Ọ bụghị mgbe niile ka enwere ike ijikwa ụdị ọrịa shuga nke ọrịa shuga 2 naanị site na enyemaka nke nri obere carb na ibu. Ọ dịkwa mkpa ịlụ ọgụ hyperglycemia, n'ihi na ọgwụgwọ agụghị akwụkwọ na-eduga na nnukwu nsogbu.
Otu n'ime ihe ndị kasị dị ize ndụ bụ ọrịa obi. Diabetalong (Latin Diabetalong), ọgwụ hypoglycemic nwere mgbatị ogologo ma ọ bụ gbanwee, ga - enyere aka belata ihe ize ndụ nke ịmalite CVD.
Ohere nke ọgwụ ọgwụ
Njirimara nke ọgwụ antidiabetic nke ọgwụ ahụ bụ n'ihi gliclazide na-arụ ọrụ. Mbadamba ahụ nwere 30 ma ọ bụ 60 mg nke ihe ndị bụ isi na ihe ndị nwere ya: calcium stearate, hypromellose, talc, lactose monohydrate, sillofon silikon dioxide.
Diabetalong bụ ọgwụ nke klaasị nke anọ na klaasị sulfonylurea. Mgbe ọ banyere n'ọbara, gliclazide na-akpali njikọ nke homonụ endogenous site na mkpụrụ ndụ nke pancreas, na-eme ka ịbawanye uru nke glucose (na-eme ka ọrụ glycogen synthase na-arụ ọrụ). N'ime ụbọchị ole na ole site na mmalite nke usoro ahụ, glycemic profaịlụ na-ahaziri. Oge etiti oge site na ntinye nri na ngịga diges na imepụta insulin na-emebi emebi, a na-ebelata ihe ngosipụta nke nri na-akpalite.
Ọ bụ ihe na-achọsi ike na afọ 2 mgbe ị theụsịrị ọgwụ ahụ, a na-enwe ike ịbawanye uru nke postprandial insulin na C-peptide. Mmetụta anụ ahụ na Diabetalong dị mgbagwoju anya:
- Na -emezi usoro metabolism;
- Ọ nwere mmetụta antioxidant systemic;
- Na-akpali insulin insulin;
- Ọ nwere mmetụta haemovaskụla (na-egbochi nchịkọta platelet).
Mgbe glucose abanye n’afere ọbara, gliclazide na-eme ka insulin rụpụta ọrụ ngwa ngwa. Site n'ịgwọ ya mgbe niile, ọgwụ ahụ na-adọ aka ná ntị:
Ọrịa microvascular - retinopathy (usoro mbufụt na retina) yana nephropathy (ezighi ezi na akụrụ);- Nsonaazụ Macrovaskụla - ọnya, nkụchi obi.
Ọrịa microvascular - retinopathy (usoro mbufụt na retina) yana nephropathy (ezighi ezi na akụrụ);Njirimara nke Pharmacokinetic
Site na afọ, a na-etinye ọgwụ ahụ n'ụzọ zuru ezu. Ọdịnaya kachasị n’ime ọgbụgba ọbara erutela kemgbe awa 2-6, yana maka mbadamba nwere MV - awa 6-12.
Mmetụta ọgwụgwọ ahụ na-adịgide 24 awa, protein glycazide na-edozi ọbara na-ejikọ aka 85-99%. N'ime imeju, a na-agbanwe ngwaahịa ndu ka ọ bụrụ metabolites, otu n'ime ha nwere mmetụta dị mma na microcirculation. Ọkara ọkara bụ awa 8-12, maka mbadamba nkume ndị nwere MB - awa 12-16. Ọgwụ 65% nwere mmamịrị, ọgwụ jiri okpukpo 12% nweta ọgwụ ahụ.
Onye gosiputara ogwu ahu
Ihe kpatara nhọpụta Diabetalong bụ ọrịa shuga 2dị nke Abụọ, ma dị ka monotherapy yana yana insulin ma ọ bụ ndị yiri antidiedi.
Ihe mgbochi na mgbochi
- Ọrịa shuga ;dị 1;
- Ntinye obi;
- Pathology nke imeju;
- Nsogbu akụrụ gbasara akwara;
- Ketoacidosis;
- Hyporthyroidism;
- Ọrịa shuga ma ọ bụ coperosmolar coma;
- Ime na inye nwa ara
- Nnukwu ọnya na ọkụ.
Diabetalong dị n’ime ụmụ nwanyị dị ime, ọ bụrụ na-enweghị ike ịkagbu ya mgbe ọ na-a breastụ ara, a ga-atụgharị nwatakịrị ahụ na nri aka nwa.
Anabataghị iji glycoside mgbe ejiri otu obere miconazole mee ihe.
Nsonaazụ
Ihe na-achọghị ka akwara na akwara afọ nwere ike ịbụ nkwarụ na-emetụta ụdị nke ọgbụgbọ, ọgbụgbọ, mgbu afọ. Site n'akụkụ nke metabolism, hypoglycemia ga-ekwe omume, maka usoro mgbasa - eosinophilia, cytopenia, anaemia. N'akụkụ nke anụ ahụ, enwere ike ịrịa nfụkasị na nyocha ya. Site na akụkụ ahụ ndị nwere mmetụta, enwere mgbakasị uto, isi ọwụwa, ọnwụ nke nhazi, ike gwụ.
Mkparịta ụka ọgwụ ọjọọ
A na - eme ka arụ ọrụ nke glycoside dịkwuo mma site na iji steroid anabolic, ndị mgbochi ACE, β-blockers, cimetidine, fluoxetine, salicylates, MAO inhibitors, Flucanazole, Pentoxifylline, Miconazole, Theophylline, Tetracycline.
Ohere nke glycoside na-esighi ike mgbe ejiri ya na-eji cobiturates, glucocorticoids, sympathomimetics, saluretics, rifampicin, ọgwụ mgbochi ọmụmụ, estrogens.
Otu esi etinye
Ekwesịrị iji Glycloside nweta nri. Erere mbadamba ihe nile, eji miri rutu ya dika miri. Ihe endocrinologist choputara usoro ogwu ya na usoro ọgwụgwọ ya n’otu n’otu, n’iburu n’usoro banyere oria ya na mmeghachi omume nke ndi oria shuga na ogwu. Maka ọgwụ Diabetalong, ntuziaka maka iji ya na-atụ aro ịmalite mbido nke 30 mg na mgbakwunye mgbakwunye na ụzọ nke mmụba (ma ọ bụrụ na ọ dị mkpa).
Iji nweta oke ọgwụgwọ ọgwụgwọ kachasị, ọ dị mkpa ịgbaso iwu dị mfe.
- A na-ewere ọgwụ kwa ụbọchị otu ugboro, nke kachasị mma - n'ụtụtụ;
- Enwere ike idozi ọnụọgụ ọgwụ ahụ n'ime 30 -120 mg / ụbọchị;
- Ọ bụrụ na oge nnabata ga-efu, iwu ekwesịghị ịgbanye ugboro abụọ na ụbọchị ọzọ;
- Mgbe ị na-agbakọ ọnya, dọkịta na-eburu n'uche agụ nke mita na HbAlc.
Site na arụmọrụ na-ezughi oke, a na-abawanye usoro ahụ (mgbe ya na dọkịta kwechara), mana ọ bụghị tupu otu ọnwa ka ewere ọgwụ glycoside nke mbụ. Kwa izu abụọ, na-akwụghị ụgwọ glycemia na-ezughi ezu, ị nwere ike ịbawanye dose ahụ.
Ọ dị mkpa ịtụle na mbadamba 1 nke Diabetalong PV nwere 60 mg nke glyclazide, nke a kwekọrọ na mbadamba 2 nke Diabetalong MV 30 mg nke ọ bụla.
Mgbe ị na-ebufe onye na-arịa ọrịa shuga na gliclazide site na ọgwụ hypoglycemic ndị ọzọ, nkwụsịtụ adịghị mkpa, belụsọ maka usoro sulfonylurea. Uzo mbu na nke a bu ezi - 30 mg, ma oburu na endocrinologist edeputara usoro ya.
N'ime usoro ọgwụgwọ dị mgbagwoju anya, a na-eji Diabetalong na ụdị insulin, biagudins, α-glucosidase inhibitors mee ihe. N'iji nlezianya mee ọgwụ, a na-enye ndị ọrịa shuga ọgwụ ahụ site na otu nsogbu ahụike hypoglycemic (ị alcoholụbiga mmanya ókè, ọrụ siri ike ma ọ bụ egwuregwu, agụụ, ndabere dị oke egwu). Ọkpụkpọ Hematopoietic na-etisa site na mmepe anaemia, thrombocytopenia, leukopenia, granulocytopenia.
Nchedo nchekwa
Iji zere hypoglycemia, ọ dị mkpa iji oge eji ọgwụ eme ihe maka iri nri, igbochi nnukwu nkwụsịtụ na nri, iji kwụsị kpamkpam ị ofụ mmanya na-aba n'anya. Oge nlekọta nke ckers-blockers nwere ike imegharị ihe ịrịba ama nke hypoglycemia.
Enwere ike ịmata ọnọdụ hypoglycemic site na isi ọwụwa, nsogbu nhazi, ọgụ na-enweghị nchịkwa nke agụụ, ịda mbà n'obi, ọhụhụ, ọhụụ na-adịghị mma, ọrịa dyspeptik. A na-egosipụtakwa mmeghachi omume nke adrenergic: nchekasị, ọsụsọ, ọdịda ọbara mgbali, ọrịa obi na-efe efe, mgbagha obi. Ọrịa diski diski, ọgba aghara na ụsụ nke mbibi, na mmeghachi omume anụ ahụ (rashes, erughị ala, erythema, urticaria, Quincke's edema) bụ ihe njiri mara.
Agaghị enwe ọgwụgwọ na-aga nke ọma n’etinyeghị obere carb nri. N'ihi ihe egwu dị egwu, ndị ọkwọ ụgbọ ala kwesịrị ịkpachara anya jiri ọgwụ ahụ. Otu ndụmọdụ a na-emetụta ndị nnọchite nke ọrụ metụtara ogo mmeghachi omume dị elu na itinye uche.
Ọkpụkpụ nke imeju na akwara na-akpalite ịba ọcha n'anya, mmụba nke ọrụ enzyme.
Ọ bụrụ na onye ahụ mara ihe, ọ kwesịrị ịra swiiti, aụọ otu iko tii ma ọ bụ ihe ọzọ nwere carbohydrates. Mgbe ọnọdụ ahụ gbanwere, endocrinologist chọrọ nyocha iji dozie dose ma ọ bụ dochie ọgwụ.
Analogues nke ọgwụ
Dabere na ngalaba na-arụ ọrụ maka Diabetalong, analog ga-abụ ọgwụ Glidiab kwesịrị ka ru 140 rubles. Ndị dọkịta nyere Diabeton na Diabeton MV ọgwụ dị elu na ọnụahịa dị elu site na 286 ruo 318 rubles. N'ime usoro synonymic, a na-atụ aro Glyclada.
Nkwadebe nke nwere ụdị hypoglycemic mmetụta dịka Amaril, Glimepiride, Glemaz, Glyurenorm ga-abụ nke ọma na ihe mejupụtara. Edere ha maka hypersensitivity ma ọ bụ ihe mgbochi ọzọ maka glycoside.
Mwepụta wepụtara, ọnọdụ nchekwa
A na-emepụta mbadamba mbadambalong nke Synthesis OJSC na MS-Vita LLC na ngwugwu na-acha. A na-etinye blisters n'ime igbe kaadiboodu.
Enwere ike ịchekwa ọgwụ ahụ ruo afọ 3 n'ụlọ okpomọkụ, n'enweghị ike inweta ìhè anyanwụ na ụmụaka. N'ime ụlọ ahịa ọgwụ, Diabetalong dị maka inye ọgwụ iji zụta 98-127 rubles. maka mbadamba 60 nke 30 mg.
Nyocha Diabetalong
Ọria mamiri amụrụla ọrịa Diabetolong, na nyocha na-achọpụta uru ya:
- Mmezi nke ihe eji egosi glucometer;
- Ezi ndakọrịta na ọgwụ ndị ọzọ;
- Ọnụ ọgwụ dị oke ọnụ;
- Ike idalata ibu n’oge ọgwụgwọ.
Ọ bụghị mmadụ niile nwere afọ ojuju na achọrọ njikwa glycemic kwa ụbọchị (ugboro ise kwa ụbọchị), mana ka oge na-aga, ndị na-egosi ya kwụsiri ike ma mkpa njikwa njide onwe ya belatara.
Na mkpokọta, Diabetalong bụ ọgwụ ịgwọ ọrịa antidiabetị ịdabere na ya nke na-edozi profaịlụ glycemic. Mgbe ejiri ya n'ụzọ ziri ezi, ọ na-enwe ike igbochi ihe omume obi na ọrịa ndị ọzọ siri ike nke ụdị shuga 2.
