Protafan - ntuziaka zuru ezu maka ojiji

Ọrịa shuga mellitus na-ezo aka na ọrịa na-adịghị ala ala na-emetụta akụkụ ahụ niile. A na - ejikọta usoro nke mmepe dị na ụkọ insulin nke hormone, nke na - ahụ maka itinye glucose site na mkpụrụ ndụ. N'ihi nke a, enwere nghọtahie na metabolism, ọkwa glucose dị n'ọbara na-ebili. Usoro ọgwụgwọ nke ọrịa shuga mellitus na-agbago ruo mgbe ọ ga-edochi homonụ dị ogologo ndụ.

Azoputala uzo nile siri puta. Otu n’ime ha bụ Protafan. Ntụziaka maka iji ya nwere ozi zuru oke dị mkpa maka iji nnwere onwe nke ọgwụ a dị mkpa.

Ngwakọta na ụdị ntọhapụ

Ihe na-arụ ọrụ bụ insulin mmadụ, nke teknụzụ sitere na mkpụrụ ndụ ihe mepụtara. Dị na ọtụtụ usoro onunu ogwu:

1. "Protafan NM": nke a bụ nkwusioru na vials, kwa 10 ml, insulin concentrated nke 100 IU / ml. Ihe ngwugwu nwere otu karama.
2. "Protafan NM Penfill": katriki nke nwere 3 ml (100 IU / ml) nke ọ bụla. Na otu ọnya - 5 katalọgụ, na ngwugwu - 1 ọnya.

Ndị ọkachamara: mmiri maka injection, glycerin (glycerol), phenol, sodium hydrogen phosphate dihydrate, protamine sulfate, metacresol, sodium hydroxide na / ma ọ bụ hydrochloric acid (iji dozie pH), zinc chloride.

Omume ọgwụ

"Protafan" na-ezo aka ọgwụ ọgwụ hypoglycemic nke obere oge. Ebumnuche bụ ebumnuche bụ ime ka glucose na-abanye n’arụ sel.

Ọzọkwa na-ebido usoro ndị a:

• Ọ na - eme ka ọtụtụ enzymes dị mkpa maka ndụ - glycogen synthetase, pyruvate dehydrogenase, hexokinase;
• Blocks adipose anụ ahụ lipase na lipoprotein lipase;
• Na-akpali phosphorylation nke protein protein.

N'ihi ya, ọbụghị naanị ụzọ glucose n'ime sel na-eme ka ọ dịkwuo mma, kamakwa yana ojiji ya na nguzobe nke glycogen. Ọzọkwa, a na-amalite njikọta nke protein cellular.

Cipleskpụrụ nke iji Protafan

A na-eji ọgwụ ahụ eme ihe maka ụdị ọrịa ọ bụla. N’ime Idị nke mbụ, a na-amalite ya ngwa ngwa, n’ụdị nke II, a na-egosi Protafan n’ọnọdụ arụmọrụ sitere na ụdị ọgwụ sulfonylurea, n’oge afọ ime, n’oge na mgbe ọ rụsịrị ọrụ, n’ihu ọrịa ndị na-agbakọ agbakọ na-agbagha usoro nke ọrịa shuga mellitus.

Ọgwụ mlọ Ọgwụ

A na-edekọ mmalite mmalite nke ihe dị ka awa 1.5 mgbe nchịkwa subcutaneous gasịrị. Arụmọrụ kachasị - mgbe awa 4-12 gasịrị. Mkpokọta oge nke ime ihe bụ awa 24.

A pharmacokinetics na-akọwapụta ụkpụrụ izugbe nke eji "Protafan":

1. Mellitus na-arịa ọrịa shuga na-arịa - dị ka ihe bụ isi maka ya na insulins na-adị mkpụmkpụ.
2. A na-anabata ọrịa shuga na-arịa insulin na-abụghị insulin - ma monotherapy na onye nnọchianya a yana ngwakọta na ọgwụ ndị na-eme ngwa ngwa.

Ọ bụrụ na eji ọgwụ ahụ eme ihe dị ka ọgwụgwọ anụ, ọ bụ ọnụ tupu nri. Na usoro eji arụ ọrụ, a na-ahụ maka otu ugboro n'ụbọchị (n'ụtụtụ ma ọ bụ na mgbede).

Ofzọ nke ngwa

Ọgwụ a na-abanye n’ahụ. Ebe ọdịnala bụ mpaghara hip. A na-anabata ịbanye na mpaghara nke mgbidi akuku ihu, ogwe aka ya, na uru ahụ dị na ogwe aka. Ekwesịrị ịgbanwere saịtị injection iji gbochie mmepe nke lipodystrophy. Ọ dị mkpa ịdọrọ ikiri akpụkpọ ahụ nke ọma iji gbochie insulin nke anụ ahụ na - egbochi insulin.

Ofzọ iji mkpịsị sirinji maka insulin "Protafan"

Ogologo oge iji aka ya mee ihe n ’icho ihe icho ichochu odi nfe. Maka ebumnuche a, etolite mkpịsị mkpụrụ sirinji, nke a na-eji mmanụ ụgbọ ala Protafana eme mmanụ.

Onye ọ bụla na-arịa ọrịa shuga kwesịrị ịma ntuziaka maka ojiji ya site n'obi:

• Tupu ijuputa katriki, lelee nkwakọ ngwaahịa iji jide n'aka na usoro ịse ahụ ziri ezi.
• Gbalịsie ike nyochaa katki ahụ n'onwe ya: ọ bụrụ na ọ nwere ihe ọ bụla mebiri emebi ma ọ bụ oghere dị n'etiti teepu ọcha na pịpị rọba, mgbe ahụ ejighị nkwakọ ngwaahịa a.
• A na-eji akpụkpọ ahụ roba mee ya na ọgwụ na-ehicha ya.
• Tupu ị wụnye kadi ahụ, a na-adọ mmiri pọmpụ. Iji mee nke a, gbanwee ọnọdụ ahụ ka bọọlụ iko ahụ wee banye n'otu nsọtụ gaa na nke ọzọ opekata mpe 20. Mgbe nke a gasị, mmiri mmiri kwesịrị iburu oke gbaa.
• Naanị katalọgụ ndị ahụ nwere opekata mpe insulin iri na abụọ kwesiri ka agwakọta dịka usoro akọwara. Nke a bụ nke kacha nta karịa maka ejupụta n'ime mkpụrụ sirinji.
• Mgbe etinye ya n'okpuru anụ ahụ, agịga ahụ kwesịrị ịnọ ebe ahụ opekata mpe isii. Naanị na nke a, a ga-abanye dose ahụ kpamkpam.
• Mgbe ogwu ogbugba nke ọ bụla, a na-ewepụ agịga ahụ na sirinji. Nke a na - egbochi ịpụ mmiri mmiri na - achịkwaghị achịkwa, na - eduga ngbanwe nke usoro nke fọdụrụ.

Ihe ndị a niile dị n’elu na-egosi ihe ize ndụ nke mgbanwe mgbanwe mkpokọta insulin na ọgwụ ma ọ bụ enweghị ike ya, nke nwere ike ibute enweghị mmetụta na nsonaazụ ahụike na-adịghị mma.

Dose

Onye ọ bụla na-arịa ọrịa shuga nwere usoro ya na usoro nke insulin. A na-agbakọ ya na endocrinologist n'otu n'otu, dabere na ọkwa glucose dị ala na mmepụta nke homonụ nke ya.

Omume akpachapụghị anya banyere dos na ntinye nke dọkịta na-eduga n'ịzụlite nsogbu ndị siri ike na ọgwụgwọ insulin: hypo- or hyperglycemic coma, nke nwere ike ibute ọnwụ onye ọrịa.

Principleskpụrụ dị iche iche maka ịhọrọ ọgwụ nke "Protafan":

1. Ọgwụ kwesịrị inye ọgwụ maka mmiri ọgwụ, nke dị 0.3-1 IU / kg / ụbọchị.
2. Ọnụnọ nke nguzogide insulin chọrọ ịrị elu na mkpa bụ isi, yabụ sọkwa ọgwụ a. A na-ahụ nke a n’oge uto ma ọ bụ n’ebe ndị ọrịa buru ibu.
3. Ọ bụrụ na onye ọrịa ahụ ejigide insulin nke nsị nke insulin, mgbe ahụ, a na-agbanwe ọ̀gwụ ahụ gbadaa.
4. Ọrịa na-adịghị ala ala nke imeju na akụrụ na-ebelata mkpa ahụ insulin nwere.
5. Amara maka usoro ọgwụgwọ ziri ezi bụ ọkwa glucose n'ọbara. Nke a dị mkpa iji nlezianya nyochaa ihe ngosi a oge niile.

Nnabata na nkwenye niile maka iwebata "Protafan" na-eduga na nkwụsi ike nke carbohydrate ma na-ebubata oke nke ọdịdị ahụ.

Mmeghachi omume ọjọọ

Ọtụtụ mmeghachi omume na-adịghị mma mgbe ị ofụ ọgwụ ahụ bụ n'ihi ihe nke insulin na-emebi usoro usoro onunu ogwu. Ihe kachasị dị ize ndụ n'etiti ha bụ ọnọdụ hypoglycemic. Ọ na-ebilite n'ihi iwebata insulin dị otú ahụ nke karịrị mkpa ya.

N’ihi nke a, itinye uche nke glucose na ọbara na-agbadata nke ukwuu, neurons nke ụbụrụ na-amalite inwe ume ike, mmadụ na-atụfu mmụọ. Na enweghị enyemaka mberede, Coma na ọnwụ na etolite.

Mmeghachi omume ndị ọzọ na-adịghị mma ma ọ na-esonyere na mmetụta ọjọọ nke mmiri ọgwụ. Ndị a gụnyere:

• Mmeghachi omume nfụkasị ahụ. Site na obere amị na rashes ruo na nzaghachi sitere na ya: rashes n'ahụ niile, ọzịza nke anụ ahụ, mkpụmkpụ ume, tachycardia, itching siri ike, sweating. N'okwu ndị kachasị sie ike - nkụda mmụọ na enweghị uche.
• Mgbaàmà nke akwara ozi. Ejiri akwara Peripheral neuropathy nwee ụdị mgbaàmà dị iche iche: mmebi nke sistem akwara autonomic, uche na-egbu mgbu na aka na ụkwụ, paresthesia.
• Site n'akụkụ akụkụ ahụ nke ọhụụ. N’oge na-adịghị anya, ajọ njehie na-eme, nke na-apụkarị ma nwa oge. N'oge mmalite ọgwụgwọ, iwere ọrịa shuga na-arịa ọrịa shuga nwere ike ime.
• Akpụkpọ anụ na anụ ahụ dị n'okpuru ala. Site na nchịkwa insulin ogologo oge n'otu ebe, lipodystrophy na-amalite.
• Mmeghachi omume mpaghara Na - eme na mpaghara nchịkwa ọgwụ: ịcha ọbara ọbara, ọzịza nke anụ ahụ, itching, hematoma. Mgbe oge ụfọdụ gasịrị, ha ga-apụ n'anya n'enweghị njigide.

Onye ọ bụla nwere ọrịa shuga kwesịrị ịma usoro algorithm maka inye aka na ọnọdụ hypoglycemic.

Ihe ngbanwe

Amachibidoro "Protafan" iji naanị n'ọnọdụ abụọ: ọnọdụ hypoglycemic na ntachi obi na otu akụkụ nke azịza ahụ.

Mmekọrịta na ọgwụ ndị ọzọ

Ọrịa shuga mellitus bụ ọrịa na-adịghị ala ala nke na-ebutekarị nsogbu site na ọtụtụ akụkụ ahụ. Maka ọgwụgwọ ha, a na-enye onye ọrịa ahụ ọgwụgwọ kwesịrị ekwesị. E nwere ọtụtụ ọgwụ na-emetụta ahụ anụ ahụ insulin chọrọ (bulie ma ọ bụ ibelata ya). Maka ojiji ha jikọtara ya na Protafan, o kwesịrị idozigharị ọgwụ a.

Na-emezi mmetụta nke "Protafan"

• Ngwaahịa niile nwere ethanol. Ndepụta ha buru ibu, yabụ, mgbe ị na-etinye ọgwụ ọhụrụ, ọ dị mkpa iji mụọ ihe mejupụtara ya n'ụzọ zuru ezu;
• Ndị na - egbochi ACE (angiotensin-eningme enzyme) - otu ọgwụ ọgwụ ndị a na - ejikarị na - agwọ ọbara mgbali elu;
• MA inhibitors (monoamine oxidases) - antidepressants ejiri na psychiatry;
• Ndị na - egbochi beta (ndị na - adịghị ahọpụta) - ọgwụgwọ nke ọrịa na akụrụngwa;
• Steeti anabolic;
• Ọgwụ ọgbụgba ọgwụ hypoglycemic;
• Carbonic anhydrase inhibitors, nke gunyere otutu oria;
• Nkwadebe Lithium;
• Ọgwụ mgbochi Tetracycline na sulfonamides;
• Pyridoxine (Vitamin B6);
• Ketoconazole bụ onye na-ahụ maka ọgwụ antimycotic;
• Cyclophosphamide - ọgwụ antitumor;
• Clofibrate - wedata cholesterol ọbara dị ala;
• Fenfluramine bụ onye na-achịkwa agụụ;
• A na - eji Bromocriptine mee ihe na gynecology;
• Theophylline bụ ihe atụ ama ama;
• Mebendazole bụ ọgwụ anthelmintic.

N'ime ndị ọrịa chọrọ ọgwụgwọ na ọgwụ ndị a, ọ dị mkpa iji belata oge nke ọgwụ insulin nwere.

Belata mmetụta nke "Protafan"

• Homonụ thyroid eji maka ọgwụgwọ nnọchi hypothyroidism;
• Ọgwụ mgbochi calcium tubule mgbochi (calcium antagonists), nke a na-ejikarị na ọgwụgwọ nke ọbara mgbali elu;
• Glucocorticosteroids;
• Sympathomimetics, onye ama ama nke Ephedrine;
• Thiazide diuretics;
• Ogwu uke ogwu ibot;
• Ihe ngbochu ogwu;
• Clonidine bụ onye na-ahụ maka hypotensive;
• Phenytoin bụ ọgwụ mgbochi;
• Diazoxide nwere mmetụta diuretic na hypotensive;
• Uto hormone (uto uto);
• Nicotinic acid;
• Morphine;
• Nicotine;
• Heparin;
• Danazole jibu ọgwụgwọ endometriosis na ụfọdụ ọrịa ọnya na-arịa ọrịa gynecology.

Drugsfọdụ ọgwụ na kemịkal na-eme ihe dị iche iche, ma na-akwalite ma na-egbochi mmetụta Protafan. Ndị a bụ mmanya ọkụ, octreotide / lanreotide, reserpine, salicylates.

Ọnọdụ nchekwa

Storagechekwa Protafan nke ọma ga - eme ka nchekwa insulin kwalite ịta ahụ, nke pụtara na ọ ga - egbochi ọtụtụ nsogbu:

1. Kalama mechiri emechi dị na friji (2-8 Celsius C), mana tere aka na friza. A machibidoro kpam kpam ịhapụ ijiji. Okwu ahụ bụ ọnwa iri atọ.
2. A na-echekwa nkwakọ ngwaahịa mepere emebi n'ime ụlọ agaghị akarị 25 Celsius C maka izu isii. Chedo ìhè.

Ekwesịrị ichebe ọgwụ a site na ụmụaka. A di ya na ahia ogwu naanị n’inye ndenye ọgwụ. Ọnụ ego dị 350-400 rubles maka karama, 800-100 rubles maka katọn. Anafọdụ analogues dị ọnụ ala (dịka ọmụmaatụ, Humulin NPH), ndị ọzọ karịrị ya na ọnụ ahịa (Insuman Bazal GT, Biosulin N).

Ntụziaka pụrụ iche

Na ọgwụgwọ ọrịa shuga mellitus "Protafan" enweghị ihe ndị dị obere. Anyị na-edepụta ụfọdụ "ụzọ aghụghọ" nke ndụ onye ọrịa nwere ike ịdabere:

1. Mgbe ịkwụsị ị drugụ ọgwụ ahụ, ọnọdụ nke hyperglycemia nwere ike ime (adịghị ike, ọgbụgbọ, ọnụ na-egbu egbu, agụụ na-egbu, na-akpọ isi acetone, urination ugboro ugboro, ọnya na-acha ọbara ọbara na nkụ na-eji nwayọọ nwayọọ na-abawanye).
2. Ọ bụrụ na n'oge ọgwụgwọ enwere oke nrụgide, ọrịa (ọkachasị ahụ ọkụ) ma ọ bụ mgbatị anụ ahụ dị ukwuu, nke a na-akpalite hypoglycemia.
3. Dochie ọgwụ ahụ n'ụdị insulin ọzọ (ma ọ bụ ọgwụ nke ụdị dị iche) ga-arụ ọrụ n'okpuru nlekọta ahụike yana ilebanye ọkwa ọkwa shuga n'ọbara.
4. Tupu njem dị ogologo na mgbanwe oge mpaghara, onye ọrịa ahụ kwesịrị ịga nyocha endocrinologist.
5. Emebeghi Protafan NM ka ọ banye n'ime mmiri insulin.

Ọgwụ ahụ abanyeghị n’ịkwa akwa, yabụ ụmụ nwanyị dị ime nwere ike iji ya. Ọ dị oke mkpa ịgbanwe nhazi ahụ dabere na oge ịtụrụ ime (na ọkara nke mbụ, mkpa insulin na-agbada, mgbe ahụ jiri nwayọ mụbaa, ma mgbe amuchara nwa, ọ laghachiri n'ụkpụrụ mbụ ya).