Taa na Russia ihe karịrị nde 10 nke ndị nwere ọrịa shuga ka edere aha. Ọrịa dị otua na - ebulite ntule insulin tinyere aka na usoro metabolic.
Nye ọtụtụ ndị ọrịa, a na-egosi insulin kwa ụbọchị maka ndụ zuru oke. Agbanyeghị, taa na ahịa ọgwụike emeghị 90% nke insulin insulin na Russian Federation. N'ihi gịnị ka ihe a ji na-eme, n'ihi na ahịa insulin na-erite uru na nkwanye ùgwù dị ukwuu
Taa, nrụpụta insulin na Russia n'ụzọ anụ ahụ bụ 3.5%, yana na ego - 2%. A na - eme atụmatụ ahịa insulin niile na nde dollar 450-500. N'ime ego a, nde 200 bụ insulin, ma zụrụ nke ọzọ na nyocha (ihe dị ka nde 100) na mbadamba hypoglycemic (nde 130).
Ndị na-emepụta insulin n'ime ụlọ
Kemgbe 2003, Medsintez na-arụ ọrụ insulin malitere ịrụ ọrụ na Novouralsk, bụ nke na-emepụta ihe dị ka 70% nke insulin akpọrọ Rosinsulin.
Mmepụta na-ewere ọnọdụ n'ime ụlọ 4000 m2, nke nwere ụlọ ọcha 386 m2. Ọzọkwa, osisi ahụ nwere ebe nchekwa klaasị ịdị ọcha D, C, B na A.
Onye rụpụtara na-eji teknụzụ ọgbara ọhụrụ na akụrụngwa kachasị ọhụrụ nke ụlọ ọrụ azụmaahịa ama ama. Nke a bụ asụsụ Japanese (EISAI) German (BOSCH, SUDMO) na akụrụngwa Italiantali.
Ruo 2012, a na-enweta ọgwụ ndị dị mkpa maka mmepụta insulin ná mba ọzọ. Mana n’oge na-adịbeghị anya, Medsintez mepụtara ụdị nje nke ya ma wepụta ọgwụ ya a na-akpọ Rosinsulin.
A na-eme nkwụchi ụgwọ n'ime karama na katọn nke ụdị atọ:
- P - ihe omumu ihe omumu nke mmadu. Irè mgbe nkeji 30 gachara. mgbe nchịkwa gasịrị, ọnụ ọgụgụ kachasị arụmọrụ na-apụta awa 2-4 mgbe ịgba ntụtụ ahụ wee ruo awa 8.
- C - insulin-isophan, nke ezubere maka nchịkwa sc. Mmetụta hypoglycemic na-apụta mgbe awa 1-2 gasịrị, a na-abanyekarị uche kachasị mgbe awa 6-12 gachara, oge nke mmetụta ahụ na-adịgide ruo awa 24.
- M - Rosinsulin mmadụ abuo maka sc አስተዳደር. Mmetụta ịdalata shuga na-apụta mgbe minit 30 gasịrị, ọnụ ọgụgụ kachasị elu na-apụta na awa 4-12 wee dịruru ruo awa 24.
Na mgbakwunye n'ụdị usoro ọgwụgwọ ndị a, Medsintez na-ewepụta ụdị mkpụrụ osisi mkpụrụ osisi Rosinsulin sirinji abụọ - nke edoziri ma jighachi ya. Ha nwere usoro pụrụ iche e mepụtara maka ha nke ga-enyere gị aka iweghachi usoro ị na-emebu ma ọ bụrụ na edobeghi ya otu ọ kwesiri.
Rosinsulin nwere ọtụtụ nyocha n'etiti ndị ọrịa na ndị dọkịta. A na-eji ya ma ọ bụrụ na enwere ụdị ọrịa shuga 1, ọrịa ketoacidosis, coma ma ọ bụ ọrịa shuga. Patientsfọdụ ndị ọrịa na-ekwu na mgbe nkwalite ya gasịrị, jumps shuga dị n'ọbara na-eme, ndị ọrịa shuga ndị ọzọ, n'ụzọ megidere ọgwụ a, na-ekwe nkwa na ọ ga-enye gị ohere ịchịkwa glycemia kpamkpam.
Ọzọkwa, kemgbe afọ 2011, e mepụtara ụlọ ọrụ na-emepụta insulin mbụ na Oryol Region, nke na-ebu okirikiri zuru oke, na-emepụta mkpịsị mkpụrụ sirinji juputara na nkwusioru. Ndi ulo oru mba uwa bu Sanofi mebere atumatu a.
Agbanyeghị, osisi ahụ anaghị emepụta ihe ndị ahụ n’onwe ha. N'ụdị akpọnwụ, a na-azụta ihe ahụ na Germany, mgbe nke a mechara homonụ nke mmadụ, a na-agwakọta ihe analogues na ihe inyeaka iji nwetaghachi ọgwụ mgbochi. Ya mere, emeputa insulin nke Russian na Orel, mgbe a na-emepụta insulin nke ngwa ngwa na ogologo oge, ụdị nke na-emezu ihe niile achọrọ nke ngalaba German.
WHO na-atụ aro na mba ndị nwere ihe karịrị nde mmadụ 50 ịhazi mmepụta nke homonụ nke ha. Nke a ga - enyere ndị ọrịa mamịrị enweghị nsogbu ịzụrụ insulin aka.
Na mgbakwunye, a na-emepụta insulin site na Geropharm, onye ndu na mmepe nke ọgwụ eji eme ka mkpụrụ ndụ ihe nketa na Russia. E kwuwerị, ọ bụ naanị onye na-emepụta ihe a na-emepụta ngwaahịa ụlọ n'ụdị ọgwụ na ihe.
Ọgwụ ndị a maara onye ọ bụla nwere ọrịa shuga. Ndị a gụnyere Rinsulin NPH (mmetụta etiti) na Rinsulin P (obere ihe). Emere nnyocha emere iji nyochaa ịdị irè nke ọgwụ ndị a, n'oge a hụrụ obere ọdịiche dị n'etiti iji insulin n'ụlọ na ọgwụ ndị mba ọzọ.
Ya mere, ndị ọrịa mamịrị nwere ike ịtụkwasị insulin Russia na-echeghị gbasara ahụike ha.
Ọgwụ ndị ala ọzọ enwere ike dochie insulin n'ụlọ?
Emejuputara usoro ogwu nke ihe omumu nke nkpuru osisi ji aru oru mebere oru nke ulo oru ihe omumu Russia nke bioorganic Chemistry, Russian Academy of Sciences na Obolensk. Mana nke a bụ obere nrụpụta ike, na mgbakwunye, ngwaahịa ahụ na-akwakọba ya na arịa ndị na-adịghị mma maka adabara ụlọ. Ọzọkwa, ụlọ ọrụ ahụ anaghị emepụta ọgwụ nwere mmetụta na-adịgide adịgide.
Banyere Medsintez na Pharmastandart, ndị a na-emepụta insulin na-akwakọ ngwaahịa dị na ha. Ọnụahịa ha fọrọ nke nta ka ọ bụrụ ọnụahịa nke ngwaahịa mba ọzọ.
Agbanyeghị, taa, ụfọdụ ụlọ ọrụ ọgwụ Russia dị njikere itinye aka na mmezu insulin zuru oke. A na-emekwa atụmatụ iwu osisi na mpaghara Moscow, ebe a ga-emepụta ọgwụ ndị dị elu na ọgwụ ọgbara ọhụrụ nke ga-agwọ ọrịa shuga n'ụzọ dị irè. Yabụ, maka otu afọ onye nrụpụta ga-emepụta ihe ruru 250 n'arọ nke ihe.
A na-eche na imepụta insulin nke mmepụta anyị ga-abụ na 2017. Nke a ga - eme ka ndị na - arịa ọrịa shuga zụta insulin nke Russia. Enwere uru ndị ọzọ nke ịmalite ọgwụ ụlọ:
- Nke mbu, osisi ogwu gha ebido meputa homonụ nke ihe ogologo.
- N'ime afọ iri anọ na atọ na-esote, ana-ezube iwepụta akara zuru oke nke ọnọdụ anọ niile.
- Homonụ ahụ ga - adị n'ụdị dị iche iche - enwere ike ịgagharị sirinji, pensụl, karama na katridges.
Mana usoro dị otú a dị ogologo. Ya mere, insulin na Russia agaghị enwe ike dochie ọgwụ mbubata.
Ka ọ dị ugbu a, Novo Nordisk (43.4%), Eli Lilly (27.6%) na Sanofi-Aventis (17.8%) na-abụ ndị isi ụlọ ọrụ n'ahịa ụwa na Russia.
Pharmstandard nọ ọnọdụ nke anọ na ndepụta a (6%), ebe ndị nrụpụta ndị ọzọ na-ejide naanị 3% nke mmepụta insulin na Russia.
Mbupụ insulin Russia na Europe
Kemgbe 2016, ụlọ ọrụ Sanofi (France) nwere ohere iji zipu ọgwụ mgbochi Russia na Germany. A na-arụpụta insulin n'ime mpaghara Oryol na mpaghara Sanofi-Aventis Vostok.
Ọ dị mma ịmara na akụkụ nke atọ nke ahịa insulin (18.7%) bụ ihe onwunwe nke Sanofi Russia. N'otu oge ahụ, onye isi otu ahụ, Victoria Yeremina, na-ekwu na ndị ọrịa mamịrị bi na Russia enweghị ihe ọ bụla ga-echegbu onwe ha, n'ihi na ntinye aka na ahịa Russia ụlọ ga-ebelata n'agbanyeghị agbanyeghị insulin na-ebuga na Europe.
Nke a ga - ekwe omume n'ihi mmụba dị ukwuu nke nrụpụta. N'ezie, ụlọ ọrụ Sanofi Oryol nwere akụrụngwa kachasị ọhụrụ na teknụzụ mmepụta ọfụma. N'ihi ya, akara insulin Glargin Lantus nke Sanofi na-ebute ọnọdụ dị na ire insulin n'ahịa Russia.
Yabụ, insulin ga-abụ ihe mbụ nke ngwaahịa Russia ndị Sanofi na-ebupụ. Maka ụlọ ọrụ French, ụdị edozi ahụ bụ ihe ezi uche dị na ya na uru akụ na ụba, ebe ọ bụ na tupu nsogbu ahụ, ọnụahịa nke mmepụta ọgwụ na Europe na Russia fọrọ nke nta ka ọ bụrụ otu, mana mgbe nke ahụ gasịrị, mmepụta insulin ghọrọ 10-15% dị ọnụ ala. Nwee oke mpịpụta mmepụta ga-ebelata oke nrụpụta.
Vidio dị n'isiokwu a na-ekwu banyere mmepụta insulin na Russia.