Langerin bụ otu n’ime ọtụtụ ọgwụ ọgwụ eji eme ọgwụgwọ maka usoro a na-akpọ ọrịa mellitus na-abụghị insulin. Ọgwụ bụ akụkụ nke ìgwè ọgwụ dị na biguanide, ihe bụ isi ebumnuche ya bụ iji belata mkpa maka imepụta insulin.
Ọnụahịa nke Langerin dị na ụlọ ahịa ọgwụ, dabere na usoro ịchọrọ, nwere ike ịdị site na otu narị ruo narị atọ rubles.
Langerin bụ ọgwụ mbadamba ọgwụ nke a na-eji eme ihe n’ọrịa dị mgbagwoju anya nke ọrịa shuga. Akụkụ bụ isi ya bụ metformin umi. Ọgwụ bụ otu n'ime ọgwụ ndị na-ebelata shuga, a na-ejikarịkwa ya eme ihe iji mee ka ọ̀tụ̀tụ̀ shuga dị n'ọbara dị na ndị ọrịa mamịrị.
Otu n'ime ọgwụ ndị dị otú ahụ ga-ekwe omume bụ nchịkwa ya ma ọ bụrụ na enweghi ike nke mbadamba ọrụ ndị mbụ ejirila na usoro sulfonylurea. Na mgbakwunye, oke ibu bụ nsogbu concoitant maka mmadụ niile nwere ọrịa shuga.
Ọ bụ ya mere, Langerin na-enye ohere ọ bụghị naanị iwetulata shuga dị ala, kamakwa na-enye aka na ịdị nwayọ n'ịdị arọ nke onye ọrịa.
Ngwongwo ọgwụ na ihe ngosi maka ojiji
Usoro ihe omume nke akụkụ ahụ dị mkpa nke ọgwụ ahụ jikọtara ya na ikike ya ịkwụsị mmechi nke gluconeogenesis, yana usoro njikọta nke abụba n'efu na oxidation abụba n'efu. Onye na-anọchite klas biguanide emetụtaghị insulin ewepụtara n'ime ọbara, kama ọ na-agbanwe ọgwụ ọgwụ ya site na ibelata ogo insulin na-ejedebe na ịba ụba nke insulin na proinsulin.
Isi ihe dị mkpa na usoro nke mbadamba ihe ndị dị otú a bụ mkpali nke glucose na-eme n’ihu site na mkpụrụ ndụ akwara.
Isi ihe na-egosi maka iji ọgwụ bụ mmepe nke ọrịa shuga na-akpata insulin na mmadụ, ọkachasị enweghị ike nke nri sochiri.
Njirimara ọgwụ ọgwụ dị na Langerin gụnyere:
- na -ewelata ego nke gemoclobinꓼ glycated
- na - egbochi insulin na - egbochi ọgwụ sel n’ime mmiri ọgwụ insulinꓼ
- ọfụma na - emetụta oke iwu profaịlụ akwara nke plasmaꓼ ọbara
- belata cholesterolꓼ nke ojoo
Na mgbakwunye, iji ọgwụ ahụ eme ihe nwere ike ịbelata oke ahụ.
Ntuziaka maka mbadamba mbadamba
Ọgwụ Langerin dị n'ụdị mbadamba mkpuchi.
Mbadamba mbadamba ndị ahụ na akpa plastic, nke etinyere ya na iji ya mee ya.
A na-etinye akwa n'ime igbe kaadi na ntuziaka maka iji ọgwụ a.
Dabere na usoro achọrọ ọgwụ a na-eji mee ihe, a pụrụ iji ọgwụ were zụta ọgwụ a:
- 500 milligrams.
- Milligrams 850.
- Otu gram nke ihe na-arụ ọrụ.
Ofzọ isi were mbadamba nkume ahụ bụ nke ọnụ, n'oge nri ma ọ bụ mgbe ọ gachara. Dọkịta na-aga ya depụtara usoro ịgwọ ọrịa maka onye ọrịa ọ bụla n'otu n'otu dabere ogo ọrịa ahụ. Ọzọkwa, ọkachamara n’ihe banyere ọgwụ na-ekpebi ọnụọgụ ọgwụ ole n’otu ọgwụ n’ụbọchị.
Ntụziaka Langerin maka iji mee ihe na-atụ aro ịmalite usoro ọgwụgwọ ọgwụgwọ site na iji obere nke 500 mg nke ọgwụ na-arụ ọrụ. Ọnụ ọgụgụ nke ọgwụ mgbe ụbọchị nwere ike ịbụ otu ruo atọ. Nke nta nke nta, enwere ike ịbawanye usoro onunu ogwu rue 850 mg nke ihe na - arụ ọrụ ụbọchị dum (otu ugboro ugboro abụọ n'ụbọchị). Dọkịta na-aga ahụ na-enyocha ọnọdụ onye ọrịa ma ọ bụghị ihe karịrị otu ugboro n'izu, na-edozigharị ọnụọgụ ọgwụ agbagoro elu.
Edekwara ọgwụ a maka ịgwọ ọrịa ahụ na ụmụaka okenye karịa afọ iri. Monotherapy kwesịrị ịmalite site na iji usoro ọgwụ nke 500mg nke ihe na-arụ ọrụ otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị. Mgbe oge ụfọdụ gasịrị, a na-ekwe ka mmụba nke ọgwụ ahụ nwayọ nwayọ, ma ọ dịghị karịa gram abụọ kwa ụbọchị, kewara abụọ ma ọ bụ atọ.
Dị ka ọ na-adị, mgbanwe n’usoro nke ọgwụ a na-apụta mgbe ụbọchị iri ruo ụbọchị iri na ise dabere na nsonaazụ nyocha ọbara maka ọkwa glucose.
N'ọnọdụ ụfọdụ, nkwadebe mbadamba ụrọ bụ akụkụ nke ọgwụ ngwakọta na inje insulin.
Okwesiri iburu n'uche na ochichi nke oge a nke Langerin nwere insulin, ihe ndi ozo nke sulfonylurea, acarbose, ma obu ACE inhibitors na-abawanye hypoglycemic mmetụta nke ọgwụ.
N'ọnọdụ ụfọdụ, dibịa na-aga ahụ nwere ike iji mbadamba ihe mebere ụdị dochie iji Langerin. Taa, enwere ọtụtụ ọgwụ, ihe bụ isi ọrụ ya bụ metformin.
Ọnụahịa ọgwụ analog nwere ike ịdị iche iche, dabere na ụlọ ọrụ ndị na-emepụta ọgwụ.
Kedu ihe bụ contraindications maka ojiji?
Usoro ọgwụgwọ ahọpụtara n'ụzọ na-ezighi ezi ma ọ bụ na-agbasoghị ndụmọdụ nke dibịa na-aga nwere ike ịkpasu ọdịdị nke mmeghachi omume ọjọọ mgbe ị na-a theụ ọgwụ ahụ.
Na mgbakwunye, enwere oge enwere iji iwu ọgwụ megide metformin amachibidoro.
Ntuziaka maka iji ọgwụ ahụ na-egosi ndepụta nke contraindications bụ isi.
Ihe ndi ozo banyere ihe eji eme ihe bu oria Langerin gunyere ihe ndia:
- oke nrụrụ imeju ma ọ bụ ọrụ akụrụ, ọdịda ha
- ahoụrụma, gụnyere n'ụdị na-adịghị ala ala
- obi ma ọ bụ iku ume ọdịda
- nnukwu myocardial infarctionꓼ
- Ọnọdụ akpịrị na-arịa ọrịa shuga ma ọ bụ nna nna
- mmepe nke ọrịa mamịrị ụkwụ na-arịa ọrịa shuga
- na ọnụnọ nke nnabata nke metformin na mmepe nke mmeghachi ahụ nfụkasị ahụ
- ọnụnọ nke ọrịa na-efe efeꓼ
- na-ebu ọnụ na-arịa ọrịa shuga ma ọ bụ na-eso nri nke nri ya kwa ụbọchị anaghị aga otu puku kilocaloriesꓼ
- tupu ịwa ahụꓼ
- ya na mmerụ ahụ buru ibu na nso nso a
- tupu na mgbe nyocha nke na-eji redioaktiiki isotropes nke ayodiin
- ketoacidosis na lactic acidosis.
Na mgbakwunye, ụmụ nwanyị ekwesịghị ị theụ ọgwụ ahụ n'oge ime na lact.
Ihe omume na - ebute nsonaazụ nwere ike igosipụta onwe ya n'akụkụ akụkụ dị iche iche na sistemụ nke ahụ mmadụ - eriri afọ, metabolism, usoro akwara obi, yana akpụkpọ ahụ. Ihe mmeghachi omume kachasị njọ nke nwere ike ịme n'ihi ị theụ ọgwụ bụ:
- Egwuregwu dị elu. Mgbe ụfọdụ ọgbụgbọ na-apụta n'ụdị ọrịa shuga 2. Enwere ike dochie ọgbụgbọ site na ọgbụgbọ.
- Typedị afọ na-egbu mgbu.
- Ntughari nke ihe otite n’ime onu.
- Hematopoiesis na hemostasis.
- Megaloblastic anaemia.
- Mbelata shuga dị n'ọbara n'okpuru ọkwa a nabatara - hypoglycemia.
- Ọdịdị nke adịghị ike n’anụ ahụ.
- Rowsjọ.
- Hypotension.
- Ọrịa akụkụ iku ume.
- Ọdịdị nke dermatitis ma ọ bụ ihe ọkụ ọkụ na anụahụ.
Ekwesịrị ịkpachara anya mgbe ị na-ewere Langerin na ọgwụ ndị ọzọ. Otu mbadamba osisi na cymeditine n’otu oge na-ebulite ohere nke lactic acidosis. Nchikota nke Langerin na akwara loop, nwere ike ime otu ihe ahu. N'okwu a, na mgbakwunye na enwere ike igosipụta lactic acidosis, enwere ike ịhụ ngosipụta nke ọdịda akụrụ.
N'iji ọgwụ ọjọọ eme ihe, ọ dị mkpa iji nyochaa arụmọrụ akụrụ dị mma ma chọpụta ego nke lactate na plasma ọbụlagodi ugboro abụọ n'afọ.
Enyere ozi banyere ọgwụ ndị e ji agwọ ọrịa shuga na vidiyo dị n'isiokwu a.
