Ntụziaka zuru ezu maka ọgwụ Glucofage - otu ị ga-esi maka oke ibu na ụdị shuga 2?

Glucophage bụ ọgwụ hypoglycemic, nke gụnyere metformin, ihe mejupụtara nwere mmetụta antidiabetic.

Ihe dị ike nke ọgwụ ahụ na-ewepụ hyperglycemia na-enweghị mbelata ọnụọgụ ọbara na shuga ọbara. Akpaliteghi mmanu insulin na onodu hypoglycemic na ndi mmadu ike.

Ọ na - eme ka nnabata nke onye na - anabata homonụ peptide na - eme ka nhazi nke carbohydrates dị mfe. Na-ebelata mmepụta glucose site na ibelata metabolism na mmebi nke glycogen. Ọ na - egbochi ike ịnweta carbohydrates dị mfe site na usoro nri.

Metformin na-arụ ọrụ glycogenesis, na-eme ka ikike ịmịnye protein na-ebuwanye ibu, ogo nke metabolism lipid. N'ihi ị Gụ Glucofage, ịdị arọ onye ọrịa ahụ na-eji nke nta nke nta belata. Mmụta emere nwapụta na ọgwụ mgbochi ọgwụ mgbochi ọrịa nke Glucofage n'ime ndị mmadụ nwere mmụba na-abawanye glucose ọbara yana ihe ndị metụtara ihe egwu.

Ihe ogwu a ka egosiwara maka ndi oria ndia, bu ndi gbanwere uzo ndu ha si ebibebeghi oria. Otu esi ewere Glucofage iji zere ịdoụbiga mmanya ókè na nsonaazụ ndị ọzọ dị na ozi enyere n'okpuru.

Ngwakọta na usoro onunu ogwu

Akụkụ nọ n'ọrụ ọgwụ ahụ nwere metformin hydrochloride, polyvinylpyrrolidone pere mpe dị ala, magnesium stearate.

Mbadamba ụrọ dị iche iche

Round, biconvex mbadamba ọcha nke 500 na 850 mg bụ ihe mkpuchi nwere hypromellose. Ndi ikpa nwere otu ihe di no na obe.

Oval, 1000 mg white convex convex n’akụkụ abụọ ya nwere ihe nkiri nke opadra, akara nkewa na ihe edere “1000”.

Ihe ngosi maka ojiji

Ngwakọta ọrụ ọgwụ ahụ na-eme ka metabolism nke abụba dịkwuo mma, na-enyere aka iwepụ lipoproteins na cholesterol.

Isi ihe eji egosi ogwu a bu ndi a.

• ọrịa shuga na-enweghị insulin na oke ibu na enweghị nsonaazụ nke iji nri nri ma ọ bụ mmega ahụ;
• n'ime ndị ọrịa okenye na ụmụaka karịrị afọ 10 dị ka ọgwụgwọ nnwere onwe nke ụdị ọrịa shuga 2 ma ọ bụ ya na ọgwụ ndị ọzọ na-ebelata glucose ọbara.
• mgbochi nke ụdị oria nke 2 n'ụtọ oke ala.

Ihe ngbanwe

Dịka ọgwụ niile nke sitere na kemịkal, glucophage nwere ọtụtụ ihe mgbochi.

Amachibidoro ị drugụ ọgwụ a n'ọnọdụ ndị a:

• hypersensitivity na metformin, ihe ndị ọzọ nke ọgwụ ahụ;
• steeti nke hyperglycemia, ketoanemia, precoma, coma;
• arụ orụ ọrịa syndrome;
• mgbanwe na mmiri nnu nnu;
• ọnya na-efe efe nke ukwuu;
• ọdịda dị egwu nke usoro nke usoro nke usoro ndụ;
• mmebi nke mgbanwe gas na ngụgụ;
• decompensated myocardial dysfunction nwere mgbasa ọbara ọgbụgba;
• nnukwu ischemic necrosis;
• arụmọrụ buru ibu na mmerụ ahụ chọrọ ọgwụgwọ insulin;
• nsogbu nke imeju;
• ị chronicụ mmanya na-egbu egbu na-egbu egbu, ethanol nsị;
• ime
• mụbaa lactate ọbara;
• ntụgharị nke scintigraphy ma ọ bụ ihe nlere foto na ntinye nke ọgwụ dị iche nwere ayodiin;
• rube isi na obere kalori.

Ejiri Glucophage jiri nlezianya mee ihe n'ọnọdụ ndị a:

• imega ahụ dị arọ na nká, nke nwere ike ibute nguzobe acidosis;
• arụ ọrụ ezumike;
• oge lactation.

Usoro usoro onunu ogwu na usoro onunu maka oria shuga

Ozugbo abanye n'ime ngba ahụ, metformin na-abanye kpamkpam.

Zuru oke bioavailability ruru 60%. A na-ahụta itinye uche plasma kachasị 2.5 awa mgbe etinyere.

N’otu oge, nri na-egbu oge iweghara ihe ndị dị n’ọrụ. Metformin na-emeju anụ ahụ ngwa ngwa na-enweghị mmekorita protein.

Ngwa hypoglycemic na-enwe metabolism na-adịghị ike. Emere ya ka ọ bụrụ ntopute akụrụ dị iche iche na ijikọ ọrụ ọwa. Iwepu ọkara ndụ bụ awa 6.5. Ihe ọmụmụ akụrụ na-eme ka oge dị n’etiti dịkwuo ogologo, na-akpalite ihe ọghọm nke inwe kemịkal.

A na-eji ọgwụ ahụ eme ihe kwa ụbọchị, na-enweghị nkwụsịtụ.Maka ndị okenye, mkpụrụ ego mbụ nke ihe - 500 ma ọ bụ 850 mg ekewa ekewa n'ime ihe 2 ma ọ bụ 3. Ejiri nri rie ya ma ọ bụ soro ya rie. Kwa izu abụọ, a na-enyocha ọsụsọ ọbara. Dabere na ndị egosipụtara enwetara, a na-eme mgbazi.

Mmụba nke nwayọ na dose na-egbochi mmetụta ọjọọ nke usoro digestive. Nhazi nke ị drugụ ọgwụ kwa ụbọchị bụ 1500-2000 mg. Ohere a nabatara bu 3000 mg. Ejiri ya ụzọ atọ.

Maka ndị ọrịa na-eji metformin na ọnụọgụ 2000-3000 mg kwa ụbọchị, ọ ga-adị mma ka ị gbanwee na mbadamba 1000 mg. E kewara olu ubochi n’iile n’ime ihe ato.

Njikọ ọgwụ na insulin na-enyere aka ịchịkwa glucose ọbara. Ọnụego ọgwụ mbụ kwa ụbọchị bụ 850 mg. A na-ekewa ya n'ime ojiji 2-3. A na-ahọrọ ọ̀gwụ nke homonụ peptide dabere na shuga ọbara.

Edere Glucophage maka ụmụaka gafere afọ 10. Anabatara iji insulin mee ihe ọzọ. Olu mbu ubochi mbu bu 500 ma obu 850 mg. Were nri ma obu nri mgbe obula. Mgbe izu abụọ gasị, a na-eme mgbazi ọgwụgwọ. Ego nke kachasi ubochi - 2000 mg nke ato.

Nsonaazụ

Mgbe ụfọdụ glucophage na-ebute mmeghachi omume na-adịghị mma nke anụ ahụ. Ọnọdụ ndị a na-adịghị mma:

• lactic acidosis;
• oriri zuru ezu nke vitamin B 12;
• enweghị ụdị ụtọ ihe na-atọ ụtọ;
• oke afọ, afọ, ọgbụgbọ, mkpọchi afọ;
• mgbanwe na arụmọrụ ọrụ nke imeju, ịba ọcha n'anya.

Ọmụmụ ihe ọmụmụ nọ n’afọ ụmụaka dị site n’afọ iri ruo n’afọ iri na isii egosila na ọnụnọ nke nsonaazụ ya na ya bụ mmetụta ọjọọ na ndị ọrịa okenye.

Dodoụbiga ya ókè

Excess excessụbiga oke ókè ma ọ bụ ọnọdụ ndị ọzọ metụtara ya na-ebute mmụba na lactate. Ọdịdị nke mgbaàmà nke mmụba nke lactic acid chọrọ ọgwụgwọ ịkwụsị, ụlọ ọgwụ ngwa ngwa maka usoro ịgwọ ọbara na ọgwụgwọ Symptomatic.

Mkparịta ụka mmanya na-egbu egbu

A naghị atụ aro ka iji ọgwụ antidiabet na ethanol mee ihe n'otu oge.

Mmanya na-egbu egbu na-akpata lactic acidosis na ọnọdụ njikọ ndị a:

• Nri ezughi oke
• nri nwere obere kalori;
• nsogbu nke imeju.

Ime na lactation

Enweghi mmetụta ọgwụgwọ antidiedi n'oge oge ị na-amụ nwa ga-abụ ihe kpatara mmekpa ahụ ọrịa nwa ebu n’afọ na ọnwụ n’afọ.

Ihe omuma banyere mmụba nke erughị eru nke ụmụ aka ebe ụmụ nwanyị dị ime na-anabataghị Glucofage.

Ọ bụrụ n’ịchọpụta ihe ịtụrụ ime n’ezie ma ọ bụ n’atụ ime ime, ịkagbu ọgwụ ahụ. Metformin na-abanye n’ime mmiri ara.

Achọpụtaghị mmetụta ọjọọ nke ọgwụ ahụ na ụmụ amụrụ ọhụrụ, mana ọnụọgụ data na-egosi iji ojiji hypoglycemic ngwaahịa n'oge a.

Njikọ Ọgwụ

Njikọ dị ize ndụ bụ ojiji nke metformin yana akụkụ radiopaque nwere iodine. Na-emegide nzụlite gbasara akụrụ gbasara akụrụ, ọmụmụ dị a na-enye aka na mmepe nke lactic acidosis.

A na-akagbu iji ọgwụ ahụ ụbọchị abụọ tupu ọmụmụ ihe ahụ. Reslaghachi mgbe elekere 48 gachara ọrụ akụrụ.

Nchikota nke Glucophage na ogwu nke edeputara n’okpuru gosiputara dika ndi a:

• Danazole na-akpalite mmetụta hyperglycemic nke metformin;
• Chlorpromazine n'ọtụtụ buru ibu na - eme ka ngwakọta nke carbohydrates dị mfe, belata ntọhapụ nke homonụ peptide;
• analogues nke homonụ endogenous na-eme ka ịbawanye ụba nke glucose, na-akpata nkwụsịtụ nke abụba echekwara;
• diuretics na-akpalite lactic acidosis n'ihu ọnụnọ nke akụrụngwa nke arụrụala;
• inje nke beta2-adrenergic agonists na-eme ka ịbawanye ụba nke glucose ọbara;
• ọgwụ antihypertensive, ma e wezụga ndị ACE na-egbochi, belata nchịkọta glucose;
• n’otu oge iji ọgwụ ahụ eme ihe na njikọta sulfonylurea, homonụ peptide, alfa-glucosidase inhibitors, salicylates na-akpalite hypoglycemia;
• Nifedipine na-eme ka usoro kemịkal nke mmiri nke nnabata nke ihe na-arụ ọrụ dị;
• ọgwụ cationic antibacterial na-asọrịta mpi na metformin maka sistemụ sel, mụbaa ihe mejupụtara ọ kachasị.

Usoro ire na ebe nchekwa

Ọgwụ na-enye ọgwụ ọgwụ naanị. Ọnọdụ nchekwa - ruo 25 Celsius. Ekwela ka ụmụaka ghara iru ya.

O kwere omume ifelata oke ọgwụ

Enwere ndụmọdụ iji nweta oke felata na-enweghị oke mmerụ ahụ ike. Ọ bụ dibịa nọ ebe ahụ ka ọ na-ahọrọ ọnụego ọgwụ otu.

Jiri ntakịrị ịtinye uche, gaa na mmụba nwayọ. Jiri ọgwụ hypoglycemic na-emegide ihe oriri na-edozi ahụ.

Vidiyo ndị metụtara

Dietitian banyere arụmọrụ glucophage: