Acidosis bụ ihe na-agagharị na acid - nguzozi ala maka mmụba nke acidity. Nke a bụ n'ihi mkpo nke acid acid na ọbara.
Acidosis na-arịa ọrịa shuga na-apụtakarị na mkpo nke anụ ketone - ketoacidosis. Ọzọkwa, na-abawanye na ịta nke lactic acid n'ime ọbara, lactic acidosis nwere ike ime.
Typesdị abụọ a tolitere na usoro ịba ọcha n'anya ma chọọ ụlọ ọgwụ ozugbo, ebe ọ bụ na mmụba nke ihe mgbaàmà acidosis na-eduga Coma.
Ihe kpatara ketoacidosis na ọrịa shuga
Ebe ụkọ insulin dị na sel, ihe na-ebute ụnwụ nri bụ n'ihi enweghị glucose. Maka ume, anụ ahụ na-amalite iji nchekwa nke abụba. Abụba, mgbe etisasịsịrị, na-akpụ ahụ ketone - acetone, acetoacetic na beta-hydroxybutyric acid.
Ketones sitere na ọbara na-apụ apụ na mmamịrị ahụ, mana ọ bụrụ na etinyere ọtụtụ, akụrụ akaghị enwe ike ịnagide ibu ahụ yana acidity nke ọbara na-ebili. Ọrịa mamịrị acidosis nwere ike ịme ka ọrịa ahụ daa site na iji ọgwụgwọ na-ezighi ezi:
- Ufe insulin insulin.
- Akwụsịghị ọgwụgwọ.
- Obere insulin n’enweghi ike ịchịkwa glucose na ọbara.
- Ceptionmata ọtụtụ ihe ụtọ ma ọ bụ ntụ ọka, na-ahapụ nri.
- Insulin gbubiri ma ọ bụ chekwaa ọgwụ adịghị mma.
- Mkpịsị sirinji ma ọ bụ mgbapụta nwere nsogbu.
- Oge ndenye ọgwụ insulin maka ụdị ọrịa shuga mellitus nke abụọ ọ bụrụ gosipụtara
Na ọrịa na-efe efe, arụ ọrụ ịwa ahụ, ọkachasị na pancreas, mmerụ ahụ, oke ọkụ, yana n'oge ime, a chọrọ ịgbanwe insulin, ọ bụrụ na emeghị nke a, mgbe ahụ ihe egwu ketoacidotic coma na-abawanye.
Ketoacidosis nwere ike ime na iji glucocorticosteroids, diuretics, homonụ mmekọahụ, antipsychotics, immunosuppressants. Mmetụta ọnọdụ okpomọkụ na - emebi emebi n'ụdị frostbite ma ọ bụ ọrịa strok, ọbara ọgbụgba, nkụchi obi na ọrịa strok nwere ike ime ka mmụba nke ọbara na insulin ọzọ kwụọ ụgwọ.
Site n'ọrịa shuga dị ogologo ruo ogologo oge, mbelata insulin na-amalite, nke chọrọ ịgbanwe insulin.
Ketoacidosis nwere ike ịbụ ngosipụta mbụ nke ọrịa shuga 1.
Mgbaàmà na ọgwụgwọ nke ketoacidosis
Acidosis metụtara mkpo nke ahụ ketone na-etolite n’ike n’ike ọtụtụ ụbọchị, mgbe ụfọdụ enwere ike belata oge ihe a ruo awa iri na abụọ.
Na mbu, mgbaàmà metụtara mmụba nke glucose ọbara na-apụta: akpịrị ịkpọ nkụ, ọnya ụfụ ugboro ugboro, akpọnwụ akpọnwụ, adịghị ike, isi ọwụwa na nkụ, mbelata nri, ụra, na iku ume acetone. Ihe ndị a bụ akara nke ketoacidosis dị nro.
Site na mmepe nke arụ ọrụ ketone, a na-agbakwunye ọgbụgbọ na ọgbụgbọ, ọnya siri ike nke acetone na-apụta site n'ọnụ, iku ume na-eme mkpọtụ ma dị omimi. Ahụ ndị dị na Ketone bụ ihe na-egbu egbu na ụbụrụ, yabụ ndị ọrịa na-aghọ nkọ, iwe, isi ọwụwa, mgbagwoju anya, ụmụ akwụkwọ na-anabata ọkụ ma na -echekwa obi mkpụrụ obi ugboro ugboro.
Acids na-akpasu akpụkpọ ahụ nke mucous nke afọ na eriri afọ, yabụ enwere mgbu mgbu na erughị ala na mgbidi nke eriri afọ, nke yiri ihe mgbaàmà nke usoro mgbu ma ọ bụ ọnya afọ. N'otu oge ahụ, ọrụ mmegharị nke eriri afọ na-esighi ike.
Ọbara ọbara amalitela mbelata, ihe mmamịrị na-agbadata. Foto a dakọtara kwekọrọ na ịdị njọ nke ọrịa shuga ketoacidosis.
Site na mmụba nke ketoacidosis, ihe ịrịba ama nke precoma pụtara:
- Mmetụta okwu.
- Akpịrị ịkpọ nkụ: akpụkpọ akpọnwụ na akpụkpọ mucous; ọ bụrụ na a pịa ya na nku anya, ha dị nro.
- Mmejọ nke mgbanwe ụmụ akwụkwọ, ụmụ akwụkwọ na-aghọ warara.
- Eku ume iku ume.
- Imeju na-abawanye.
- Mmepo.
- Mgbakwunye anya mmegharị.
- Mbibi ntị ya n'ụdị ịla n'iyi, ihe ndọghachi azụ ma ọ bụ ọgba aghara.
Na akara izizi nke ketoacidosis, a na-egosi ụlọ ọgwụ ga - abịa ngwa ngwa. Iji kwado nchoputa a, a na-eme omumu ihe omumu glucose (o nwere ike karie ka 20 - 30 mmol / l), pH, na aru ketone di n’ime obara.
Ọzọkwa, a na-enyocha ọnụnọ nke ketones na mmamịrị na ọdịnaya nke bicarbonates n'ime ọbara, a na-ekpebikwa sodium na potassium n'ime ọbara, urea na creatinine. Iji ewepu lactic acidosis, a na-enyocha ọkwa lactic acid dị n'ọbara.
A na-ahụta Ketoacidosis na insulin, a na-enyochakwa glucose ọbara n'ọtụtụ awa ọ bụla; a na-egosikwa nchịkwa nke potassium na sodium bicarbonate na ntinye nke ụkọ mmiri nwere ọbara.
A na-agwọ ọrịa oria na-akpata acidosis.
Lactic acidosis n’ime ọrịa shuga
Nchịkọta nke lactic acid n'ime ọbara, karịa ọkwa 5 mmol / l, na-akpata mmụba na acidity ọbara. Ọnọdụ a na - ebilite ma ọ bụrụ na abawanyela lactate, yana imeju imeju na akụrụ na-ebelata.
A na-emepụta Lactic acid site na sel ọbara, akwara anụ ahụ, akwa ụbụrụ nke akụrụ, akpụkpọ ahụ mucous nke obere eriri afọ yana yana akwara. N'ime imeju, a na-agbanwe lactate ka ọ bụrụ glucose ma ọ bụ ejiri ya na usoro nke Krebs (ntụgharị nke citric acid).
Ọ dị lactic acid nwere ike ịbawanye elu site na ị consumptionụbiga ókè nke carbohydrates, nrụgide uche-mmetụta uche, ịxụbiga mmanya ókè, na-enwe nchekasị anụ ahụ ma ọ bụ nkwarụ.
Na ọrịa dị egwu nke obi na arịa ọbara, lactic acidosis siri ike na-amalite. Ọ nwere ike ịnwe ụdị ọrịa a:
- Ọrịa mgbu iku ume.
- Obi ịwa ahụ.
- Ọkpụkpụ okirikiri na angina pectoris, myocarditis, cardiomyopathy.
- Ọnwụ ọbara na akpịrị ịkpọ nkụ na mmepe nke coagulation intravascular
- Na sepsis.
- Oncological ọrịa.
Acidosis nwere mkpo nke lactate nwere ike bute nsị na methanol, calcium chloride, coma nke ebe ọ bụla si. Ọgwụ shuga dị n’etiti ìgwè ndị biguanide (Metformin 850 ma ọ bụ Fenformin) na-egbochi guzobe glucose n’imeju site na lactate, n’ihi ya, lactic acidosis nwere ike ịbụ nsogbu n’ihe gbasara ịgwọ ọrịa shuga.
Lactic acid na nnukwu ịta ahụ bụ ihe na-egbu egbu nye sistemụ akwara. Ya mere, na mmepe nke acidosis, nkụda mmụọ nke nsụhọ, ọdịda okuku ume na ọrụ nke sistem na-etolite etolite. Ihe mgbaàmà nke lactic acidosis mamịrị anaghị adị iche na ketoacidotic iche. Nanị ihe e ji mara ya bụ mbata ọbara ọgbụgba na mmepe nke ọnọdụ ụjọ.
Maka nyocha nke lactic acidosis, ndị na-egosi pH ọbara na-eduzi ha - mbelata ihe karịrị 7.3 mmol / L, ụkọ bicarbonate n'ime ọbara, mmụba nke ọkwa lactic acid.
A na-enye ọgwụgwọ Acidosis n'ọnọdụ ọnọdụ ịba ụba nke lactate site na nchịkwa buru ibu nke saline na sodium bicarbonate, ọgwụ lipoic acid na carnitine.
Mgbe ha na-ede insulin, ihe na-egosi glucose ọbara na-eduzi ha.
Ọ bụrụ na ọ dị elu karịa 13.9 mmol / l, mgbe ahụ ọbụlagodi na enweghị ketoacidosis, a na-egosi ndị ọrịa insulin na obere usoro.
Mgbochi Ọrịa Acidosis
Iji gbochie nsogbu shuga, a ga-ahụrịrị iwu ndị a:
- Nri oriri nwere ike igbochi mmụba nke ọbara - nri shuga na ngwaahịa ntụ ọka, na - agbaso usoro ọchịchị mmanya.
- Nri site na oge awa, na-eburu n'uche inje insulin.
- Usoro ọgwụgwọ insulin na-achịkwa glucose ọbara.
- Inggbanwe uzo ogwu ogwu di ire ya na oria oria, oria, oria, na ime.
- Oge na-agbanwe insulin na ụdị ọrịa shuga 2.
- Nnyocha mgbe niile nke endocrinologist na nyocha nke biochemical maka glycated hemoglobin, cholesterol na metabolism metabolism, gbasara akụrụ na hepatic.
- Chọọ nlekọta ahụike mberede na mgbaàmà mbụ ma ọ bụ acidosis chere.
Vidio dị n’isiokwu a ga-aga n’ihu n’okwu gbasara nsogbu ọria mamịrị.
