NovoRapid Penfill bụ ihe ejiri ọgwụ akpọrọ akpọrọ hypoglycemic na-arụ ọrụ dabere na insulin aspart. Nke ikpeazụ a dị iche na insulin nke mmadụ site na ọnụnọ nke aspartic acid dị iche na ntụ ọka yist nke ndị na-eme achịcha na-anọchi usoro okwu. Mkpụrụ ndụ a na - egbu egbu belata oge iji nweta nsonaazụ ọgwụgwọ na oge nke ọgwụ, ọ bụ ya mere eji atụ aro ị theụ ọgwụ tupu nri.
International Nonproprietary Aha
Insulin kewaputa.
ATX
A10AB05.
A na-eme ọgwụ ahụ n'ụdị ihe ngwọta maka nchịkwa subcutaneously na intravenously, a na-etinye katriji na ngwugwu ọnya 5 pcs.
Ha weputara udi ya na ihe mebere ya
A na-eme ọgwụ ahụ n'ụdị ihe ngwọta maka nchịkwa subcutaneously na intravenously. N’ile anya, ọ bụ mmiri doro anya, adịghị ọcha na nke enweghị agba. 1 ml nke ọgwụ ahụ nwere 100 IU nke ihe na-arụ ọrụ, nke kwekọrọ na 3500 μg. Dika eji eme ihe ndi ozo:
- glycerol;
- hydrochloric acid;
- sodium hydroxide;
- mmiri mmiri na-egbu egbu;
- phenol;
- zinc na sodium chloride;
- sodium hydrogen phosphate dihydrate;
- metacresol.
Ọgwụ a dị na katriiki iko 3 mil. A na-etinye katalọgụ na ngwugwu ọnya nke 5 pcs.
Omume ọgwụ
Insulin aspart bụ ana ana - ekekọta mmadụ nke mkpụrụ ndụ beta nke pancreas zoro ezo. N'ime usoro mmepụta nke usoro insulin ahụ, a na-eji ọgwụ ntụrụndụ ntụ ntụ dochie proline, wee si ibelata oge iji wee nweta ọgwụgwọ ọgwụgwọ.
NovoRapid Penfill bụ ihe ejiri ọgwụ akpọrọ akpọrọ hypoglycemic na-arụ ọrụ dabere na insulin aspart.
Ihe na - eme ka homonụ ahụ na - emekọrịta ihe yana ndị na - anabata ya nke nọ n’elu elu nke sel ahụ. Site na mkparịta ụka a, e guzobere ogige insulin-receptor nke na-akpali mmepụta nke hexokinase, enzyme nke na-ahụ maka njikọ nke glycogen, na pyruvate kinase.
Mmetụta hypoglycemic bụ n'ihi ịdị ngwa nke metabolic glucose intracellular na nnabata shuga site na anụ ahụ, ịba ụba lipogenesis na usoro glycogen, yana mbelata gluconeogenesis na akwara hepatocytes. Ngwongwo ogwu nke ihe eji aru oru aru dika insulin nke mmadu. Mana n'otu oge ahụ, ọsọ ọsọ iji nweta ihe ọgwụgwọ ọgwụgwọ na NovoRapid Penfill dị elu.
A na - enweta insulin aspart na subcutaneous fatịlaịza nke dermis na subcutaneous nchịkwa ngwa ngwa ma rute mmetụta hypoglycemic n'oge dị mkpirikpi karịa insulin na -akpata mmadụ.
Mlọ ọgwụ
Site na ntinye nke NovoRapid subcutaneously, oge iji ruo n'ọbara plasma kachasị n'ọbara belata ugboro abụọ ma e jiri ya tụnyere nchịkwa ọkọlọtọ nke insulin insulin. A na-edekọ ụkpụrụ dịkarịrị ala n'ime nkeji iri anọ mgbe inyechara ịgba ntụtụ ahụ. Ntinye insulin n'ime ọbara na-alaghachi n'ụkpụrụ mbụ ya mgbe awa 4-6 gachara ị administrationụ ọgwụ ahụ. N'ime ndị ọrịa nwere ọrịa mellitus nke na-abụghị insulin, mmịnye a na-agbadata dị ala, ọ bụ ya mere oge iji ruo ogo ịta ọkwa plasma kachasị nke aspart insulin rutere minit 60.
Ihe ngosi maka ojiji
A na-eji ọgwụ ahụ eme ihe iji nweta njikwa glycemic ma mesoo shuga ọbara n'ọdịrị nke ụdị 1 na ụdị shuga 2. N'okwu nke abụọ, a na-ewepụ ọgwụ ahụ na mmepe nke nguzogide ọgwụ mgbochi hypoglycemic zuru oke. Mgbachi ihu na-achọ nnabata nke NovoRapid na usoro njikọta ọgwụ.
Amachibidoro ọgwụ NovoRapid iwu maka ụmụaka erughi afọ abụọ.
A na-eji ọgwụ ahụ eme ihe mgbe ọ na-agaghị ekwe omume ịnye ọgwụ ndị ọzọ hypoglycemic megide ndabere nke mmepe nke ọrịa intercurrent - usoro pathological gbagwojuru anya site n'ọdịdị nke ọrịa nke abụọ.
Ihe ngbanwe
Amachibidoro ọgwụ a kpamkpam na ọnụnọ hypoglycemia na ụba ịba ụba na mpaghara ahụ nọ n'ọrụ, ụmụaka na-erubeghị afọ abụọ.
Jiri nlezianya
Ọ na-atụ aro ịkpachara anya maka ndị nwere ọrụ imeju na-ezighi ezi, na ọnụnọ neoplasms ọjọọ, yana maka ndị okenye karịa afọ 65.
Etu esi ewere NovoRapid Penfill?
A na-achịkwa ọgwụ ahụ subcutaneously ma ọ bụ intravenously. A na-ekpebi usoro ọgwụ kwa ụbọchị nke NovoRapid na dibia bekee na-eleta anya dị iche iche dabere n'ọkwa shuga yana ihe ịchọrọ kwa ụbọchị maka insulin. A na-atụ aro ka ị tinye ọgwụ ahụ na ọgwụ njikọta yana ọgwụ hypoglycemic nke obere oge ma ọ bụ ogologo oge, nke a na-ewere otu ugboro n'ụbọchị.
Iji mezuo nchịkwa glycemic dị mkpa, ọ dị mkpa ịgụta ndị na-egosi glucose ọbara ugboro ugboro, dabere na nke usoro ga-esi dozie ya.
Etu esi egbu ntụtụ?
Can nweghị ike ịbanye ọgwụ ahụ intramuscularly. A na-atụ aro ka ịgbanwe mpaghara ịgba ọgwụ na ntụtụ ọ bụla iji belata ohere nke akàrà na ọnya a.
Site na ọgwụgwọ onwe, a na-edozi insulin subcutaneously. A na-eme ọgwụ infusion IV n'okpuru nlekọta nke ọkachamara ahụike. Iji mezuo ntụtụ, ọ dị mkpa ịgbaso algorithm etolite:
- Okwesiri ijide agịga n'okpuru anụ ahụ ọ dịkarịa ala 6 sekọnd site na ịpị bọtịnụ mmalite (a na-ahapụ ya mgbe ewepụchara agịga). Usoro a ga - ewepụta nchịkwa insulin nke 100% ọ ga - egbochi ọbara ịbanye na katriiki.
- Ọ bụ naanị maka iji naanị otu oge. Site na nchịkwa insulin ugboro ugboro site na otu agịga, ihe ngwọta nwere ike ibupu site na katriiki, n'ihi nke ahụ ga-anata ọgwụ homonụ na-ezighi ezi.
- Ejikwala katrij.
Ọ na-atụ aro ka ị were gị oge injin ma ọ bụ mebie nke igwe mgbe ọ bụla.
Ọrịa mamịrị
Mkpa insulin kwa ụbọchị maka ndị ọrịa na ụmụaka toro eto si na ọgwụ ọgwụ 0,5 ruo 1 kwa kilogram dị arọ. Site na ntinye ọgwụ tupu iri nri, anụ ahụ na-enweta 50-70% nke ọgwụ achọrọ nke homonụ a na-eme ka ọ bụrụ pacenti. Ahụ ike ma ọ bụ ọgwụ ndị ọzọ na-eji nwayọ arụ ọrụ ejupụta. Site na mmụba na mmega ahụ, mgbanwe nke nri, ọnụnọ nke ọrịa nke abụọ, idozi usoro iji usoro ọgwụgwọ dị mkpa.
Insulin aspart, n’adịghị ka insulin na -akụ mmiri, nwere nnukwu ọsọ na obere mkpụmkpụ, yabụ a na-atụ aro ịnye ọgwụ ahụ tupu nri. N'ihi ntakịrị oge nke ime ihe, enwere ike belata hypoglycemia n'abalị.
Maka nchịkwa intraven dị na ọnọdụ, ọ dị mkpa ịkwadebe dropper.
Maka nchịkwa intraven dị na ọnọdụ, ọ dị mkpa ịkwadebe dropper. Nkwadebe nke infusion gụnyere na diling 100 UNITS nke NovoRapid na 0.9% isotonic ngwọta nke Sodium chloride nke mere na itinye uche nke insulin na-adị iche na 0.05 ruo 1 UNITS / ml.
Mmetụta ọghọm NovoRapida Penfill
Nsonaazụ ndị ọzọ na-etolite n'ọtụtụ oge n'ihi usoro ntụtụ adịghị mma. Iji belata ihe ize ndụ nke hypoglycemia, ọ dị mkpa iji họrọ kpọmkwem ọgwụ NovoRapid.
Site na usoro ahụ ji alụso ọrịa ọgụ
Ikekwe ọdịdị urticaria, rashes na anụ ahụ, mmeghachi mmeghachi omume anaphylactic.
N'aka nke metabolism na nri
Nnukwu ihe egwu hypoglycemia nwere usoro na-adịghị mma.
Sistemụ akwara Central
N'ọnọdụ ndị a na-adịghị ahụkebe, akwara polyneuropathy na-enwe nsogbu n'akụkụ.
Na akụkụ ahụ nke ọhụụ
Mmetụta anya na-egosipụta onwe ya na nkwarụ nkọ ma ọ bụ mmepe nke ọrịa mamịrị retinopathy.
Site na sistem iku ume
N'ụfọdụ, nku ume adịghị adị.
Na anụahụ
Ikekwe mmepe nke lipodystrophy.
Ahụhụ
N’ọnọdụ ndị pụrụ iche, enwere nsogbu nke oke ara, tinyere rashes na itching, afọ mgbu, ịsụsọ ịba ụba, edere Quincke, tachycardia, hypotension. Mmeghachi omume anaphylactoid na-egbu onye ọrịa ọrịa.
Mmetụta ikike ịchịkwa usoro
Site na mfu nke njikwa glycemic, yana hypoglycemia ma ọ bụ hyperglycemia, ikike itinye uche na-emebi emebi na ọsọ nke mgbanwe. Nke a nwere ike bụrụ ihe dị ize ndụ mgbe ị na-anya ma ọ bụ na-ejikwa igwe mgbagwoju anya.
Inweta NovoRapid Penfill nwere ike dị ize ndụ mgbe ị na-anya ụgbọala.
Ntụziaka pụrụ iche
Site na iji obere insulin ma ọ bụ wepụ ọgwụ, obere mmepe nke hypoglycemia na ketoacidosis nwere ike ime megide mmalite nke mmụba nke anụ ahụ ketone na shuga na plasma ọbara, karịsịa ndị ọrịa nwere ụdị ọrịa shuga 1 nke ọrịa mellitus. Hyperglycemia nwere ike ime nke nta nke nta mgbe otu izu gachara. Ihe mgbaàmà mbụ nke mmepe nke usoro pathological ga - abụ:
- ọnụ kpọrọ nkụ
- iro ụra
- acha ọbara ọbara na anụ ahụ;
- polyuria;
- oké agụụ;
- ọgbụgbọ, ọgbụgbọ, na akpịrị ịkpọ nkụ;
- isi acetone si n'ọnụ ya.
Otu ihe dị na ụlọ ọgwụ ọgwụ insulin na-eme ihe ngwa ngwa bụ mmepe ngwa ngwa nke hypoglycemia, n'ụzọ dị iche na insulin na -akpata mmadụ.
N'ebe ndị ọrịa nwere ọria imeju na akụrụ ọrụ, a na-ebelata ọnụego nnabata insulin aspart.
Jiri n'oge ime na lactation
N'ime omumu ihe omumu banyere umu anumanu, insulin aspart gosiputara enweghi oria na teratogenicity. Mgbe ha na-ede akwụkwọ NovoRapid, ọ dị ụmụ nwanyị dị ime mkpa ịdị na-elele glucose plasma nke ukwuu. Dọkịta kwesịrị inyocha ọnọdụ ndị ọrịa.
N'ime oge izizi nke utoyonia na n’oge ọrụ, mkpa insulin na-ebelata, ebe n’ime oge nke abụọ na nke atọ usoro ike nke nwayọ na-abawanye.
N'oge a na-enye nwa ara, ọ dị mkpa ịgbanwe usoro nke insulin.
Mmanya ndakọrịta
Ethanol kwalite mmetụta hypoglycemic nke insulin aspart; yabụ, ị alcoholụ mmanya na-egbu n'oge oge ọgwụ a machibidoro iwu. Mmanya ethyl nwere ike iduga mmepe nke hypoglycemia na hypoglycemic coma.
Nwepu nke NovoRapida Penfill
Hypoglycemia nwere ike ịmalite nke nta nke nta na nzụlite usoro nchịkwa ogologo oge nke nnukwu ọgwụ NovoRapid. N'okwu a, ọnụọgụ ọgwụ nke nwere ike ime ka onyonyo a na-ahụ maka nnabata emebebeghị, n'ihi na hypoglycemic steeti na-egosipụta onwe ya dabere na njirimara onye ọrịa ahụ.
Ọrịa hypoglycemia dị ala, onye ọrịa ahụ nwere ike iwepụ n'onwe ya site na iwepụta ngwaahịa nwere nnukwu shuga ma ọ bụ glucose dị n'ime.
Ọbara hypoglycemia na-esochi ọnwụ nke mmụọ. N'okwu a, ụlọ ọgwụ, iwebata intramuscularly ma ọ bụ subcutaneously 0,5-1 mg nke glucagon. A na-anabata ntinye nke ngwakọta glucose na-anabata. Ọ bụrụ na mgbe nkeji iri na ise nke 10-15 gachara Glucagon, nsụhọ alaghachighi, ị ga-abanye 5% nke Dextrose. Mgbe ị na-eweghachi ọnọdụ ahụ ma na-eteta onye ọrịa, ọ dị mkpa iji nri ndị nwere nnukwu carbohydrates na-enye onye ọrịa ahụ. Nke a dị mkpa iji gbochie mmepe nlọghachi.
Ọbara hypoglycemia na-esochi ọnwụ nke mmụọ.
Mmekọrịta na ọgwụ ndị ọzọ
Drugsfọdụ ọgwụ nwere ike ịkwalite mmetụta hypoglycemic nke NovoRapid:
- monoamine oxidase, ACE inhibitors, carbon anhydrase inhibitors;
- ọgwụ ndị nwere lithium;
- ndị na - achọghị beta-mgbochi;
- sulfonamides;
- Fenfluramine;
- oge ndị ethanol nwere na hypoglycemic jami;
- Bromocriptine;
- ọgwụ mgbochi tetracycline;
- Octreotide;
- Pyridoxine.
A na - ahụbe mmebi nke ọgwụgwọ ahụ site na oge nchịkwa nke NovoRapid nwere mgbochi mgbochi calcium, diuretics, Heparin, antidepressants, glucocorticosteroids, Morphine, na ndị ọrụ nwere homonụ thyroid.
Reserpine na salicylates nwere ike ịkpata ọnwụ nke njikwa glycemic.
Smụ sịga n'ihi ọdịnaya nke nicotine nwere ike belata mmetụta hypoglycemic.
Ọgwụ Thiol nwere ọgwụ sulfite mgbe ị na-emekọ insulin na-ebute mbibi nke ndị ikpeazụ.
Analogs
Ana Structure analogues na ọgwụ nwere otu ọgwụ kemịkalụ na-agụnye:
- Arụ Ọrụ;
- Pen NovoRapid sirinji;
- Apidra
- Biosulin;
- Gensulin;
- Insulin.
Ahịa ọgwụ na-ahapụ okwu
A na-ere ọgwụ ahụ maka ebumnuche ọgwụ.
Enwere m ike ịzụta na ndenye ọgwụ?
Ihe nnọchianya nke glycemic, ma ọ bụrụ na ejiri ya mee ihe na-adịghị mma, nwere ike ịkpasu hypoglycemia, nke nwere ike ịmalite ịghọ mmiri hypoglycemic. Ọnọdụ a dị ize ndụ, yabụ amachibido iji ọgwụ a na-enweghị ndenye ọgwụ.
Ọnụahịa maka NovoRapid Penfill
Onu ogugu nke ubochi ahia bu 1850 rubles.
Ọnọdụ nchekwa maka ọgwụ
Ọ dị mkpa ịchekwa ọgwụ ahụ na okpomọkụ nke + 2 ... + 8 Celsius. A na-atụ aro idobe ya na friji, mana enweghị ike kpọnwụrụ. Ekwesiri idowe nri ndi ozo n’ime kaadiboodu iji chebe ha site n’onwu. A na-echekwa katridges emepere na okpomọkụ nke + 15 ... + 30 Celsius C ma jiri ya rụọ ọrụ otu ọnwa.
Analog nke ọgwụ ahụ nwere ike ịbụ ọgwụ Apidra.
Bọchị mmebi
30 ikp
Emeputa
Novo Nordisk A / S, Denmark.
Nyocha maka NovoRapida Penfill
N'ime oge azụmaahịa, insulin aspart tụrụ aka na mmetụta ya n'ahịa ọgwụ, n'ihi nke a na-ekwu okwu dị mma sitere na ndị ọrịa na ndị dọkịta na ntanetị.
Ndi dibia
Zinaida Siyuhova, endocrinologist, Moscow.
Ọgwụ nwere obere ihe dị mkpụmkpụ, na-enye gị ohere ịbanye insulin ọ bụghị naanị minit 10-15 tupu nri, kamakwa n'oge nri na mgbe ị gachara. Nrụpụta ọgwụgwọ ngwa ngwa nke ọgwụgwọ ọgwụgwọ dị mkpa n'ọnọdụ ọnọdụ mberede. Site na insulin aspart, onye nwere ụdị ọrịa shuga mellitus nke 2 ma ọ bụ ọrịa shuga insulin na-enweghị ike ịnagide ọrịa, mezie nri ahụ ọ chọrọ.
Ignatov Konstantin, endocrinologist, Ryazan.
Dị ka ihe insulin wepụrụ. N'ọnọdụ ndị siri ike, ọ na-enyere aka belata glucose ọbara ngwa ngwa.N'otu oge ahụ, onye ọrịa ahụ ga-agbaso usoro ọgwụgwọ ahụ dabere na ntuziaka ndị ahụ si dị, ma ọ bụghị ihe egwu nke ịmalite hypoglycemia na-abawanye. Onye ọrịa ahụ nwere ike iji aka ya mee ka ọgwụ insulin na-abanye n’onwe ya.
Ndị ọrịa
Artemy Nikolaev, 37 afọ, Krasnodar.
Enwere m ọrịa shuga 1 kemgbe m dị afọ 18. Akwụ ụgwọ Actrapid, nke enyereghị aka inweta njikwa glycemic - shuga ka dị elu. Dọkịta dochiri Actrapid na ọgwụgwọ njikọta na NovoRapid Penfill na-eme mkpụmkpụ oge na ogologo oge Levemir. NovoRapid dabara n’arụ m. Ana m ekele onye mepụtara ya maka insulin mara mma.
Sofia Krasilnikova, 24 afọ, Tomsk.
Anọwo m na-eji katridges ruo ihe karịrị otu afọ. Ọkwa shuga dị n’agbata oge ị na-aga. Ozugbo ọ biliri, m na-eche ozugbo. Na minit 10-15, laghachiri na nkịtị. Ahụghị m mmeghachi omume ọ bụla.
