Nchoputa nke ihe anakpo pancreatic atrophy putara na olu nke aru di n’ime ala agbadatala, nke emere site na exocrine (enzymes diges) na intracecretory (emeputa insulin na glucagon) enweghi oru nke oru.
N'ọtụtụ eserese, pathogenesis bụ n'ụdị na-adịghị ala ala nke pancreatitis, ọrịa shuga mellitus, somatic pathologies nwere oke ike ọgwụgwụ, ọrịa cirrhosis, na nkwarụ mgbasa. Mgbe ụfọdụ ihe na-akpata ya bụ akpụ.
Iji mee nyocha ziri ezi, a na-eme nchọpụta ọdịiche. Buru n'uche ihe nyocha ụlọ nyocha na-egosi enweghị ụkọ nri nri na obere insulin.
A na-enyocha nyocha nke ultrasound, nke na-egosi mbelata ọnya afọ, mgbanwe mgbanwe na parenchyma. Usoro ọgwụgwọ a gụnyere na nhọpụta ọgwụgwọ nnọchi. Ha na-akwado ọgwụ enzyme, insulin, ọgwụ iji weghachi microflora eriri afọ.
Pathogenesis nke mgbanwe atrophic na pancreas
Mgbanwe atrophic na pancreas bụ physioloji mgbe ha tolitere n’ihi usoro ebumpụta ụwa nke ịka nká. Ha na-arịa ọrịa ọjọọ na-agwụ ike.
Na mgbakwunye, atrophy bụ nsonaazụ nke ụdị ọ bụla nke pancreatitis na-adịghị ala ala, yana akụkụ dị ukwuu nke stroma 
A na-edochi ya na anụ ahụ fibrous, nke na-eduga n'ịbawanye ụba nke endocrine na ụkọ nke exocrine.
Dị ka ọ na-adịkarị, ịdị arọ nke anụ ahụ dị iche site na 80 ruo 90 g. Ọ bụrụ na a hụrụ mgbanwe ndị na-adịghị mma na ya, mgbe ahụ ọ ga-agbada ruo 30-40 g na n'okpuru. Enwere mgbanwe n’usoro nke anụ ahụ n’onwe ya. Ọrịa nke anụ ahụ na - ejikọta ya bụ njiri mara ọrịa ahụ.
Pancreatic atrophy pụtara n'ihi ihe ndị a:
- Ihe omume na-emebi emebi nke anụ ahụ.
- Mgbagha nke ọrịa shuga.
- Abụbiga mmanya ókè, ise anwụrụ.
- Ọrịa Duodenal, afọ.
- Oriri na-adighi nma.
- Ọrịa akụrụngwa na-emetụta oghere dị n'ime afọ.
- RV yiri.
Atrophic pancreatitis megide ọrịa shuga mellitus nwere ebe pụrụ iche. Ihe oria a bu otutu ihe di n’aru ya rue 20 g, nguzo ya na-abawanye, elu ya na –eme ka okpukpo aru, ka akpukpo ahu na aru ya aru ma mekwaa ya nso.
Lipomatosis na-egosikwa dị ka ụdị atrophic nke ọrịa pancreatic. N’agbanyeghi na oria a bu ihe aru di otua ma obu mmata ya, ma ihe dochie anya otutu ihe bu ihe glandular. N'ime pasent 80% nke ụdị ọrịa a, a na-echekwa ngwa ọrụ islet na ọrụ endocrine.
Ndị otu ahụ gụnyere ọrịa nwere ọrịa mkpụrụ ndụ, ị alcoholụbiga mmanya ókè, mmerụ ime, ọrịa na-efe efe nke akụkụ ahụ dị n'ime, ọgbụgba cholecystitis.
Clinical ngosipụta nke atrophy
Mgbe anyị nyochachara nchọpụta nke atrophy nke pancreatic, ihe ọ bụ, na ihe anụ ahụ nwere ike igbu atrophy, anyị ga-achọpụta ihe mgbaàmà na-egosi ọrịa. A na - ebute ọrịa site na etiology nke mmepe nke usoro a na - ahụ na - arịa glucose uptake, ụdị ọrịa na - adịghị ala ala nke pancreatitis, wdg).
N'agbanyeghị ihe kpatara ya na ihe na-akpata, n'ime ndị ọrịa niile enwere ụkọ nke endocrine na ọdịdị exogenous. Enweghi ike ị nweta ihe nzuzo dị na mwepụta nke mmepụta enzymes, electrolytes, nke na-enyere aka wepu ihe ndị dị n’ime afọ, na-enyere aka ị nweta gburugburu ebe obibi maka enzymes pancreatic.
Ndị ọrịa na-eme mkpesa maka mmebi nke usoro nri, nke a na-egosipụtakarị:
- Ọrịa afọ ọsịsa.
- Agụụ agụụ.
- Ibu ibu.
Ihe mgbaàmà izizi nke ike ọgwụgwụ nke exocrine na-abawanye bụ abụba abụba yana nri anụ ahụ. Achọpụtara ihe mgbaàmà a site na nzụlite mbelata nke nrụpụta site na 10% nke uru nkịtị.
Onye ọrịa na-amalite ifelata ngwa ngwa. Nke a bụ n'ihi eziokwu ahụ bụ na usoro nke ịgbari nri, ịmịkọrọ ihe na-edozi ahụ n'ime eriri afọ bụ ihe na-enye nsogbu, na agụụ na-ebelata. Ọ bụrụ na mmadụ nwere ajọ ọrịa atrophic pancreatitis na-adịghị ala ala, mgbe ahụ nyocha ụlọ nyocha gosipụtara ụkọ vitamin na mineral.
A na - achọpụta ezughi oke nke endocrine site na nsogbu metabolism metabolism nke na - eme dị ka hyperglycemic syndrome.
Agbanyeghị, naanị ọkara ndị ọrịa na-eme mkpesa maka mgbaàmà ọrịa shuga (mmịpụta ngwa ngwa, ọnụ akọrọ, iji ụlọ mposi ugboro ugboro, wdg).
Oria di iche
Mgbe ị na-enyocha onye ọrịa na 90% nke ihe osise ụlọ ọgwụ, a na-achọpụta ụkọ ibu. Akpụkpọ ahụ na-adị gịrịgịrị, kpọọ nkụ nke ukwuu. Otutu mgbe enwere ihe ndi nwere oria. N'otu oge ahụ, palpation anaghị enye gị ohere "inwe mmetụta" mbelata nke anụ ahụ.
Mgbe pathogenesis dabere na ihe na-eme pancreatitis, mgbe ahụ n’elu palpation onye ọrịa ahụ na-eme mkpesa banyere ihe mgbu na-egbu mgbu ma ọ bụ ahụ erughị ala. Nsonaazụ nke nyocha ọbara sitere na mmiri na-egosi na arụmọrụ nke enzymes diges.
Ihe coprogram na - enyere aka ịchọpụta abụba na feces (steatorrhea). Dịka iwu, a na-ahụ ihe karịrị 10% nke oriri kwa ụbọchị na feces. Onu ogugu akwara nke di na stool na abawanye karie, nke a bu ihe mmadu na-ezighi ezi.
N'ọtụtụ oge, ọmụmụ banyere mkpokọ glucose na-egosi mmụba dị ukwuu, nke chọrọ nleta ndị ọzọ na dọkịta dị ka endocrinologist ma ọ bụ diabetologist.
Otherzọ ndị ọzọ maka ịchọpụta ọrịa a:
- Na-eme nyocha ultrasound nke pancreas na-egosi mbelata ọnya ọgbụgba dị n'ime ahụ. Ihe owuwu a buru ibu, ihe akwara diwanye elu, ihe ana akaghizi agbanwe.
- A na-atụ aro MRI n'ọnọdụ ebe ultrasound na-enyebeghị ozi zuru ezu yana achọrọ nkọwa ndị ọzọ iji chọpụta usoro ọgwụgwọ kachasị mma.
- Edere RCP iji chọpụta ọnọdụ nke akwara mmiri, iji chọta mgbanwe ndị na-esokarị pancreatitis na-adịghị ala ala. Site na njikwa ọgwụgwọ dị otú a, ọ ga-ekwe omume ịchọpụta mbelata nke akwara azụ, ịta ahụhụ na enweghị mgbidi.
- Angiography di nkpa n ’ebe onye okacha mara dibia na-enyo oria tum tum. Usoro ahụ ga - enyere gị aka ịgbagha ma ọ bụ gosi na echiche ahụ.
Ọkpụkpụ nke bioreas bụ iwu. N'ime nyocha ụlọ nyocha nke ihe nlele ahụ weere, ogo nke fibrosis na mbibi nke parenchyma, a na-enyocha steeti nke glandular ihe na mpaghara ndị na-emepụta insulin.
Usoro nchọpụta a na-enye gị ohere ikwu ụda nke ọrịa.
Ọgwụ maka atrophy pancreatic
Na akara nke mbụ nke mgbanwe atrophic na pancreas, a na-atụ aro iri nri. Onye ọrịa ahụ kwesịrị ibelata iri nri nwere abụba anụmanụ.
Ọ dị mkpa ị attentiona ntị na enweghi protein ihe dị n’ime ahụ, ụkọ ike, yana idozi ụkọ vitamin na mineral. Ebe ọ bụ na nicotine so akpata ọgba aghara na mmepụta nke bicarbonates n'ime ahụ, a ga-atụfu sịga.
Ntụgharị uche kachasị nke ọgwụgwọ nchekwa na-esonye na ntụgharị ọgwụgwọ maka ọrụ nke exocrine na nzuzo intracecretory. A na-atụ aro ọgwụ enzymatic iji kwụọ ụgwọ maka usoro ndị a.
Iji nweta nsonaazụ ọgwụgwọ achọrọ, ekwesịrị ka amata ọgwụ ọgwụ site na oke ọrụ nke lipase, ekwesighi ibibi n'okpuru ihe ọ juiceụ gastụ afọ. N'okwu a, mbadamba mkpa itinye aka na ntopute nke enzyme ihe n'ime obere eriri afọ, iji na-akwalite usoro nri.
Microbeads na-agbaso ihe niile akọwapụtara. Ebe ọ bụ lipase na ngwa ngwa ga-efunahụ ọrụ, yabụ, a na-eme mgbazi n’iburu n'uche ọdịnaya ya na ọgwụ yana ike steatorrhea (oke abụba).
A na-ekpebi ịdị irè nke usoro ọgwụgwọ a tụrụ aro site na: ogo nke mbelata steatorrhea na ịta nke elastase na feces. Ndokwa Enzyme na - enyere aka ị nweta nsonaazụ ọgwụgwọ ndị a:
- Belata gelụ nke abụọ.
- Dezie microflora na eriri afọ.
- Mee ka metabolism na-arụ ọrụ nke ọma.
Iji belata ogo ihe mgbu, dezie ọgwụ ndị metụtara analgesics na antispasmodics. A na-ekpebi usoro onyonyo n'otu n'otu, dabere na ike nke ihe mgbu ahụ. A na-atụ aro inje nke Papaverine, No-shpu, Analgin na ọgwụ ndị ọzọ.
Iji dozie ezughi oke nke endocrine, iwebata insulin dị mkpa. Site na mgbanwe atrophic, a naghị achọpụta ọnwụ islet cell, ya mere, a na-emepụta homonụ ahụ, mana na ntinye uche dị ala. Odi na ugboro ole eji insulin agwọ ọrịa dabere na ọrịa, etiology nke ọrịa ahụ, nsonaazụ nke ọmụmụ ọmụmụ kwa ụbọchị nke glucose na ahụ.
Ọnọdụ dị mkpa bụ mgbazi nke ọrụ digestive, ọkachasị, nhazi nke microflora eriri afọ. Ya mere, a na-eji probiotics na prebiotics.
Ọzọkwa, a na-atụ aro maka ọgwụ nwere vitamin. Ọ dịkwa mkpa iji mejupụta adịghị ike nke ihe ndị a na - eme ịnweta:
- Magnesium
- Zinc
- Ọla kọpa.
Enwere ike ịkọwa ihe ndị ọzọ na-arụ ọrụ ihe ndị dị na biologically n'ụdị ọtụtụ ọgwụ, ma ọ bụ otu ọgwụ, n'otu oge ahụ gụnyere ihe ndị dị mkpa na ihe mejupụtara ya.
A na-arụ ọrụ ịwa ahụ na ụlọ ọgwụ pụrụ iche. Usoro a na –emegharị na ntughari nke agwaetiti nke Langerhans yana ụdị mmetọ ahụ na-esochi ma ọ bụ dozigharị enzyme.
Ebe ọ bụ na mgbanwe atrophic na pancreas bụ nsonaazụ nke ajọ ọrịa na nkwarụ siri ike nke ọnọdụ izugbe nke onye ọrịa, a na-edenyekarị ọgwụgwọ maka ịwa ahụ.
Amụma na Mgbochi Ya
Prognosis nke nsonaazụ nke ọrịa ahụ dabere na ogo mbibi nke ọrụ exocrine na intracecretory. Ebe ọ bụ na a na-echekwa obere akụkụ sel dị iche iche, ya mere, enwere ihe mkpopụta insulin. Ya mere, a naghị achọpụta ọnọdụ ketoacidotic, mana mbelata nke ọbara shuga na-amalitekarị.
Chọpụta ihe banyere usoro pathogenesis, iwepu “isi” - isi ọrịa, nnabata oge a ga - eme ya - isi ihe ndị a na - enye gị ohere inweta nsonaazụ ọgwụgwọ dị mma yana ịkọ ọdịmma.
Dịka prophylaxis, nyocha ndị ọrịa na-atụ aro iji ụzọ ọgwụ ọdịnala. Ha na-enyere aka melite arụ ọrụ nke pancreas, na-enyere aka melite mgbaze, na-egbochi nnukwu nsogbu na ahụ.
Maka usoro ọgwụgwọ, a na-eji osisi ọgwụ - hawthorn, dill, pepemint, chamomile ahịa, wdg Ntụziaka na-eso na-enyere aka ịkwado ahụ: jikọta tablespoons atọ nke mkpụrụ dill na otu mint, tinye 2 tablespoons nke hawthorn, otu tablespoon nke ụlọ ahịa ọgwụ chamomile. Yet esi mmiri. Iyo. Were 100 ml ugboro anọ n'ụbọchị. Usoro ọgwụgwọ ya bụ izu abụọ.
Dịka mgbochi, a na-atụ aro ịgbaso ndụmọdụ ndị a:
- Qukwụsị ise siga, mmanya.
- Treatmentgba oge n'oge nke ọrịa na-adịghị ala ala.
- Ezigbo nri na-edozi ahụ.
- Chekwa ọkwa achọrọ nke enzyme.
- Intanọgide na-ebi ndụ dị gara gara. Mmega ahụ na-eme ihe na-adịghị mma na pancreatitis, karịsịa yoga na ije, ga-aba uru nke ukwuu.
Atrophy nke pancreas bụ ọrịa siri ike, yabụ, mgbe enwere mmetụta nhụsianya na mpaghara epigastric, e kwesịrị ileta ụlọ ọrụ ahụike. Ngwa ngwa ngwa ọgwụgwọ ga-ebido, ihe ga-akacha mma ka amụma ahụ.
A kọwara ọrụ na ọrịa nke pancreas na vidiyo n'isiokwu a.
