Mbadamba ụrọ Rosucard: ntuziaka maka ojiji na nyocha nke ọgwụ

Rosucard na-ezo aka na akpụrụ akpụ nke na-eme ka ị nweta cholesterol nke ukwuu n'ọbara. Aha mba ụwa na-akwadoghị ọgwụ ahụ bụ Rosuvastatin (Rosuvastatin).

A na-agbaso ọgwụ ahụ n'ọrụ ọgwụgwọ hypercholesterolemia, mgbochi nke ịmepụta atherosclerotic plaques na ọrịa obi. Dọkịta na-ekpebi usoro ị theụ ọgwụ ahụ dabere n'ịdị ọcha nke ọrịa ahụ na njiri mara onye ọrịa ahụ.

Edemede a nwere ihe omuma banyere Rosucard (10.20.40 mg), ọnụahịa ya, nyocha ndị ọrịa na analogues.

Anddị na ihe mejupụtara ọgwụ ahụ

A na-ahụta Rosucard dị ka ọgwụ nke nwere mmetụta dị ala. Akụkụ nọ n'ọrụ na-egbochi mmepụta HMG-CoA reductase. Site na enzyme a, HMG-CoA na-agbanwe ka mevalonic acid, nke bụ usoro nke cholesterol.

Companylọ ọrụ Czech na-ere ọgwụ Zentiva na-ebu ọgwụ ahụ. A na-emepụta Rosucard n'ụdị mbadamba ihe mkpuchi na fim maka iji ọnụ. Mbadamba ụrọ ahụ nwere agba pink dị ọcha, ihe a na-akpọkọta ọnụ na akụkụ ya abụọ.

Akụkụ ike nke ọgwụ ahụ bụ rosuvastatin. Mbadamba nkume 1 nke Rosucard nwere ike ịnweta 10, 20 ma ọ bụ 40 mg nke ihe arụ ọrụ. Na mgbakwunye na nke a, ọgwụ ahụ nwere ihe enyemaka, ya bụ:

1. crosscarmellose sodium;
2. microcrystalline cellulose;
3. lactose monohydrate;
4. stereta magnesium.

Ihe nkiri a nwere ihe dika talc, macrogol 6000, oxide uhie, hypromellose na titanium dioxide.

Otu ọnya nwere mbadamba iri. A na-emepụta nkwakọ ngwaahịa otu, atọ ma ọ bụ itoolu. Mpempe akwụkwọ Rosucard na-etinye mpempe akwụkwọ ntinye mgbe niile maka mbadamba mbadamba.

Uzo oru ihe di nkpa

Ezubere rosuvastatin bụ iwelie ọkwa nke ndị na - anabata LDL na sel nke imeju parenchyma (hepatocytes). Mmụba na ọnụọgụ ha gụnyere mmụba na mbupute LDL, mbelata mmepụta VLDL yana mkpokọta cholesterol dị “njọ.

Mmetụta dị nro nke Rosucard na-adabere kpọmkwem na usoro eji eme ihe. Mgbe izu 1 nke ị theụ ọgwụ ahụ gasịrị, a na-ahụta mbelata nke cholesterol, mgbe izu abụọ gachara 90% nke mmetụta ọgwụgwọ kachasị ukwuu na-enweta. N’izu nke anọ, a na-ahụta ọnọdụ nguzogide nke nsị cholesterol.

Ọgwụ na - enyere aka ịbawanye ọkwa nke HDL, nke a na - adịghị atherogenic ma ghara itinye ya n'ụdị akwa na uto na mgbidi akwara.

Rome rosuvastatin kwa ụbọchị anaghị agbanwe ọgwụ ọgwụ. Ihe a na - emekọ ihe na - edozi ọbara (ma ọ dịkarịa ala na - ejikọ ya na albumin), nnabata na - apụta site na imeju. Otu akwara nwere ike ịgafe Plasenta.

Ihe dị ka 90% nke rosuvastatin na-ewepụ ahụ site na eriri afọ, nke fọdụrụ site na akụrụ. Ndị ọgwụ nke ngalaba na-arụ ọrụ anaghị adabere na nwoke na nwanyị.

Ihe ngosi na contraindications maka ojiji

Dọkịta na-edepụta Rosucard ma ọ bụrụ na ejikọtara nchọpụta onye ọrịa ya na cholesterol mụbara.

Amachibidoro ị -ụ onwe gị ọgwụ.

Enwere otutu ọrịa nke ọdịda nke metabolism metabolism na-akpata.

Iji mbadamba ụrọ dị mkpa maka:

• Hypercholesterolemia nke izizi ma ọ bụ agwakọta.
• Usoro ọgwụgwọ siri ike nke hypertriglyceridemia.
• Ezinaụlọ (ana - eketa eketa) homozygous hypercholesterolemia.
• Na-eme ka mmepe nke atherosclerosis (ịgbakwunye nri).
• Mgbochi ọrịa pathologies megide usoro nke atherosclerosis (obi mgbu, ọbara mgbali elu, ọnya obi na nkụchi obi).

A machibidoro iji ọgwụ nke ọgwụ nwere ọgwụ nke 10 na 20 mg na:

1. ọnụnọ nke uche mmadụ na akụkụ;
2. na-ebu nwata ma obu na-enye nwa ara;
3. erubeghị afọ 18;
4. mmepe nke myopathy (ọrịa neuromuscular);
5. ọgwụgwọ mgbagwoju anya na cyclosporine;
6. ọrụ enzyme nke CPK karịa ugboro ise;
7. ọjụjụ nwanyi jụrụ igbochi nke zuru oke;
8. ọdịda nke imeju na nnukwu akụkụ ahụ;
9. nhazi nke nje HIV na-egbochi mgbochi.

Enwekwara aha njiri mara contraindications maka onunu ogwu nke 40 mg:

• Ebumpụta ụwa maka myopathy.
• Mmanya na-egbu egbu na ị alcoholụbiga mmanya ókè.
• Ọdịdị ntaramahụhụ a na-akpọ ọdịdị.
• Myelotoxicity mgbe ị na-ewere HMG-CoA reductase blockers na fibrates.
• Thyroid malfunction.
• Ejikọtara ọnụ eji fibrates.
• Ọrịa dịgasị iche iche na-eduga na mmụba nke mkpokọta rosuvastatin n'ọbara.

Achọpụtaghị ya ka ị were ọgwụ were 40 mg site n'aka ndị nnọchi anya agbụrụ Mongoloid n'ihi ọnụnọ nke njirimara mmadụ.

Ntuziaka maka iji ọgwụ ahụ

Mkpa mbadamba ndị ahụ ekwesịghị ịta ma ọ bụ rie ata, mmiri riri ha. Medicineakingụ ọgwụ anaghị adabere n'oge ụbọchị ma ọ bụ oriri.

Tupu o dee Rosucard, dọkịta ahụ na-atụsi ike na onye ọrịa ahụ na-agbaso ụdị nri iji belata ego cholesterol riri.

Usoro ị dailyụ ọgwụ kwa ụbọchị bụ ọgwụ 0,5-1 (5-10 mg). Mgbe izu anọ gasịrị, dọkịta nwere ike ịbawanye ọgwụ ahụ. Mmụba na usoro ọgwụ kwa ụbọchị ruo 40 mg ga-ekwe omume naanị ma ọ bụrụ na cholesterol dị oke na enwere ike nke nsogbu nke ọrịa obi, mgbe ị ofụ ọgwụ kwa ụbọchị 20 mg adịghị arụ ọrụ.

Tebụl dị n'okpuru ebe a na-egosi atụmatụ nke iji Rosucard na ndị agbụrụ Mongoloid, yana ọrịa nke usoro biliary na nsogbu neuromuscular.

Ndụ shelf bụ ọnwa 24, mgbe oge a gasịrị, ị prohibitedụ ọgwụ a machibidoro iwu. A na-echekwa ngwakọ n'ebe ụmụaka dị obere na-enwe 25 Celsius.

Mmeghari Ahụhụ yana dofịkasị

Mmetụta akụkụ nwere ike ime mgbe ị na-a theụ ọgwụ.

Ọ bụrụ na mmeghachi omume ọjọọ na-eme, onye ọrịa ahụ kwesịrị ịkwụsị iji Rosucard ma gakwuru onye nlekọta ahụike.

Nsonaazụ ndị ọzọ na-adabere na usoro ị drugụ ọgwụ ahụ, ya mere, a na-ahụkarị ya n'ihi nchịkwa mbadamba ihe ị aụ ọgwụ 40 mg.

Ntụziaka ahụ nwere ozi ndị a gbasara ihe na-adịghị mma:

1. Ọrịa dyspeptik - ọgụ nke ọgbụgbọ na ọgbụgbọ, ihe mgbu na mpaghara epigastric, mgbe ụfọdụ mmepe nke pancreatitis na ịba ọcha n'anya.
2. Mmeghachi omume mkpụrụ ndụ - proteinuria (ọnụnọ protein na mmamịrị), hematuria (ọnụnọ ọbara na mmamịrị).
3. Ngosiputa ekpughere - itching, rashes na akpụkpọ, urticaria.
4. Ọkpụkpụ Musculoskeletal - olu mgbu, ọnya ọkpụkpụ, mbibi nke akwara akwara.
5. CNS dysfunction - migraine oge ụfọdụ, nkụda mmụọ, ụra na-adịghị mma na ụra abalị, ịda mba.
6. Mmebi nke akụkụ ọmụmụ - uto nke mammary glands na ụmụ nwoke.
7. Akpukpo anụ ahụ na mmeghachi ahụ anụ ahụ bụ ọrịa Stevens-Johnson syndrome (ma ọ bụ necrotic dermatitis).
8. Ọgba aghara na usoro endocrine - mmepe nke ụdị ọrịa shuga mellitus nke na-abụghị insulin.
9. Okuku iku ume - okpukpo akọrọ na ume iku ume.

Ebe ọ bụ na ọgwụ ọgwụ nke ike ihe arụ ọrụ abụghị ọgwụ ndabere, oke ị doesụbiga ihe ókè anaghị etolite. Mgbe ụfọdụ enwere ike ịbawanye ihe ịrịba ama nke mmeghachi omume ọjọọ.

Usoro ọgwụgwọ ahụ gụnyere usoro dị ka ọnya afọ, ojiji nke ịgba afa na iwepụ ihe mgbaàmà.

Ndakọrịta na ọgwụ ndị ọzọ

Ndakọrịta nke Rosucard nwere ụfọdụ ọgwụ nwere ike ibute mbelata ma ọ bụ nke ọzọ ga-eme ka arụmọrụ dị n'ọrụ rụpụta, yana nsonaazụ nke nsonaazụ ndị ọzọ.

Iji chebe onwe ya pụọ ​​na mmeghachi omume na-adịghị mma, onye ọrịa ahụ kwesịrị ịgwa dọkịta banyere ọrịa niile na ọgwụ a na-agakọ.

Ihe ndị a bụ tebụl nwere ndepụta nke ọgwụ ọgwụ ndị gọọmentị na-eme n'otu oge na-abawanye ma ọ bụ belata ọgwụgwọ ọgwụgwọ Rosucard.

Enwere ihe omuma na site na uzo siri ike nke Rosucard na Warfarin na ndi ozo nke vitamin K, ndi mmadu nwere mbelata nke INR.

Na nyocha nke sayensi, achọpụtaghị mmezi kemịkal dị iche n'etiti ihe ndị Rosucard na Ketoconazole, Fluconazole, Itraconazole, Digoxin, Ezetimibe.

Amachibidoro ị theụ ọgwụ na mmanya otu oge. Izere mmanya na sịga na-enyere aka belata cholesterol ka ọ dị mma.

Ego na inwe ndidi

Ebe ọ bụ na Rosucard bụ ọgwụ amịpụtara, ọnụ ahịa ya dị oke elu. N'agbanyeghị ịdị irè nke ọgwụ ahụ, ọnụahịa ya ka bụ ihe ndọghachi azụ.

Na nkezi, a pụrụ ịzụta Rosucard 10 mg (mbadamba 30) na ọnụahịa nke 595 rubles, 20 mg maka 875 rubles, 40 mg maka 1155 rubles. Iji chekwaa ego gị, ịnwere ike tinye usoro ntanetị na ntanetị nke onye nnọchi anya gọọmentị.

Ọtụtụ ndị ọrịa na-achọpụta mmetụta dị mma ọgwụgwọ site n'ị takingụ ọgwụ. Uru kachasị dị na ya bụ ụdị usoro ọgwụgwọ dị mma yana achọrọ maka naanị 1 oge kwa ụbọchị.

Agbanyeghị, enwere ike ịchọta nyocha na-adịghị mma nke ndị ọrịa na Internetntanetị.

Ndị na-agwọ ọrịa na ndị na-ahụ maka obi na-ejikọta mmeghachi omume ọjọọ na nnukwu usoro nke ọgwụ ahụ. Nke ahụ bụ ihe dọkịta N.S. kwuru Yakimets:

"Agụrụ m arụmọrụ nke ọnya a - ọ kwụzigharị ike ọria metabolism na usoro enweghị usoro na obere nsogbu, gbakwunyere na ya bụ ego, ma e jiri ya na ntụnyere Krestor. Enwere mmetụta ndị dị n'akụkụ, mana ha dị ụkọ, n'ihi na m na-edepụta 5-10 mg maka ịchọpụta obere nsogbu."

Mmechi na analogues nke ogwu

N'ọnọdụ ebe amachibidoro onye ọrịa iwere Rosucard n'ihi contraindications ma ọ bụ nsonaazụ ya, dọkịta na-ahọrọ dochie anya dị mma.

Na ahịa ọgwụ ị nwere ike ịchọta ọtụtụ mmekọrịta ọgwụ a, nke nwere otu ihe arụ ọrụ. Themfọdụ n’ime ha bụ:

• Rosuvastatin;
• Crestor
• Rosistark;
• Tevastor
• Akorta;
• Roxer;
• Rosart
• Mertenyl;
• Rosulip.

E nwekwara aha analogs nke di iche na ihe ndi mmadu na-aru oru, ma a gha ha n’otu n’ime statins:

1. Zokor.
2. Atoris.
3. Vasilip

Zokor. Na - etinye simvastatin ihe dị n'ọrụ, nke na - egbochi HMG-CoA reductase. Ọ bụ ụlọ ọrụ ọgwụ na USA na Netherlands mebere ya. Onu ogugu nke ngwugwu (Nke 28 10mg) bu 385 rubles.

Atoris. Nke a bụ analogue dị ọnụ ala nke Rosucard, n'ihi na ọnụahịa nke nkwakọ ngwaahịa (Nke 30 10mg) bụ 330 rubles. Ihe na-arụ ọrụ bụ atorvastatin, nke na-abawanye ọrụ nke ndị na-anabata LDL nke dị na imeju na anụ ahụ extrahepatic.

Vasilip. Ọgwụ nwere simvastatin na usoro nke usoro nke 10.20 na 40 milligrams. O nwere otu ihe egosi na contraindications dika Rosucard. Enwere ike ịzụta ọgwụ ahụ maka naanị 250 rubles (Mba. 28 10mg).

A kọwara ihe banyere ọgwụ ọjọọ eme ihe dabere na rosuvastatin na vidiyo ahụ n'isiokwu a.