Amaryl M - ihe iji belata glucose ọbara. Ọgwụ nwere ọrụ extrapancreatic, na-eme ka mkpụrụ ndụ insulin dịkwuo elu. Inye ndị ọrịa nwere ụdị ọrịa shuga 2 ụdị nri ya na ndụ ya.
International Nonproprietary Aha
Glimepiride + Metformin.
ATX
A10BD02.
Ha weputara udi ya na ihe mebere ya
Mwepụta weputara - mbadamba. Ihe ndị nọ n'ọrụ mejupụtara ya bụ gliperide na metformin na usoro nke 1 mg + 250 mg ma ọ bụ 2 mg + 500 mg.
Amaryl M - ihe iji belata glucose ọbara.
Omume ọgwụ
Ngwá ọrụ nwere mmetụta hypoglycemic. N'okpuru omume nke mmiri ndị na-arụ ọrụ, a na-ahapụ insulin site na mkpụrụ ndụ beta na-abanye n'ọbara. Ọkpụkpụ akwara na-eme ka insulin na-akpachapụ anya karị, a na-akwụsị usoro nhazi nke glucose site na ngwaahịa ndị na-enweghị carbohydrate, ọkwa LDL na triglycerides na-ebelata.
Mlọ ọgwụ
Ọmụmụ ọgwụ Pharmacokinetic na-akọ banyere mmachi nke glimepiride 100% na protein plasma. Site na ntinye n'otu oge, nnabata ya belata nwayọ nwayọ. Ọ dịghị mkpokọ akwara, a na-emeju ya n'ime imeju ya na imepụta metabolites abụọ, na-ewepu eriri afọ ya na mmamịrị (n'ụdị metabolites na-adịghị arụ ọrụ).
Metformin na-agbadata ngwa ngwa ma zuo ezu. Ọ bụghị biotransformed. N'ime ndị ọrịa nwere ọdịda akụrụ, ọ nwere ike ịgbakọ na anụ ahụ. Ọ na-apụta ya na mmamịrị.
Ihe ngosi maka ojiji
Edere ọgwụ ahụ maka ọrịa shuga 2, ọ bụrụ na enweghị ike idobe ọkwa glucose na ọkwa ahụ site na enyemaka nke nri na mmega ahụ.
Thedị ntọhapụ bụ mbadamba, ihe ndị na-arụ ọrụ n'ime ihe mejupụtara ahụ bụ gliperide na metformin na usoro nke 1 mg + 250 mg ma ọ bụ 2 mg + 500 mg.
Ihe ngbanwe
Ọnọdụ ọgwụ ọrịa na ụfọdụ ọrịa na-anabata nnabata nke ọgwụ a:
- ọdịda gbasara akụrụngwa na arụ ọrụ ndị ọzọ na-arụ ọrụ ha;
- ọnọdụ siri ike na arụ ọrụ imeju.
- mmanya na-egbu egbu;
- Ọnọdụ tupu coma ma ọ bụ coma;
- ụdị 1 ọrịa shuga mellitus;
- ihe nfụkasị na sulfonylureas, mmiri nke ọgwụ ma ọ bụ biguanides, sulfonamides;
- okpu iku ume;
- ọrịa ketoacidosis nke na-arịa ọrịa shuga, yana ọnọdụ ọjọọ na ala ala metabolic acidosis;
- nkụchi obi;
- infarction myocardial;
- lactic acidosis;
- ahụ ọkụ
- ọnụnọ nke ọrịa siri ike;
- nsị ọbara;
- eriri afọ akwara mkpọnwụ;
- nrụgide na ndabere nke mmerụ ahụ, ọkụ, arụmọrụ dị mgbagwoju anya, agụụ;
- mgbochi ụbụrụ;
- afọ ọsịsa
- na-egbu anụ ahụ na mmanya;
- imebi agbaji shuga mmiri ara ehi;
- afọ ruo afọ 18;
- galactosemia;
- lactation na ime.
Ekwesighi ịmalite usoro ọgwụgwọ n'oge ịba ọcha n'anya.
Jiri nlezianya
N'ọnọdụ ụfọdụ, iji mbadamba mbadamba mbadamba ụrọ:
- nri na-adịghị mma;
- enweghị mmega ahụ;
- nsị thyroid;
- ụkọ glucose-6-phosphate dehydrogenase;
- ọnụnọ ọrịa na-agbagha usoro nke ịrịa ọrịa shuga 2;
- ike nkịtị.
N’oge agadi, ịkwesịrị ị were ya n’okpuru nlekọta nke dọkịta.
Uzo esi ewere Amaryl M
Ekwesịrị iji nri mee ọgwụ nchịkwa ọnụ. Iwepu ogwu ekwesighi iduba ubara ogwu.
Na-arịa ọrịa shuga
Dọkita kpebiri ka dọkịta kpebie ya dabere na nchịkọta nke glucose dị n'ọbara. Were ọgwụ 1-2 ugboro n'ụbọchị. Oke kachasị bụ 4 mbadamba kwa ụbọchị.
Nsonaazụ Amarila M
A nabatara ọgwụ ahụ nke ọma, mana n'oge ụfọdụ, ọ nwere ike ibute nsonaazụ site na akụkụ na sistem dị iche iche.
Na ọrịa shuga mellitus, dọkịta kpebiri ka usoro ọgwụgwọ ahụ wee dabere na nchịkọta nke glucose n'ọbara.
Na akụkụ ahụ akụkụ nke ọhụụ
Ọdịda nhụ anya na-adawanye n'ihi nsụda dị n'ọbara glucose n'ọbara.
Ọkpụkpụ afọ
Ihe mgbaàmà sitere na ngwara nri: enweghị agụụ, nri tọgbọrọ chakoo, ọgbụgbọ, ọgbụgbọ, ihe mgbu na afọ, ịba ụba gas.
Ahụhụ Hematopoietic
Illsnweta ọgwụ nwere ike ibute mmepe nke pancytopenia (mbelata ihe ndị dị mkpa na ntinye ọbara), yana thrombocytopenia, aplastic anaemia na leukopenia.
Site n'akụkụ nke metabolism
Mgbaàmà nwere ike ime nke na-egosi mbelata mgbanye glucose ọbara: migraine, dizziness, sweating, ọbara mgbali elu, tachycardia, contractionary muscle contraction, jijiji, enweghị mmasị, iro ụra.
Ahụhụ
Enwere ọrịa urticaria, ihe ọkụ. N'ọnọdụ ndị a na-adịghị ahụkebe, ọnọdụ ahụ na-agbagwoju anya site na ujolactic jijiji.
Mmetụta ikike ịchịkwa usoro
Ọgwụ ahụ nwere ike iduga mmepe nke hypoglycemia, ya mere, a naghị atụ aro ka ị jikwaa usoro mgbagwoju anya n'oge usoro ọgwụgwọ.
Ntụziaka pụrụ iche
Site na ọdịda akụrụ na ọrịa imeju, lactic acid nwere ike ịgbakọ na ọbara na anụ ahụ (lactic acidosis). Site na mbelata nke okpomoku, aru nwa na mkpirisi iku ume, ikwesiri ịkwụsị igba ogwu. Nwa oge kwụsịtụrụ ịwa ahụ.
N'oge ọgwụgwọ, a na-atụ aro ka ị nyochaa oke nke glucose na ọbara iji gbochie mmepe nke hypoglycemia. Ọ dịkwa oke mkpa bụ nchịkwa nke ịta ahụ haemoglobin, creatinine na vitamin B12. Kwado glycemia site na mmega ahụ, nri.
Jiri na agadi
Ekwesịrị ilezi anya iji nyochaa ọrụ akụrụ.
Presdebere Amaril M ụmụaka
N'ime ụmụaka ndị gbara afọ 18, amachibidoro.
Jiri n'oge ime na lactation
Ọ contraindicated ịmalite ọgwụ n'oge ime na lactation. A ga-akwụsị ị Breastụ ara.
Ngwa maka ọrụ ezughi oke ọrụ
Na oke nrụrụ akụrụ na oke ọkwa kọmịnịstri edeghị.
Jiri maka ọrụ imeju na-arụ ọrụ
N'ime oke mmebi, akwara ọrụ imeju.
Nchọgharị nke Amaril M
Doụbiga ihe ókè na-eduga n'ịba ụba mmeghachi omume na mmepe nke hypoglycemia. Ọrịa shuga na-akwụsị ihe mgbaàmà hypoglycemia. A na-eme ọgwụgwọ Symptomatic.
Mmekọrịta na ọgwụ ndị ọzọ
Ọgwụ ahụ na ọgwụ ndị ọzọ na-emekọrịta.
- ojiji nke inducers ma ọ bụ ndị na-egbochi CYP2C9, tetracyclines, azapropazone, ndị na-ahụ maka antimicrobial nke quinolone, tritokvalin, MAO inhibitors na ACE inhibitors, fluconazole, coumarin anticoagulants, probenecid, anabolic steroidslafinfin, tritokvalina, beta-mgbochi, aminosalicylic acid na-eduga na mmepe nke hypoglycemia;
- ọ bụ ihe na-achọghị ka ikpokọta nchịkwa yana x-ray na iji ihe ayodiin nwere ayodiin;
- nifedipine na furosemide nwere mmụba nke Metformin n'ọbara;
- na-ewere antiamine H2 recepor blockers, clonidine na reserpine nwere ike ibute hyperglycemia ma ọ bụ hypoglycemia;
- ibuprofen anaghị emetụta ọgwụ ọgwụ;
- mbelata nke mmetụta hypoglycemic nwere ike ime n'okpuru mmetụta nke diuretics, epinephrine, nicotinic acid, acetazolamide, diazoxide, estrogens, rifampicin, barbiturates, sympathomimetics, corticosteroids, laxatives, phenytoin, homonụ thyroid.
Na mgbakwunye, ekwesịrị izere imekotaotu oge ịme ọgwụ na gentamicin.
Mmanya ndakọrịta
Ethanol nwere ike ịkwalite ma ọ bụ mebie mmetụta nke ọgwụ ahụ. N'ihi ihe ize ndụ nke hypoglycemia, acomụbiga mmanya ókè.
Analogs
N'ime ụlọ ahịa ọgwụ ị nwere ike ịzụta ọgwụ hypoglycemic ndị ọzọ na ihe mejupụtara:
- Ndị Glucovans.
- Glimecomb.
- Galvus Met.
Tupu ịmalite, ịkwesịrị ịgakwuru dọkịta iji gbochie ihe omume ọ bụla.
Ahịa ọgwụ na-ahapụ okwu
Relelị site na ndenye ọgwụ.
Enwere m ike ịzụta na ndenye ọgwụ
Inwere ike ịzụta ya mgbe inwetara ya ọgwụ n’aka dọkịta.
N'ime ụlọ ahịa ọgwụ ị nwere ike ịzụta ọgwụ hypoglycemic ndị ọzọ na ihe mejupụtara, dịka ọmụmaatụ, Glucovans.
Ọnụahịa Amaryl M
Ọnụ ego maka nkwakọ ngwaahịa sitere na 800 ruo 900 rubles.
Ọnọdụ nchekwa maka ọgwụ
Debe mbadamba nkume n'ime ebe gbara ọchịchịrị na okpomọkụ ruo + 25 Celsius.
Bọchị mmebi
Ndụ shelf bụ afọ 3.
Emeputa
Ndị na-ere ọgwụ Handok Co., Ltd., Korea.
Nyocha banyere Amarila M
Anna Kazantseva, onye na-ahụ maka ọgwụgwọ
Ofzọ ọgwụ a bụ imechi ọwa potassium ma mepee ụzọ calcium. N'otu oge ahụ, a na-ewepụta insulin na obere obere karịa n'okpuru ọrụ ndị ọzọ sitere na usoro sulfonylurea. Ya mere, enwere ihe ike nke ịmalite hypoglycemia belatara.
Anatoly Romanov, endocrinologist
Ihe mejupụtara ọgwụ ahụ na-agwakọta nke ọma. Ngwongwo hypoglycemic nke metformin na-egosipụta onwe ya n'oge ntọhapụ nke insulin na mkpụrụ ndụ beta. Metformin na - ebulite mmetụta nke glimepiride ma na - eduga n'ịbelata cholesterol "ọjọọ" n'ime ọbara na triglycerides. Ọ dị mkpa iji nlezianya drug ọgwụ ahụ ma ọ bụrụ na ọ nwere ọrịa gland na ọrịa imeju.
Eugene, 38 afọ
Ngwá ọrụ na-enyere aka ịchịkwa ọkwa glucose. Ana m ewere mbadamba 1 na afọ efu n'ụtụtụ ma enweghị m ike ichegbu ụbọchị niile. Aghọrọ m ọgwụ a na-ejikọ ọnụ dị ka dọkịta si kwuo. N'ihi nsonaazụ dị n'akụkụ, n'ihi mgbanwe nke glucose n'ọbara, ọhụụ jọrọ njọ, mgbe ụfọdụ ọgbụgbọ. Ka oge na-aga, mgbaàmà ahụ kwụsịrị. Enwere m afọ ojuju na nsonaazụ ahụ ma m ga-aga n'ihu ọgwụgwọ ahụ.