Gliclazide MV: nkọwa ọgwụ, nyocha banyere iji, ọnụahịa

Gliclazide MB bụ nkwadebe ọnụ nke hypoglycemic metụtara usoro sulfonylurea nke ọgbọ nke abụọ. Ọgwụ:

1. na-akpali mmepụta nke insulin homonụ;
2. na - eme ka insulin-zoro ezo na - arụ ọrụ nke glucose;
3. lowers ọbara shuga;
4. na-abawanye ọgụgụ insulin na akwara anụ ahụ;
5. normalizes larịị nke na-ebu ọnụ glycemia;
6. belata imepụta glucose site na imeju;
7. na mgbakwunye na emetụta metabolism metabolism, ọgwụ na-eme ka microcirculation dịkwuo mma.

Glyclazide na-ebelata ohere nke ọbara ọgbụgba n'ime obere arịa, na-emetụta n'otu oge abụọ na-etinye aka na mmepe nke nsogbu nke ọrịa shuga mellitus:

• ihe mgbochi nke adhesion platelet na nchịkọta;
• maka mgbake;
• iji belata ihe mmado platelet (thromboxane B_2, beta-thromboglobulin).

Ntụziaka maka ojiji na ihe ngosi

Edere Gliclazide yana usoro ọgwụgwọ nri maka ọrịa shuga nke 2, ọ bụrụ na nri na mmega ahụ arụpụtaghị ezigbo nsonaazụ.

Ihe ngbanwe

• ụdị shuga 1;
• nwere mmetụta dị elu na Glyclazide ma ọ bụ ihe ndị mejupụtara ọgwụ ahụ (na sulfonamides, na usoro nke sulfonylurea);
• afọ ime na lactation;
• nnukwu ịba ọcha n'anya ma ọ bụ akụrụ ọdịda;
• na-ewere miconazole;
• ọrịa shuga;
• precca ọrịa shuga;
• ọrịa mamịrị ketoacidosis;
• afọ ruo afọ 18;
• ụkọ lactase;
• enweghi afọ ojuju na lactose;
• Ndị dọkịta anaghị ekwu maka ojiji nke ọgwụ n'otu oge yana yana danazol ma ọ bụ phenylbutazone.

Mgbe e kwesịrị iji nlezianya kpachara anya

Enweghị ike iji Gliclazide na-enweghị ndenye ọgwụ, n'ihi na ọgwụ ahụ adabaraghị onye ọ bụla. Nke a bụ ndepụta nke ọnọdụ ị ga-eji jiri nlezianya rụọ ọrụ:

1. nri na-edozi ahụ ma ọ bụ nke na-adịghị edozi ahụ;
2. ịka nká;
3. hypothyroidism;
4. pituitary ma ọ bụ enweghi afọ ojuju;
5. ọrịa siri ike nke usoro akwara obi (atherosclerosis, ọrịa obi obi);
6. hypopituitarism;
7. ogologo oge ọgwụgwọ glucocorticosteroid;
8. imeju ma ọ bụ akụrụ afọ;
9. ụkọ glucose-6-phosphate dehydrogenase;
10. a .ụrụma.

Attentionaa ntị! Edere ọgwụ ahụ naanị maka ndị okenye!

Etu ị ga - eme n’oge afọ ime na inye nwa ara

Enweghị data maka iji ọgwụ n'oge oge ịgba. Ihe omuma banyere ojiji nke uzo ozo nke sulfonylurea n’oge di ime.

N'ime nyocha ụlọ nyocha na anụmanụ, achọpụtaghị mmetụta teratogenic nke ọgwụ ahụ. Iji belata ihe mmerụ ahụ nke ịmụ nwa, ịchọrọ njikwa ọrịa shuga mellitus (ọgwụgwọ kwesịrị ekwesị).

Dị Mkpa! Edere ọgwụ ọgwụ hypoglycemic n'oge afọ ime. Maka ọgwụgwọ nke ọrịa shuga n'oge ime, a na-ahọrọ insulin ọgwụ. Ismata ọgwụ hypoglycemic ka akwadoro iji dochie insulin.

Ọzọkwa, iwu a metụtara ikpe ahụ mgbe ime mere n'oge ị ofụ ọgwụ, ma ọ bụrụ na ịtụrụ ime bụ naanị na atụmatụ nwanyị ahụ.

N'iburu n'uche na enweghi data banyere ị ofụ ọgwụ na mmiri ara ara, ewepụghị ihe ize ndụ nke ịmalite inwe hypoglycemia nwa ebu n'afọ. Dika odi, ojiji nke Gliclazide n'oge inye ara ara.

Ntụziaka na usoro onunu ogwu

Iri mbadamba 30 modified-nke-atọ ga-ewere ya 1 otu ụbọchị kwa nri ụtụtụ. Ọ bụrụ na onye ọrịa enweta ọgwụgwọ a na nke izizi, ọgwụ izizi kwesịrị ịbụ 30 mg, nke a metụtakwara ndị gafere afọ 65. Jiri nwayọ gbanwee dose ahụ ruo mgbe ọ dị mkpa ọgwụgwọ ọ bụla apụta.

A na-atụ aro ịhọrọ ọgwụ ole dabere na ọkwa shuga dị n'ọbara ọbara mmalite nke ọgwụgwọ. Enwere ike ịgbanwe mgbanwe ọ bụla na-esote ya naanị mgbe izu abụọ gachara.

Enwere ike dochie Glyclazide MB na mbadamba Glyclazide na mwepụta nkịtị (80 mg) kwa ụbọchị nke 1-4. Ọ bụrụ na n'ihi ihe ụfọdụ onye ọrịa ahụ ọgwụ ahụ, ọgwụ ọzọ ekwesịghị ịdị elu.

Ọ bụrụ na-eji Glyclazide MB 30 mg mbadamba iji dochie ọgwụ hypoglycemic ọzọ, a gaghị achọ oge ntụgharị na nke a. Ọ bụ naanị na ọ dị mkpa iji mezue ọgwụ kwa ụbọchị nke ọgwụ ị mechara na naanị na-esote ụbọchị ị ga-ewere Gliclazide MB.

Dị Mkpa! Ọ bụrụ na eburu ụzọ jiri ọgwụgwọ mee onye ọrịa ahụ ihe ọmụmụ ogologo oge ọkara, ọ dị mkpa iji nlezianya leba anya itinye glucose na ọbara dị ka izu abụọ.

Nke a dị mkpa iji zere mmepe nke hypoglycemia, nke nwere ike ịpụta megide ndabere nke mmetụta nsị nke usoro ọgwụgwọ gara aga.

Enwere ike ijikọ ọgwụ a na alfa-glucosidase inhibitors, biguanides ma ọ bụ insulin. A na-enye ndị ọrịa nwere obere akụrụ gbasara akwara dị nro ma ọ bụ agafeghị oke, A na-enye Gliclazide MB otu usoro onyonye ndị ọrịa nwere ezigbo ọrụ gbasara ọrụ. Ọgwụ a na contraindicated na nnukwu gbasara akụrụ odida.

Ndị ọrịa nọ n'ihe ize ndụ maka hypoglycemia

Ndị ọrịa nọ n'ihe ize ndụ nke ịmalite hypoglycemia:

1. yana nsogbu na-adịghị edozi ahụ;
2. site na nkwarụ endocrine na-akwụghị ụgwọ ma ọ bụ nnukwu nsogbu (hypothyroidism, adrenal na pituitary insufficiency);
3. na nbipu nke ndị na - ahụ ike hypoglycemic mgbe ha were ogologo oge;
4. ya na udiri obi ojoo nke akwara obi (atherosclerosis, carotid arteriosclerosis, akwara obi);

Maka ndị ọrịa dị otú a, a na-enye ọgwụ Glyclazide MB na obere usoro (30 mg).

Nsonaazụ

Ọgwụ nwere ike ibute glycemia, nke ihe mgbaàmà ndị a gosipụtara:

• mmetụta nke agụụ;
• ike ọgwụgwụ, oke ike;
• isi ọwụwa, nkụda mmụọ;
• ọsụsọ mụbara, ịma jijiji, paresis;
• arrhythmia, palpitations, bradycardia;
• mmụba n'ọbara;
• ehighi ura, ura;
• mgbakasị ahụ, nchekasị, oke iwe, ịda mba;
• mkpasu iwe;
• isi ntị nke ntị;
• mmeghachi omume nwayọ na enweghị ike itinye uche;
• nsogbu uche;
• enweghi ike ịhụ anya;
• aphasia;
• ọnwụ nke njide onwe onye;
• mmetụta nke enweghị enyemaka;
• iku ume;
• ogwe
• delirium;
• ọnwụ, mmụọ.

Mmeghachi omume nfụkasị ahụ:

1. erythema;
2. akpukpo anụ;
3. urticaria;
4. itching nke anụahụ.

Enwere mmetụta ndị dị na ya site na mgbari nri:

• mgbu afọ;
• afọ ọsịsa;
• ọgbụgba, vomiting
• adịkarịghị cholestatic jaundice ịba ọcha n'anya, kama ha chọrọ ọgwụ nkwụghachi ozugbo.

Domebiga ya ókè na inwe mmekọrịta

Site na iji usoro ezughi oke, ohere ị nwere ịmalite hypoglycemic siri ike, nke nwere ike ibute nsogbu akwara ozi, nkwarụ, coma, dị elu. Na mbido mbụ nke ihe iriba ama ndị a, onye ọrịa chọrọ ọgwụ n'ụlọ ọgwụ ngwa ngwa.

Ọ bụrụ na enyo enyo na hypoglycemic coma na-enyo enyo ma ọ bụ chọpụta ọrịa hypoglycemic coma, a ga-enye onye ọrịa ọgwụgwọ 40-50% dextrose. Mgbe nke ahụ gasịrị, ha tinyere mpempe akwụkwọ nwere ihe dextrose 5%, nke dị mkpa iji nọgide na-etinye glucose n'ọbara.

Mgbe onye ọrịa mechara nwetaghachi mmụọ, iji zere hypoglycemia ugboro ugboro, a ga-enyerịrị ya nri nri n'ụdị carbohydrates dị mfe ngwa ngwa. Nke a na-esochi nlezianya banyere ọkwa shuga dị n'ọbara na ilegide onye ọrịa anya na awa 48 na-esote.

Ọ bụ dibia bekee na-ekpebi ime ihe ndị ọzọ, dabere n'ọnọdụ onye ọrịa ahụ. N'ihi ọgwụ akpọrọ na protein ndị na-enye plasma, usoro ọgwụgwọ adịghị arụ ọrụ.

Glyclazide na-akwalite arụmọrụ anticoagulants (warfarin), naanị otu ọnọdụ bụ na enwere ike ịhazigharị ọgwụ ọgwụ anticoagulant.

Danazole yana Gliclazide bụ ọrịa mamịrị. Abụọ n'oge ojiji Danazol na mgbe ọpụpụsịrị, achọrọ nchịkwa glucose na mgbazi nke glycazide.

Nlekọta sistemu nke phenylbutazone na-eme ka mmetụta hypoglycemic nke Gliclazide (ọ na-ebelata ntụgharị site n'ahụ ahụ, na - ekupụ site na mkparịta ụka na protein protein). Achọrọ nlekọta glyclazide na nlekọta glucose ọbara. Ha abụọ n'oge iwere phenylbutazone, na mgbe ọpụpụsịrị ya.

Site na nhazi sistemụ Miconazole na mgbe ị na-eji gel dị n'ime oghere ọnụ, ọ na-eme ka mmetụta hypoglycemic nke ọgwụ ahụ dị, ruo na mmepe nke coma.

Ethanol na ihe omuma ya na-akwalite hypoglycemia, nwere ike iduga mmepe nke hypoglycemic coma.

Mgbe ejikọtara ya na ọgwụ hypoglycemic ndị ọzọ (biguanides, acarbose, insulin), fluconazole, beta-blockers, H2-histamine receptor blockers (cimetidine), angiotensin-na-agbanwe enzyme inhibitors (enalapril, captoprilamide antioxidants, na-abụghị steroidal sulfide inhibitors) Mmetụta hypoglycemic, n'otu n'otu, ihe ize ndụ nke hypoglycemia.

Chlorpromazine na usoro onunu ogwu buru ibu (ihe kariri 100 mg / ubochi) na-abawanye mkpocha glukos n’ime obara, na-egbochi ihe nzuzo nke insulin. Abụọ n'oge eji chlorpromazine, na mgbe ọpụpụsịrị, achọrọ nchịkwa glucose na mgbanwe na dose nke Glyclazide.

GCS (rectal, mpụga, intraarticular, systemic) na-abawanye shuga ọbara na mmepe nke ketoacidosis. Abụọ n'oge eji GCS na mgbe ha wepụtasịrị, a chọrọ njikwa glucose na mgbanwe na dose nke Gliclazide.

Terbutaline salbutamol, ritodrin intravenously - mụbaa shuga ọbara. Achọrọ nchịkwa glucose na n'ọbara ọbara, ọ bụrụ na ọ dị mkpa, a ga-agbanye ọgwụ insulin.

Mkpebi ndị pụrụ iche na ụdị ntọhapụ

Ọgwụ Gliclazide MB dị irè naanị yana jikọtara obere nri kalori, nke nwere obere carbohydrates. Inyocha nlebara anya nke glucose oge niile, na afọ na-adịghị na mgbe nri gachara. Nke a dị ezigbo mkpa na mmalite ọgwụgwọ.

N'oge a na-eji ọgwụ ahụ, iji zere mmerụ ahụ na ihe ọghọm n'okporo ụzọ, a na-atụ aro ka ọ ghara ịkwọ ụgbọala ma jiri usoro ndị dị ize ndụ na-achọ nlebara anya na ọsọ nke mmeghachi omume.

Mpempe 30 mg, ndị a gwakọtara na blister nke 10 iberibe.

Ndụ nchekwa nke Gliclazide bụ afọ 3, emesịa enweghị ike iji ya. Ekwesịrị ịchekwa ọgwụ ọgwụ a kpọrọ nkụ, ọchịchịrị ma dị jụụ, ụmụaka anaghị enweta ya.

Na mpaghara dị iche iche nke mba ahụ, ọnụ ahịa ọgwụ na-akwụ site na 120 ruo 150 rubles. Anyị na-ekwu maka nchịkọta nwere mbadamba iri isii. A na-etinye nkwakọ ngwaahịa na Mkpọ polymer. Otu ite ma ọ bụ 1 ka 6 blisters na-etinye n’ime igbe kaadiboodu.

Ihe dị iche na ọnụahịa dabere na ihe dị iche iche: onye nrụpụta, mpaghara, ọnọdụ ahịa ọgwụ.