbu egbu
- afọ imeju;
- ibu ọnụ;
- hypoxia.
Tupu iwere Siofor, ọ dị mkpa iji chọpụta ọkwa nke creatinine. Nke a bụ n'ihi eziokwu ahụ bụ na akụrụ ji arụ ọrụ na-arụ ọrụ.
Ọ dị mkpa iji nkwụsịtụ iji were ọgwụ ahụ mee ihe ajụjụ tupu ịmalite ọmụmụ ihe site na iji ndị na-eme ka ọdịiche nke ayodiin nwere. Ruptedbọchị ọgwụgwọ ya ka ọ kwụsịrị ụbọchị abụọ tupu ụbọchị a họpụtara wee gaa n'ihu ụbọchị 2 mgbe nyocha.
Mmanya ndakọrịta
Nchikota nke metformin na mmanya nwere mmanya na - akpata ihe ojoo.
Mmetụta ikike ịchịkwa usoro
Siofor adịghị enye aka na mbelata nke ukwuu na glycemia, yabụ, enweghị mgbochi mgbe ị na-anya ụgbọ ala n'oge eji ngwa a. Agbanyeghị, ekwesịrị ịkpachara anya mgbe ị na-anya ụgbọala.
Jiri n'oge ime na lactation
Ejila ya na ọgwụgwọ nke ndị ọrịa n'ọnọdụ ndị a, n'ihi na enweghị ozi zuru oke banyere nchekwa nke ọgwụ.
A naghị atụ aro ka ịnwere ngwá ọrụ a maka ndị ọrịa na-erubeghị afọ 10.
Nhọpụta Siofor nyere ụmụaka 500
A naghị atụ aro ka ịnwere ngwá ọrụ a maka ndị ọrịa na-erubeghị afọ 10.
Jiri na agadi
A kwadoro ọgwụ a maka iji ya.
Ngwa maka ọrụ ezughi oke ọrụ
Ọ nwere oke mmerụ ahụ na-akpata mmachibido iji Siofor iji weghachi ọkwa nke glycemia na ọrịa shuga mellitus. Mkpebi a na-ekpebi bụ mbelata creatinine na 60 ml kwa nkeji.
Jiri maka ọrụ imeju na-arụ ọrụ
N’ime ọrịa siri ike nke akụkụ a, a naghị akwado Siofor.
Dodoụbiga ya ókè
Ọ bụrụ na a aụrụ ọgwụ metformin 85 g, mmetụta ndị ahụ anaghị etolite. Mgbe ọnụọgụ nke ihe bara ụba karị, ohere nke lactic acidosis na-abawanye. N'okwu a, achọrọ ụlọ ọgwụ. Belata mkpokọta lactic acid na metformin n'ọbara site na iji hemodialysis.
Mmekọrịta na ọgwụ ndị ọzọ
Ngwakọta ndị amachibidoro
Ndakọrịta nke ndị nwere ọdịiche nwere iodine na Siofor anabataghị. N'okwu a, ihe ọghọm nke ịmalite itolite akụrụ na-abawanye, nke ihe ịrịba ama nke lactic acidosis pụtara.
Ndakọrịta nke ndị nwere ọdịiche nwere iodine na Siofor anabataghị.
Ngwakọta anaghị atụ aro
A drinkụla mmanya mgbe ị na-a theụ ọgwụ ịchọrọ. N'otu oge ahụ, ihe ize ndụ nke ịmalite lactic acidosis na-abawanye. Nsonaazụ yiri nke ahụ na-enye ngwakọta nke ọgwụ metformin na ethanol nwere.
Mgwakọta chọrọ ịkpachara anya
Danazole na-enyere aka ịbawanye glycemia. Ọ bụrụ na ọ dị mkpa ịchọrọ ị medicationụ ọgwụ a, achọrọ ịgbanwetụ nke metformin.
Ọkwa glucose na-abawanye na njikọta nke ndị na - eso ya, ihe:
- mẹ ụnwunna iya;
- homonụ thyroid;
- Epinephrine;
- nicotinic acid;
- glucagon;
- usoro nke phenothiazine.
Rationbara Siofor na-abawanye nke ukwuu na ọgwụgwọ Nifedipine. Morphine na ọgwụ cationic ndị ọzọ na-enye otu mmetụta.
Ngwakọta nke sulfonylureas, insulin - ọgwụ ndị a na-akpalite mmụba na ihe metformin.
Ọgwụ a na-enyocha na-enyere aka belata ịdị irè nke anticoagulants na-apụtaghị ìhè (aspirin, wdg).
Analogs
Mwere dochie Siofor:
- Diaformin;
- Glyformin;
- Glucophage Long;
- Mpempe;
- Metformin na ndị ọzọ
Ọnọdụ ezumike Siofora 500 sitere na ụlọ ọgwụ
Ogwu bu ogwu.
Enwere m ike ịzụta na ndenye ọgwụ?
Ee e, ịnwere ike ịzụta ọgwụ ahụ naanị ka dọkịta gị gwara gị.
Ọnụahịa
Nkezi ọnụ bụ 250 rubles.
Ọnọdụ nchekwa nke Siofor 500
Okpomoku kacha ikuku gbara anya bụ + 25 Celsius.
Bọchị mmebi
Ọgwụ ahụ na-ejigide Njirimara maka afọ 3 site na ụbọchị ewepụtara.
Emeputa
Berlin - Chemie AG (Germany).
Nyocha banyere Siofor 500
Ndi dibia
Vorontsova M.A., 45 afọ, endocrinologist, Kaluga
Edere m ọgwụ ahụ na ọgwụ insulin na-eguzogide. N’etiti ndị ọrịa m, e nwekwara ụmụaka nọ n'afọ iri na ụma. A nabatara ọgwụ a nke ọma, ihe ngosi ndị na - adịghị mma na - apụta nwa oge na - esite na eriri afọ. Na mgbakwunye, ọnụahịa ahụ dị ala, ma e jiri ya tụnyere analogues.
Lisker A.V., onye gbara afọ 40, onye na-agwọ ọrịa, Moscow
Ọgwụ na-eme ihe ngwa ngwa, dị oke irè. Maka nke a, enwere ike iji ya mee ihe maka ịgwọ ọrịa hyperglycemia na ebumnuche nke ifelata naanị mgbe ịgachara dọkịta. Siofor apụtaghị n'ọtụtụ analogues na nke ọ nwere ike itinye aka n'ịkpa ọnọdụ ahụ yana akwa polycystic. N'okwu a, ụmụ nwanyị nwere akara dị iche iche: ntutu dị n'ahụ na ihu, ibu na-abawanye. Ọgwụ nwere mmetụta na-agbanwe agbanwe na oke nke homonụ, a na-ahụ na iwepụ ntutu n’ahụ, belata ibu.
Ndị ọrịa
Veronika, afọ 33, Samara
O were hyperglycemia were ogwu ahu. Siofor mere ihe ngwa ngwa. Ahụghịkwa m mmetụta na-adịghị mma na onwe m.
Anna, 45, Sochi
Ọgwụ enweghị ego ma dịkwa irè. Achọpụtara ọrịa shuga mellitus ogologo oge, n'ọnọdụ m, ọ siri ike ịhọrọ ọgwụ hypoglycemic, ahụ adịghị ahụ ha. Ma Siofor dị nwute na ọ dị nro.
Ibelata ibu
Olga, 35 afọ, obodo Kerch
Ebu belata m mgbe m na-a remedụ ya. Enwere m olile anya na kilogram abụọ ga-apụ. Ibu ibu ka guzoro, mana opekata mpeghi ya, nke dịkwa mma.
Marina, 39 dị afọ 39, Kirov
Ọ na-eme egwuregwu siri ike (o kwere mee ya na ọrịa shuga), enwere nri edozi. Nsonaazụ esighi ike - ịdị arọ ya anaghị ada. Ma m na-agbaso usoro ọgwụgwọ ahụ maka nwa oge, ma eleghị anya nke a bụ isi okwu.
