Metglib 400 bụ ọnụọgụ hypoglycemic dị ọhụrụ maka ịgwọ ndị ọrịa shuga okenye. Ọ naghị ebute hypoglycemia, anaghị emetụta zoro ezo nke insulin n'ime ahụ. Theakingụ ọgwụ na-enye nsonaazụ dị mma n'ịgwọ na ịchịkwa ọrịa shuga.
International Nonproprietary Aha
INN - Glibenclamide + Metformin.
ATX
Koodu dika nhazi nke ATX bu A10BD02.
Ha weputara udi ya na ihe mebere ya
Otu mbadamba 1 gụnyere 400 mg nke metformin hydrochloride na glibenclamide 2.5 mg. E tinyere mbadamba nkume ndị nwere ihe nkiri na-emetụta ya n'ime eriri afọ. Ihe ọzọ nwere calcium hydrogenphosphate dihydrate, sodium stearyl fumarate, povidone, microcrystalline cellulose.
Metglib 400 bụ ọnụọgụ hypoglycemic dị ọhụrụ maka ịgwọ ndị ọrịa shuga okenye.
Omume ọgwụ
Ngwá ọrụ nwere ngwakọta ọgwụ ọgwụ hypoglycemic nke otu ọgwụ ọgwụ dị iche iche - metformin, glibenclamide. N'ihe metụtara biguanides, Metformin na-ebelata oke glucose. O nwere usoro ndi a n’aru aru:
- mbelata nke ukwu nke imepụta glucose na akwara nke imeju;
- ịmụba uche nke ndị na - anabata ndị na - anabata insulin;
- mụbaa usoro oriri na nhazi nke glucose na sel akwara;
- nnabata nke glucose n’ime akwara nri;
- mmegide ma obu oke ibu na ndi oria shuga.
Metformin nwere mmetụta dị mma na nguzobe nke lipids ọbara. Na-ebelata ịta nke cholesterol zuru oke, bụ isi n'ihi lipoproteins dị ntakịrị. Lowers triglycerides.
Glibenclamide bụ ihe mepụtara site na klas nke abụọ nke sulfonylurea.
Site na iji ya, ọnụ ọgụgụ shuga ọbara na-agbada, n'ihi na ọ na-akpali usoro nke insulin synthesis site na mkpụrụ ndụ beta nke pancreas. Ihe a mejuputara uto okpomoku nke Metformin. Ya mere, mbelata nke glucose ọbara dị mma, na-egbochi mmepe nke ọrịa hyperglycemia ma gbochie mmepe nke ọnọdụ hyperglycemic nnukwu.
Metformin nwere mmetụta dị mma na nguzobe nke lipids ọbara.
Mlọ ọgwụ
Mgbe ejiri ya mee ihe, a na-etinye glibenclamide kpamkpam site na mgbaze. A na-ekpebi itinye uche ya kachasị elu mgbe awa anọ gachara. Ihe fọrọ nke nta ka ọ bụrụ ihe nchebe na protein dị na plasma. Ọ bụ metabolized ma kpoo ya na bile, feces.
Metformin anaghị ejikọ protein protein. N'ihe na-adịghị ike, ọ na-emebi emebi, kpụrụ ya na mmamịrị. Akụkụ nke ọgwụ na-apụta na ure.
Site na usoro gbasara akụrụ, ọnụọgụ nke metformin n'ọbara na-ebili ntakịrị, n'ihi na akụrụ enweghị oge igosipụta ya. Nri adighi emetuta nnweta ogwu site na otutu biguanides.
Ihe ngosi maka ojiji
A na-atụ aro ka eji ya mee ihe nchoputa nke ụdị ọrịa shuga na-abụghị insulin na-akpata, ma ọ bụrụhaala na usoro ọgwụgwọ nri na agụmakwụkwọ anụ ahụ adịghị arụ ọrụ ma ọ bụ mgbe ejiri ọgwụ nke sulfonylurea. Enwere ike inye ya ọgwụ iji dochie usoro ọgwụgwọ gara aga site na iji usoro Metformin na sulfonylurea, ma ọ bụrụhaala na ọrịa nchịkwa nke onye ọrịa na-achịkwa nke ọma na enweghị ọnọdụ nke nnukwu hyperglycemic ọnọdụ.
Ka akwadoro maka iji nyocha nke ọrịa shuga na-enweghị insulin.
Ihe ngbanwe
Ọgwụ nwere ụdị contraindications:
- Ọrịa shuga 1dị 1.
- Nnukwu mmetụta nke anụ ahụ iji metformin, glibenclamide na ihe ndị ọzọ metụtara sulfonylcarbamides.
- Ọnọdụ siri ike nke na-enyere aka na mgbanwe nke ọrụ akụrụ: akpịrị ịkpọ nkụ, ọrịa siri ike, ujo.
- Ketoacidosis, precoma na coma.
- Akpachapu anya na ihe ndi ozo na aru mejuputara Metglib.
- Ọdịda ntaramahụhụ na nsogbu nephrological ndị ọzọ na-eme ka mbelata mmebi nke creatinine dị n'okpuru 60 ml / min.
- Nlekọta intravening nke x-ray nke nwere ayodiin.
- Ọnọdụ tinyere ikuku oxygen na anụ ahụ: ụkọ nke obi, ngụgụ, nkụchi obi.
- Ọkpụkpụ imeju, gụnyere ọrịa ịba ọcha n'anya.
- Porphyria (nke mebiri usoro nke metabolism metabolism, sochirinụ afọ ojuju nke porphyrins ọbara, gosipụtara site na ụba nke anụ ahụ rue ìhè anyanwụ, yana nsogbu ụjọ ma ọ bụ nke uche).
- Na-ewere Miconazole.
- Wa ahụ, mmerụ ahụ na oke ọkụ.
- Ọnọdụ chọrọ ọgwụ insulin.
- Alcoholingụbiga mmanya ókè.
- Lactic acidosis (gụnyere akụkọ ihe mere eme).
- Nrube isi na nri kalori nwere mmachi nke kalori kwa ubochi nke erughi 1000 kcal.
- Ndidi na-erubeghị afọ 18.
Jiri nlezianya
Edere ọgwụ ahụ iji nlezianya na okwu ndị a:
- ahụ ọkụ;
- alisụrụma;
- ụkpa adrenal;
- ịrụ ọrụ nke ọma na -eme ihe ọgbụgba;
- mebiri emebi usoro ọrịa thyroid;
- afọ karịa afọ 70 (enwere ihe ize ndụ nke hypoglycemia).
Etu esi ewere Metglib 400?
Ntụziaka ahụ na-egosi na a na-ewere ọgwụ ọnụ. Enweghi ike ịta ata ahụ, rie ya, gwepịa ya n'ime ntụ ntụ ma ọ bụ kwụsị. A gha-elo ya kpamkpam were were mmiri zuru oke sachaa ya. Anabataghị ị ofụ ihe ọ otherụ purposesụ ndị ọzọ maka nzube ndị a n'ihi mgbanwe mgbanwe omume hypoglycemic nke Metglib.
Ntụziaka ahụ na-egosi na a na-ewere ọgwụ ọnụ, a gaghị edetu mbadamba ụta ahụ, ata ata, ma ọ bụ ghee ntụ ma ọ bụ mee ya na nkwusioru.
Na-arịa ọrịa shuga
Usoro nke ọgwụ maka ọrịa shuga na-ekpebi site na dọkịta, dabere n'ọnọdụ onye ọrịa, metabolism metabolism. Maka oge ịhọpụta ọgwụ, ihe ngosipụta glycemic nwere mmetụta siri ike.
Ọtụtụ mgbe, usoro mbụ bụ mbadamba 1 ma ọ bụ abụọ kwa ụbọchị. A ga-eburịrị ya na isi nri. N’ọdịnihu, usoro onunu ogwu nwere ike ibubawanye n’ike n’ike nke glucose.
Oke kacha bụ 6 mbadamba. N'okwu a, ha kewara ụzọ atọ.
Nsonaazụ metglib 400
Mmetụta ndị na-esote nwere ike ime n'oge ọgwụgwọ:
- Enwere mgbanwe na ihe mejupụtara ọbara na steeti nke sistem, gosipụtara na agranulocytosis, leukopenia na thrombocytopenia. Ọrịa ndị a dị ụkọ ma na - apụ n'anya mgbe ịhapụ ọgwụ. Ọrịa hemolytic, ụmị ọkpụkpụ (ụkọ akwara), pancytopenia (ụkọ nke ihe niile emepụtara na ọbara) nwere ike ịkarị akari.
- Oge ụfọdụ ujolactic ujo nwere ike itolite. Enwere mmeghachi omume nke ịdị nkọ dị nkọ sitere na n'ụkpụrụ nke sulfonylurea.
- N'akụkụ nke metabolism, hypoglycemia, porphyria, mbelata nke nnweta nke vitamin B12, yana ojiji nke ọgwụ ogologo ogologo oge nke Metformin. Enwere ihe ize ndụ nke anaemia megaloblastic.
- Nri a na-adighi mma n’oghere a na-ekwu okwu ga-ekwe omume. Na mmalite ọgwụgwọ, obere mkpụmkpụ nke akụkụ nke ọhụụ na-eme n'ihi mbelata glucose.
- Ọtụtụ mgbe enwere ike ịnwe ọgbụgbọ, afọ ọsịsa, vomiting, mgbu n'ime afọ na mbelata (mgbe ụfọdụ enweghị agụụ). Ihe ngosi ndi a na - eme na mmalite nke ọgwụgwọ ma gafee ngwa ngwa. Iji ọgwụ ahụ n'ọtụtụ usoro na iji nwayọọ nwayọọ na-abawanye na usoro ọgwụgwọ ga-ebelata ohere nke ịmalite ihe ịrịba ama ndị dị otú ahụ.
- N’oge na-adịghị anya, nsị imeju na ụba ọrụ enzymes imeju nwere ike ime. N'okwu a, ịkwesịrị ịkwụsị ị .ụ ya.
- Mmeghachi omume ihu mmiri na-apụtakarị - itching, ihe ngbu, urticaria. Allergic vasculitis, erythema, na dermatitis nwere ike ịmalite mgbe ụfọdụ. Enweela ọnọdụ nke ịba ụba nke anụ ahụ rue ìhè anyanwụ.
- Mgbe ụfọdụ enwere ike ịbawanye ụba nke urea na creatinine na ọbara.
- N’oge na-adịghị anya, akụkụ nke ọkwa sodium ọbara belatara emeela.
Mmetụta ikike ịchịkwa usoro
N'ihi ihe ize ndụ nke ibute ọrịa hypoglycemia na ọkwa mbụ nke ọgwụgwọ, ọ dị mkpa izere ọrụ metụtara ịkwọ ụgbọ na ịchịkwa igwe. Tinyere ihe ize ndụ nke hypoglycemia, ọgụgụ isi nwere ike imebi.
Ntụziaka pụrụ iche
Ekwesịrị ịme ọgwụgwọ naanị n'okpuru nlekọta nke ọkachamara. N'oge usoro ọgwụgwọ, a ga-elezi anya ndụmọdụ nke dọkịta niile: nri dị mma, ilele anya mgbe niile na-ebu glucose ọbara na-ebu ọnụ mgbe ọ gachara.
Amachibidoro ị -ụ ọgwụ mmelata nke shuga.
Jiri n'oge ime na lactation
N'oge mmegharị ahụ, a na-egbochi contrasiga ahụ kpam kpam. Onye ọrịa ga-agwa dọkịta na ya na-eme atụmatụ ime ma ọ bụ na ọ bịara. Ọ bụrụ na ịtụrụ ime mere ka ị na-a theụ ọgwụ, ekwesịrị iwepụrụ ọgwụ ahụ ozugbo. Mgbe akagbuola Metglib, a na-enye onye ọrịa ọgwụ insulin (iwebata insịulin insulin iji belata ịba ụba shuga).
Emejuputara ya nke oma ka inye ogwu nke Metglib n’oge ara. Nke a bụ n'ihi enweghị data gbasara ike nke ihe ndị dị n’ọrụ nke ọgwụ si abanye n’ime mmiri ara ara. Ọ bụrụ na ọ dị mkpa iji ọgwụ mee ihe n'oge a na-enye nwa ara, a na-enye onye ọrịa ọgwụ insulin insulin ma ọ bụ bufee nwata ahụ na usoro nri.
Mpempe akwụkwọ Metglib maka Childrenmụaka 400
Edeghị ya.
Jiri na agadi
Ndị okenye kwesịrị ilebara ahụ anya pụrụ iche. Enwere ihe ize ndụ nke hypoglycemia siri ike.
Ngwa maka ọrụ ezughi oke ọrụ
Na dysfunctions gbasara akụrụ, a ga-eji ọgwụ kpachara anya, n'ihi mmụba nke ọkwa ọbara nke ihe ndị nọ n'ọrụ. Na ọnụal aha anaghị arụ ọrụ.
Iji nsị akụrụ, a ga-eji ọgwụ kpachara anya.
Jiri maka ọrụ imeju na-arụ ọrụ
Enweghị ike ịkọ ya maka mmerụ imebi ọnụ.
Mfe nke Metglib 400
Mgbe ị anụbiga mmanya ókè, hypoglycemia na-amalite. A na-akwụsị ịdị ala hypoglycemia dị ala site na oriri nke Grafica ozugbo. Shouldkwesịrị ịgbanwe usoro ị theụ ọgwụ ahụ ma mezie nri ahụ.
Na nnukwu hypoglycemia, mfu nke mmụọ na-eme, paroxysm, nsogbu akwara ozi nke chọrọ nlekọta ahụike mberede. Ntinye ọnọdụ dị njọ chọrọ iwebata Dextrose ngwa ngwa n'ime ahụ.
A na-enyo enyo na ọrịa hyperglycemia bụ ihe ngosipụta maka mmadụ ịga ụlọ ọgwụ ozugbo. Iji zere nlọghachi, ọ dị mmadụ mkpa inye ya nri nwere carbohydrates na-adịghị agbari.
Na ọrịa imeju na ndị ọrịa mamịrị, ọnụọgụ nke glibenclamide doro anya na-abawanye. Ya mere, ndị ọrịa dị otú a kwesịrị iji nlezianya nyochaa usoro nke ọgwụ. Mgbe ị na-eji Metglib dị elu, usoro ọgwụgwọ adịghị arụ ọrụ.
Ebe Metformin dị na ihe mejupụtara, ojiji nke Metglib mgbe niile n'ọtụtụ buru ibu nwere ike ịkpasu lactic acidosis. Nke a bụ ọnọdụ dị ize ndụ chọrọ nlekọta ahụike mberede. Enwere ike wepu Lactate na metformin site na nyocha.
Enwere ike wepu Lactate na metformin site na nyocha.
Mmekọrịta na ọgwụ ndị ọzọ
N'oge ọgwụgwọ, a machibidoro ojiji nke phenylbutazone n'otu oge iwu. Ọ na-abawanye ọrụ hypoglycemic nke Metglib. Ọ ka mma iji ọgwụ mgbochi ndị ọzọ na - egbochi steroidal maka ọgwụgwọ nke mgbu na ọnya.
Ejila ihe ndi ozo na sulfonylurea ma oburu na onye oria ewerela Metglib. Ma ọ bụghị ya, hypoglycemia siri ike nwere ike ịmalite.
Ojiji Bosentan na-abawanye ohere nke ị ofụ ọgwụ ọgwụ na imeju. Enwere ike belata mmetụta nke glibenclamide.
Mmanya ndakọrịta
N'oge usoro ọgwụgwọ, mmeghachi omume disulfiram ga-ekwe omume (nke ahụ gosipụtara site na mmeghachi nke ethanol na Antabus). Ọgwụ a ekwekọghị na ethanol.
Mmanya na-egbu egbu nwere ike ime ka ohere ịmụba ọrịa hypoglycemia siri ike na hypoglycemic coma. Ya mere, site na iji ọgwụgwọ Metglib, amachibidoro tinctures nwere mmanya.
Analogs
Analogues nke ngwaọrụ bụ:
- Glibenfage;
- Glibomet;
- Ndị Glucovans;
- Gluconorm;
- Gluconorm Plus;
- Metglib Force.
Ahịa ọgwụ na-ahapụ okwu
Relelị site na ndenye ọgwụ.
Enwere m ike ịzụta na ndenye ọgwụ?
Pharmfọdụ ụlọ ahịa ọgwụ na-ahapụ ire nke Metglib n’enyeghị ọgwụ dọkịta. Ndị ọrịa na-azụta ọgwụ na-enweghị oge ọhụhụ ọkachamara pụrụ ịnọ n'ihe ize ndụ n'ihi na ha nwere ike ịmalite nnukwu hypoglycemia.
Ọnụ ego maka Metglib 400
Onu ogugu nke ichikota (mbadamba 40) bu ihe ruru 300 rubles.
Ọnọdụ nchekwa maka ọgwụ
Chekwaa n’ebe ahihia, nke ikuku hapuru nke oke anwu anwu. Ọnọdụ nchekwa ọgwụ a ga - echekwa + 25 Celsius.
Bọchị mmebi
Enwere ike ịchekwa ọgwụ ahụ ruo afọ 3 site na ụbọchị a rụpụtara.
Emeputa
Mepụtara na Canonfarm Production, Russia.
Nyocha banyere Metglib 400
Ndi dibia
Irina, 38 dị afọ, endocrinologist, Obninsk: "Ana m edepụta Metglib nye ndị ọrịa ụdị ọrịa shuga dị mma 2. N'ime izu ndị mbụ, ndị ọrịa na-ewere mbadamba 2 kwa ụbọchị, mgbe ahụ dose ahụ na-abawanye na mbadamba 3-4. unu akarila ha. "
Svetlana, 45 afọ, endocrinologist, Moscow: "Metglib bụ ihe dị mma maka ịchịkwa ọrịa shuga na igbochi hyperglycemia. Ndị ọrịa na-anabata nke ọma, a na-ahụkarị ọrịa hypoglycemia na mmetụta ndị ọzọ adịghị ahụkebe."
Ndị ọrịa
Ivan, gbara afọ 50, Petrozavodsk: "Ọgwụ ọgwụgwọ dị mma nke na-arịa ọrịa shuga nke na-adịghị akpata ọgbụgbọ, ahụike adịghị mma ma n'otu oge ahụ na-enye gị ohere idobe shuga ọbara nkịtị.
Olga, onye dị afọ 42, Vologda: "Mgbe m mechara Metglib, ahụike m kawanyere mma. Ndị ọzọ na-arịa hypoglycemic na-akpata akpịrị ọgbụgba ọgwụ na-enyere aka mee ka shuga nkịtị na-enweghị mmetụ obi ụtọ."
Polina, 39 afọ, Kirov: "Ọgwụ dị ọnụ ala ma dị irè na-eme nke ọma, na-ebelata ọkwa shuga. Mmetụta ahụ na-abịa ngwa ngwa karịa ọgwụ ndị ọzọ. Enweghị mmetụta ọ bụla mgbe ịmalite ọgwụgwọ."
