Ọgwụ Movogleken: ntuziaka maka ojiji

Movoglechen bụ usoro nke abụọ a na-akpọ sulfonylurea nke nwere mmetụta hypoglycemic n'ahụ. Usoro ihe a na-eme bụ ịbawanye uru nke akwara ndị dị na insulin yana iwelie mkpụrụ ndụ homonụ nke sel beta pancreatic. N'ime usoro ahụike, a na-enye ọgwụ hypoglycemic maka ọrịa shuga 2. Amachibidoro iji shuga na-arịa insulin.

International Nonproprietary Aha

Glipizide. Na Latin - Glipizide.

Ọgwụ Movoglecen nwere aha aha mba ụwa bụ Glipizide.

ATX

A10BB07.

Ha weputara udi ya na ihe mebere ya

A na-eme ọgwụ ahụ n'ụdị usoro nke mbadamba ọcha. N’akụkụ akụkụ nke ọgwụ ọgwụ ahụ, a na-ese ihe ize ndụ, ebe a na-ahụ mkpụrụ akwụkwọ leta “U” dị na okirikiri ahụ site na ntụgharị. Tabletdị mbadamba 1 nwere 5 mg nke ogige arụ ọrụ - glipizide. Iji mee ka mmụba na bioavailability dịkwuo elu, okpokoro mbadamba nwere ihe ndị ọzọ:

• pregelatinized stachi;
• hypromellose;
• mmiri ara ehi shuga;
• acid stearic;
• microcrystalline cellulose.

Mbadamba ahụ nwere akụkụ gburugburu cylindrical, kpuchie ya na ọkwa ikpeazụ nke mmepụta site na ihe nkiri ahụ. Nke ikpeazụ a bụ talc, titanium dioxide, macrogol. A na-etinye mkpụrụ ọgwụ ọgwụ na ọnya ọnya nke iberibe 24. N'ime igbe katọn dị mbadamba 48.

Omume ọgwụ

Ọgwụ ọgwụ hypoglycemic bụ ọgwụ sitere na sulfonylurea.

Ọgwụ Movoglechen na-emetụta ọrụ nke pancreas ma n'otu oge ahụ na-enwe mmetụta na-egbochi pancreatic.

Ngwaọrụ eji arụ ọrụ bụ nke ọgbọ II. Usoro nke ihe na - arụ ọrụ na - arụ ọrụ na - emetụta ọrụ nke pancreas ma n'otu oge ahụ na - enwe mmetụta na - emeju. Glipizide na-arụ ọrụ nke imepụta insulin site na mkpụrụ ndụ beta nke pancreatic n'oge mgbakasị anụ ahụ site na glucose, na-eme ka ike nke anụ ahụ nwee mmetụta hypoglycemic nke hormone ahụ.

N'ime usoro iji nweta nsonaazụ ọgwụgwọ, ogige a na-arụ ọrụ na-eme ka ohere nke ịulinụ insulin ọgụ na mkpụrụ ndụ kwụsị, na-eme ka ntọhapụ nke homonụ a na-eme ka a na-anyụ ọrụ. N’ihi nke a, a na - eme ka mmetụta insulin n'ahụ ụmụ irighiri glucose dịkwuo elu, na ogo ogosi ịnabata shuga site n’ọkpụkpụ akwara na hepatocytes. Enwere mbelata gluconeogenesis na imeju na ogwe egbugbere ọnụ na anụ ahụ adipose.

Ogo nke mmetụta ọgwụgwọ na-adabere na ọnụọgụ beta mkpụrụ ndụ nke pancreas.

Ọgwụ ọzọ nwere mmetụta nke fibrinolytic, diuretic na lipid, na-egbochi nrapado platelet, nke na-esote inwe njikọ ọbara.

Movoglechen na-egbochi nnabata platelet, ntinye nke thrombus sochiri.

Mlọ ọgwụ

Mgbe ejiri ya, onye na-ahụ maka hypoglycemic na-ahụ maka ọnya na-abanye kpamkpam na mgbidi nke obere eriri afọ proximal na oke ọsọ.

Iri nri ugbu a anaghị ebute mgbanwe na ọgwụ ọgwụ. N'okwu a, oge nnabata na-abawanye site na nkeji iri anọ na ise. Mgbe a gbasasịrị ọgwụ ahụ n'usoro sistemu sistem, enwere ike idozi ọkwa plasma kachasị n'ime elekere 1-3 mgbe ejiri otu mbadamba.

Bioavailability nke glipizide ruru 90%. N'ime ọbara, akụrụngwa nọ n'ọrụ na-ejikọ albumin site na 98-99%. Mgbe glipizide na-agafe hepatocytes, a na-arapara n'ihe ahụ na-arụ ọrụ na metabolic na-anaghị egosipụta ọrụ hypoglycemic. Iwepu ọkara ndụ na-eme awa 2-4. Akara ọgwụ ahụ 90% n'ụdị metabolites site na akụrụ, 10% n'ụdị mbụ ya.

Ihe ngosi maka ojiji

Mbadamba ụrọ Movoglechen nwere ike belata plasma nke glucose n'ụdị shuga nke abụọ ma ọ bụrụ na anaghị agwọ ọrịa shuga na-enweghị insulin na usoro nri, mmega ahụ na usoro ndị ọzọ iji belata oke ibu.

Ihe ngbanwe

Amachibidoro ị medicationụ ọgwụ n'ọnọdụ ndị a:

• ekwuputara nnomi akwara nke anụ ahụ na sulfonamides, glipizide, ihe ndị ọzọ Movogleken ma ọ bụ usoro nke sulfonylurea;
• ụdị 1 ọrịa shuga mellitus;
• enweghị nkwekọrịta nke lactose, ọrịa glucose na ụyọkọ galactose, ụkọ lactase;
• okpukpo oku na ịwa ahụ nke akụkụ dị iche iche nke ihe, ọnọdụ ọjọọ mgbe ọnya na-akpata ma mmerụ ahụ, usoro na-efe efe na mkpali;
• ọrịa mamịrị na hyperosmolar coma, steeti precomatous;
• ketoacidosis;
• ọrịa siri ike nke imeju na akụrụ.

Ejila Movoglechen maka ndi nwere oria 1.

A machibidoro ọgwụ a na ntinye aka na ọtụtụ ihe eji eme ya.

Ọzọkwa, ejighị Movoglecen maka ọrịa imeju siri ike.

Ọ dị mkpa iji ọgwụ jiri nlezianya nyochaa ọnọdụ nke ihe mgbapụta ndọrọ ndọrọ, ndị nwere nsogbu adrenal, ya na leukopenia, ahụ ọkụ na mmebi nke thyroid gland, yana mgbakasị ahụ na-egbochi ya homonụ.

Uzo esi ewere Movoglechen

Usoro ọgwụgwọ ọkaibe na-eme ka usoro ọgwụgwọ ahụ dabere na ogo anụ ahụ yana afọ onye ọrịa, yana njiri mara usoro pathological.

Dọkịta nwere ike ịme mgbanwe na usoro dosing nwere mgbanwe siri ike na ọkwa glucose ọbara.

Ya mere, iji nlezianya leba anya ịbanye n'ọbara shuga dị mkpa: egosi na afọ efu na mgbe awa 2 gachara.

Na-arịa ọrịa shuga

Mbadamba dị mkpa maka nchịkwa ọnụ nkeji 30 tupu nri. N'ụtụtụ tupu nri ụtụtụ, ị ga-anara 5 mg nke ọgwụ ahụ, na-enweghị mmetụta ọgwụgwọ, mee ka ọgwụ ahụ dịkwuo elu site na 2.5-5 mg, dabere na ndidi.

Oke na-anabata ohere kwa ụbọchị nke Movoglek bụ 40 mg, usoro onunu ogwu maka otu oge bu 15 mg.

Oke kachasị akwadoro kwa ụbọchị bụ 40 mg, usoro onunu ogwu maka otu eji eme ihe bu 15 mg. Mbadamba kwesịrị ị drunkụ mmanya 1 oge kwa ụbọchị. Site n'ụkpụrụ kwa ụbọchị dị elu karịa 15 mg, ọ dị mkpa iji kee usoro onunu ogwu n'ime usoro onunu ogwu 2-4.

Nsonaazụ Movoglyken

Mmetụta ikike ịchịkwa usoro

Ọgwụ hypoglycemic adịghị emetụta sistemu akwara na njikwa ike dị mma, yabụ n'oge ọgwụgwọ a machibidoro ya ịkwọ ụgbọ ala ma ọ bụ rụọ ọrụ na ngwaọrụ dị mgbagwoju anya nke chọrọ nzaghachi ngwa ngwa na itinye uche siri ike.

N’oge a na-agwọ Movogleken, amachibidoro ya ịkwọ ụgbọ ala.

Ntụziaka pụrụ iche

A na-edozi usoro ọgwụgwọ ahụ n'ọnọdụ nke nrụgide na-enye aka na ọnwụ nke mmụọ mmetụta uche, na ọnọdụ nke mgbalị anụ ahụ, yana mgbanwe na nri.

Mgbe ị na-edekọ ọrịa shuga na-enweghị insulin na mgbe ị na-edepụta ọrụ ịwa ahụ, ọ dị mkpa ịkpọtụrụ dọkịta gị gbasara usoro iji dochie insulin.

Tupu o depụta onye na-ahụ maka hypoglycemic, a ga-agwa onye ọrịa ahụ na ohere nke ịmalite hypoglycemia na ọrịa mamịrị na-abawanye mmanya na mmanya, ọgwụ mgbochi mkpali na - enweghị steroidal, na ike ọgwụgwụ ogologo oge. Mgbe ị na-a beụ ihe ọholicụ alcoụ na-aba n'anya, mmeghachi omume disulfiram nwere ike ime, nke a na-egosipụta mgbu afọ, ọgbụgbọ, na ọgbụgbọ.

Iji belata ihe ize ndụ nke hypoglycemia n'ihi ọrịa na-efe efe, a ga-eji ngwaahịa ịdị ọcha iji gbochie nke ikpeazụ.

Site na iji Movoglecen ruo ogologo oge, ọ ga-ekwe omume ịzụlite iguzogide ihe ọgwụ ahụ na-esochi ike nke ọgwụgwọ. N'okwu a, a na-atụ aro ịbawanye usoro ị dailyụ ọgwụ kwa ụbọchị ma ọ bụ iji dochie onye nnọchi anya hypoglycemic.

Amachibidoro ọgwụ a maka ụmụaka na-erubeghị afọ 18.

Inye umuaka

Amachibidoro ọgwụ a maka ụmụaka na-erubeghị afọ 18 n'ihi na enweghị ozi banyere mmetụta nke glipizide na uto na mmepe nke ahụ mmadụ na nwata.

Jiri n'oge ime na lactation

Amaghị etu esi arụ ọrụ kemikal nọ n'ọrụ nwere ike imetụta usoro mmepe nwa ẹmbrayo. O nwere ike isi banye na glipizide site na mgbochi mgbochi nke usoro mmamiri nke ihe agha. Na njikọta echiche ndị a, a machibidoro ụmụ nwanyị dị ime iji ọgwụ hypoglycemic maka nchịkwa ọnụ.

A na-atụ aro iji katridges nwere insulin mmadụ iji belata ọkwa glucose.

N'oge ọgwụgwọ Movogleken, ọ dị mkpa ịnyefe nwatakịrị ahụ ka ọ bụrụ nri na-enweghị isi ma kwụsị inye ya ara.

N'oge ọgwụgwọ Movogleken, ọ dị mkpa iji nyefee nwatakịrị ahụ nri na-edozi ahụ.

Ngwa maka ọrụ ezughi oke ọrụ

N'ime ọrịa akụrụ siri ike, ị prohibitedụ ọgwụ a ka amachibidoro, n'ihi na ọgwụ ahụ dị na mmamịrị.

Jiri maka ọrụ imeju na-arụ ọrụ

Ọ dị mkpa ijikwa ọrụ umeji yana enzymes ya na ogo nke oke ezughi oke. Ọnụnọ nke usoro ịkpọasị nje, amachibidoro ọgwụ ọgwụ ọgwụ.

Dodoụbiga mmanya ókè nke Movoglyken

Ofụbiga ọgwụ ike ókè nwere ike ibute hypoglycemia. Ọnọdụ a jikọtara:

• mmetụta nke agụụ agụụ;
• ọnọdụ mberede na-ewere oke iwe na ọnọdụ iwe;
• ịsụsọ ọnụ;
• ihe ịtụnanya nke ọnọdụ ịda mba;
• ehighi ura;
• hypoglycemic coma;
• nkwarụ okwu na anya;
• isi ntị nke ntị;
• ọnwụ nke mmụọ.

Useụbiga ọgwụ ike ókè nwere ike ime ka ọsụsọ dịkwuo ukwuu.

Ọ bụrụ na onye ọrịa ahụ maara, ọ dị mkpa inye ya ọgwụ shuga. Ọ bụrụ na mmụọ amaghị, ekwesịrị idozi 40% dextrose solution intravenly ma ọ bụ onye a ga-eji mmiri mmiri 5% tinye glucose. A na-edozi 1-2 mg nke glucagon subcutaneously. Mgbe emegharia steeti mgbe onye ọrịa nwetaghachiri onwe ya, o kwesịrị iri nri oke na carbohydrates. Nke a dị mkpa iji gbochie ịmaliteghachi hypoglycemia. Site na ụbụrụ ụbụrụ, a chọrọ ọgwụgwọ na Dexamethasone ma ọ bụ Mannitol.

Mmekọrịta na ọgwụ ndị ọzọ

A na - ahụta ọgwụ inyonye ọgwụ na miconazole.

Movoglecen na-ebelata ọgwụgwọ ọgwụgwọ nke furosemide.

Ojiji nke ọgwụ myelotoxic na-abawanye ohere nke agranulocytosis, nwere ike ịkpalite ọdịdị nke thrombocytopenia.

Mmanya ndakọrịta

Mmanya Ethyl na-akwalite mmetụta hypoglycemic, na-egbochi sistemu hematopoietic, ọrụ imeju ma na-eme ka ohere nke ọbara sie ike n'ihi ịba ụba nke mkpụrụ ndụ ọbara uhie na platelet. Ethanol na-emetụta usoro akwara dị ala na trophism nke anụ ahụ, ya mere, ọ dị mkpa ịhapụ ị ofụ mmanya maka oge nke Movogleken.

Analogs

Nwere ike dochie ọgwụ a otu n’ime ọgwụ ndị a:

• Glenez;
• Glibenesis;
• Antidiab;
• Ọrịa mamịrị.

Ahịa ọgwụ na-ahapụ okwu

A na-ere ọgwụ hypoglycemic site na ndenye ọgwụ.

Enwere m ike ịzụta na ndenye ọgwụ

N'ihi ihe ize ndụ nke ịmalite ọrịa hypoglycemic coma, amachibidoro iji ọgwụ ahụ n'onwe ya na-enweghị ndụmọdụ ahụike.

Ọnụahịa maka Movoglechen

Ọnụahịa dị elu na ahịa ọgwụ rutere 1,600 rubles.

Ọnọdụ nchekwa maka ọgwụ

Ọ na-atụ aro idobe mbadamba nkume ahụ n'ebe na-anọpụ iche site na ọnya UV na-enwe okpomọkụ nke + 8 ... + 25 Celsius

Bọchị mmebi

42 ọnwa.

A na - echekwa ọgwụ ana - eme Movogleken - Diabeton ọgwụ na ebe a na - anọpụ iche na ọnya UV.

Emeputa

Zhuhai United Laboratories Co., China.

Nyocha nke Movogleken

Kristina Doronina, afọ 28, Vladivostok

Di m nwere ọbara mgbali elu. Ruo ọtụtụ afọ, ha enweghị ike ịchọpụta ihe kwesịrị ekwesị glycemic na-elekọta mmadụ, nke mere na ọ bụghị naanị iji belata shuga, kamakwa iji debe ọnụego n'ime oke. N'ime oge ọzọ ha na-eme, edebere mbadamba mkpụrụ osisi Movoglecen. Mgbe ụbọchị 30 nke ọgwụgwọ, shuga laghachiri na nkịtị, ọgwụ wee gbagote. Ugbu a ọ dị n'ime 8.2 mm, mana ọ dị mma karịa 13-15 mm, nke dị na mbụ.

Yaroslav Filatov, 39 afọ, Tomsk

Ọgwụ ahụ enyereghị aka na mbido. Mgbe itinye 5 mg n'ụtụtụ, shuga dị n'ime 10-13 mm, ọnya ahụ malitere. Site na mmụba na dose ruo 20 mg, glucose ji nwayọọ nwayọọ belata na izu abụọ ruo 6 mm. Nsonaazụ rụpụtara onwe ha. Mana ihe ngosi a dabere na nri na ntinye n’ime ntuziaka ahụ. Ọgwụ enweghị ike belata shuga n'ihe banyere nsogbu na-edozi ahụ.

Ulyana Guseeva, onye gbara afọ 64, Krasnoyarsk

Mgbe ọ dị afọ 62, shuga ọbara ruru 16-18 mm. Ọ malitere n'oge opupu ihe ubi, mgbe ọ lara ezumike nká. Ọ malitere iduzi ibi ndụ nkịtị n'ihi enweghị ọrụ, nke dugara n'ọbara glucose n'ọbara. Ejikọtara Gluconorm na Siofor.Mbadamba ụrọ Movoglek. Ugboro abụọ jiri shuga belata. N’okpuru ebe 8 mm anaghị ebelata. Achọpụtabeghị m ihe ọ bụla na-akpata. Ka ọ dị ugbu a, ọ na-agbake, mana ọ bụrụ na ọ ka njọ, ọ ga-aka mma ka ọ gaa ọgwụ ọzọ.