A na-eji ọgwụ dị iche iche dabere n'ụdị ọrịa shuga.
Maka ụdị nke 1, a na-enye insulins ya, maka ụdị 2, ọkachasị mbadamba mbadamba.
Ọgwụ shuga na-ebelata Glucovans.
Ihe omuma banyere ogwu
Usoro usoro Metformin
Glucovans (glucovance) - ọgwụ dị mgbagwoju anya nke nwere mmetụta hypoglycemic. Ihe omuma ya bu ngwakọta nke ihe abuo na - aru oru nke ndi otu ogwu di iche iche nke metformin na glibenclamide. Nchikota a na - akwalite utịp.
Glibenclamide bụ onye nnọchi anya ọgbọ nke abụọ sitere na usoro sulfonylurea. Ghọtara dị ka ọgwụ kachasị mma na otu a.
A na-atụle Metformin dị ka ọgwụ nke mbụ, nke a na-eji na enweghị mmetụta nke usoro ọgwụgwọ nri. Ngwakọta ahụ, ma e jiri ya tụnyere glibenclamide, nwere obere ọrịa hypoglycemia. Nchikota nke ihe abuo a na - enye gi ohere inweta ihe a na - ezi anya ma mee ka oru aru ike di elu.
Omume nke ọgwụ ahụ bụ n'ihi ihe mejupụtara abụọ na - arụ ọrụ - glibenclamide / metformin. Dịka mgbakwunye, ejiri magnesium stearate, povidone K30, MCC, sodium croscarmellose.
A na-enweta ya na mpempe mbadamba na usoro abụọ: 2.5 mg (glibenclamide) +500 mg (metformin) na 5 mg (glibenclamide) +500 mg (metformin).
Omume ọgwụ
Usoro Glibenclamide
Glibenclamide - na - egbochi ụzọ chanel na - egbochi ọria akwara. N’ihi nke a, ịmịbara homonụ na-abawanye, ọ na-abanye n’ọbara ọbara na n’etiti ọmụmụ ihe.
Ofdị irè nke mkpali homonụ na-adabere na usoro eji eme ya. Belata shuga na ma ndị ọrịa nwere ọrịa shuga na ndị mmadụ.
Metformin - na-egbochi ịmịnye glucose na imeju, na-eme ka ịdị ọcha nke anụ ahụ rute hormone, na-egbochi nnabata nke glucose n'ọbara.
N’adịghị ka glibenclamide, ọ naghị akpali insulin njikọ. Na mgbakwunye, ọ na-enwe mmetụta dị mma na profaịlụ nke lipid - cholesterol mkpokọta, LDL, triglycerides. Adịbelata ọkwa shuga na mbụ na ahụike mmadụ.
Mlọ ọgwụ
A na-agbatị Glibenclamide n'agbanyeghị nri nri. Mgbe awa 2.5 gachara, ọ na-abanye n'ọbara ya kachasị n'ọbara, mgbe elekere asatọ gachara mbelata. Nkeji ọkara bụ elekere iri, kpochapụrụ kpamkpam bụ ụbọchị 2-3. Fọrọ nke nta ka metabolized n'ime imeju. A na-ewepụ ihe ahụ na mmamịrị na bile. Indtinye aka na protein ndị plasma agafeghị 98%.
Mgbe nchịkwa ọnụ gasịrị, metformin na-abanye kpam kpam. Nri na-emetụta nnabata nke metformin. Ka elekere abụọ 2.5 gachara, etinyetụ ọnụ ọgụgụ nke ihe ahụ; ọ dị ala n'ọbara karịa na plasma ọbara. Ọ bụ metabolized ma hapụ agbanweghị agbanwe. Oge iwepu ọkara ndụ bụ awa 6.2 A na - ewepụ ya na mmamịrị. Nkwurịta okwu na protein adịghị mkpa.
The bioavailability nke ọgwụ ahụ bụ otu ihe ahụ na ịnweta iche iche nke ihe ọ bụla na - arụ ọrụ.
Ihe ngosi na contraindications
Otu n'ime ihe ngosi iji were mbadamba Glucovans:
- Ọrịa shuga 2dị nke abụọ na enweghị ike ọgwụgwọ ọgwụ, mmega ahụ;
- Ọrịa shuga diabetesdị nke abụọ na enweghị mmetụta n'oge monotherapy na ma Metformin na Glibenclamide;
- mgbe ị na-eji dochie anya ọrịa glycemia dochie ndị ọrịa.
Ihe mgbochi iji:
- 1dị 1 ọrịa shuga mellitus;
- hyperensitivity na sulfonylureas, metformin;
- hypersensitivity na akụkụ ndị ọzọ nke ọgwụ;
- mkpụkpu akụrụ;
- afọ ime / lactation;
- ọrịa mamịrị ketoacidosis;
- ihe mgbochi;
- lactic acidosis;
- ịxụbiga mmanya ókè;
- nri hypocaloric;
- afọ ụmụaka;
- nkụchi obi;
- okpu iku ume;
- ọrịa na-efe efe siri ike;
- nkụchi obi;
- porphyria;
- arụ ọrụ ezumike.
Ntụziaka maka ojiji
Ndi dọkịta doziri usoro ogwu a, na-eburu n'uche ogo glycemia na njiri mara nke ahụ. Ná nkezi, usoro usoro ọkọlọtọ ahụ nwere ike isi kwekọọ na ndị enyere n'iwu. Mmalite ọgwụgwọ bụ otu ụbọchị. Iji gbochie hypoglycemia, ọ gafeghị ọgwụ metformin na glibenclamide guzobere na mbụ. A na-eme mmụba, ma ọ bụrụ na ọ dị mkpa, kwa izu abụọ ma ọ bụ karịa.
N'ihe banyere mbufe site na ọgwụ ọgwụ gaa Glucovans, enyere iwu ọgwụgwọ na-eburu n'uche usoro onunu ogwu ọ bụla na - arụ ọrụ ọ bụla. Ogologo ubochi guzosiri ike bu nkeji ano nke 5 + 500 mg ma obu 6 nkeji nke 2.5 + 500 mg.
A na-eji mbadamba mee ihe na nri. Izere glucose dị ala karịa n'ọbara, mee nri dị elu na carbohydrates oge ọ bụla ị theụrụ ọgwụ.
Vidiyo si na Dr. Malysheva:
Ndị ọrịa pụrụ iche
Edeghị ọgwụ ahụ n’oge nhazi na n’oge ime. N'ọnọdụ ndị dị otú ahụ, a na-enyefe onye ọrịa ahụ insulin. Mgbe ị na-eme atụmatụ ịtụrụ ime, ị ga-agwa dọkịta gị. N'ihi ụkọ data nyocha, na-enye ara, anaghị eji Glucovans eme ihe.
Edeghị ndị ọrịa agadi (> afọ 60) ọgwụ. A naghị atụ aro ka ndị na-arụ ọrụ ike maka ị takeụ ọgwụ. Ejikọtara nke a na ihe egwu dị elu nke lactic acidosis. Na megoblastic anaemia, ekwesiri iburu n’uche na ọgwụ na-agbadata ịnabata B 12.
Ntụziaka pụrụ iche
Jiri mkpachapụ anya na ọrịa nke thyroid gland, febrile ọnọdụ, adrenal insufficiency. Onweghị ọgwụ edepụtara maka ụmụaka. Anaghị anabata ndị glucovans na mmanya.
Usoro ọgwụgwọ a kwesịrị ijikọ usoro iji tụọ shuga tupu nri / mgbe nri gasịrị. A na-atụ aro ka ịlele itinye uche nke creatinine. Ọ bụrụ na arụ ọrụ ezumike ezumike na ndị agadi, a na-enyocha eleba anya ugboro atọ n'afọ. Site n'ịrụ ọrụ ahụ nkịtị, o zuru ezu iji nyocha otu ugboro n'afọ.
Oge awa 48 tupu / mgbe a wasịrị ya, a na-akagbu ọgwụ ahụ. 48 awa tupu / mgbe nyocha X-ray ya na ihe rediopaque, anaghị eji Glucovans.
Ndị nwere nkụda obi nwere nnukwu ihe ize ndụ nke ịmalite ọrịa akụrụ na hypoxia. A na-atụ aro ka esi arụ ọrụ obi na akụrụ ike.
Mmetụta akụkụ na ịdoụbiga mmanya ókè
Otu n'ime nsogbu ndị a na - eri n'oge a na - eri nri bụ
- ihe a na - ahụkarị bụ hypoglycemia;
- lactic acidosis, ketoacidosis;
- imebi uto;
- thrombocytopenia, leukopenia;
- ụba creatinine na urea n’ime ọbara;
- enweghi agụụ na ọrịa ndị ọzọ nke eriri afọ;
- urticaria na itching nke akpụkpọ ahụ;
- imebi ọrụ imeju;
- ịba ọcha n'anya;
- hyponatremia;
- vasculitis, erythema, dermatitis;
- nsogbu nke visual nwa oge.
N'ihe banyere njupụta nke Glucovans, hypoglycemia nwere ike ịmalite n'ihi ọnụnọ nke glibenclamide. Iwere glucose 20 g na-enyere aka ịkwụsị ngụgụ nke ogo oke. Ọzọkwa, a na-emezigharị usoro ọgwụgwọ, a na-enyocha ihe oriri. Ọrịa hypoglycemia siri ike chọrọ nlekọta mberede na ụlọ ọgwụ ga-ekwe omume. Over overụbiga mmanya ókè nwere ike ibute ketoacidosis n'ihi ọnụnọ nke metformin. A na-agwọ ọnọdụ yiri nke ahụ n'ụlọ ọgwụ. Mostzọ kachasị dị irè bụ hemodialysis.
Mmekọrịta na ọgwụ ndị ọzọ
Ejikọkwala ọgwụ na phenylbutazone ma ọ bụ danazole. Ọ bụrụ na ọ dị mkpa, onye ọrịa ahụ na-enyocha ike nke ọma. Ndị na - egbochi ACE belata shuga. Mmụba - corticosteroids, chlorpromazine.
A naghị atụ aro ka Glibenclamide jikọtara ya na miconazole - mmekorita dị otú a na-eme ka ihe ize ndụ hypoglycemia dịkwuo elu. Thenme ka usoro nke ihe ahụ dị kwere omume mgbe ị na-ewere Fluconazole, anabolic steroid, clofibrate, antidepressants, sulfalamides, homonụ nwoke, ikike nke coumarin, cytostatics. Homonụ ụmụ nwanyị, homonụ thyroid, glucagon, barbiturates, diuretics, sympathomimetics, corticosteroids na-ebelata mmetụta nke glibenclamide.
Site na nhazi nke metformin n’otu oge na akụrụngwa diuretics, enwere ike ibute lactic acidosis. Ngwakọta radiopaque mgbe a chịkọtara ọnụ nwere ike ịkpalite ọdịda akụrụ. Zere ọ bụghị naanị ị ofụ mmanya, kamakwa ọgwụ nwere afọ ojuju ya.
Ihe omuma ndi ozo, analogues
Ọnụahịa ọgwụ Glukovans dị 270 rubles. Ọnọdụ nchekwa ụfọdụ adịghị mkpa. Relelị site na ndenye ọgwụ. Ndụ shelf bụ afọ 3.
Mmepụta - Merck Sante, France.
Ihe analogue zuru oke (ihe mejupụtara na-arụ ọrụ) bụ Glybomet, Glybofor, Duotrol, Glukored.
Enwere ngwakọta ndị ọzọ nke ihe mejupụtara (metformin na glycoslide) - Dianorm-M, metformin na glipizide - Dibizid-M, metformin na glimeperide - Amaryl-M, Douglimax.
Iji dochie anya nwere ike ịbụ ọgwụ nwere otu ihe dị arụ ọrụ. Glucofage, Bagomet, Glycomet, Insufort, Meglifort (metformin). Glibomet, Maninil (glibenclamide).
Mmetụta Ndị Ọrịa mamịrị
Nyocha ndị ọrịa na-egosi ịdị irè nke Glucovans yana banyere ọnụahịa a na-anabata. Achọpụtakwara na ntụle shuga ka ị na-a theụ ọgwụ ahụ kwesịrị ịkarị.
Na mbu o were Glucophage, mgbe enyechara ya ndi Glucovans. Dọkịta kpebiri na ọ ga-akacha mma. Ọgwụ a na -ebelata shuga mma. Naanị ugbu a, anyị ga-agbanye ọtụtụ ugboro iji gbochie hypoglycemia. Dọkịta gwara m banyere nke a. Ihe dị iche n'etiti Glucovans na Glucophage: ọgwụ mbụ nwere glibenclamide na metformin, nke abụọ nwere naanị metformin.
Salamatina Svetlana, onye gbara afọ 49, Novosibirsk
Anọ m na-arịa ọrịa shuga kemgbe afọ asaa. N’oge na-adịbeghị anya, edere m ọgwụ ndị agwakọtara Glucovans. Ozugbo na uru: arụmọrụ, mfe nke iji, nchekwa. Ọnụahịa ahụ anaghịkwa ata ahụhụ - maka nkwakọ ngwaahịa m na-enye naanị 265 r, nke zuru ezu maka ọkara ọnwa. N'ime adịghị ike: enwere contraindications, mana abụghị m nke otu a.
Lidia Borisovna, 56 afọ, Yekaterinburg
Edere ọgwụ a maka nne m, ọ bụ onye ọrịa mamịrị. Na-ewere Glucovans ruo ihe dị ka afọ 2, ọ na-enwe mmetụta nke ọma, ahụrụ m ya na-arụ ọrụ ma na-enwe ọerụ. Na mbido, nne m nwere oke iwe - ọgbụgbọ na agụụ iri, mgbe ọnwa gasịrị ihe niile ga-apụ. Ekwubiri m na ọgwụ dị irè ma na-enyere aka nke ọma.
Sergeeva Tamara, 33 afọ, Ulyanovsk
Ebuuru m Maninil tupu, shuga nọ na gburugburu 7.2. Ọ tụgharịrị gaa Glucovans, n'ime otu izu shuga belatara ruo 5.3. Ejikọtara m ọgwụgwọ na mmega ahụ na nri ahọrọ. M na-atụ shuga ọtụtụ ugboro ma anaghị m ekwe ka ọnọdụ ndị dị oke njọ. Ọ dị mkpa ịgbanwere ọgwụ naanị mgbe ị nyochachara dọkịta, lelee usoro ọgwụgwọ doro anya.
Alexander Savelyev, 38 afọ, St. Petersburg
