Mbadamba heinemox nwere ike iwepu mbufụt nke ọrụ anaerobic, acid na-eguzogide ọgwụ na nje na-efe efe. Iji zere mmeghachi omume na-adịghị mma, ekwenye na ọgwụ ị ga-ekwenye na dọkịta na-aga ya.
International Nonproprietary Aha
Moxifloxacin (moxifloxacin).
ATX
J01MA14.
A na-ere ọgwụ antiimicrobial n'ụdị mbadamba 400 mg nke moxifloxacin.
Ha weputara udi ya na ihe mebere ya
A na-ere ọgwụ antimicrobial n'ụdị mbadamba 400 mg nke moxifloxacin (akụrụngwa nọ n'ọrụ).
Ihe ndi ozo mejuputara:
- silsila mmiri dioxide na-egbu egbu;
- sodium croscarmellose;
- cellulose microcrystals;
- steeti magnesium;
- udara talcum ntụ ntụ;
- sodium lauryl sulfate;
- 3000 macrogol;
- soya lecithin;
- iron oxide;
- White Opadry 85G58977.
Omume ọgwụ
Ọgwụ ahụ nwere ọtụtụ fluoroquinolones ma nwee mmetụta nje. Na-arụ ọrụ megide ọtụtụ anaerobes, ihe na-adịghị ahụ anya, microorganisms na-eguzogide acid (gụnyere gram-negative gram-positives gram).
Ihe ndị na-eme ka ndabere bụrụ mbadamba ihe dị iche iche na - egbochi ihe enzyme DNA nke nje, na - egbochi mmepe ha na ike ịmụ nwa. Usoro ọgwụgwọ moxifloxacin bụ ịdabere na ntinye aka nke akwara na plasma ọbara.
N'etiti usoro usoro fluoroquinolone, edepụtara mmeghachi omume mgbochi. Ma ọtụtụ anaerobes na nje na-egbu gram nke nje fluoroquinolones na-enwe mmetụta dị ukwuu maka mmetụta moxifloxacin.
Ihe ndị na-eme ka ndabere bụrụ mbadamba ihe dị iche iche na - egbochi ihe enzyme DNA nke nje, na - egbochi mmepe ha na ike ịmụ nwa.
Mlọ ọgwụ
Moxifloxacin na-etinye obi gị dum na obere oge. A na-ede Cmax na nkeji 30-240. Bioavailability nke MS ruru 90%. A na-ahụ ọkwa dị elu nke ihe ahụ na akpụkpọ ahụ azụ, sinus na anụ ahụ nke akụkụ afọ. Edere ya na ya na fits na mmamiri. Ihe dị ka ọkara ndụ-bụ awa iri na abụọ.
Ihe ngosi maka ojiji
Ihe na-eso mbufụt na oria na-efe efe nke microorganisms kpasoro anya maka ọgwụ a:
- obodo ọnya na-efe efe nke obodo sitere na Streptococcus anginosus na Streptococcus milleri;
- nnukwu ogbo nke ụdị bronchitis na-adịghị ala ala;
- sinusitis (nnukwu), nke nje pathogenic kpasuru iwe;
- ọrịa na-efe efe intra-abdominal (gụnyere ọrịa polymicrobial);
- ọnya anụ ahụ na ọnya anụ ahụ dị nro;
- ọrịa ọrịa pelvic, gụnyere endometritis na salpingitis.
Ihe ngbanwe
Ejiri ọgwụ ahụ maka ihe ndị a:
- nfụkasị soy na / ma ọ bụ ahụekere;
- hypersensitivity na moxifloxacin;
- Mmebi anụ ahụ Tendon mgbe ọgwụgwọ quinolone gasịrị;
- ngwakọta na antihistamines ịgbatị oge QT (Terfenadine, Astemizole), na ọgwụ nje antibacterial (Halofantrine);
- ndị ọrịa nwere nnukwu nsogbu nke imeju na akụrụ;
- obere afọ.
Ejiri nlezianya nye onye na-ahụ maka ọgwụ mgbochi maka ọrịa nke sistemu akwara, tinyere nkwarụ, psychoses, mmeghachi omume proarrhythmic, yana yana ịba ọcha n'anya yana yana ọgwụ ndị na-ebelata ogo potassium na ahụ.
Otu esi ewere Heinemox
Ekwesịrị ị oụ mbadamba ọgwụ antimicrobial ka dum, jiri mmiri sachaa ya. Ọ dị mma ime nke a mgbe nri gasịrị.
Nkezi onunu ogwu:
- oyi baa (ụdị obodo enwetara): a na-a drugsụ ọgwụ n’ime ọgwụ nke 400 mg; usoro ọgwụgwọ na-ewe site na 1 ruo izu abụọ;
- ọla kọpa (ya na ọrịa ịba ụba): ọgwụ kwa ụbọchị - 400 mg; oge nnabata bu ụbọchị 5-10;
- sinusitis nke nje oria: a na-enye ọgwụ ọgwụ mg mg 400 kwa ụbọchị; oge ọgwụgwọ - izu 1;
- akpụkpọ anụ / subcutaneous na-efe efe: dose - 400 mg; oge nke ọgwụgwọ sitere na 1 ruo izu atọ;
- Ọrịa nje intra-abdominal: usoro onunu ogwu - 400 mg; oge ọgwụgwọ - site na ụbọchị ise ruo ụbọchị iri na anọ;
- ọnya ọnya (anaghị agbagha), bụ akụkụ akụkụ ahụ pelvic: ọnụego kwa ụbọchị - 400 mg; Ogologo oge nnabata bụ izu abụọ.
Ekwesịrị ị oụ mbadamba ọgwụ antimicrobial ka dum, jiri mmiri sachaa ya.
Na-arịa ọrịa shuga
Mgbe ị na-a medicationụ ọgwụ, ndị ọrịa mamịrị kwesịrị ịdị na-enyocha oke glucose n'ọbara.
Nsonaazụ Heinemox
Site na anụ ahụ na akwara
- myalgia;
- arthralgia;
- uda olu;
- ogwe akwara;
- adịghị ike
- ọrịa ogbu na nkwonkwo;
- iwe iwe nke myasthenia gravis;
- mbibi akwara.
Ọkpụkpụ afọ
- afọ mgbu;
- ọgbụgbọ
- afọ ọsịsa
- mẹ ivu;
- agụụ riri;
- stomatitis
- dysphagia;
- colitis (ụdị pseudomembranous);
- eriri afọ.
Ahụhụ Hematopoietic
- mụbara INR / ịgbatị oge PV;
- mgbanwe na mkpokọta thromboplastin;
- leukopenia;
- neutropenia;
- thrombocythemia;
- thrombocytopenia;
- anaemia
Sistemụ akwara Central
- Dizziness
- dysesthesia / paresthesia;
- nbibi nke uto;
- mgbagha;
- ehighi ura
- Obi erughị ala
- vertigo;
- ike ọgwụgwụ
- iro ụra
- ihe ịtụnanya;
- nsogbu ọrụ ọrụ okwu;
- hyperesthesia.
Site na usoro akwara obi
- ịgbatị nke oge QT na ndị mmadụ na-arịa hypokalemia;
- mmụba / ibelata ọbara mgbali elu;
- ventricular tachyarrhythmia;
- ụdị ọgwụgwọ arrhythmia na-enweghị nkọwa;
- obi dysfunctions.
Site n'akụkụ nke metabolism
- hyperuricemia
- mụbara ọkwa bilirubin;
- hyperglycemia;
- hyperlipidemia.
Ahụhụ
- eosinophilia;
- mmeghachi omume anaphylactic;
- ihe odide
- Ire Quincke;
- oji ibia laryngeal (ndu mmadu).
Ọrịa ntị na ọnya ọnya nwere ike ịpụta mgbe ụfọdụ.
N'oge ọgwụgwọ Heinemox, ngosipụta nke malfunction nke obi ga-ekwe omume.
Mmetụta ikike ịchịkwa usoro
Nke pụtara na ụdị fluoroquinolone nwere ike iduga mgbanwe na ọrụ psychomotor mgbe akpọrọ ha, yabụ n'oge a, ọ ka mma ịhapụ ịnya ụgbọ ala na ihe omume ndị ọzọ nwere ike ịdị ize ndụ.
Ntụziaka pụrụ iche
N'oge ị theụ ọgwụ ọjọọ, edere ọtụtụ ikpe nke ọnya anụ ahụ na-eyi egwu (ọrịa epidermal toc necrolysis, Stevens-Johnson syndrome). Ekwesịrị ịgwa ndị ọrịa tupu oge eruo na ọ bụrụ na mmeghachi omume ọ bụla emee, ị kwesịrị ịkpọtụrụ dọkịta ozugbo.
Achọghị iji ọgwụ ahụ agwọ ọrịa nke ọrịa nje bacteria na-eguzogide ọgwụ na-akpata.
Jiri n'oge ime na lactation
Ndi okacha machibidoro iji ogwu a n’oge di ime na mgbe di ime.
Ndị ọkachamara machibidoro ị ofụ ọgwụ a mgbe a na-enye nwa ara.
Jiri na agadi
N'ime ndị ọrịa dị otú a, a na-eme ka mmata uche banyere ọgwụ ahụ belata nke ukwuu, yabụ ekwesịrị ịhọrọ usoro onunu ogwu na-ewere ọnọdụ ahụike ha.
Inye umuaka
Edeghị ya ruo afọ 18.
Jiri maka ọrụ imeju na-arụ ọrụ
Ejiri nlezianya debe ya maka nsogbu ahụ.
Do Overụbiga Heinemox
N'okwu a, ọ dị mkpa ị attentiona ntị na foto ahụike. Therapy therapyụbiga ọgwụ ókè - na - akwado, dabere na nyocha site na iji ECG. Nchịkwa a na-ahụ maka carbon nke arụ ọrụ na-egbochi oke mmetụta nke moxifloxacin.
Nchịkwa a na-ahụ maka carbon nke arụ ọrụ na-egbochi oke mmetụta nke moxifloxacin.
Mmekọrịta na ọgwụ ndị ọzọ
N'iji ọgwụ antacids, multivitamins na mineral, na - emekọ ihe ọnụ, a na - agbadata mkpụchalata ma ọkwa plasma nke moxifloxacin na - agbada.
Site n'otu oge iji ọgwụ ọjọọ eme ihe na fluoroquinolones ndị ọzọ, enwere ihe ize ndụ nke ngosipụta fototoxic.
Ranitidine na-enyere aka belata nnabata nke moxifloxacin.
Mmanya ndakọrịta
Onye rụpụtara anaghị enye ozi gbasara ụdị njikọ a.
Analogs
- Avelox;
- Maxiflox;
- Vigamox;
- Moksimak;
- Moxigram;
- Aquamax;
- Alvelon MF;
- Ultramox;
- Simoflox;
- Rotomox;
- Plevilox;
- Moflaxia.
Ahịa ọgwụ na-ahapụ okwu
Ere ọgwụ
Ọnụahịa
300-380 nkp. kwa mkpọ Nke 10 (mbadamba 10, ihe mkpuchi nke ihe nkiri).
Ọnọdụ nchekwa maka ọgwụ
Ọgwụ a kwesịrị ịnọ n’ebe dịpụrụ adịpụ site na ụmụaka n’ebe ime ụlọ na-adịghị elu karịa + 25 Celsius.
Bọchị mmebi
Afọ 5
Emeputa
Highglans Laboratories HTP. LTD (India).
Nyocha
Olga Shapovalova, 39 afọ, Irkutsk
Ana m a theụ ọgwụ ahụ mgbe ọ bụla mgbe ọnyá afọ m na-akawanye njọ. Ọ na-eme nwayọ ma dịkwa ọnụ ala. Ejiri m ọgwụ ọzọ, mana site na nke a, enweghị m mmeghachi omume ojoo.
Victor Koklyushnikov, 45 afọ, Vladimir
Ejiri ya ọgwụ maka sinusitis, maka na ha na-egbochi ike ịchịkwa nje na-egbochi gram na-adịghị mma gram. Ọ gara rụ ọrụ n’ime izu 1.5 ka ebidochara ịgwọ ọrịa. Ndị na-ahụ maka ịwa ahụ wee laghachi na nkịtị, ọnọdụ ahụ kawanyere mma.