Trypsin bụ enzyme protein (enzyme) nke ngalaba exocrine nke pancreas zoro ezo. Na mbu, amuputa onye bu ya uzo na adighi ike, trypsinogen.
Ọ na-abanye duodenum 12, ebe a na-agbanye ya n'ọrụ n'ihi enzyme ọzọ na ya - enterokinase.
A na-ahuta kemịkal chemical nke trypsin dị ka protein. Na omume, ana enweta ya site na ehi.
Ọrụ kachasị mkpa nke trypsin bụ proteolysis, i.e. nkenke nke protein na polypeptides n’ime obere obere - amino acid. Ọ bụ enzyme catalytic.
N’aka ozo, trypsin mebiri protein. A makwaara enzymes ndị ọzọ na-egbu mgbu - lipase, nke na - etinye aka na mgbaze nke abụba, na alfa-amylase, nke na - emebi carbohydrates. Amylase abụghị naanị enzyme pancreatic, a na-agwakọta ya na gland salivary, mana na obere.
Trypsin, amylase na lipase bụ ihe ndị kachasị mkpa na ngịkọ nri. Enweghị ma ọ dịkarịa ala otu n'ime ha, mgbaze nri na-emetụta ya nke ukwuu.
Na mgbakwunye na itinye aka na mgbaze, enzyme trypsin dị irè n'ịgwọ ọrịa dị iche iche:
- na - enyere aka belata mbufụt n’ahụ;
- na-eme ngwa ngwa ọgwụgwọ agwọ, ọnya siri ike;
- nwee ike ikewapụ anụ ahụ nwụrụ anwụ ka ngwaahịa nke necrosis ghara banye n'ọbara ma mee ka egbu egbu;
- na-eme ka ihe nzuzo dị warara, na-eme ka mmiri na-asọ mmiri karịa;
- na - eme ka aefụ nke ọbara na - egbochi;
- na-enyere aka ịgwọ ọrịa nke ọrịa mbufụt fibrinous;
- na-eme ka mwepu nke oke nju;
- na - agwọ ọnya ọgbụgba nke ọnya ọnụ;
Na steeti anaghị arụ ọrụ, onyinye a bụ ihe nchekwa kpamkpam.
Ebe ọ bụ napspsin nwere akụrụngwa na-agwọ ọrịa, a na-eji ya maka imepụta ọgwụ.
Dị ka ọgwụ ọ bụla ọzọ na - arụ ọrụ nke ọgwụ ọ bụla, ojiji nke trypsin nwere ihe ngosi na contraindications maka ojiji.
Mgbe ị na-eji ọgwụ ndị nwere ọgwụ trypsin, aga-ahụta ndụmọdụ nke dọkịta ahụ na ntuziaka maka ị theụ ọgwụ ahụ.
Nkewa trypsin:
- Amorphous - enwere ike iji ya naanị elu (na oke akpụkpọ ahụ).
- Nkịtị - na-abịa n'ụdị nke ntụ ntụ na-acha ọcha-edo edo, na enweghị enweghị isi. A na-eji ya ma nke elu ma maka nchịkwa intramuscular.
Trypsin dị n'okpuru aha dị iche iche: "Pax-trypsin", "Terridekaza", "Ribonuclease", "Asperase", "Lizoamidase", "Dalcex", "Profezim", "Irukson". Ekwesịrị ịchekwa nkwadebe niile na nkụ, ọchịchịrị na-enweghị ọnọdụ okpomọkụ.
Ihe ngosi maka ojiji bu:
- Ọrịa na-efe efe nke ngụgụ na okporo ụzọ (ọnya afọ, oyi baa, njikwa exudative);
- ọrịa bronchiectatic (ọnụnọ nke nnukwu ịgbatị na bronchi);
- oria merụrụ aru na ọnya ọnya na-apụta;
- ọnya na-ala ala nke ntị etiti (otitis media);
- mbufụt nke ihu ihu na elu ala;
- ọnya ụmị ọkpụkpụ (osteomyelitis);
- ọrịa ụbụrụ;
- mgbochi nke kanaal lacrimal;
- mẹ iphe dụ ẹji;
- mgbali ọnya;
- nsogbu n'ihi ịwa ahụ n'anya.
Ihe mgbochi iji ojiji nke trypsin bụ:
- Mmeghachi omume nfụkasị na trypsin.
- Iri ikuku nke ume, mụba ama.
- Ezughị oke ọrụ ọrụ.
- Dystrophic na mkpali na-agbanwe imeju.
- Erkwara nta
- Ọrịa akụrụ.
- Ọrịa akwara na-emegharị ahụ.
- Imebi coagulation na usoro anticoagulation.
- Usoro mmekpa ahụ n’ime akụrụ (jed).
- Hemorrhagic diathesis.
Kedu ihe ọghọm dị na ya mgbe ị jisịrị trypsin?
- allergies
- obi palp;
- acha ọbara ọbara na mgbu mgbe ejiri ọgwụ mgbochi intramuscular;
- ọbara mgbali.
Na mgbakwunye, ịma aka nwere ike ịpụta n'olu onye ọrịa.
Mgbe etinyere ya na elu maka ọgwụgwọ nke ọnya akọrọ ma ọ bụ ọnya nwere anụ ahụ nwụrụ anwụ, a na-eji comppsin impregnated compresses.
Iji mee nke a, ịkwesịrị igbari 50 mg nke enzyme nkwadebe na 50 mg nke salio physiological (sodium chloride, ma ọ bụ 0.9% saline).
A na-ejikarị kpochapụ okpukpu atọ dị iche iche.
Mgbe itinyechara mkpakọ ahụ, a na-etinye ya na bandeeji ma hapụ ya ruo awa iri abụọ na anọ.
Nlekọta intramuscular A na-agwakọta 5 mg nke trypsin na 1-2 ml nke saline, lidocaine ma ọ bụ novocaine. N'ime ndị okenye, a na-eme inje ugboro abụọ n'ụbọchị, maka ụmụaka - naanị otu ugboro.
Iji intraplera mee ihe. Mgbe iwebata ọgwụ ahụ, ị gaghị anọ n'otu ọnọdụ ahụ ogologo oge, n'ihi na nke a na-eme ka o sie ike ịgwagbu ihe nzuzo. Ọtụtụ mgbe, mgbe ụbọchị abụọ gasịrị, ihe nzuzo a na-apụta site na mmiri mmiri.
Ngwa inhalation. A na - ebu ụzọ were adọtị ma ọ bụ klọọkụ. Mgbe usoro ahụ gachara, ọ ka mma iji mmiri ọkụ hicie imi ma ọ bụ ọnụ gị (ọ dabere n'otú esi rụọ usoro ahụ).
Na ụdị anya na-ada. Ọ dị ha mkpa iji mmiri na-asa mmiri kwa awa 6-8 maka ụbọchị 3.
Njirimara nke iji trypsin:
- A machibidoro Trypsin itinye aka na ọnya na-agba ọbara.
- Enweghị ike iji agwọ ọrịa cancer, karịsịa na ọnya anụ ahụ.
- Ejighị ya intravenia.
- Mgbe ị na-elebara ụmụaka anya, a na-ahazi otu atụmatụ.
- Womenmụ nwanyị dị ime ma ọ bụ na-ete nwa kwesịrị ị thisụ ọgwụ a naanị ma ọ bụrụ na ihe ọ bụla dị ọnwụ ya ma ọ bụ ọnwụ nwa ebu n'afọ dị oke mkpa.
Pharmacokinetics, i.e. Emebeghị ịmụ banyere ọgwụ na ahụ. A na - amata na mgbe nkịta batara n'ahụ ahụ, trypsin na - ejikọ alpha macroglobulins na antitrypsin alpha-1 (ihe na - egbochi ya).
Ugbu a, enwere ọtụtụ ọnụọgụ nyocha dị mma banyere ọgwụ ndị nwere trypsin. Karịsịa obosara nke ngwa ya na ophthalmology. Site na ya, ọbara ọgbụgba, adhesions, mkpali na usoro nke ọrịa nke iris ka a na-agwọ, n'ihi na ọrịa ndị a na-enweghị ọgwụgwọ zuru oke nwere ike ibute ìsì na-enweghị mgbagha. Njikọ aka na nhazi nke enzyme na ọgwụ antiallergic, ọgwụ nje, homonụ, ọgwụ glaucoma na-arụ ọrụ nke ukwuu, nke na-eme ka mmụba anụ ahụ dịkwuo elu.
Trypsin nyere aka belata ọrịa ọrịa nkwonkwo, dịka ọrịa ogbu na nkwonkwo, polyarthritis, ogbu na nkwonkwo, na ọrịa rheumatic. Ọ na - ewepụ ihe mgbu, na - egbochi mbufụt, na - eweghachi mmeghari zuru oke.
Site na mmerụ ahụ dị ukwuu, ihe dị omimi, ọkụ, enzyme ahụ na-enye ohere, ntakịrị, iji belata ọdịmma mmadụ niile, wee nwekwuo ọgwụgwọ.
Ọnụ ego nkezi nke nkwadebe trypsin na Russia sitere na 500 rubles.
N'ime ọbara, a na-ekpebi ihe a na-akpọ 'immunoreactive "trypsin yana ihe na-egbochi ihe ọ na-eme - alfa-1-antitrypsin. Ọnụego trypsin bụ 1-4 μmol / ml.min. Mmụba ya nwere ike ịhụba na nnukwu mbufụt nke pancreas, oncological Filiks na ya, ya na cystic fibrosis, ala akụrụ ọdịda, na nwekwara ike na-eso ụzọ nke malitere ịrịa ọrịa. Mbelata nke enzyme ahụ nwere ike igosi ụdị ọrịa shuga 1 bụ ọrịa mellitus, ma ọ bụ ọrịa ndị a dị n'elu, mana n'ụdị na-adịghị ala ala na nke ikpeazụ.
Na mgbakwunye na nyocha ọbara, a na-enyekarị ndị ọrịa usoro nyocha. Tupu ọmụmụ a, a naghị akwado ọgwụ mgbochi 3 maka ụbọchị 3. Mgbe amabataghị trypsin na feces nwere ike ọgaghị achọpụta. Nke a na - abụkarị ihe ịrịba ama nke usoro akwara azụ. A na-ahụta mbelata nke ukwuu na ya na cystic fibrosis, mana nke a apụtaghị na egosipụtara nchoputa ahụ, yana ọmụmụ ihe ndị ọzọ achọrọ iji dokwuo anya. Ugbu a, ekwenyere na mkpebi siri ike nke trypsin na feces na-egosi na ọ nweghị ihe ọ bụla.
Enyere ozi di nkenke banyere trypsin na enzymes ndị ọzọ na vidiyo n'isiokwu a.
