Neyrolipon bụ ọgwụ nwere ọgwụ antioxidant na mmetụta ịba ọcha n'anya mgbe ejiri ya. A na-eji ọgwụ ahụ eme ihe na ahụike maka ọgwụgwọ na mgbochi nke polyneuropathy nke mmanya mmanya ma ọ bụ ọrịa shuga na-akpasu iwe. Otutu ọnya nke ọgbụgba akwara na-anabatakwa ọgwụgwọ n'ihi ihe nke thioctic acid, nke nwere ezigbo uru na metabolism nke neurons.
International Nonproprietary Aha
Thioctic acid.
Neyrolipon bụ ọgwụ nwere ọgwụ antioxidant na mmetụta ịba ọcha n'anya mgbe ejiri ya.
Na Latin - Neurolipon.
ATX
A16AX01.
Ha weputara udi ya na ihe mebere ya
Ọgwụ dị n'ụdị usoro onunu ogwu 2: n'ụdị nke capsules yana dịka uche maka nkwadebe nke injections intravenous. Na anya, ihe kpuchie ekpuchi nke gelatin siri ike nke nwere odo odo di n’ime ya, ma n’ime ya nwere ihe oriri na-acha odo odo nke sitere na odo odo. Ngalaba nkwadebe nwere 300 mg nke ihe na - arụ ọrụ - thioctic acid. Dika ihe inyeaka n’ime ihe eji:
- hypromellose;
- steeti magnesium;
- silikoni dioxide dehydrogenated colloidal;
- mmiri ara ehi lactose;
- microcrystalline cellulose.
Ihe dị na mpụga bụ gelatin, titanium dioxide. A na-enweta agba agba nke ihe mkpuchi na-acha odo odo site na ọla edo.
Ọgwụ dị n'ụdị capsules.
Tinye uche
Onye anya ya na-anọchi anya ya site na mmiri mmiri na-ahụ anya etere na ampoules nke iko gbara ọchịchịrị nke nnukwu 10 ma ọ bụ 20 ml. Ọ dị mkpa iji ọgwụ ahụ kwadebe ihe ngwọta maka ntụtụ intravening. Dodị usoro onyonyo na-etinye 30 mg nke thioctic acid n'ụdị meglumine thioctate dị ka onyinye na-arụ ọrụ.
N'ime ihe enyemaka ndị a bụ:
- meglutin na nnwogha nke N-methylglucamine;
- macrogol (polyethylene glycol) 300;
- mmiri maka ịgba ọgwụ mgbochi 1 ml.
N’elu karama ndị ahụ, a na-egosipụta ebe ihe ezumike dị.
Dị adịghị adị
Ọgwụ ahụ adịghị n'ụdị mbadamba, rere naanị n'ụdị capsule. Nke a bụ n'ihi eziokwu ahụ bụ na mbadamba nkume enweghị ike ịnye ọnụego nnabata dị mkpa yana bioavailability zuru ezu iji nweta nsonaazụ ọgwụgwọ.
Omume ọgwụ
Ngwakọta ọrụ ọgwụ ahụ nwere mmetụta antioxidant na akụkụ cellular nke ahụ ma na-enyere aka sachapụ nsị nke toxins. N'otu oge ahụ, ihe akụrụngwa na-arụ ọrụ nke ọgwụ na-echebe mkpụrụ ndụ imeju pụọ na oke bekee nke kemịkalụ.
Akụkụ dị ike nke ọgwụ na-echebe mkpụrụ ndụ umeji buru oke ibu na nsonaazụ kemịkal nke kemịkalụ.
A na-etolite Thioctic acid n’ahụ n’ime obere obere, n’ihi achọrọ kọmpụta iji sonye na decarboxylation nke oxidative nke alfa-keto acid (na usoro nke Krebs). N'ihi ngwongwo coenzyme, thioctacid na-arụ ọrụ dị mkpa na metabolism ike nke mkpụrụ ndụ.
Ngwakọta kemịkal ahụ na-arụ ọrụ dị ka ọgwụ antioxidant na-egbu egbu nke na-emebi ma na-etolite ogige nwere radicals n'efu. Na-arụ ọrụ coenzyme na ngbanwe nke ihe na ogige na mmetụta antitoxic. Na mgbakwunye, alpha lipoic acid nwere ike iweghachi antioxidants ndị ọzọ, karịsịa megide mmalite nke ọrịa shuga mellitus. N'ime ndị ọrịa, mgbe ha na-a theụ ọgwụ ahụ, nguzogide insulin na-ebelata, n'ihi nke ogige kemịkalụ na-egbochi imebi usoro akwara dị elu.
Ọgwụ na -ebelata mkpụkọ plasma nke shuga n'ime ahụ ma gbochie ịmalite glycogen na hepatocytes. Tactic acid na - etinye aka na abụba na carbohydrate metabolism, na - ebelata cholesterol ma belata ohere nke atherosclerotic abụba na mgbidi nke arịa ọbara. Mgbe ị na-ewere Neyrolipona, enwere ọganihu na ọrụ imeju n'ihi mmetụta hepatoprotective.
Mmetụta ọgwụ ahụ bụ n'ihi nsonaazụ nke ọgwụ a na - arụ ọrụ na nsị nsị. Acid na-eme ka ihe ndị na-egbu egbu belata, ụdị oxygen na-emeghachi omume, nchịkọta nke ọla ndị dị arọ, nnu na ngwa ngwa mwepụ ahụ mgbe ọ na-etinye aka na metabolic cellular mitochondrial.
Mlọ ọgwụ
Mgbe ejiri ọnụ kwuo ya, a na-etinye 100 thicctic acid ngwa ngwa n'ime obere eriri afọ site na 100%. Site na iwebata nri n'otu oge, ọnụego mmịkọ ahụ na-ebelata. Bioavailability bụ 30-60% mgbe ntụgharị izizi gafere na sel akwara. Ọ bụrụ na ọ banye n’ọbara, ogige na-arụ ọrụ ruru ihe kachasị n’ime nkeji iri atọ.
Mgbe ejiri ọnụ kwuo ya, a na-etinye 100 thicctic acid ngwa ngwa n'ime obere eriri afọ site na 100%.
A na-agbanwe ọgwụ ahụ na hepatocytes site na nzaghachi conjugation na oxidative. Thioctic acid na ngwaahịa metabolic ya na-ahapụ ahụ ahụ n'ụdị mbụ ya site na 80-90%. Nkeji ọkara bụ nkeji iri abụọ na ise.
Ihe enyere n'iwu
A na-eji ọgwụ ahụ agwọ ọrịa ma gbochie polyneuropathy na-egbu egbu na neuropathy na-arịa ọrịa shuga.
Ihe ngbanwe
N'ọnọdụ ndị pụrụ iche, anaghị akwado ọgwụ ahụ ma ọ bụ machibidoro iji ya:
- ụmụaka na ndị ntorobịa erubeghị afọ 18;
- oge ito ime nwa na inye ara;
- ịba ụba nke anụ ahụ na ihe nhazi ọgwụ ahụ;
- intodị nkwekọrịta nke hectire na lactose, galactose, enweghị lactase na malabsorption nke monosaccharides na ahụ.
Jiri nlezianya
A na-atụ aro ịkpachara anya maka ọrịa shuga mellitus, ọnya ọnya afọ nke afọ na duodenum, hyperacid gastritis.
Uzo esi ewere NeroLipone
Mgbe ejiri ọnụ kwuo ya, n'ụdị capsules, a chọrọ ị drinkụ nkeji nke ọgwụ na-enweghị atụ. A na-etinye ọgwụ ahụ na afọ efu 30 nkeji tupu nri na a kwa ụbọchị nke 300-600 mg. Ọ bụ ọkachamara n'ọrịa na-ekpebi oge ọ ga-eji agwọ ọrịa. N'ọrịa siri ike, a na-atụ aro ka ịmalite ya site na iji ọgwụ eme ihe.
A na-eme nhazi intraven 600 kwa ụbọchị maka okenye. Ọ dị mkpa iji nwayọọ jikwaa infusion ya - ọ bụghị karịa 50 mg kwa nkeji. Iji kwadebe ihe eji eji mmiri eji atụ mmiri, ọ dị mkpa ịgwagbu 600 mg nke itinye uche na 50-250 ml nke 0.9% isotonic sodium chloride solution. Mmeghe a na-eme 1 oge kwa ụbọchị. N'ọnọdụ siri ike nke ọrịa ahụ, a na-eme ka usoro ahụ gaa ruo 1200 mg. Ekwesịrị ka echedoro ihe a kwadebere ka ọ ghara ikpughe anyanwụ na radieshon ultraviolet.
Ogologo oge ọgwụgwọ bụ izu 2-4, mgbe nke a gasịrị, ha na-atụgharị na ọgwụgwọ mmezi (na-ewere capsules) na usoro onunu ogwu nke 300-600 kwa ụbọchị maka ọnwa 1-3. Iji mee ka mmetụta ọgwụgwọ dị mma, a na-ahapụ ya imeghachi ugboro abụọ n'afọ.
Ọ bụ ọkachamara n'ọrịa na-ekpebi oge ọ ga-eji agwọ ọrịa.
Na-arịa ọrịa shuga
Na ọnụnọ nke ọrịa shuga, ọ dị mkpa ileba ọkwa shuga dị n’ahụ anya mgbe niile. N'ọnọdụ ndị pụrụ iche, ịkwesịrị ịgakwuru dọkịta gị banyere nhazi mmezi nke ndị na-ahụ maka hypoglycemic maka igbochi hypoglycemia.
Thioctic acid na-eduga na mgbanwe mgbanwe plasma nke pyruvic acid n'ime ọbara.
Mmetụta akụkụ neuroleipone
| Ahụhụ na sistemụ sitere na ihe mebiri sitere na ya | Nsonaazụ |
| Iri nri |
|
| Mmeghachi omume nfụkasị ahụ |
|
| Ndị ọzọ |
|
Dịka nsonaazụ n'akụkụ, rashes na-apụta.
Mmetụta ikike ịchịkwa usoro
Ọgwụ a anaghị emetụta ọrụ nke sistemụ akwara na akụkụ ụjọ. N'oge ọgwụgwọ ya na Neyrolipon, a na-anabata mkparịta ụka na usoro mgbagwoju anya, ịnya ụgbọ ala na ihe ndị ọzọ chọrọ ntinye na ọsọ nke mmeghachi omume.
Ntụziaka pụrụ iche
Ndị ọrịa na-enwekarị ngosipụta nke mmeghachi omume anaphylactic, tupu ịmalite ọgwụgwọ ọgwụ, a na-atụ aro ka ọ mee ule nke nfụkasị maka ịnagide ogige kemịkalụ owuwu.
Jiri na agadi
Ọgwụ ahụ enweghị mmetụta ọfụma na akụrụngwa akwara na akwara Central, mana n'ihi ohere nke mmeghachi omume na-adịghị mma maka ndị gafere afọ iri ise n'oge ọgwụgwọ ọgwụ, a na-adụ ọdụ ka ị na-eji ọgwụ ahụ. Achọghị ọgwụ ndị ọzọ kwa ụbọchị.
A na-adụ ndị gaferela afọ iri ise mgbe a na-agwọ ọgwụ ọgwụ ka ha kpachara anya mgbe ha na-a theụ ọgwụ.
Cribdebere Neurolypone ụmụaka
Amachibidoro ọgwụ a ruo mgbe ọ dị afọ 18, n'ihi na Onweghi data sitere na omumu omumu zuru oke banyere ikike nke kemịkal nke thioctic acid iji metụta uto mmadụ na mmepe na nwata na etolite etolite.
Jiri n'oge ime na lactation
Ihe dị na kemịkal nke Neyrolipona bụ nke contraindicated maka iji ya n'oge mmepe nke ẹmbrayo, dịka ogige nke ọgwụ na-enwe ike ịbanye na mgbochi placental ma na-akpaghasị ịtọlite akụkụ ahụ na sistem. Aakingụ ọgwụ bụ nke a na-eme naanị n'ọnọdụ dị oke mkpa, mgbe ihe egwu dị na ndụ nwanyị dị ime gafere ohere nke ọrịa intrauterine na nwa ebu n’afọ.
Edekwala oge HB.
Ngwa maka ọrụ ezughi oke ọrụ
A na-adụ ntị na ọnụnọ nke ọdịda akwara na-adịghị ala ala ma ọ bụ nnukwu akwara, dị ka 80-90% nke ọgwụ na-ahapụ ahụ n'ihi mmụba na ngwakọta nke tubular.
A na-adụ ntị na ọnụnọ nke ọdịda akwara ma ọ bụ nnukwu akwara.
Jiri maka ọrụ imeju na-arụ ọrụ
N'ime oke mmebi nke ọrụ mkpụrụ ndụ imeju, ọ dị mkpa ịdebe iwu kwa ụbọchị zuru oke ma na-elezi anya na nlekọta ahụike mgbe ị na-a theụ ọgwụ ahụ. Ọgwụ nwere mmetụta hepatoprotective, mana akụrụngwa nọ n'ọrụ mejupụtara ya na hepatocytes.
Site na mmerụ ahụ dị nfe na nke dị nro, a chọghị ndozi usoro usoro ọgwụgwọ ọzọ.
Doụbiga akwara ozi karịa
Abuse Withụ ọgwụ ọjọọ riri ahụ, ihe ịrịba ama nke ịdoụbiga mmanya ókè pụtara:
- ọgbụgbọ
- gagging;
- isi ọwụwa na ọgbụgbọ;
- ogwe akwara;
- ọgba aghara nke acid-base na mmiri-electrolyte nguzozi, nke jikọtara lactic acidosis;
- nnukwu nsogbu ọbara ọgbụgba na mmụba nke oge prothrombin;
- enwere ike mmepe nke hypoglycemic coma na ọnwụ.
Nausea bụ otu n'ime ihe ịrịba ama nke ịdoụbiga mmanya ókè.
Ọ bụrụ na onye ọrịa ahụ ewerela ọgwụ dị elu n'ime awa anọ gara aga, onye ahụ nwere nsogbu ga - eme ka ọ ọgbụgbọ, hichaa afọ ma nye ya ihe na-adọrọ adọrọ (unyi na-arụ ọrụ) iji gbochie mmịpụta nke Neuro lipon. Ọ bụrụ na enweghị otu ọgwụ mgbochi na - egbochi ọgwụgwọ, a na - achọ ọgwụgwọ iji kpochapụ foto overdose foto.
Ọkpụkpụ akụrụngwa na usoro akwara adị anaghị adị mma, maka ọgwụ ọgwụ ahụ adịghị egbochi protein ndị dị na plasma.
Mmekọrịta na ọgwụ ndị ọzọ
N'iji oge nke Neyrolipon na ọgwụ ndị ọzọ, ana-ahụta mmeghachi omume ndị a:
- Na-emegide nzụlite nke thioctic acid, ọ na-akwalite ọgwụgwọ ọgwụgwọ (mmetụta mgbochi mkpali) nke glucocorticosteroids.
- A na-ebelata ịdị irè nke Cisplatin.
- Ọgwụ Ethanol nwere ọgwụ na-ebelata ike ọgwụgwọ nke neuroleptone.
- Na insulin, a na-ahụ ọgwụ hypoglycemic maka nchịkwa ọnụ, a na-ahụta synergism (ọgwụ na-eme ka mmetụta ọgwụ nke ibe ha sie ike).
- Ngwakọta kemịkal Neyrolipona bụ ihe mejupụtara ya na ọla, yabụ ọgwụ adịghị atụ aro ka ewere ya na ndị nwere ọla (nkwadebe na ọnụnọ magnesium, iron, sọlfọ). Oge dị n'etiti ị medicationsụ ọgwụ kwesịrị ịdịkarịa ala elekere abụọ
Mmanya ndakọrịta
Amachibidoro ịveraụ mmanya na - aba n'anya n'oge a machibidoro ya na Neyroliponom amachibidoro. Mmanya Ethyl na-emebi mmetụta ọgwụgwọ nke ọgwụ ahụ ma na-akwalite nsị na mkpụrụ ndụ imeju.
Amachibidoro ịveraụ mmanya na - aba n'anya n'oge a machibidoro ya na Neyroliponom amachibidoro.
Analogs
Ọgwụ ndị a metụtara ihe ndochi maka usoro analogues nwere mmetụta ọgwụ ọgwụ yiri ya n'ahụ:
- Corilip;
- Berlition 300 na 600 nke Berlin-Chemie, Germany mepụtara;
- Corilip Neo;
- Lipoic acid;
- Lipothioxone;
- Oktolipen;
- Thiogamma;
- Thioctacid 600.
A naghị atụ aro ka ịme nnwere onwe gaa na ị anotherụ ọgwụ ọzọ. Tupu ị dochie ọgwụ ahụ, achọrọ ka gị na dọkịta gị nwee ndụmọdụ.
Ahịa ọgwụ na-ahapụ okwu
Ọ na-ere ọgwụ a site na ndenye ọgwụ.
Ọ na-ere ọgwụ a site na ndenye ọgwụ.
Enwere m ike ịzụta na ndenye ọgwụ
Ee e.
Ọnụ ego maka neuroleipone
Ọnụ ego nke capsules na Russia (iberibe 10 nke ọ bụla na paịlị dị mpekere 3, blisters atọ na igbe kaadi) bụ 250 rubles, maka karama ndị nwere ohere, site na 170 (kwa 10 ampoules 10 ruo 360 rubles). (kwa olu nke 20 ml).
Ọnọdụ nchekwa maka ọgwụ
Ọ na-atụ aro idobe ọgwụ ahụ n’ebe kpọrọ nkụ, na-ejedebeghị n’aka ụmụaka na ikpughe ọkụ anyanwụ, na okpomọkụ ruo + 25 Celsius.
Bọchị mmebi
5 afọ site na ụbọchị nke ahapụ. Amachibidoro ị toụ ọgwụ ahụ mgbe ụbọchị njiri gosipụtara na ngwugwu ahụ.
Emeputa
PJSC Farmak, Ukraine.
Nyocha banyere neuroleptone
Eugene Iskorostinsky, onye na-agwọ ọrịa, Rostov-on-Don
Echere m na okpu ndị ahụ ma lekwasị Neyrolipona nke nwere ezigbo mkpụrụ ndụ alpha-lipoic acid. Ana m a theụ ọgwụ ahụ mgbe niile na ọrụ m na-adakarị. M na-ahọpụta ndị ọrịa ka emeziwanye mmetụta nke akwara na ọnya akwara nke akwara ozi, karịsịa megide ọrịa shuga mellitus na dysfunction shuga. Ọ masịrị m na iji ọgwụ ọjọọ a mee ogologo oge ọ ga-ekwe omume, ma ọ nweghị mmeghachi omume ojoo.
Ekaterina Morozova, gbara afọ 25, Arkhangelsk
Ọgwụ ọgwụ megidere polyneuropathy na-arịa ọrịa shuga. Ejiri m capsule abụọ n'otu oge na ntinye aka na ntuziaka maka ojiji ahụike. Ọnọdụ ya bịara ka mma, shuga lara ọrịị. N'oge ọrịa ahụ, echefuru m ya (ọbụnadị mkpịsị aka ndị dị na mkpịsị aka), mana mgbe m theụrụ ọgwụ ahụ, mmata ahụ lọghachiri - ọbụghị ọsọ ọsọ, n’ime ọnwa abụọ. N'ime izu mbụ, achọrọ m ịkwụsị ọgwụgwọ n'ihi mmetụta na-adịghị ngwa, mana mgbe m nyochachara dọkịta ahụ, achọpụtara m na nke a bụ ihe dị mma. Enweghị mmeghachi ahụ nfụkasị ma ọ bụ mmeghachi omume ndị ọzọ na-emebi emebi n'oge ọgwụgwọ.
