Ọtụtụ mmadụ na-arịa ọrịa shuga. Ọzọkwa, kwa afọ ọnụ ọgụgụ ndị na-arịa ọrịa a na-arịwanye elu.
Ọ gaghị ekwe omume ịgwọ ụdị ọrịa a, agbanyeghị, ọ ga - ekwe omume ịchịkwa ya ma jigide ọnọdụ ahụ nkịtị.
Iji mezuo nke a, mepụta ọgwụ dị iche iche, otu n'ime ya bụ Amaryl. Nyocha na-a theụ ọgwụ ahụ na-abụkarị nke dị mma. Isi ihe bụ ịchekwa usoro onunu ogwu na oge nchịkwa. Gụkwuo banyere ọgwụ na edemede a.
Omume ọgwụ
Me nkwadebe nke otu sulfonylurea na-ezo aka na ndị na - ahụ ihe hypoglycemic maka iji ọnụ. Site na igbochi ọwa mmiri ọgwụ cytoplasmic potassium ATP nke mkpụrụ ndụ beta dị na pancreas, mkpali nke nzuzo na-eme.
N'ihi ya, a na - ahapụ insulin n'ahụ sel beta, nke na - egosi nsonji palọ. A na - ahụkarị nsonaazụ extrapancreatic, n'ihi nke a na - eme ka ọrụ insulin dịkwuo mma.
Amaril
Ngwakọta ọgwụ a na-arụ ọrụ na-enwe ike ijikọ ngwa ngwa yana protein beta-cell. Molekpụrụ ya dị n’olu bụ 65 kD / SURX. Enwere exocytosis nke insulin. Ọ dị mkpa na ihe homonụ na mmetụta ya abaghị uru bụ isi ihe iji belata ihe ize ndụ hypoglycemia.
Amaryl nwekwara antioxidant, antiplatelet, mmetụta anti-atherogenic. Nsonaazụ ya gbasaara na sisitemu obi, na-ebelata insulin iguzogide. Ojiji glucose site na akwara na anụ ahụ adipose na-abawanye n'ihi ọnụnọ protein na-ebugharị nke ọma.
Site na ịba ụba n'ọrụ ha, ngwá ọrụ na-enyere aka ịbawanye glucose dị mma. Lipogenesis na glycogenesis nwekwara njikọ.
A na-egbochi mmepụta glucose hepatic, n'ihi nke ọnụọgụ nke fructose-2,6-bisphosphate na hepatocytes na-abawanye.
A na-egbochi nzuzo nke COX n'oge a na-achịkwa ọgwụ ahụ, arachidonic acid na-ebelata mgbanwe ahụ. Nke a na - enyere aka belata nchịkọta platelet, ee, enwere mmetụta antithrombotic.
Alfa-tocopherol na-abawanye mgbe ekpughere ya ọgwụ. Na mgbakwunye, a na-eme ka ọrụ nke superoxide dismutase, catalase, glutathione peroxidase, a na-ebelata mmeghachi nke oxidative na-eme na ọrịa shuga mellitus.
Ihe ngosi maka ojiji
Emebere Amaryl naanị maka iji ụdị shuga 2 mee ihe. Jiri ya dị ka ọgwụgwọ monotherapy, yana maka ọgwụgwọ njikọta. Ọgwụ Amaril maka ụdị ọrịa shuga 2 nwere nyocha dị mma mgbe ejiri ya na metformin ma ọ bụ insulin.
Ngwakọta nke ọgwụ ahụ, ụdị ntọhapụ
A na-emepụta Amaryl n'ụdị mbadamba, nke nwere ike ịnwe ọgwụgwọ dị iche, ya bụ 1, 2, 3, 4 mg.
Ihe na-arụ ọrụ ebe a bụ glimepiride, na ihe ndị ọzọ na-enyere aka gụnyere lactose monohydrate, magnesium stearate, microcrystalline cellulose, na-acha E132 na E172, povidone.
Mbadamba ụrọ nke ọ bụla nwere ahịrị nkewa, yana kanye. Ihe ngwugwu a nwere blisters abuo n’ime ya bu mbadamba iri na ise.
Ihe ngbanwe
Ekwesighi iwere Amaril na okwu ndia:
- lactation na afọ ime;
- ụdị 1 ọrịa shuga mellitus;
- mmadụ ịghara ịnagide ihe;
- afọ ụmụaka;
- ọrịa mamịrị ketoacidosis;
- ọrịa imeju na akụrụ;
- ụkọ lactose, glucose-galactose malabsorption.
Nsonaazụ
Site n'iji ọgwụ ọjọọ eme ihe n'ụzọ na-adịghị mma, enwere ike ịchọpụta ọtụtụ nsonaazụ:
- emeghasịkwa usoro ụjọ ahụ: iro ụra, enweghị nhazi, nkụda mmụọ, ike ọgwụgwụ, ọgba aghara, ọgbụgbọ, paresis, ịma jijiji, ọgba aghara, nchekasị, nhụsianya nke ntị na ịnụ ntị, oke iwe, nsogbu ịrahụ ụra, isi ọwụwa, enweghị njide onwe onye, nkwarụ;
- sisitemu obi - tachycardia, angina pectoris, ọbara mgbali akwara, bradycardia, nsogbu obi;
- nsogbu metabolic - njirimara nke mmeghachi omume hypoglycemic;
- eriri afọ - mgbu afọ, vomiting, jaundice, afọ ọsịsa, ọdịda imeju, ịba ọcha n'anya, cholestasis;
- sistemụ mgbasa - thrombocytopenia, granulocytopenia, agranulocytosis, erythrocytopenia, hemolytic ma ọ bụ aplastic anaemia;
- mmeghachi omume ndị ọzọ nkwarụ ọhụhụ na iku ume iku ume, hypersensitivity n'ụdị itching, nchachi ọnya, urticaria, vasculitis allergies.
Ntụziaka maka ojiji
Ikwesiri were ụdị ogwu a n'ime n'ime na-adịghị ata ata. Ihe ọ Drinkụ shouldụ kwesịrị ịbụ ọkara ọkara iko mmiri.
Gbalịa ị takeụ ọgwụ a ga-ejikọ ya na nri, ma ọ ga - eyi egwu na nnukwu mbelata nke ọbara.
Nke a pụtara na ị ga-a drinkụ ọgwụ ọ immediatelyụ immediatelyụ ozugbo tupu nri ma ọ bụ n'oge usoro a. A na-eme nke a nke ọma n'ụtụtụ, ọ bụrụ na ngwa bụ otu ụbọchị kwa ụbọchị, ka ị nwee ike ijikwa ọdịnaya shuga.
Usoro mbụ nke ọgwụ ahụ bụ 1 mg nke ọgwụ ahụ kwa ụbọchị. Ọzọkwa, ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume iwelie onunu ogwu ya na nkeji nke 1-2 izu. N'okwu a, ọgwụ ọzọ bụ 2 mg, mgbe ahụ 3 mg, emesia 4 mg, na nke ahụ, 6 mg nwere ike iji ya. Usoro onunu ogwu a bu ihe kacha kwere omume, ekwesighi ka o kari ya.
Ọ ga-abụ dọkịta gharịrị mmụba nke ọgwụ ahụ, dabere na njirimara mmadụ, ụzọ onye ọrịa ahụ, ụzọ ọrịa ahụ.
Enwere ike iwere Amaril na usoro ọgwụgwọ yana insulin ma ọ bụ metformin. N'ọnọdụ ebe Metformin anaghị eweta mbelata shuga dị ala, edepụtara Amaril.
N'ọnọdụ a, a na-ewere Metformin na usoro ị nweburu, Amaryl amalitekwara ị drinkụ obere mmiri nke 1 mg, nke nwere ike jiri nwayọ rute 6 mg. Ọ bụrụ na ngwakọ a abaghị uru, insulin na-edochi Metformin. N'okwu a, usoro ọgwụ nke Amaril adịghị agbanwe agbanwe, a na-ewerekwa insulin na nke kacha mma, na-eji nwayọọ nwayọọ na-abawanye usoro ị theụ ọgwụ.
Dodoụbiga ya ókè
Ọ bụrụ na ọnụego ọgwụ ahụ gafere, mgbe ahụ, a na-atụ onye ọrịa egwu hypoglycemia, na-adịgide awa 12-72.
Mgbaàmà ya bụ otu ihe mmetụta ndị ọgwụ ọjọọ a kpọtụrụ aha na mbụ kwuru. N'ọnọdụ dị oke njọ, enwere ike ịmalite itolite.
Ọ bụrụ n ’ụdị mgbaafọ a, ihe mbụ ịchọrọ iri shuga, drinkụọ mmiri ọ orụ orụ ma ọ bụ tii dị ụtọ. Ọ dị mkpa mgbe niile iburu gị gulut 20 g glu, dịka ọmụmaatụ, ọ nwere ike ịbụ gram 4 nke shuga. Ndị na-atọ ụtọ n'okwu a ga-eweta obere ojiji.
Ọ bụrụ na ikpe ahụ siri ike, mgbe ahụ, a ga-achọ ụlọ ọgwụ. N'ụlọ ọgwụ, a na-eme larịị gastric, a na-achọkwa adsorbents. Ihe nchịkwa glucose dị ezigbo mkpa. A na-ewepụ ihe ịrịba ama ndị ọzọ na-adịghị mma site na ọgwụgwọ Symptomatic.
Mkparịta ụka ọgwụ ọjọọ
Na ọgwụ ndị ọzọ, iji Amaril nwere ike ibute mmụba ma ọ bụ ibelata mmetụta hypoglycemic.
N'okwu nke mbụ, mmetụta ahụ ga-ebelata mgbe ị na-a drugsụ ọgwụ ndị a: homonụ thyroid, adrenaline, chlorpromazine, sympathomimetics, glucocorticosteroids, diazoxide, barbiturates, laxatives, saluretics, thiazide diuretics, glucagon, phenytoin, phenothiazine, acetazolamide acid, nicotin, nicotin , progestogens na estrogens, ntụ ọka lithium.
A na-ahụta mmụba nke hypoglycemic mgbe ị na-eji ọgwụ ọgwụ ndị dị otú ahụ na Amaril: ọgwụ ndị ọzọ maka ọgwụgwọ nke hypoglycemia, angiotensin-na-agbanwe ihe na-egbochi, allopurinol, steroid anabolic, ọgwụ coumarin, tritokvalin, ọgwụ ọjọọ na nwoke mmekọahụ, oxyphenbutazone, pentoxifylline, pentoxifylline, , fibrates, pheniramidol, MAO inhibitors, azapropazone, fenfluramine, probenecid, salicylates, sulfinpyrazone, tetracyclines, tro-, cyclo-, isophosphamide, sulfonyls ogologo oge omume dy.
Nyocha banyere ọgwụ Amaryl
Banyere ọgwụ Amaril, nyocha nke ndị ọrịa mamịrị amamịghe. Ndị ọrịa na-ewere Amaryl kwenyere na ọgwụ a na-alụ ọgụ ike nke ukwuu n'ọrịa shuga nke 2.Isi ihe bụ ịhọrọ ụzọ dị mma ị medicationụ ọgwụ. Akụkụ dị mma bụkwa agba dị iche iche nke mbadamba nkume ahụ, etinyere na usoro dị iche iche. Nke a ga - enyere gị aka ịghara ịgbagha nke dị mma.
Agbanyeghị, enwere ọtụtụ nyocha na-adịghị mma, bụ nke metụtara njikọta na-emekarị, dịka oke ụjọ, ike ọgwụgwụ, ịma jijiji na ahụ, ịbawanye ụba. Enwere ikpe nke hypoglycemia, yabụ ọ dị ezigbo mkpa ibute Grafica ma ọ bụ ngwaahịa ndị ọzọ nwere nnukwu shuga.
Vidiyo ndị metụtara
Nyocha vidiyo nke ọgwụ Amaryl:
N’ihi ya, ọrịa shuga anaghị ebutekarị nsogbu na ahụ erughị ala. Drugsdị Amaril nwere ike ịnwe ọkwa shuga nkịtị.
