Plevilox bụ ọgwụ nje na - egbochi ọgwụ nje nke nwere ọtụtụ ihe dị iche iche sitere na otu fluoroquinolones nke ọgbọ nke anọ.
International Nonproprietary Aha
Moxifloxacin (Moxifloxacin).
Plevilox bụ ọgwụ nje na - egbochi ọgwụ nje nke nwere ọtụtụ ihe dị iche iche sitere na otu fluoroquinolones nke ọgbọ nke anọ.
ATX
Koodu ATX bu J01MA14, nke putara na ogwu ahu bu ndi otu ogwu na egburu egbu site na quinolone.
Ha weputara udi ya na ihe mebere ya
Ọgwụ dị n'ụdị mbadamba, nke ihe nkiri na-eme. Mbadamba mbadamba ahụ na igbe dị na kaadiboodu.
Ihe na - arụ ọrụ nke Plevilox bụ moxifloxacin hydrochloride na usoro nke ọgwụ mg 400. Microcrystalline cellulose, ssumum croscarmellose, lactose monohydrate, magnesium stearate, copovidone, polydextrose, polyethylene glycol, caplates na capric acid triglycerides, titanium dioxide, odo quinoline varnish na iron ironide na-eji ihe inyeaka.
Omume ọgwụ
Ọgwụ nwere ike igbochi topoisomerase IV na DNA gyrase - enzymes nke mere maka ịkpụgharị, ntụgharị, ndozi na ịchekwa DNA nke nje. O nwere mmetụta nke nje na-akpata n'ihi ikike nke moxifloxacin imebi njikọ DNA nke mkpụrụ ndụ microbial.
Ọgwụ dị n'ụdị mbadamba, nke ihe nkiri na-eme.
Na-arụ ọrụ megide micromgangan gram-gram na-adịghị mma, yana nje nke anaerobic, acid na-eguzogide ma na-efe efe, dịka Legionella spp., Chlamydia spp. na Mycoplasma spp. Ọ dị irè megide ụdị nje na-eguzogide ọgwụ beta-lactams na macrolides. Na-arụ ọrụ megide ọtụtụ ụdị nke microorganisms: gram-nke ọma nke staphylococcus aureus (gụnyere enweghị mmetụta maka methicillin), puloniae kọpaptococcus (gụnyere iguzogide penisilini na macrolides), A-group nke pyogenes pyogenes.
Mlọ ọgwụ
Eji ogwu ahu gosiputara n’omume di elu, n’agbanyeghi oge nri, ihe omuma nke bioavailability ya di ka 90-91%.
Otu nchịkwa ọnụ nke moxifloxacin na-enye gị ohere inweta Cmax n'ọbara nke 3.1 mg / l, n'ime nkeji 30 - awa anọ.
Pharmacokinetics bụ ahịrị na usoro onunu ogwu nke 50-1200 mg yana ọgwụ ụbọchi iri, ya na 600 mg / ụbọchị.
Ebe kachasị dị n'ị ofụ ọgwụ ahụ bụ ngụgụ, alveolar macrophages, akpụkpọ ahụ mucous nke sinuses na bronchi.
Enwere ike ịgwụ ọgwụ ahụ dịka ngwaahịa metabolic na-adịghị arụ ọrụ yana n'ụdị ya mbụ yana mmamịrị na feces.
Okike nwoke na afọ anaghị emetụta oke ọgwụ pharmacokinetic (enwebeghị ule ụmụaka), ọ naghị emetụta nsị akụrụ.
Ihe ngosi maka ojiji
Edere ọgwụ ahụ maka ọgwụgwọ nke ọrịa na-emetụta akụkụ ahụ na elu akụkụ okuku ume: nnukwu nje sinusitis, pneumonia nke obodo na-enweta na ịba ụba nke bronchitis na-adịghị ala ala. Ọzọkwa, ọgwụ ahụ na-egosi arụmọrụ dị elu n'ịgwọ ọrịa nke anụ ahụ na anụ ahụ dị nro.
Ihe ngbanwe
Amachibidoro iji ya na ụmụaka na ndị nọ n'afọ iri na asatọ, na mkpokọta, n'oge afọ ime, lactation na hypersensitivity na moxifloxacin yana ndị ọ bụla na-eme nchọpụta na Plevilox.
Jiri nlezianya
Ntinye uche kachasị na nhọpụta nke Plevilox chọrọ akụkọ ihe mere eme nke ọrịa nkwarụ, ọrịa imeju, ogologo oge QT, bradycardia, myocardial ischemia, afọ ọsịsa na pseudomembranous colitis.
Amachibidoro ọgwụ a maka iji ya na ụmụaka yana ndị gbara afọ 18 gbakoro.
N'ihi ahụmịhe ezughi oke na ngwa ahụ na ọmụmụ ihe na-aga n'ihu, ịkpachara anya chọrọ ịdebanye ọgwụ maka ndị ọrịa na-arịa ọrịa metụtara ọrịa. N’ime ọgwụgwọ ya na glucocorticosteroids na ọgwụ na-ebelata ịdị ure nke akwara obi (antiarrhythmics, tricyclic antidepressants, antipsychotics), ọ dị mkpa inyocha ọkachamara.
Otu esi ewere Plevilox
Were ọnụ ugboro 1 kwa ụbọchị na usoro onunu ogwu nke 400 mg. Oge ọgwụgwọ ọ dabere na ọrịa a:
- na ọkwa nke iwe na-adịghị ala ala nke ụkwara akwara - ụbọchị ise;
- ya na oria nke anakpo obodo - ubochi iri;
- nwere nnukwu sinusitis, ọrịa nke anụ ahụ na anụ ahụ dị nro - ụbọchị asaa.
Na-arịa ọrịa shuga
Nnyocha e mere egosiwo na ọgwụgwọ fluoroquinolone na-abawanye ohere nke mmetụta ndị ọzọ na ọrịa shuga mellitus, na mmepe nke dyslexemia. A na-atụ aro ịhọpụta ọgwụ nje maka klaasị ndị ọzọ: beta-lactams na macrolides.
Agbanyeghị, n'ọnọdụ ụfọdụ (dịka ọmụmaatụ, yana ọrịa nje na njiri mara ndị ọrịa shuga), iji ọgwụ a zie ezi. N’ịwa ahụ, ọrịa ndị dị otú ahụ bụ ihe na-ebutekarị mgbatị ahụ na-abụghị traumatic, ebe a na-elebara ntị zuru oke na ọgwụgwọ ọgwụ nje zuru oke (gụnyere ọgwụ ndị nwere moxifloxacin).
Ọgwụ Plevilox na-abawanye ohere nke nsonaazụ mmetụta nke ọrịa shuga.
Nsonaazụ Pleviloksa
Site na anụ ahụ na akwara
Ikekwe ọdịdị nke ihe mgbu na azụ, mmepe nke arthralgia na myalgia.
Ọkpụkpụ afọ
Nsonaazụ si eriri afọ ana-egosipụta site na mgbu afọ, ọgbụgbọ, afọ ọsịsa, ọgbụgbọ, ọnyụnyụ ọbara, ọgbụgbọ, afọ ntanetị, ịba ụba nke ọrụ ịba ọcha n'anya, mwepụ nke ihe ụtọ.
Ahụhụ Hematopoietic
Enwere ohere nke ịmalite leukopenia, eosinophilia, thrombocytosis, thrombocytopenia na anaemia.
Sistemụ akwara Central
A na-egosipụta nsonaazụ ndị sitere na sistemụ akwara etiti n'ụdị ọgbụgba, ọgba aghara ụra, ụjọ jijiji, nchekasị, asthenia, isi ọwụwa, ịma jijiji, paresthesia, mgbu ụkwụ, ihe mgbu, ọgba aghara na ọnọdụ nkụda mmụọ.
A na - egosipụta nhịahụ nke Plevilox sitere na sistemụ akwara na-esite n'ụdị ọgbụgba.
Na anụahụ
Rashes na anụ ahụ, n'ọnọdụ ndị adịkarịghị, ọnya afọ nwere ike.
Site na usoro mkpụrụ ndụ ihe nketa
Enwere ihe ize ndụ nke candidiasis na vaginitis.
Site na usoro akwara obi
Enwere ike ịbawanyewanye n'ọbara ọbara, ihe omume nke tachycardia, akụkụ ụbụrụ, palpitations na mgbu mpaghara mpaghara obi.
Ahụhụ
A chọpụtara mmeghachi omume nfụkasị n'ụdị itching na ihe ọkụ ọkụ, ikpe nke ujolactic ujo dị ụkọ. Na infusion, mmeghachi omume mpaghara nwere ike ime: ihe mgbu na ntinye ahụ, ọzịza na mbufụt.
Mmetụta ikike ịchịkwa usoro
Mgbe ị na-a theụ ọgwụ ahụ, enwere ike inwe ahụ erughị ala na oke nfe, n'ọnọdụ ndị a, a naghị akwado njikwa usoro.
Mgbe ị na-a theụ ọgwụ ahụ, enwere ike inwe ahụ erughị ala na oke nfe, n'ọnọdụ ndị a, a naghị akwado njikwa usoro.
Ntụziaka pụrụ iche
Jiri na agadi
Mgbe afọ 60 gachara, ihe ọghọm nke akwara afọ na akwara na-abawanye (Achilles tendon, ntụgharị nke nkwonkwo ubu, akwara aka, biceps, isi mkpịsị aka, wdg). Mgbe ihe ịrịba ama mbụ nke ụdị dysfunctions ndị ahụ pụtara, onye ọrịa ahụ kwesịrị izu ike zuru ezu na ụdị ọgwụgwọ ndị ọzọ na-eji ọgwụ na-abụghị quinolone.
Inye umuaka
N'ihi nchekwa nchekwa na arụmọrụ nke ọgwụ ahụ ekwenyeghi na nwata, oge uto na ndi ntorobịa (ruo afọ 18 na mkpokọta). Ekwesiri iburu n'uche na ihe omumu emere gosiputara ihe ndabere nke ihe arthropathy na ọgwụgwọ nke moxifloxacin ọgwụ nwere.
Jiri n'oge ime na lactation
Ọrịa Plevilox ga-ekwe omume n’ebe ụmụ nwanyị dị ime nọ, ma ọ bụrụ na ịdị uchu ya ga-adị elu karịa ihe nwere ike ibute nwa ebu n’afọ, ebe ọ bụ na emebebeghị ọmụmụ ihe zuru oke ma jisie ike.
N'oge a na-enye nwa ara, a ga-ewepụ Plevilox nchịkwa.
N'oge a na-enye nwa ara, Plevilox kwesịrị ka ewezuga ya, ebe ọ bụ na egosiri na ọ nwere ike ịbanye na mmiri ara ara yana mmetụta na-esote mmetụta na-esote ụmụaka.
Ngwa maka ọrụ ezughi oke ọrụ
Na ọdịda akụrụngwa, jiri ịkpachapụ anya.
Jiri maka ọrụ imeju na-arụ ọrụ
Ọdịda imeju na ọkwa dị elu nke transaminases bụ contraindications maka nchịkwa nke moxifloxacin n'ihi ahụmịke na-adakarị.
Do Overụbiga Plevilox ókè
Onweghị nsogbu ọ bụla na-agbanwe agbanwe ka achọpụtara na otu ọgwụ ọgwụ yana ịta nke ihe ahụ n'ime 2.8 g.
Dodoụbiga mmanya ókè na-agwọ ọrịa na-egbu egbu site na iji mmanye ikuku na ojiji nke unyi na-arụ ọrụ. N'ọnọdụ ịdoụbiga ókè, a na-atụ aro maka ECG, ebe ọ bụ na ọ ga-ekwe omume ịgbatị oge QT. Dọkịta nwere ike ịkọwa ọgwụ Symptomatic.
A na-agwọkarị ọgwụ mgbochi Plevilox site na ịsacha afọ na iji unyi na-arụ ọrụ.
Mmekọrịta na ọgwụ ndị ọzọ
Ojiji nke antacids, mineral na multivitamins na-egbochi mmịpụta ma belata ịdị n'otu nke ihe na-arụ ọrụ na plasma. Na usoro ọgwụgwọ, a na-atụ aro oge ndị a:
- Mgbe awa 2 gachara Pleviloksa;
- 4 awa tupu mbanye.
Iji nkwonkwo mee ya na ọgwụ ndị ọzọ nke klas fluoroquinolone na-akwalite mmepe nke mmeghachi fototoxic.
Anakpo nnabata nke moxifloxacin banye n'ọbara ọbara ebe ị na-ewere ranitidine.
Mmanya ndakọrịta
A machibidoro ị useụ mmanya n'oge ọgwụgwọ na plevilox n'ihi ụba nke mmetụta ndị na-emetụta ya (nke kachasị site na sistemụ akwara etiti). Na mgbakwunye, ọrụ ethanol anaghị ekwe ka itinye uche nke ihe ọrụ dị n'ime ọbara ahụ chọrọ, nke na-emetụta arụmọrụ nke ọgwụgwọ.
Analogs
Ihe analogues nke ogwu bu:
- Avelox;
- Aquamox;
- Megaflox;
- Moxispenser;
- Moxiflo;
- Moxifloxacin;
- Rotomox;
- Simoflox;
- Ultramox;
- Heinemox.
Ahịa ọgwụ na-ahapụ okwu
Enwere m ike ịzụta na ndenye ọgwụ
Onweghị ọgwụ ọ bụla anaghị enye.
Ọnụahịa
Ọnụahịa maka ịkwakọ ọgwụ Russia mere (5 mbadamba 5) na-amalite na 500 rubles.
Ọnọdụ nchekwa maka ọgwụ
Chekwaa ya na ebe gbara ọchịchịrị, nke e chebere site na mmiri, na okpomọkụ agaghị akarị + 25 Celsius.
Bọchị mmebi
Ruo afọ 2 na nchekwa kwesịrị ekwesị.
Emeputa
A na-ere ire ere nke ndị na-emepụta Russia na ndị India: Farmasintez OJSC (Irkutsk) na Plethiko Pharmasyyutikalz Ltd (Indore).
Nyocha
Sophia, onye gbara afọ 24, Krasnodar
Ejiri m sinusitis nnukwu ọgwụ a, ọ nyeere aka ngwa ngwa. Naanị otu ngwá ọrụ nke mechara bụrụ ihe bara uru, tupu nke ahụ, na ọgwụ ọzọ ejiri ọgwụ nje ndị ọzọ mee ihe.
Ivan, dị afọ 46, Kazan
Enwere mmetụta dị egwu n'akụkụ ọgwụ a. Isi ọwụwa, ehighị ụra nke ọma, ọgbụgba pụtara. Echere m na m ga-eji ya mee ihe, were ụbọchị 3, mana enweghị ndozi. Agakwuuru m dọkịta iji bulie ihe ọzọ, mgbe m mechara jiri ntụpọ Aquamox dochie ya, mgbaama niile wee pụọ.
Dmitry, onye gbara afọ iri atọ na ise, Lyantor
Enwere m ike ịgwọ ọrịa bronchi na-adịghị ala ala naanị na plevilox. N’obodo anyị, o siri ike inweta ya, nye ya iwu site na Surgut, mana ọ dịghị akwa ụta na ya, ebe ọ bụ na nsonaazụ ahụ pụtara ozugbo.
Marina, dị afọ 36, Vladivostok
Dọkịta ahụ nyere ọgwụ a maka ọrịa sinusitis nke ukwuu, kwuru na ya kwesịrị iji nlezianya nyochaa ngosipụta nke mmetụta ndị ọ na-akpata, ebe ọ bụ na edepụtara usoro ọgwụgwọ n'oge ime. Ọ dị mma na m dọrọ aka ná ntị, n'ihi na ọgbụgba ahụ siri ike karị, mana m ga-eche na ihe ndị a bụ ngosipụta nke toxicosis. Ya mere, dochie anya usoro ọgwụgwọ ozugbo, ihe niile gara nke ọma.
