Elldị shuga abụọ nke ọrịa mellitus na-ewere ọnọdụ na nzaghachi nke ndị na-anabata anụ ahụ nye insulin ahụ mepụtara. Ihe na - akpata insulin iguzogide nwere ike ibu ihe a ketara eketa, ọ na - eme ka ọ bụrụ oke ibu, hypercholesterolemia, ọbara mgbali elu.
A na-eji ọgwụ agwọ ọrịa shuga 2dị nke 2, nke nwere ike ịmụba ikike insulin na, ya mere, na-ejigide ọkwa glucose ọbara nkịtị.
Ọgwụ a na-egosikarị maka ịgwọ ndị ọrịa shuga bụ Metformin, aha ahia Siofor, Glucofage, Dianormet. Mmasị n'ebe ọ nọ kemgbe ihe karịrị afọ 60 ojiji akwụsịbeghị, nchọpụta sayensị na-emepekwa ohere ndị ọhụrụ maka iji ya.
Njirimara Metformin
A na-ejikarị ọgwụ eji agwọ ọrịa shuga ọgwụ na mbadamba, yana ihe ngosi, enwere ike ịkọwa insulin tinyere ha. Ma, maka ọrịa ọhụụ achọpụtara, yana ọnụnọ nke ọrịa shuga shuga, karịsịa jikọtara ya na oke ibu, ndị dọkịta gburugburu ụwa na-edepụta Metformin.
Ọgwụ a na - egbochi irighiri glucose ọhụrụ n'ime imeju, nke na - enyere aka ịchịkwa glycemia n'èzí nri. Na-arịa ọrịa shuga, a na-amịpụta glucose ugboro atọ n'ime imeju karịa ka ọ dị na nke nkịtị. Site na ịgbalite usoro enzymatic, metformin na-ebelata glucose ọbara nke a tụrụ na afọ efu.
Mgbe ị theụsịrị ọgwụ ahụ na eriri afọ, a na - emebi ọgba aghara glucose ma mebie ya. Mmetụta ọghọm nke ọgwụ a na-apụtakarị mgbe ị na-eri nri nwere nnukwu carb ma na-egosipụta ya site na ịbawanye ụba na motility eriri afọ.
Na mgbakwunye, nsonaazụ nke Metoformin na usoro metabolic gosipụtara n'ụzọ a:
- Ọnụ ọgụgụ ndị na-anabata insulin na-anabata ọrụ insulin na-abawanye.
- Ọnụego mgbanye glucose n’ime sel na - abawanye.
- A na-eme ka oxidation nke ọdụdụ abawanye.
- A na-ebelata ọdịnaya nke abụba atherogenic.
- Ọbara insulin ọbara na-akwụsị.
- Ọ na - eme ka ọbara mara ihe dị mma.
Ngwongwo Metformin ndị a na-enye ohere iji ya maka ọgwụgwọ nke ọrịa shuga 2, ma dị ka ngwa nnwere onwe yana ya na mbadamba ndị ọzọ, ọgwụ na-ebelata shuga, insulin.
Ojiji nke Metformin na-enyere aka ọ bụghị naanị iwetata shuga ọbara nwa oge, kamakwa ọ na-egbochi nsogbu nke ịrịa ọrịa shuga na sistem.
Cribdebe Metformin maka Ọrịa Shuga
A na-ahọrọ dos nke Metformin n'otu n'otu, na-amalitekarị na 500 mg n'abalị. Mgbe ahụ jiri nwayọ, ị nwere ike iwelie 3 g kwa ụbọchị. Ọ bụrụ na ụdị ọgwụ dị otú a anaghị eweta nsonaazụ achọrọ, mgbe ahụ, ọ na-ehichapụ ma ọ bụ tinye ya na ọgwụ ndị ọzọ, gụnyere insulin.
Ọgwụ na-abụkarị na mmalite ọgwụgwọ na-akpata mgbaàmà nke nsogbu nke eriri afọ: flatulence, metallic, ọgbụgbọ na afọ ọsịsa. Mgbe imeghari ka usoro doses dị obere, ihe ịtụnanya ndị a na-apụ n'anya. Mgbe ịictionụbiga mmanya ahụ, gbakwunye 250 mg kwa ụbọchị kwa ụbọchị 3-5 ruo mgbe ọkwa glycemia na-atụ aro ruru.
Ọ bụrụ na edepụtara insulin n'otu oge, mgbe ahụ usoro Metformin dị mbụ bụ 500-850 mg ugboro abụọ n'ụbọchị. A na-ahapụ ụmụaka ka ha jiri Metformin mgbe afọ iri gachara. Enwere ike ịkwado ya maka nguzogide insulin nke abụọ n'oge ogba.
Contraindications:
- Ketoacidosis, coma na precoma.
- Pathology nke akụrụ ya nwere ikike ịmụba ike.
- Enweghi oke mkpocha mmiri.
- Okpo iku ume na nkụchi obi.
- Ọrịa imeju na-adịghị ala ala nwere oke ọrụ.
- Mmanya
Metformin na ingka nká
Ihe omumu banyere ihe omuma nke ogwu ahu mere ka atumatu ndi ozo ghara idi nma. N'ime nyocha banyere nsonaazụ ahụike nke oxidation n'efu, ndị sayensị kwubiri na a ga-agwọ ịka nká. Banyere Metformin Malysheva na vidiyo ahụ na-ekwu maka dị ka usoro nkwalite nke nnabata na mweghachi nke ọrụ furu efu.
Na afọ, ọrịa shuga na-abawanye, nke na-enye anyị ohere ịtụle ụdị shuga 2 dị ka ọrịa ịka nká, ma, ya mere, na-emeso ọ bụghị naanị imebi metabolism, kamakwa na-egbochi usoro mbibi sel.
Ọkpụkpụ glucose n’arụ ọbara na-emetụta mbibi nke eriri kompeni ma na - akpata mmụba ahịrị. Dika Malysheva Metformin, Glyukofazh, Siofor, Metamin kwuru, ha nwere ụdị omume ahụ, ebe ha nwere otu ihe arụ ọrụ.
Nsonaazụ ọgwụ n’arụ n’arụ
N'ime ihe ngosipụta maka iji ọgwụ dịka Glucofage ma ọ bụ Metfogamma, nke na-emepụta metformin mbụ, enweghị ihe ngosi nke iji ya dị ka ụzọ nnwere onwe maka ịbelata ibu, ebe enweghị ihe akaebe na-egosi na Metformin dị ogologo ndụ.
Mmụta dị otú ahụ na-aga n'ihu, a na-ejikwa ọgwụ nwere metformin eme ihe n'ụzọ gara nke ọma iji merie ihe mgbochi insulin na ndị ọrịa buru ibu. Oke ibu na-enye aka na mmepe nke ọrịa shuga nke 2 n'ụdị ọnọdụ nke ya, ketara.
Ọ bụrụgodi na ezigbo ọrịa shuga anaghị etolite, mgbe ahụ n'ọnọdụ ọ bụla, oke anụ ahụ adipose na-akpali iguzogide anụ ahụ na insulin, nke na-eme ka e guzobe ya na akwara. Hyperinsulinemia, n'aka nke ya, na-akpata iri nri ma na-egbochi usoro ifelata.
Glucophage na ọgwụ ndị ọzọ yiri ya nwere ike imepe nje a, na-ebelata mmepụta nke insulin ma gbochie itinye abụba. Na mgbakwunye, n'okpuru nduzi nke nkwadebe metformin, usoro ndị dị otú a na-eme ahụ:
- Mmepụta nke abụba sitere na anụ ahụ adipose na mwepụ nke ahụ ha na-eme ngwa ngwa.
- Agụụ na-ebelata.
- Ntughari umeji imeju nke imeju na - akwalite mkpochapu abụba na carbohydrates.
- Mgbe ejikọtara ya na mmega ahụ na nri, oke ibu na-efu.
Enweghị ike ịtụle Glucophage dị ka panacea maka oke ibu, dịka Malysheva kwuru, mana ebumnuche ya bụ oke ibu, nke a na-ejikọta ya na ụdị shuga 2 ma ọ bụ ọrịa shuga. Ebe ọ bụ na ebumnuche ọgwụ a abụghị iji wedata shuga, mana iji gbochie mmụba ya, enwere ike ịkọpụta shuga ọbara nkịtị na metformin na nkwadebe ya.
Iji belata ibu na ezigbo ọnụego (500 g - 1 n'arọ kwa izu), a ga-ejikọ Metformin na nri kwesịrị ekwesị. Site na nri, ọbụlagodi na enweghị ọrịa shuga, a ga-ewepụrịrị carbohydrates dị mfe: shuga na ntụ ọka ọcha. Nke a metụtara ngwaahịa niile, ọsụsọ na-atọ ụtọ, dịka ha nwere molasses, sirop mkpụrụ, maltodextrin.
A na-atụ aro ya, yana ị presụ ọgwụ edenye, ịhọrọ nri nwere obere glycemic index na insulin index. Ihe ngosi ndị a gosipụtara ọnụego mmụba nke glucose na insulin n'ime ọbara mgbe ị risịrị otu nri ma ọ bụ ngwaahịa nri.
Enwere ike ikpebi ụkpụrụ sitere na tebụl pụrụ iche.
Metformin maka ọrịa polycystic ovary syndrome
Polycystic ovary syndrome dị na ụmụ nwanyị sobelata afọ ojuju nke homonụ mmekọahụ nke ụmụ nwanyị na mmụba nke homonụ nwoke, nke na-eduga n'ọgba aghara na osụsịrị osụ nwanyị, ime ka oge ịhụ nsọ ya na isi ike ịmụ nwa.
Ihe ịrịba ama nke polycystic bụ oke ibu. A na-achọpụta ndị ọrịa dị otú a mgbe enwere nsogbu ndidi, ọgwụ insulin na-eguzogide ọgwụ, nke ga-eme ka oge na-aga na-akpali mmepe.
Achọpụtala nyocha nke ụlọ ọgwụ na nhọpụta nke Metformin maka ọgwụgwọ dị mgbagwoju anya nke ọrịa a na-eduga n'ịhazi usoro metabolic na homonụ, nke na-eme ka akụkụ omumu nke ahụ nwanyị dị mma. N'otu oge ahụ, mbelata nke ahu, cholesterol na lipoproteins nke ụdị atherogenic ahụ.
Maka ọgwụgwọ, ejiri Glucofage mee ihe na 1500 mg kwa ụbọchị megide mmalite nke nri na-enye nri na mmachi nke carbohydrates, karịsịa abụba anụmanụ nwere ọrịa. Ihe oriri riri nke nwere obere protein abụba na fiber osisi.
Treatmentdị ọgwụgwọ a butere mweghachi nke nsọ nsọ ihe dị ka ụmụ nwanyị 68%.
Nsonaazụ
Ọrịa na eriri afọ na-egosipụta mmetụta kachasị njọ nke metformin na ọgwụ ya site na afọ na eriri afọ. Ọrịa dị iche iche na-eche ndị ọrịa gbasara afọ ọsịsa, eriri afọ, afọ, ihe ụtọ n'ọnụ, na ọgbụgbọ. Mgbe ị na-eri nri nke carbohydrate dị ukwuu, a na-eme ka mmetụta ndị a kawanye mma.
Iji chekwaa onye ọrịa ahụ site na ọrịa eriri afọ, a na-atụ aro idobere obere opekempe n’ụbọchị ndị mbụ, jiri nwayọ na-abawanye ha na ọkwa akwadoro. Otutu mgbe, mgbe ubochi asaa nke asaa gasịrị, nsogbu nke ị consequencesụ ọgwụ na-enyefe nke ha.
Maka ndị agadi, na ebumnuche afọ ntachi, mmetụta laxative nke Metformin nwere mmetụta dị mma na ọdịmma. Site na nnukwu afọ ọsịsa na afọ mgbu, enwere ike ịkagbu ọgwụ ahụ.
Otu biguanide, nke gụnyere Metformin na Metformin Teva, bụ ihe mgbaàmà dị egwu mara mgbe ị takingụsịrị ọgwụ ahụ, nke a na-akpọ steeti lactic acid. Ihe mejupụtara lactic acid bụ n'ihi eziokwu a ọgwụ na-egbochi njikọ nke glucose na imeju, nke a na-eji lactate.
N'ihi ihe ize ndụ nke lactic acidosis, amachibidoro ọtụtụ biguanides. Ihe ọghọm nke ime ya dị elu n’etiti ndị nwere obere ọrụ mkpolata, nkụchi obi, ọrịa ọria yana yana ị ofụbiga mmanya oke.
Ihe nrịba ama nke ọbara lactate:
- Akwara mgbu.
- Ọria afọ na mgbu.
- Ogbugbu na vomiting.
- Adịghị ike, adynamia, lethargy.
- Mkpọtụ na ngwa ngwa iku ume.
- Coma nwere nnukwu lactic acidosis.
Edebere Metformin maka oriri nwere obere kalori, mmiri na-egbu oke, n'oge afọ ime na inye ụmụaka nri, yana n'oge arụ ọrụ anụ ahụ ma ọ bụ ọrụ dị ukwuu, n'ihi na ọnọdụ ndị a nwere ike ịkwalite ngosipụta nke lactic acidosis.
Long theụ ọgwụ ogologo oge na-akpata anaemia, ịda mba, nsogbu ụra, ihe ịrịba ama nke polyneuropathy. Ihe ngosi ndi a bu hypovitaminosis nke B12. Ya mere, a na-atụ aro ị vitaminụ vitamin 20-30 kwa ụbọchị, ọkachasị enweghị protein na anụmanụ n'ime nri, dịka ọmụmaatụ, ndị anaghị eri anụ, ndị anaghị eri anụ.
Na vidiyo dị n'isiokwu a, Elena Malysheva ya na ndị ọkachamara ga-ekwu maka mmetụta Metformin nwere n'ahụ.
