Cholesterol dị elu na-emetụta ahụ ike. Iji belata ya, ndị otu ọgwụ ọgwụ na-eme ka mmadụ na-eme ka uru ọ bara daa.
Edere ha dabere na ụdị ọrịa ahụ na njiri arụ ọrụ nke ahụ.
Otu dị iche iche na nhazi ọkwa
A na-edobe kọlestrọl ahụ n'ahụ ma debe ya na mgbidi arịa ọbara.
Ọtụtụ mgbe, nke a na-eduga n'ọbara obi, nkụchi obi na ọrịa strok. Ejiri ọgwụ dị iche iche iji belata abụba abụba.
Ndepụta a gụnyere:
- Statins bụ ndị na - egbochi enzyme na - etinye aka na mmepụta cholesterol.
- Niacin - belata LDL, belata ihe ize ndụ nke egbochi mkpụkọ ọbara.
- Ọgwụ nke na - eji nwayọ nwayọ - kwụsị ịmịnye cholesterol na eriri afọ, mwepụta ya n'ime ọbara.
- Fibroic acid bụ ọgwụ iji belata triglycerides ọbara.
- Ndị na - eme ntụpọ nke bile acid - na - ewepụ oke elele na - adị n'ahụ ahụ.
Usoro ọgwụgwọ ọ bụla nwere njirimara nke ya, contraindications na nsonaazụ ya ma edee ya dabere na akụkọ onye ọrịa na usoro nyocha.
Statins, ihe ha na ngwa ha
Statins bụ ọgwụ na-ebelata cholesterol. Ihe ha mere bu igbochi enzyme, nke na-akpasu iwe na mmepe nke LDL (cholesterol ojoo).
A na-anọchite anya Statins site na ọgbọ anọ, a na-ahụ nke ikpeazụ ka ọ kacha arụ ọrụ. Aha ahụike bụ HMG-CoA reductase inhibitors.
N'ime imeju, a na-ebelata cholesterol njikọ, na ọbara, mbelata nke ego.
Otu ọgwụ ọgwụ ahụ na - eme ka ịdị mma ọbara dị mma, na - eme ka ọnọdụ nke arịa ọbara, na - egbochi thrombosis na plahe atherosclerotic. Mgbe ị na-ewere statins, enwere ike belata ntakịrị na ọkwa shuga. Isi ihe bụ igbochi mmepụta enzymes imeju.
Site n'iji statins eme ihe, enwere mbelata cholesterol site na nkezi 40%. Eji gbochie strok na nkụchi obi. A na-eji ya maka hypercholesterolemia, atherosclerosis, ọrịa obi. Statins nwere mmetụta na imeju.
Mgbe ị na-eji ọgwụ ọjọọ eme ihe, a na-enyocha ọgwụ biochemistry.
Vidiyo si na Dr. Malysheva banyere akpụ:
Otu n'ime ngosipụta ndị dị njọ kwuru:
- isi ọwụwa, ehighị ụra nke ọma;
- mmeghachi omume akpụkpọ ahụ nfụkasị;
- mbelata libido;
- ogwe akwara;
- itinye uche na ncheta;
- eriri afọ;
- thrombocytopenia;
- imebi imeju;
- myopathy.
Contraindications maka ojiji:
- mẹkpoo mkpụkpu;
- ime
- mkpụkpu akụrụ;
- afọ ruo afọ 18;
- inye ara;
- anabataghị ọgwụ ndị dị na ọgwụ ahụ.
A na-anọchite anya Statins site na ụzọ ndị a: Zokor, Lipostat, Rovakor (ọgbọ nke 1), Leskol (ọgbọ nke abụọ), Atoris, Tulip, Lipobay (ọgbọ nke atọ), Rosuvastin, Krestor, Akorta (ọgwụ ọhụụ).
Fibroic acid
Ngwunye nke fibroic acid - klas nke ọgwụ emepụtara iji dozie metabolism lipid. Ha na-ebute ọkwa nke abụọ nke arụmọrụ ma ama ama mgbe emume.
Ọgwụ nke izi otu a bụ clofibrate. Taa, ọtụtụ mba adịghị eji ya n'ihi nsí ya dị elu na nsonaazụ ya. Mgbe nke ahụ gasịrị, a malitere iji Bezafibrates, Cyprofibrates na Fenofibrates.
Ebe ikpeazu kachasi nma. Ha nwekwara ike ịchịkwa shuga ọbara, ọkwa nke uric acid dị ala. Nke a bụ eziokwu karịsịa maka ndị ọrịa nwere ọrịa shuga na gout n'otu oge.
Isi mmetụta nke acid bụ na ha gbanwere usoro nke lipid metabolism. Ngwakọta ọrụ na-arụ ọrụ na-ebelata LDL, na-abawanye HDL, ma na-eme ka metabolism dị ọcha.
Na-ewusi mgbidi nke arịa ọbara, na-abawanye ike ịba ụba, na-egbochi nguzobe. Ọ na-egbochi ịmịnye ọbara. N'okpuru mmetụta nke fibrates, njikọ nke triglycerides na-ebelata, nkewa na mgbochi nke uto LDL na-eme ngwa ngwa. Medicationsakingụ ọgwụ na-ebelata ihe ize ndụ nke ọrịa obi obi. Otu ìgwè ọgwụ nwere mmetụta bara uru na steeti sistemụ akwara obi.
Ihe ngosi maka ojiji bu:
- ọrịa shuga;
- cholesterol dị elu (na njikọta ọgwụgwọ);
- nnukwu olu nke triglycerides;
- teke ono;
- gout
- oke ibu
- metabolic syndrome.
Ekwesịrị ịkpachara anya na ijikọta fibrates na ọgwụ ndị ọzọ. Nke a nwere ike iwelie mmetụta ọjọọ na akụrụ na umeji.
Otu nsogbu ndị a na-ahụta:
- eriri afọ;
- arụ ọrụ ezumike;
- isi ọwụwa
- mmeghachi omume nfụkasị ahụ;
- mụbaa n'ime hepatic egosi;
- imebi imeju;
- nsogbu ụjọ.
Ihe ndị bụ isi maka ojiji nke fibrates:
- mẹkpoo mkpụkpu;
- afọ ime na lactation;
- ọdịda odida;
- alisụrụma;
- n'ọbara;
- iṣiro nke cholecystitis;
- afọ ruo afọ 18;
- cholelithiasis.
Ọgwụ ndị nwere oke nlezianya kwesịrị ka ndị okenye jiri ya.
Ndị na - eme usoro nke bile acids
Nandị na - eme ihe nkwụghachi nke acid bile - otu ọgwụ metụtara ọgwụ Lipid na-agbada. Ha bụ ọgwụ ancillary iji belata cholesterol ọbara mgbali elu.
Isi ihe a na-eme bụ njikọta nke bile acid na excretion ọzọ na-esote ya, na -eme ka mmepụta cholesterol dị. Ihe nọ n'ọrụ jikọtara acid na ikewapụta ya.
A na-egbochi mmịcha nke bile. Enyere njikọ nke HDL, ana - ewepụta LDL site n'ọbara. Na mgbakwunye, haemoglobin na glycosylated na glucose na-ebelata na ndị ọrịa nwere ọrịa shuga.
A gwaghị ọgwụ gwọọ n’ime eriri sisitemu, ha na-apụ n’eriri. N'akụkụ a, mmepe nke mmetụta ndị belata na-pere mpe. A na-ahụkarị ihe na-adịghị mma dị na eriri afọ - afọ mgbu, ọnya afọ, afọ ntachi na ịmịcha ọbara, mgbanwe na-atọ ụtọ.
N'ihe dị ukwuu, ndị na-eso ụzọ nwere ike belata mmịkọta nke B6 na vitamin na-abụ abụba D, A, K, E. E nwere ihe ọghọm nke ọbara ọgbụgba n'oge ị withụ ọgwụ site na mkpụrụ ndụ mucous mebiri emebi, ka ọbara coagulation na-ebelata.
N'oge ọgwụgwọ FFA, cholesterol na-emerụ ahụ dị ihe dị ka 45%, steeti akwara ahụ na-emewanye 20%. Ogologo oge eji abawanye cholesterol bara uru. A na-enweta mmetụta hypocholesterolemic na nkezi mgbe ọnwa nke nchịkwa gasịrị. N'ime usoro ọmụmụ ahụ, a na-ekpebi mmetụta dị mma nke FFA na ọrịa obi na ọrịa ha kpebiri.
Aha ọgwụ: Colestipol, Cholestyramine.
Ihe ngosi maka ojiji:
- obi ọgụ;
- Ọrịa obi obi Ischemic;
- ọrịa dyslipidemia;
- atherosclerosis;
- hypercholesterolemia;
- nsogbu na akwara.
Iji nlezianya, a na-ewere mbadamba maka ịmịnye afọ, cholelithiasis.
Contraindications FFA gụnyere:
- phenylketonuria;
- mmeghachi omume mmetụta;
- hypertriglyceridemia;
- igbochi traktị biliary;
- ọnya afọ;
- nsogbu ọbara ọgbụgba;
- afọ ntachi;
- igbochi billiard;
- hyperlipoproteinemia nke ụdị III na IV.
Ọgwụ na-emetụta nnabata afọ. Nweta kachasị mma bụ otu awa ma ọ bụ awa 4 mgbe nri gasịrị. Nke mbụ edepụtara na obere usoro, mgbe ahụ, a na-eji nwayọọ nwayọọ bulie dose ahụ. Usoro dị otú a na-ebelata mmepe nke mmetụta ndị ọzọ.
Ndị na-achọ ọgwụ na FA na-emetụta nnabata nke ọtụtụ ọgwụ. Ndị a gụnyere ọgwụ mgbochi penisillin, ọrịa diuretics, ihe mgbochi adrenergic. N'ime usoro ọgwụgwọ ogologo oge, a na-enye biochemistry iji nyochaa ndị na-egosi ihe.
Ọ pụtara na a ga - egbochi ihe cholesterol na eriri afọ
Ọgwụ ndị na-egbochi itinye cholesterol n'ime eriri afọ na-ebelata nnabata iji belata itinye uche ya na ọbara.
Otu ọgwụ a gosipụtara gụnyere Lipobon, Ezetrol, Tribusponin, Guarem. Anaghị etinye ha n'ọbara, ha na ọgwụ ndị ọzọ jikọtara nke ọma, n'adịghị ka FFA, ha anaghị eme ka ihe nzuzo nke bile acid ghara ịba ụba.
N’ihi ya, mgbe ụbọchị iri nke ị ofụ ọgwụ ọjọọ ahụ gasịrị, a na-eji 50% belata nnabata cholesterol. N'otu oge nri ị na-eme adịghị emetụta bioavailability nke ọgwụ ndị otu a gosipụtara. N'ime usoro ịchọrọ ọkwa cholesterol belatara ruo 20%.
Ihe ngosi maka ojiji:
- Hyzycholesterolemia homozygous familialia;
- isi hypercholesterolemia;
- enweghi ike nke statin monotherapy;
- homozygous sitosterolemia.
Ejiri ya na usoro ọgwụgwọ nri, na enweghị mmetụta, a na-ejikọta ha na statins. A na-ejikarị ndị na-eme ihe na-edozi ahụ bụ Essentiale, Lipostabil.
Otu n'ime contraindications maka:
- afọ imeju;
- anabataghị ume ma ọ bụ ụkọ nke lactose;
- mmeghachi omume mmetụta;
- afọ erughi afọ 18;
- n'otu oge eji fibrates.
Otu n'ime nsogbu ndị a chọpụtara:
- bloating;
- mẹ ivu;
- nsogbu ọnya (afọ ntachi na afọ ọsịsa);
- arụ ọrụ nke imeju;
- ike ọgwụgwụ
- isi ọwụwa.
Nicotinic acid
Acid Nicotinic bụ vitamin a na-agwakọta mmiri dị mkpa maka ahụ mmadụ. Mmetụta ọgwụgwọ: iwetulata cholesterol na ụmụ irighiri ihe egbugbere ọnụ, vasodilation.
Ọ na-egbochi mmepe nke ọrịa obi, na -eme ka ọ dị mma ma na-eme ka ihe dị jụụ.
Mgbe etinyere ya, a na-atụgharị nicotinic acid ka ọ bụrụ nicotinamide a na-arụ ọrụ. Ọ na-etinye aka na usoro metabolic nke vitamin, usoro sịntetik, iku ume anụ ahụ.
Ihe ahụ na - eme ka microcirculation dịkwuo mma, na - ahụ maka lipoproteins, belata LDL na triglycerides, ma na - abawanye HDL. Ọ bụ metabolized na imeju, kpụrụ ya akụrụ. Oke ruru ịta ihe ahụ erute mgbe nkeji iri anọ na ise gachara.
Ndepụta ọgwụ: Enduracin, Niceritrol, Acipimox. Ngwakọta Nicotinic acid dị ọnụ ala ma dị ọnụ ala maka ọtụtụ mmadụ.
Ihe ngosi maka ojiji:
- ọkwa mbụ nke hyperlipidemia;
- ọghọm nke ụbụrụ;
- ụkọ vitamin PP;
- ogologo oge nrụgide;
- atherosclerosis;
- n'oge ịhazigharị mgbe nkụchi obi na ọrịa strok gasịrị;
- microagniopathy;
- atherosclerotic cardiosclerosis;
- ọnya akpụkpọ ahụ mucous na akpụkpọ;
- angina pectoris;
- neuritis ihu;
- mẹ akpaa lẹ mkpụkpu;
- polyneuropathy na-arịa ọrịa shuga;
- enterocolitis, colitis, gastritis.
Contraindications maka ojiji:
- hypersensitivity na ihe ahụ;
- ọnyá afọ (afọ);
- afọ erughị afọ 2.
N'iji nlezianya mee, ndị mmadụ nwere ọrịa imeju, glaucoma, gout na-ewere ọgwụ ahụ.
Mmetụta ọghọm n'oge ọchịchị:
- A na-ahụta ọbara ọgbụgba nke imeju mgbe ị na-a theụ ọgwụ ahụ na oke doses;
- hypotension;
- Ngosiputa akpụkpọ ahụ nfụkasị;
- mmiri zoro ezo nke mmiri ọ gastụ gastụ gastric;
- ibelata nnabata glucose;
- mgbakasị ahụ mucosa gastric;
- imebi imeju;
- hyperemia nke anụ ahụ;
- ihe egwu nke ime myopathy mgbe ejiri ya na statins.
Additionalzọ ndị ọzọ
Na mgbakwunye na mgbazi ọgwụ, enwere ụzọ ndị ọzọ dị mma ma dị oke mma iji belata cholesterol. Ndị a gụnyere ezigbo ndụ obibi na nri. Ejiri obere mmụba na cholesterol mee ihe - ruo 18% nke ọpụrụiche.
Usoro mgbochi ndị yiri nke a gụnyere:
- mwepu nke ihe ojoo emerụ site na nri;
- mmega ahụ, nrụgide, mmega ahụ;
- na-a foodsụ obere nri cholesterol.
Iji belata LDL, a na-etinye nri nwere fiber na vitamin na nri. Ewepu abụba trans, anụ e ghere eghe na ọdụdụ, nri mkpọ, nri nke nwere nnukwu kọlestọrol. A na - enweta ihe akporo fiber n’ime ọtụtụ achịcha, ọka, ọka, akwụkwọ nri na mkpụrụ osisi.
Ọ dị mma iri nri na - eme ka cholesterol dị ala belata. Ndị a bụ ube oyibo, ọka, olive na sunflower. Akpukpo aru nke abuba na mmanu mmanu bu mmanu aru aru. Usoro eji ngwaahịa ndị a nwere ike belata LDL site na nkezi 10%. Ojiji nke lipoic acid na vitamin B nwekwara mmetụta dị mma na ndị na-egosi ya.
Ihe omimi vidio na nri ịbelata cholesterol:
Ogwu cholesterol na –eme ka otutu ihe di egwu. Edere ha na mgbagwoju anya na monotherapy, gosiputa ezi agwa mgbe ejiri ya rụọ ọrụ nke ọma. Ebumnuche nke ọgwụ ọ bụla kwesịrị ịbụ ihe ziri ezi.