A na-eji nkwadebe insulin mee ihe maka iji ọgwụ dochie ndị ọrịa nwere ọrịa shuga. Edebere ha site na oge ime ha to obere na ogologo. Oge ọrụ maka ndị dị iche iche bụ nke ya. Ya mere, nhọrọ nke ọgwụ insulin na-arụkarị n'ụlọ ọgwụ.
Iji mezuo nke a, na-achịkwa ọkwa nke glycemia n'ụbọchị. Mgbe ahụ dọkịta depụtara usoro ọgwụ insulin dị iche iche dabere na ọnụego metabolic, nri, mmega ahụ, ijikọta ụdị ọgwụ dị iche iche.
Ka a na-akwụghachi ụgwọ metabolism karị, ọ na-enwekarị ọ̀tụ̀tụ̀ glucose ọbara kwa ụbọchị, ma, ya mere, belata ihe ize ndụ nke ọrịa shuga.
Iwu dị mkpa maka ọgwụgwọ insulin
Dị ka ọ na-adịkarị, a na-emepụta 23-59 IU nke insulin, nke a bụ ihe dị ka 1 n'arọ nke anụ ahụ - 0.6 - 1.0 IU. A na - ekewa secretion a na basal na nri (bolus). Ihe nzuzo insulin na-adi ihe ruru 1 nkeji kwa elekere. Nri kpaliri, imepụta na mwepụta nke insulin - 1 otu maka carbohydrates ọ bụla 10 ma ọ bụ 12 g (1XE).
Mkpa insulin dị ukwuu n'ụtụtụ, ọ na-enwekwu uche na mgbede. Nke a dị mkpa maka ịhazi usoro nchịkwa ọgwụ, ebe ebumnuche nke ọgwụ insulin bụ ime ka nhazi insulin nke usoro iche iche nke nzuzo ha.
A na-akpọ usoro a ntọala-bolus ụkpụrụ nke nchịkwa insulin. Ọ na-eme ka ọgwụ insulin sie ike na ojiji nke ndị na-ewepụta insulin. Kpoo nzuzo nke insulin n’usoro, belụsọ maka carbohydrates (glucose), amino acids na protein.
Insulin eweputara nwere uzo ozo di iche iche, nke ozo dabere na ihe ndi a:
Kacha mkpa n’ime ndị a:
- Okpomoku nke ikwado insulin, ike ya.
- Olu nke nnu inpa.
- Oria ogwu (ngwa ngwa site n’ahu akpukpo ukwu di nwayọ, nwayọ site n’apata ma obu ubu).
- Mmega ahụ.
- Ọnọdụ Sistemu na-enwe Ọrịa
Ebumnuche nke ọgwụgwọ insulin: Vozulim N, ihe ngosi
Edebere insulin iji mee ka metabolism metabolism dị ọcha. Nke dabara na, nke a pụtara inweta glucose ọbara na-ebu ọnụ, na-ezere mmụba dị ukwuu mgbe ị risịrị nri, ekwesighi inwe glucose na mmamịrị, enweghị mwakpo hypoglycemia.
Ndị na-egosi afọ ojuju nke ịgwọ ọrịa bụ Mbelata ma ọ bụ iwepụ isi ihe kpatara ọrịa shuga, enweghị ketoacidosis, hyperglycemia siri ike, ọgụ ugboro ugboro nke hypoglycemia.
Withgwọ insulin na-enye gị ohere ịha ahụ nkịtị nke ndị ọrịa ma rie nri nwere carbohydrates (ewezuga nke ndị dị mfe), jigide mkpokọta protein, protein cholesterol.
Ebumnuche kasịnụ nke ọgwụ insulin bụ ndụ nkịtị, ikike ijikwa ndị na-elekọta mmadụ. Oge nchịkwa insulin n'oge kwesịrị ekwesị na-enyere aka igbochi ma ọ bụ belata nsogbu akwara na akwara.
Isi ihe na - egosi maka ideputa ọgwụ nwere insulin maka ọrịa shuga bụ:
- Firstdị shuga mbụ.
- Ketoacidosis (ịdị iche na ogo).
- Coma: hyperosmolar, ketoacidotic, lactic acidosis.
- Ọrịa nke ogo ogo na nnukwu purulent Filiks.
- Erkwara nta
- Ibelata mfu mberede.
- Ntighari azu akwara, pancreatectomy, necrosis.
A na - eji insulin eme ihe n'agbanyeghị ụdị ọrịa shuga n'ihu microangiopathies siri ike na ọrụ akụkụ ahụ, oke mgbasa ọbara na - emetụta ụbụrụ na myocardial infarction, ịwa ahụ.
N'ime ụdị ọrịa shuga abụọ nke ọrịa mellitus, a na-egosikwa insulin maka iguzogide ọgwụ a na-a oụ a andụ na nnukwu hypertriglyceridemia, a na-eji ya mee ihe banyere ọrịa shuga na-enweghị afọ ojuju.
Etu esi abanye Vulim N?
Ọgwụ bụ insulin mmadụ, isofan, nke enwetara site na inyocha mkpụrụ ndụ ihe nketa. Sdị usoro onunu ogwu bụ nkwusioru maka nlekọta n'okpuru anụahụ. Otu mililita nwere inspee 100 nke insulin. Odikwa na 10 mil vials na katrized na olu nke 3 ml.
Iji banye Vozulim N, ịkwesịrị ịma otu esi etinye insulin n'ụzọ ziri ezi. Tupu okwu mmeghe, ịkwesịrị ị theụ karama ahụ na friji n'ime nkeji iri atọ. Lelee ụbọchị mwepụta na ụbọchị mmebi. Ọgwụ mebiri emebi ma ọ bụ meghee ọgwụ karịa ụbọchị 28 gara aga, enweghị ike ịnye ya.
Ekwesịrị ịsa ya naanị ma ọ bụ sachaa aka ya na akpụkpọ dị ọcha (ekwesịghị ịkpụ mmanya). Ekwesịrị ịgagharị karama insulinul Vozulim N aka ya ka agba nke nkwusioru ya gh o ocha, urukpuru.
Ọ bụrụ na ejiri sirinye jiri ọgwụ ntụtụ ahụ, a ga-ahụrịrị iwu ndị a:
- Ejila ihu ọ bụla dị n'elu agịga.
- Jiri nlezianya lelee dose nke insulin.
- Ebe ntanetị ahụ ekwesịghị ịdị nso na ntụpọ ojii n'ahụ (dị nso karịa 2.5 cm) ma ọ bụ otube;
- Mgbe ịgba ntụtụ ahụ, sirinji ahụ kwesịrị ịdị n'okpuru akpụkpọ ahụ maka sekọnd 5 ọzọ.
- Ekwesịrị iji kpochapụ agịga ahụ na sirinji ka ejiri ọgwụ ahụ.
Mgbe ị na-eji mkpịsị sirinji na-akpọ ọgwụ ahụ, ịkwesịrị ịtọ onye nkesa ahụ na ọkwa ịchọrọ wee pịa bọtịnụ mmalite. Mgbe nke ahụ gasị, jide mkpịsị akwụkwọ ahụ maka sekọnd iri n'enwepụghị ya na akpụkpọ ahụ. A ga-atụfu agịga ejiri.
A ga-agbanwerịrị ebe a na-agba agba mgbochị, na-eme atụmatụ onwe gị. Iji belata nro, ịchọrọ inwe agịga dị warara ma dị mkpụmkpụ.
Kedu ka Vulim N si eme ihe mgbe nchịkwa gasịrị?
Vozulim N bụ insulin nke na - agbanwe ike mmadụ. Iji bido iwetulata shuga dị ala, ọ ga-ejikọ otu onye na-anabata ihe n'ụsọ akpụkpọ ahụ. Vozulim N mepụtara insulin + receptor complex nke na-akpali mmeghachi nke biochemical intracellular.
Mbelata nke glycemia nwere njikọ na ịba ụba nke glucose site na mkpụrụ ndụ yana ntinye ya na usoro metabolic nke glycolysis maka ike. Insulin nwekwara ikike iji mee ka okpukpo oku na glycogen me ngwa. N'ime mkpụrụ ndụ akwara, mgbochi nke ụmụ irighiri glucose ọhụụ na mmebi nke ụlọ ahịa glycogen ka egbochi.
Oge ihe insulin Vozulima N mere bụ n'ihi ọnụego mmiri. Ọ dabere na ọtụtụ ihe: dose, usoro, ebe nchịkwa. N'akụkụ a, profaịlụ nke insulin na-arụ ọrụ metụtara mgbanwe na ma ndị ọrịa dị iche iche na otu onye.
Mmetụta ọgwụ ahụ na-amalite 1 awa mgbe nchịkwa, mmetụta kachasị (ọnụ ọgụgụ kachasị elu) dị n'agbata awa 2 na 7, oge ọrụ nke Vozulima N bụ awa 18-20. Emebiwo site na insulinase n'ime imeju. Ọ na-apịpụta akụrụ.
Atụmatụ eji Vozulima N:
- Enwere ike inye ya ndi nwanyi di ime na oge inye ara.
- A na-eme ntụtụ ahụ n'okpuru anụ ahụ, ihe ngwọta kwesịrị ịdị na nrị ahụ ụlọ.
- Nchịkwa nwere ike ime n'otu oge insulin mkpụmkpụ - Vozulim R.
- Jiri kateeti maka mkpịsị sirinji.
- N'ihi na enwere ike ịda otu akụkụ, anaghị atụ aro iji insulin nfuli.
Ọ bụrụ na edepụtara insulin n'oge izizi ma ọ bụ mgbanwe ya mere, nwee nnukwu nrụgide anụ ahụ ma ọ bụ nke uche, mgbe ahụ, belata ikike ịkwọ ụgbọala nwere ike. Ijikwa usoro na-aghọ ọrụ dị ize ndụ.
Ya mere, ha anaghị akwado ọrụ chọrọ nlebara anya, ngwa ngwa nke uche na moto.
Nsonaazụ na nsonazụ
Nlekọta nke insulin na-edugakarị na mbelata shuga ọbara. Obi ndị ọrịa nwere ọrịa shuga anaghị egosipụta ya mgbe niile gbasara ọnọdụ ụlọ ọgwụ. Na neuropathy na-arịa ọrịa mamịrị, enwere ike ghara ịchọpụta mbelata ọbara dị ukwuu, na ọrịa shuga na-agbasa, ọbụna ntakịrị ntakịrị na glycemia na-akpata ahụ erughị ala.
Mgbaàmà nke mwakpo hypoglycemic metụtara ọrụ nke usoro enweghị ọmịiko na mbelata inye nri n'ụbụrụ. Ọsụsọ, agụụ, aka na-ama jijiji, nchekasị dị n'ime, ọnụọgụ egbugbere ọnụ na ire, adịghị ike pụtara.
Ihe ngosi nke hypoglycemia na-eme n'ihi na ụbụrụ enweghị ụlọ nchekwa glucose nke ya, ma mgbe wedata nri ahụ, ọ na-emeghachi omume hypoxia na ọgbụgba, adịghị ike, na nri nri. Mgbe ahụ, a na-agbanye mkpịsị akwara na pituitary gland, a na-ahapụ homonụ. A malitere usoro nke mmeghachi omume homonụ iji weghachi ọrịa glycemia.
Iji gwọọ hypoglycemia na mbido mbụ na ogo dị nro, o zuru iji were shuga, mmanụ a ,ụ, swiiti, mbadamba glucose. N'ọnọdụ dị njọ na mmụọ nwere nsogbu, a ga-akpọga ndị ọrịa n'ụlọ ọgwụ ebe a na-enye glucose ọbara n'ọtụtụ ọbara ma gbanye glucagon.
Udiri hypoglycemia ugboro ugboro na ọrịa shuga mellitus na-eduga na mmepe nke insulin overdose syndrome (Somoji syndrome). Ihe omuma ya banyere ya bu ndi a.
- Nnukwu mkpa maka insulin (nguzogide insulin na-agha ụgha).
- Lazọ ọrịa shuga (pseudolability).
- Igha ibu ma ọ bụ oke ibu nwere nnukwu glycosuria.
- Ime ka metabolism dị n’ime ala ka ọ dị n’eriri ọrịa na-abaghị uru ma ọ bụ doses dị ala.
- Achọla ịdị mma nke ịba ụba.
- Obi agụụ na-agụkarị ya.
- Nnukwu mgbanwe na glucose ọbara na mmamịrị.
Nguzogide ọgwụ insulin nwere ike ịmalite, ọbụlagodi nkeji iri asatọ anaghị ebute nsonaazụ achọrọ, a na-ahụkwa ọgwụ mgbochi ọgwụ insulin n'ime ọbara. Nlegide insulin bu nwa oge (ya bu oria, oria, iwepu oria ma obu nke oria endocrine) ma di ogologo.
A na-egosipụta mmeghachi omume Allergic n'ozuzu na insulin n'ụdị edere Quincke ma ọ bụ urticaria juputara, ha dị ụkọ. Ejiri mmeghachi omume mpaghara na-egosi ọdịdị hyperemia, ọzịza na ntụtụ ebe insulin ma ọ bụ itching akpụkpọ. A na-ahụkarị, ngosipụta mpaghara anaghị achọ ọgwụgwọ ma na-apụ n'anya n'enweghị nsonaazụ ya.
Lipodystrophy dị na ntanetị nke inulin, yana usoro atrophic na anụ ahụ subcutaneous, mgbe a na-abanye insulin mmadụ, ọ bụ mmebi nke nchịkwa insulin, yana mmeghachi omume mgbochi ọrịa na ndị ọrịa maara banyere nhazi insulin. Maka mgbochi, ịkwesịrị ịgbanwe ebe ntụtụ.
Ná mmalite nke ọgwụgwọ insulin ma ọ bụ na-abawanye na usoro nchịkwa, insulin edema na-etolite, nke na-apụ n'anya na-ejighị ọgwụ mgbatị ọnwa. Ejikọtara nke a na mmepe mmeghachi omume immunological na njigide sodium n'ahụ.
Ededị edema ahụ nwere ike ịpụta na nkwarụ anya nke na-adịghị ala ala na mmalite nke iji nkwadebe insulin. Oghere ahụ na-agbanwe ike ya na ndị ọrịa na-enwe ọhụhụ na-adị nwa oge na agụ ọgụgụ. Njirimara a nwere ike inogide site na otutu izu ma ochoghi ọgwụgwọ ma obu iko nke ndozi
Vidio dị n’isiokwu a na-egosi usoro eji edozi insulin.
