Gluconorm Plus na-ezo aka n'ụdị hypoglycemic multicomponent. N'ihi ọnụnọ nke ọtụtụ ihe eji arụ ọrụ, enwere ike inweta nsonaazụ dị mma n'oge ọgwụgwọ ngwa ngwa. Ngwá ọrụ a tụlere dị iche na analog nke otu aha (Gluconorm) na usoro onunu ogwu buru ibu. Ọzọkwa, ọgwụ abụọ ahụ na otu ụdị ụgwọ.
International Nonproprietary Aha
Metformin + Glibenclamide.
Gluconorm Plus na-ezo aka n'ụdị hypoglycemic multicomponent.
ATX
A10BD02.
Ha weputara udi ya na ihe mebere ya
Ọgwụ ahụ dị naanị n'ụdị mbadamba nkume. Nwere ihe ndị na-arụ ọrụ: glibenclamide na metformin hydrochloride. Usoro onunu ogwu na 1 mbadamba, n’otu n’otu: 2.5 na 5 mg; 500 mg Na mgbakwunye na ọgwụ ndị a, ihe mejupụtara ahụ nwekwara ụkpụrụ inyeaka maka ụdị ntọhapụ a:
- microcrystalline cellulose;
- hyprolosis;
- sodium croscarmellose;
- stereta magnesium.
A na-eji mbadamba nkume ndị nwere ihe pụrụ iche na-eme ka ọnụego ahapụta nke ihe ndị dị gara gara belata. N'ihi nke a, ọkwa nke ihe ike ike na mucous membranes nke afọ na-ebelata. You nwere ike ịzụta ngwaahịa a na ngwugwu nwere mbadamba iri atọ.
Ọgwụ ahụ dị naanị n'ụdị mbadamba nkume. Nwere ihe ndị na-arụ ọrụ: glibenclamide na metformin hydrochloride.
Omume ọgwụ
Usoro nke Gluconorm Plus sitere na njikọta nke ihe dị iche iche jikọtara ọnụ. Akụkụ nke ọ bụla na-arụ ọrụ na ụkpụrụ nke aka ya, mana n'otu oge ahụ na-eme ka mmetụta nke ọzọ dị. N'ihi mmetụta dị mgbagwoju anya, a na-ekpuchi usoro biochemical dị iche iche n'ime ahụ, nke na-eme ka mbelata glucose ngwa ngwa. Ya mere, metformin bụ nke biguanides. Nke a bụ ihe nnọchianya hypoglycemic nke na-arụ ọrụ dị iche iche n'otu oge:
- na-eme ka ọ̀tụ̀tụ̀ insulin dị na proinsulin ma jikọta insulin n'efu, ma Gluconorm a anaghị emegharị usoro a, mana ọ bụ nsonaazụ nke mmeghachi ahụ nke anụ ahụ nke ọgwụ a na-akpasu;
- na-ebelata mkpụkọ nke glucose n'ime ọbara, nke bụ n'ihi mgbochi nke njikọ nke metformin, n'otu oge ahụ ọ na - amalite usoro mgbanwe ya na sel.
Na-emegide ihe mmụba nke iwelata glucose, uche anụ ahụ na insulin na-abawanye. N'otu oge ahụ, mwepụta nke abụba n'efu na-akwụsịlata. Abụba na-egbu egbu dịkwa nwayọọ. Ọnụ ọgụgụ nke triglycerides, njupụta lipoproteins dị ala, na-ebelata. N'ihi nke a, a na -ebelata ọnụego nke ịmepụta ahụ, nke na-emetụta oke mmadụ. Na-emegide ihe oriri dị mma, nri nwere obere kalori yana mmega ahụ na-agafeghị oke, mmepe nke oke ibu na-akwụsị, nke kachasị mkpa maka ndị ọrịa mamịrị.
Mmetụta mmetụta ọgwụ ọjọọ na oke nke insulin dị iche iche bụ n'ihi mmeghachi omume ndị ọzọ. Yabụ, site na usoro ọgwụgwọ metformin, enweghị mmetụta ọ bụla na usoro nke mmepụta insulin, ebe ọ bụ na ihe a na-egosipụta akụrụngwa hypoglycemic, na-agbanye sel nke pancreas. N'agbanyeghi eziokwu na akwara a mebiri metabolism nke cholesterol, belata ntinye nke LDL, usoro ọgwụgwọ anaghị belata ọdịnaya nke HDL. N'ihi mmeghachi omume ndị a, ịdị arọ ahụ abụghị naanị ịkwụsị ịba ụba, mana a na-ahụta mbelata ya n'okpuru ọtụtụ ọnọdụ.
Ngwongwo ozo nke metformin bu ikike nke imeghari emechiri emechi. Yabụ, n'oge ọgwụgwọ Gluconorm Plus, akwara nke fibrinolytic dị n'ọbara. N'ihi nke a, a na-ebibi ọbara ọgbụgba ndị guzobere. Usoro a dị na igbochi plasminogen activates anụ ahụ.
Ngwongwo ozo nke metformin bu ikike nke imeghari emechiri emechi.
Akụkụ nke abụọ na-arụ ọrụ (glibenclamide) bụ otu nke usoro sitere na sulfonylurea. N'aka nke ụdị a bụ ihe kachasị dị irè nke ọgwụ hypoglycemic dị adị. Usoro nke ihe omume glibenclamide dabere na ikike nke ime ka mkpụrụ ndụ beta nke pancreatic. Mgbe gị na ndị na-anabata ha na-emekọ ihe, a na-emepe mmechi emepe potassium na ọ potassiumụ calcium.
Nsonaazụ nke mmeghachi omume ndị a bụ ịgbalite usoro mwepụta insulin. Ihe kpatara nke a bụ ka a na - abanye n ’akwara dị n’ime sel. Na ọkwa ikpeazụ, ewepụtara ike insulin n'ime ọbara, nke na-enye aka belata glucose. Nyere usoro nke ihe eji arụ ọrụ a, ọ bụ ihe amamihe dị na ya ka ọ jiri ya naanị na ọgwụgwọ ndị ọrịa nwere mkpụrụ ndụ beta nke pancreas. Ma ọ bụghị ya, ịdị irè nke glibenclamide belatara.
Mlọ ọgwụ
A na-etinye Metformin ngwa ngwa. Ọkwa nke uche ya na ọbara ọbara na-abawanye ruo uru ya ka elekere abụọ gachara. Mwepu nke ihe ahụ bụ obere ọrụ. Ka awa 6 gachara, mbelata plasma nke metformin bidoro, nke a bụ n'ihi njedebe ngwụcha usoro. Ndụ ọkara nke ihe ahụ belatara. Oge oge ya dịgasị site na awa 1.5 ruo ise.
Na mgbakwunye, metformin anaghị ejikọ protein protein. Ude a nwere ike imubanye n’anụ ahụ akụrụ, imeju, gland ndị nwere ume azụ. Ọrụ ezighi ezi na arụ ọrụ bụ isi ihe na-enye aka na nchịkọta nke metformin n'ime ahụ, nke na-eduga n'ịba ụba nke mkpokọta akụkụ a yana mmụba na arụmọrụ ya.
Ọrụ ezumike ezumike ezumike bụ isi ihe na-enye aka na nchịkọta nke metformin n'ime ahụ, na-eduga n'ịba ụba na arụmọrụ ya.
Glibenclamide dị ogologo oge - maka awa 8-12. Ọnụ ọgụgụ kachasị arụmọrụ pụtara na 1-2 awa. Ihe a na - egbochi ihe nchekwa ọbara. Usoro mgbanwe nke glibenclamide pụtara na imeju, ebe etolite kọlụm abụọ nke na-anaghị egosipụta ọrụ hypoglycemic.
Ihe ngosi maka ojiji
A nabatara ọgwụ a iji gwọọ ndị ọrịa nwere ọrịa shuga 2 n'ọrịa ụfọdụ:
- enweghị nsonaazụ ya na usoro ọgwụgwọ ebidoro iwu maka oke ibu, ma ọ bụrụ na eji ọgwụ ọ bụla eme ihe: Metformin ma ọ bụ Glibenclamide;
- na-eme ọgwụgwọ nnọchi, ma ọ bụrụhaala na ọkwa nke glucose n'ọbara bụ kwụsiri ike ma na-achịkwa nke ọma.
Ihe ngbanwe
Otutu amachi ebe ekwesighi iji ihe eji eme ihe
- anabataghị akụkụ ọ bụla na ihe mejupụtara (arụ ọrụ na arụ ọrụ);
- ụdị 1 ọrịa shuga mellitus;
- mebiri metabolism metabolism na ọrịa shuga;
- ọkwa mbụ nke mmiri;
- Coma;
- mbelata nke ukwuu na glucose ọbara;
- ọnọdụ ọnụnụ dị iche iche na-enye aka na nsogbu akụrụngwa na-arụ ọrụ, ọ nwere ike ịbụ nwayọ nwayọ n’usoro usoro mmiri, ọrịa, ujo;
- ọrịa ọ bụla esighi ike oxygen, n'etiti ha infarction myocardial bụ;
- lactic acidosis;
- ọtụtụ ọnụọgụ ọrịa nke bụ ihe ndabere maka ịhọpụta ọgwụ insulin, na nke a, mgbakwunye ọzọ nke ihe a nwere ike ibute mmepe nke nsogbu.
Etu esi ewere Gluconorm Plus?
Ogologo iwere mbadamba nkume na ọnụ ọgụgụ akụrụngwa arụ ọrụ ka ekpebiri iche n’otu n’otu. Ọnọdụ onye ọrịa nwere ọrịa mellitus, ọnụnọ nke ọrịa ndị ọzọ, na afọ na-emetụta nhọrọ nke usoro ọgwụgwọ. Ejiri nri a.
Na-arịa ọrịa shuga
Jiri ntakịrị usoro were were usoro ọgwụgwọ gwọọ ọrịa. Were 1 mbadamba kwa ụbọchị. Ọzọkwa, itinye uche nke ihe ndị nọ n'ọrụ nwere ike ịdị iche: 2.5 mg + 500 mg; 5 mg + 500 mg. Nke nta nke nta, ọnụọgụ nke metformin na glibenclamide na-abawanye, mana ọ dịghị karịa 5 mg na 500 mg, n'otu n'otu. A na-eme mgbanwe na ị ofụ ọgwụ ọjọọ kwa izu abụọ ruo mgbe ọnọdụ onye ọrịa ahụ kwụsiri ike.
Oke kacha ọgwụ kwa ụbọchị bụ mbadamba 4, ebe ọnụọgụ nke ihe ndị na-arụ ọrụ n'ime 1 pc: 5 mg na 500 mg. Nhọrọ ọzọ bụ mbadamba 6, mana ọnụọgụ nke glibenclamide na metformin bụ karị: 2.5 mg, 500 mg. E gosipụtara usoro ọgwụ ahụ gosipụtara n'ọtụtụ ọgwụ (2 ma ọ bụ 3), ọ dabere na ọnụ ọgụgụ mbadamba. Ewezuga bụ ikpe mgbe anaechekwa mbadamba 1 kwa ụbọchị.
Mmetụta Ọgwụ nke Gluconorm Plus
Enwere ihe ọghọm nke anya a na-ahụ anya n'ihi mbelata ọkwa glucose.
Ọkpụkpụ afọ
Vomiting, ya na ọgbụgbọ, oke agụụ, ọnya afọ, ụtọ nke ọla. A na - egosikarị ihe nrịbama nke ọrịa jaundice, ịba ọcha n'anya, ọrụ nke ịba ọcha n'anya na-abawanye. Nke a bụ nsonaazụ mgbanwe nke imeju.
Vomiting yana ọgbụgbọ bụ otu n'ime mmetụta ndị ọgwụ dị.
Ahụhụ Hematopoietic
Otutu ọgba aghara sochiri mgbanwe na ihe mejupụtara ọbara: thrombocytopenia, leukopenia, anaemia, wdg.
Sistemụ akwara Central
Ike ọgwụgwụ, isi ọwụwa na nkụchi, adịghị ike nke izugbe, uche na -akasị (adịkarịghị).
Carbohydrate metabolism
Hypoglycemia, akara nke ya bụ oke iwe, ọgba aghara, obi mgbawa, ọhụhụ, mkpọtụ, adịghị ike, wdg.
Site n'akụkụ nke metabolism
Lactic acidosis
Na anụahụ
Enwere akara nke hypersensitivity ka ìhè anyanwụ.
Ahụhụ
Urticaria. Ihe mgbaàmà bụ isi: ihe ọkụ ọkụ, itching, fever. Erythema etolite.
Ọgwụ nwere ike ịkpalite nfụkasị ụdị ụdị itching na ihe ọkụ ọkụ.
Mmetụta ikike ịchịkwa usoro
N'iburu n'uche na ọgwụ ahụ na-akpalite ọgba aghara nke anya, mgbe ụfọdụ na-enye aka na mmepe nke hypoglycemia, a na-atụ aro ka ị kpachara anya mgbe ọgwụgwọ ya na Gluconorm Plus mgbe ị na-anya ụgbọala.
Ntụziaka pụrụ iche
Edere ọgwụ a ka ọ kpachara anya ma ọ bụrụ na ọ na-emebi akwara thyroid, gia na-arịa ọrịa ahụ, na ahụ ọkụ yana enweghị ume.
N'oge ọgwụgwọ, a na-atụ aro ka ị nyochaa ọkwa nke glucose oge niile (na afọ efu na mgbe erichara nri).
Ọ dị mkpa ịgwa dọkịta banyere ịmalite ọrịa nke akụkụ ahụ mkpụrụ ndụ. Na nke a, enwere ike ịgbanwe mgbanwe na usoro ọgwụgwọ.
Na-emegide ihe gbasara ọrịa imeju na akụrụ, ịba ụba nke metformin n'ọbara na-abawanye, nke bụ nsonaazụ nke mbelata nke mkpochapu ihe a. N'ihi ya, lactic acidosis malitere.
Jiri n'oge ime na lactation
Edeghị ya.
Ebumnuche Gluconorm Plus maka ụmụaka
Ejighi ya, ọ bụ naanị ọgwụgwọ okenye ka a na-anabata.
Ejighị ọgwụ ahụ agwọ ụmụaka.
Jiri na agadi
A na-eji ọgwụ ahụ akpachara anya, karịsịa ma ọ bụrụ na onye ọrịa ahụ na-enwe mmega ahụ gabigara ókè. N'okwu a, ihe ize ndụ nke lactic acidosis na-abawanye.
Ngwa maka ọrụ ezughi oke ọrụ
Edekwala usọbọ maka ajọ mbibi nke anụ arụ a. Ihe njikwa nwebipụta ihe achọrọ. Site na mbelata dị ukwuu n'ọgwụgwọ.
Jiri maka ọrụ imeju na-arụ ọrụ
A na-egbochi ọgwụ ahụ iji bụrụ na ọ dara ọrịa imeju.
Nwepu nke Gluconorm Plus
Ngwá ọrụ a dị ize ndụ ma ọ bụrụ na ejiri ya mebie usoro ọgwụgwọ. N'okwu a, hypoglycemia na-etolite, ebe ọ bụ na usoro nke insulin ntọhapụ na-arụ ọrụ. N'otu oge ahụ, a na-egbochi glyconeogenesis na ojiji nke glucose karị. N'ihi nke a, na mmụba na ọnụọgụ nke Gluconorm Plus, nsogbu na-etolite.
Usoro ọgwụgwọ na-emetụta ịdị adị nke nri. Onye ọrịa ahụ ga-anwale ọgwụ carbohydrates n’ụdị ọ bụla. Ọ bụrụ na ajọ ọrịa bidoro, yana coma, a na-enye ọgwụgwọ n'ụlọ ọgwụ: a na-edozi ọgbụgba dextrose n'ime ọbara.
Mgbe dose nke Gluconorm Plus na-abawanye, lactic acidosis nwere ike ịmalite. Ọnọdụ ọrịa a chọrọ ọgwụgwọ n'ụlọ ọgwụ. Ọzọkwa, a na-ekpochapụ lactate na metformin site na anụ ahụ site na usoro ọgwụgwọ metụtara anụ ahụ. Iji wepu glibenclamide, usoro a adabaghị adaba, n'ihi na akụrụngwa a na protein dị n'ọbara.
A na-egbochi ọgwụ ahụ iji bụrụ na ọ dara ọrịa imeju.
Mmekọrịta na ọgwụ ndị ọzọ
Ojiji a na-ejigide Gluconorm Plus na Miconazole na-enye aka na mmepe nke hypoglycemia.
Achọghị ọgwụ ndị dị n’ime iodine na ọgwụ a nọ na ya. Ekwesiri iburu nke a n'uche mgbe ị na-eme nyocha nyocha chọrọ ojiji nke nkwalite iche na ihe nwere ayodiin.
Phenylbutazone na - eme ka ọgwụ a na - agbagha ike dịkwuo mma - ọ na - eme ka mbelata glucose dị egwu karị.
Besontan kpalitere mmụba nke nsị na nsị na imeju.
Ọtụtụ ọgwụ na ihe ndị chọrọ nlezianya:
- Chlorpromazine;
- GCS;
- beta-adrenergic agonists na ndị na-egbochi adrenergic;
- diureta;
- Danazole;
- Ihe mgbochi ACE.
Mmanya ndakọrịta
Ihe ọ beụ Alụ na-egbu egbu enweghị ike ikpokọta ya na Gluconorm Plus.
Analogs
Dochie ndị dị irè:
- Glibomet;
- Janumet;
- Metglib;
- Glucophage na ndị ọzọ.
Ahịa ọgwụ na-ahapụ okwu
Ogwu bu ogwu.
Enwere m ike ịzụta na ndenye ọgwụ?
Ee e.
Ọnụahịa Gluconorm Plus
Nkezi ego: 160-180 rubles.
Ọnọdụ nchekwa maka ọgwụ
Uzo okpomoku ka akwadoro: ruo + 25 ° С.
Bọchị mmebi
A na-echekwa ngwongwo nke ọgwụ ahụ afọ abụọ site na ụbọchị ahapụ.
Emeputa
Onye na-ere ọgwụ-Tomskkhimfarm OJSC, Russia.
Na nká, a na-eji ọgwụ elebara anya anya, ọ kachasị ma ọ bụrụ na onye ọrịa ahụ na-emega ahụ ọfụma.
Nyocha Gluconorm Plus
Ndi dibia
Valiev A.A., endocrinologist, 45 afọ, Vladivostok
Ngwọta dị irè. Enwere ike inweta nsonaazụ achọrọ nke usoro ọgwụgwọ fọrọ nke nta ka ọ bụrụ ozugbo, mana ihe ndị dị otú ahụ na-ejikọta ya na ihe egwu nke nsogbu. Mbelata ngwa ngwa glucose ọbara na-eduga hypoglycemia, yabụ ị nwere ike ị theụ ọgwụ ahụ naanị mgbe ịgachara dọkịta.
Shuvalov E. G., onye na-ahụ maka ọgwụgwọ, 39 afọ, Pskov
Ngwọta a na-arụ ọrụ zuru oke. Naanị enwere ike iwere ya na ụdị ọrịa shuga 2. Achọpụtara m ọnụ ọgụgụ dị ukwuu nke nsonaazụ, contraindications. Ana m elele uru dị ka ọnụahịa dị ọnụ ala, nke dị mkpa, n'ihi na ndị ọrịa na-agakarị ị theseụ ọgwụ ndị a.
Ndị ọrịa
Veronika, 28 afọ, Yaroslavl
Achọpụtara m ọrịa shuga n'oge na-adịbeghị anya. Mgbe m na-ebi ka mụ na ya biri, m chọrọ nri na oge ịchọrọ glucose. Ewerekwa ọgwụ a, ọ na - enyere aka ọsọ ọsọ, yana nke a bụ mgbakwunye, n'ihi na ụjọ kachasị m bụ coma megide ndabere nke mbelata ọkwa glucose.
Anna, 44, Samara
Ogwu adabaghị. Ọ na-akpali mmetụta ọjọọ. Isi ọwụwa, ọgbụgbọ, nkwarụ anya - ahụrụ m mgbaàmà ndị a niile. Dọkịta na mbụ kwenyere na okwu a dị ka usoro onunu ogwu, mana ọbụlagodi usoro ọgwụgwọ kachasị nro emeghị nsogbu ahụ.
