Iji chọpụta nke ka mma: Phasostabil ma ọ bụ Cardiomagnyl, ịkwesịrị iji ọgwụ ndị a tụnyere njirimara isi. Yabụ, na mbụ ihe contraindications, na-egosi, mmetụta, na usoro nke ọgwụ na otu nke ha Njirimara na-amụ. Mgbe ị na-ahọrọ, usoro onodu nke ihe eji arụ ọrụ na ụdị ntọhapụ na-arụ ọrụ.
Ihe e ji mara Phasostabil
Ihe na-arụ ọrụ bụ acetylsalicylic acid (ASA) na magnesium hydroxide. Ọgwụ dị n'ụdị mbadamba nkume. Ọ bụ nke otu ndị na - eme ka ihe ndị na - egbu egbu. Otu mbadamba 1 nwere 75 mg nke ASA na 15.2 mg nke magnesium hydroxide. Ihe mejuputara tinye ihe ndi ozo na adighi egosiputa ihe oru anacho:
- microcrystalline cellulose;
- sodium croscarmellose;
- povidone-K25;
- stereta magnesium.
Iji chọpụta nke ka mma: Phasostabil ma ọ bụ Cardiomagnyl, ịkwesịrị iji ọgwụ ndị a tụnyere njirimara isi.
Mpekere ndị ahụ bụ ihe mkpuchi nke ọgwụ, nke na-enyere aka belata ntọhapụ nke ASA ma chebe akpụkpọ ahụ nke afọ, yana duodenum na mmetụta ọjọọ nke ọgwụ. Acetylsalicylic acid bụ salicylic ester nke acetic acid. Ihe a sitere na NSAIDs (ọgwụ mgbochi mkpali na - abụghị steroidal). Ejiri mmetụta ejikọtara ya: ASA gosipụtara onwe ya dị ka ihe nyocha, wepụsịa akara nke mbufụt, na-ahụkwa maka ahụ ọkụ.
Ofkpụrụ nke usoro nke akụkụ a sitere na mgbochi nke ọrụ nke COX isoenzymes metụtara na mmepụta nke prostaglandin sitere na arachidonic acid na thromboxane. N'ihi ya, ike nke mmetụta ọjọọ ha na ahụ na-ebelata. Yabụ, prostaglandins na-etinye uchu na mmepe nke usoro mkpali. Ha na-emetụta usoro nke ịbawanye nnabata nke ndị na-anabata ya, si otú a na-enye aka na mmụba nke ihe mgbu.
N'okpuru mmetụta nke prostaglandins, nguzogide nke ogige hypothalamic na-ahụ maka thermoregulation na mmetụta na-adịghị mma nke ụmụ irighiri ihe na-ebelata. ASA na-egbochi usoro niile akọwara, n'ihi nke mbelata nke oke ume, mgbu na mbelata nke ahụ ọkụ ozugbo.
Ihe na-arụ ọrụ bụ acetylsalicylic acid (ASA) na magnesium hydroxide.
Na mgbakwunye, akụkụ a metụtakwara usoro nchịkọta platelet. Nke a bụ n'ihi n'eziokwu na ASA na-egbochi ọrụ nke endogenous thromboxane proaggregant. ASA bụ ihe dị mma maka antiplatelet sitere n'ọtụtụ analogues, n'ihi na ọ na-emetụta ọrụ nke thromboxane ozugbo.
Ma, acetylsalicylic acid na-enye mmetụ mgbochi dị nro. Nke a bụ n'ihi eziokwu ahụ bụ na ihe a na-egbochi COX-1 ruo nnukwu oke. Isoenzymes nke otu a na - etinye aka na usoro dị iche iche: na - emetụta akpụkpọ ahụ nke ngba nri, usoro ọbara gbasara akwara.
Acetylsalicylic acid dị obere na-emetụta enzymes cyclooxygenase COX-2, nke pụtara na ọ dị ala karịa ọtụtụ analogs na arụmọrụ nke mgbochi ọgụ, mmetụta analgesic. Na mgbakwunye, n'oge ọgwụgwọ na ọgwụ nwere ọgwụ a, a na-ahụkarị ọnụọgụ mmetụta dị n'akụkụ.
Phazostabil nwere akụkụ ọzọ na - arụ ọrụ - magnesium hydroxide. Ihe a sitere na otu nke antacids. Ejiri ezigbo mmetụta na ahụ. Yabụ, mgbe ị na-ewere acetylsalicylic acid na magnesium hydroxide, a na-ewepụta kọlọ magnesium chloride, n'ihi nke a na - emebi mmetụta hydrochloric acid guzobere n'oge metabolism nke ASA na - egbochi.
Mgbe magnesium chloride batara na eriri afọ, ọ na-egosipụta onwe ya dị ka ihe na-egbu egbu.
Na mgbakwunye, mgbe magnesium chloride na-abanye na eriri afọ, ọ na-egosipụta onwe ya dị ka ihe mgbu. Nke a bụ n'ihi n'eziokwu na ngwaahịa a anaghị anabata. Ọzọkwa, a na-achọpụta mmụba nke nrụgide osmotic na eriri afọ. Ọzọkwa, kloride guzobere n'oge mgbanwe nke magnesium hydroxide magnesium chloride na-eme ka peristalsis rụọ ọrụ. Nke a bụ n'ihi mmụba nke eriri afọ na mgbali mgbali na mgbidi ya.
N'ihi magnesium hydroxide, ọgwụ ASA adịghị enye aka na nsonaazụ ndị ọzọ. N'ọnọdụ ndị dị oke njọ, n'oge ọgwụgwọ, a na-ekwenye mmeghachi omume na-adịghị mma karịa n'ọnọdụ ọ bụla mgbe ejiri aspirin dị ọcha.
Pharmacokinetics nke Phasostabil
Ọgwụ a na-ajụ gbanwere maka obere oge. Ọzọkwa, metabolization na - apụta n'usoro nnabata.
Acetylsalicylic acid ka gbanwere ruo n’ime oke n’ime imeju, ebe ewepụtara metabolites, nke na-ekesa n’ime anụ ahụ na akwara niile. Mgbe minit 20, a na-enweta ọkwa kachasị elu nke itinye uche na ASA. Ikike kegide protin plasma na-adabere n ’ọgwụ ọ ofụ.
N'ime usoro wepụ acetylsalicylic acid, akụrụ so na ya. Nke a pụtara na ewepụtarịrị ihe ndị dị na mmamịrị ahụ. N’ime nkwarụ akwara, a gwọpụ ọgwụ ahụ kpamkpam ka ụbọchị 1-3 gachara. Ọ bụrụ na ọrịa nke akụkụ a etolite, ASA ji nwayọọ nwayọọ na-agbakọta na mgbasa ozi ndu (mmiri na akwara). Ihe na - ebute ịba ụba nke ihe a bụ mmepe nke nsogbu, ebe ọ bụ na metabolites nke acetylsalicylic acid nwere mmetụta dị egwu n'ahụ.
N'ime usoro wepụ acetylsalicylic acid, akụrụ so na ya.
Ihe na-egosi na contraindications, mmetụta dị n'akụkụ
Edebere Phasostabil n'ụdị ndị a:
- mgbochi nke mmepe nke pathologies nke akwara obi, karịchaa, nkụda obi, thrombosis n’iru ihe ndị dị ize ndụ, n’ime ha bụ ọrịa shuga, hyperlipidemia, ọbara mgbali elu;
- mgbochi nke ihe ịrịba ama nke infarction ugboro ugboro;
- obi mgbu;
- mbelata nke ukwuu na venous lumen mgbe akwara vaskụla.
Ọgwụ a na-ajụ n'ọtụtụ ọnọdụ:
- anabataghị ihe ndị na-arụ ọrụ nke phasostabil ma ọ bụ ọgwụ mgbochi mkpali na - abụghị steroidal;
- ọbara ọgbụgba;
- ụkọ vitamin K, nke bụ isi ihe na - eso akpata ntoputa nke ọbara ọgbụgba;
- ọrịa obi na-adịghị ala ala;
- ọgụ nke ikọ-ọria;
- nchikota nke otutu onwa na - enye aka na akuku iku ume: anwara asusu, polyposis imu, anagide acetylsalicylic acid;
- nnukwu oge mmepe nke afọ ọnya afọ;
- eriri afọ;
- iji ihe na-eme ka a na-ejikọta phasostabil na methotrexate;
- enweghi glucose-6-phosphate dehydrogenase;
- nnukwu ọrụ akụrụ na arụ ọrụ hepatic;
- lactation na ime ime (M na III trimesters);
- ụmụaka na-erubeghị afọ 18.
Phasostabil nwere ọtụtụ mmetụta ndị ọ na-enwe, bụ nke ihe mgbaàmà ndị a na-egosipụta:
- mbuze nke mucous nke afọ na eriri afọ;
- mgbu n'ime afọ;
- ọgbụgbọ
- gagging;
- obi mgbawa;
- perforation nke mgbidi nke digestive tract;
- mbufụt na nsonye na ọnya ọnya afọ;
- ọla;
- mbelata n'ọkwa hemoglobin na anaemia;
- mgbanwe ngbanwe na akụrụngwa nke ọbara na-eso ọnọdụ dịka thrombocytopenia, leukopenia, wdg;
- ọbara ọgbụgba
- nsogbu ụra;
- ọbara ọgbụgba;
- ntị anụrị.
Njirimara Cardiomagnyl
Nwere ike ịzụta ngwa a n'ụdị mbadamba. Ihe mejupụtara ya nwere otu ihe eji arụ ọrụ arụ ọrụ dịka nke anyị tụleburu na mbụ: acetylsalicylic acid, magnesium hydroxide. Agbanyeghị, a gosipụtara ọgwụ ahụ n'ụdị dị iche iche na usoro dị iche iche nke ihe ndị dị ike. Otu mbadamba 1 nwere: 75 ma ọ bụ 150 mg nke ASA; 15.2 ma ọ bụ 30.39 mg nke magnesium hydroxide. N'ihi ya, Cardiomagnyl bu ihe eji eme ihe dika Phasostubil.
Enwere ike ịzụta Cardiomagnyl n'ụdị mbadamba. Ihe mejupụtara ahụ gụnyere ihe ndị dị ike dị ka acetylsalicylic acid, magnesium hydroxide.
Ntụnyere Ọgwụ
Mmekorita
Isi ihe na ikpokọta ego a na-enyocha bụ otu ihe mejupụtara. Ojiji otu ihe eji eme ihe na emeputa n’eme ka i nweta ego nke na-aru oru n’otu iwu. N'ihi nke a, Cardiomagnyl na Phasostabil na-akpalite mmeghachi omume na-adịghị mma. Ugwu ndị dị na nhọpụta ọgwụ ndị a dịkwa otu. Jiri ọgwụ ndị ahụ echere na ọgwụgwọ nke ọrịa pathologies nke ụdị yiri ya.
Kedu ihe dị iche?
Cardiomagnyl bu ihe abuo n’etiti ndi iche. Otu n'ime nhọrọ bụ analogue nke Phazostabil (yana obere ọgwụ ASA na magnesium hydroxide). Yabụ, mgbe ị na-edepụta Cardiomagnyl nwere ihe ndị na-arụ ọrụ n'ime ego nke 150 na 30.39 mg (na mbadamba 1), mmadụ ga-atụkwasị obi na mmelite ahụ. Mmetụta dị mma na-enweta ngwa ngwa. Agbanyeghị, nsonaazụ ndị ọzọ na –eme nke ọma. Nke a putara na ihe ọghọm nke nsogbu na-abawanye, ọkachasị site na nri diges.
Kedu nke dị ọnụ ala?
Phasostabil bụ ọgwụ kachasị ọnụ ala. Enwere ike ịzụta ya maka 130 rubles. (mkpọ nwere otu mbadamba 100). Cardiomagnyl nwere otu usoro onunu ogwu (75 mg na 15.2 mg) riri 130 rubles, ma na nke a, egosiri maka ngwugwu nwere mbadamba iri ato.
Cardiomagnyl bu ihe abuo n’etiti ndi iche.
Kedu nke ka mma: Phasostabil ma ọ bụ Cardiomagnyl?
Ọ bụrụ na anyị ji nkwadebe ahụ tụnyere otu usoro nke ihe eji eme ihe, ha bụ otu na-egosipụta ya. N'otu oge ahụ, a na-agbanwekwa etu esi eme ihe nke ọgwụ ọgwụ, dịkwa ka ọkara ndụ nke ihe ndị na - arụ ọrụ. Dika ike iji nweta oke arụmọrụ kachasị, ọgwụ ndị a yikwara.
Enwere ike dochie Cardiomagnyl na Phasostabil?
Ihe ndị a bụ ngwaọrụ ndị na-agbanwe agbanwe. Agbanyeghị, n'ọnọdụ ebe onye ọrịa ahụ zụlitere mmetụta na-adịghị mma maka akụkụ nke ọ bụla na Cardiomagnyl, enweghi ike iji Phazostabil, ebe ọgwụ abụọ ahụ nwere otu ọgwụ.
Ndi dibia nyocha
Kartashova S.V., akwara gbasara obi, 37 dị afọ, Tambov
A na-edenye Cardiomagnyl ọtụtụ oge maka ndị ọrịa gbagoro afọ 40. Ngwá ọrụ na-arụ ọrụ nke ọma: ọ na-eme ihe fọrọ nke nta ka ọ bụrụ n'otu ntabi anya, Ọzọkwa, mmetụta ndị na-adịghị ahụkebe. Ọ bụrụ na ị na-agbaso atụmatụ enyere n'iwu n'oge usoro ọgwụgwọ, yabụ nsogbu agaghị ebilite.
Maryasov A.S., dọkịta na-awa ahụ, dị afọ 38, Krasnodar
Phasostabil dị ọnụ ala karịa Cardiomagnyl, mana ụkpụrụ nke ịrụ ọrụ bụ otu. Ọgwụ abụọ ahụ dị irè. Agbanyeghị, ọ bụrụ na iji ogologo oge dị mkpa (dịka ọmụmaatụ, iji belata nchịkọta platelet ma gbochie ọbara ọgbụgba), ana m ahọrọ Phasostabilus n'ihi ọnụ ala dị ala.
Nyocha nke Ndidi maka Phasostable na Cardiomagnyl
Galina, 46 afọ, Saratov
Cardgwọ Cardiomagnyl bụ nkezi, mana afọ juru m na ngwa ọrụ a ma na arụmọrụ yana ogo mmetụta dị na afọ. Anaghị m anabata ọgwụ a nke ọma ruo mgbe enwere nsị. Maka nke a, anaghị m elele analogues ndị ọzọ, gụnyere mkpụrụ ndụ ihe nketa, ọbụlagodi na ha dị ọnụ ala.
Eugenia, afọ 38, St Petersburg
Maka m, Phasostabil bụ ngwá ọrụ kachasị mma na ụdị ya, n'ihi na ọ dị irè, ọ na-enyere aka iwepụ nnukwu ihe ịrịba ama nke nkụda obi.
