N'ime usoro ọgwụgwọ dị mgbagwoju anya nke ọrịa ndị metụtara nsogbu n'ọbara, a na-egosipụta ojiji nke vasodilators, gụnyere Pentoxifylline.
Mgbe ị na-eji ọgwụ, a ga-ahụrịrị ntụzịaka ndị etinyebere na ya.
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A na-akwado nkwadebe Pentoxifylline maka iji gwọọ ọnya trophic, gangrene, angiopathy yana ndiiche na usoro nlegharị anya na ndị ọrịa nwere ọrịa shuga.
Ha weputara udi ya na ihe mebere ya
A na-eme ọgwụ ahụ n'ụdị mbadamba, dragees na ihe ngwọta ezubere maka infusions intravenous (droppers), injections and intramuscular management.
N'agbanyeghị ụdị ntọhapụ, ọgwụ ahụ bụchaghị isi ihe eji arụ ọrụ - pentoxifylline umi (na Latin - Pentoxyphyllinum).
N'okwu a, usoro onodu ogwu nwere ike di iche.
Ere ọgwụ
Mbadamba osisi a na-etinye n'ime ya nwere ọgwụ pentoxifylline 100 mg.
Ọgwụ a bụ otu nke vasodilators (vasodilators).
Ngwọta
Ngwọta a na-eji egbu egbu nwere milimita iri abụọ nke ihe na-arụ ọrụ n'ime 1 ml. A na-ere ọgwụ ahụ na ampoules nke 1, 2, 5 ml.
Jelii agwa
Dragees (retard) bụ capsules nke nwere akpụkpọ ihe nkiri pink. Na mbadamba 1 nwere 400 mg nke ihe eji arụ ọrụ.
Usoro nke ime ihe
Ọgwụ a bụ otu nke vasodilators (vasodilators).
Ebumnuche ọgwụ dị na ọgwụ ahụ bụ iji mee ka ọbara gbasaa ma melite akwara ọbara.
Ọgwụ a nwere mmetụta ndị a n'ahụ ahụ onye ọrịa:
- na-ebelata viscosity ọbara, na-ebelata ohere nke ọbara ọgbụgba;
- dilates arịa ọbara (obere oge), na-ewepu nsogbu na microcirculation ọbara;
- na-akwalite afọju anụ ahụ na oxygen, na-egbochi mmepe nke hypoxia (n'ihi mgbasa nke arịa ụkwara ume ọkụ na nke obi);
- na-abawanye ụda nke diaphragm, akwara umeji;
- nsonaazụ bara uru na ọrụ nke sistemụ ụjọ;
- Ọ na - enyere aka iwepụ ihe mgbu na mgbu n'ime akwara nwa ehi ndị metụtara nsogbu ọbara na aka.
Ọgwụ na-ebelata viscosity ọbara, na-ebelata ohere nke ịmịcha ọbara.
Mlọ ọgwụ
A na - etinye obi ihe ndị na - arụ ọrụ nke ọgwụ ahụ n'ime ọbara n'ọbara ma na - agbakasị ya na imeju. A na-ewepụ ihe ndị metụtara ọgwụ na ahụ n'ahụ ụbọchị site na akụrụ (ya na mmamịrị) na eriri afọ ya (yana oke ure).
Ihe na-enyere aka
A na-eji ọgwụ ahụ na ọgwụgwọ nke ọrịa ndị a:
- imebi ọbara ọgbụgba aka na aka na ụkwụ (syria Raynaud's syndrome);
- mmebi anụ ahụ n'ihi microcirculation ọbara na-arịa ya na akwara na akwara (ọnya akpụkpọ trophlebotic, ọrịa postphlebotic, gangrene);
- nkwarụ ọhụhụ na ntị nke metụtara enweghị ọbara ọgbụgba;
- ischemia nke ụbụrụ;
- Ọrịa Buerger (thromboangiitis obliterans);
- Enweghi ike nke sitere n’azu akụkụ ọmụmụ ọbara;
- atherosclerosis n'ụbụrụ;
- ọbara mgbali;
- angiopathy na ndị ọrịa na-arịa ọrịa shuga mellitus;
- akwara obi;
- ahịhịa dystonia ahịhịa;
- encephalopathy nke etiologies di iche iche.
A na-ejikwa ngwá ọrụ ahụ na ọgwụgwọ nke osteochondrosis dị ka vasodilator inyeaka.
Ihe ngbanwe
Ndepụta nke contraindications maka iji ọgwụ ahụ gụnyere:
- Ọrịa porphyrin;
- nnukwu myocardial infarction;
- ọbara ọgbụgba;
- nnukwu ọbara ọgbụgba.
Ejirighị ihe ngwọta a maka atherosclerosis nke akwara ụbụrụ na obi na nnukwu hypotension.
A na - ewepu ojiji nke Pentoxifylline na ndị ọrịa nwere hypersensitivity na mpaghara ahụ na - arụ ọrụ nke ọgwụ ahụ, ndị na - esonyere ya na ihe mejupụtara ya, ma ọ bụ ọgwụ ndị ọzọ sitere na otu xanthine.
Site na atherosclerosis nke akwara ụbụrụ na obi, ejila ọgwụ a n'ụdị edozi.
Etu ị ga-esi
Ọgwụ, dị n'ụdị dragees na mbadamba, bu n'uche maka nchịkwa ọnụ. Jiri ọgwụ mgbe nri gasịrị. Can nweghị ike ịta ata. A ga-eji obere mmiri wee hichaa ha.
Dọkịta na-ekpebi kpọmkwem usoro ọgwụ ahụ n'otu n'otu maka onye ọrịa ọ bụla, na-eburu n'uche njirimara nke ahụ ya na-adabere na data sitere na onyonyo onyonyo nke ọrịa ahụ. Usoro usoro onunu ogwu bu 600 mg kwa ubochi (200 mg ugboro ato kwa ubochi). Mgbe izu 1-2 gachara, mgbe akara ngosipụta nke nsogbu ahụ na-adịwanye njọ, a na-ebelata ubochi kwa ụbọchị na 300 mg (100 mg ugboro atọ n'ụbọchị). Ejila ego ole a tụrụ aro maka ọgwụ kwa ụbọchị (1200 mg).
Ogologo oge ọgwụgwọ na pentoxifylline na mbadamba nkume bụ izu 4-12.
Enwere ike ịhazi ihe ngwọta ahụ intramuscularly, intravenously na intraarterially. A na-ekpebi usoro onunu ogwu n’otu n’otu, na-eburu n’uche nsogbu ọgbasa akwara. Ntuziaka maka iji ọgwụ ahụ kwuru na ịkwesịrị iji ngwọta dị ka ndị a:
- Na ụdị nke ụmụ irighiri mmiri - 0.1 g nke ọgwụ a gwakọtara na salma 250-500 ml ma ọ bụ 5% gluuze gluu. Ọ dị mkpa iji nwayọ were ọgwụ ahụ, n'ime awa 1.5-3.
- Injections (intravenous) - na usoro ọgwụgwọ mbụ, a na-atụ aro 0.1 g nke ọgwụ (dilọm na 20-50 ml nke sodium chloride), mgbe ahụ, a na-abawanye ọgwụ ahụ ruo 0.2-0.3 g (agwakọta na 30-50 ml nke ihe mgbaze). Ekwesịrị iji nwayọ nye ọgwụ a (0.1 g maka nkeji 10).
- N'ime intramuscularly, a na-enye ọgwụ ahụ na usoro nke usoro 200-300 mg 2-3 ugboro n'ụbọchị.
Usoro usoro onunu ogwu bu 600 mg kwa ubochi (200 mg ugboro ato kwa ubochi).
Enwere ike ijikọ ihe ngwọta ya na nchịkwa ọnụ nke ụdị mbadamba ọgwụ ahụ.
Na-arịa ọrịa shuga
A na-akwado nkwadebe Pentoxifylline maka iji gwọọ ọnya trophic, gangrene, angiopathy yana ndiiche na usoro nlegharị anya na ndị ọrịa nwere ọrịa shuga. Agbanyeghị, ị ga-a takeụ ọgwụ ahụ naanị dịka dọkịta depụtara, onye na-edobe usoro onyonyo n’otu n’otu ma jide n’aka na ọ ga-agbanwe ya ma ọ bụrụ na onye ọrịa ahụ ewere ọgwụ hypoglycemic. -Medicationụ ọgwụ mgbochi onwe ya na pentoxifylline n'ọnọdụ a bụ ihe anabataghị, n'ihi na usoro ọgwụgwọ ahọpụtara n'ụzọ na-ezighi ezi nwere ike iduga mmepe nke mmeghachi omume na-adịghị mma (gụnyere hypoglycemic coma).
Pentoxifylline dị n’ịrụ ahụ
Ojiji Pentoxifylline nwere ike ịba uru ọ bụghị naanị na ọgwụgwọ nke ọrịa pathologies, kamakwa na egwuregwu, n'ihi na ọgwụ nwere ike ịbawanye arụmọrụ nke ọzụzụ, nwekwuo ntachi obi, mee ka mmezu nke nsonaazụ achọrọ n'ihi nsonaazụ bara uru n'ahụ.
Pentoxifylline nwere ike iwelie ịdị irè nke ọzụzụ, ịbawanye ntachi obi, mee ka mmezu nke ihe a chọrọ pụta dị ngwa.
A dụrụ ndị na-eme egwuregwu na ndị na-ahụ maka anụ ahụ ume ị takeụ ọgwụ a dị ka ndị a:
- Ọ dị mkpa ịmalite site na obere usoro iji - 200 mg 2 ugboro n'ụbọchị. Na-a pụ ọgwụ mgbe nri gasịrị.
- Ọ bụrụ na enweghị nsonaazụ yana nnabata ọ theụ ọgwụ dị mma, ịnwere ike ịbawanye usoro ubochi kwa ụbọchị ruo 1200 mg (400 mg ugboro atọ n'ụbọchị).
- Iji rụpụta nsonaazụ kacha mma, a na-atụ aro ka ị theụ ọgwụ ahụ nkeji 30 tupu mgbatị ahụ yana awa ole na ole mgbe ọ gwụchara.
- Oge ọ ga-eji ọgwụ ahụ bụ izu 3-4. Mgbe usoro ahụ gachara, ịkwesịrị ịhapụ izu maka ọnwa 2-3.
Nsonaazụ
Mgbe ị na-a theụ ọgwụ ahụ, anaghị egbochi mmeghachi omume ndị dị njọ site na akụkụ ahụ dị n'ime na sistem dị mkpa.
Ọkpụkpụ afọ
Ọgwụ nwere ike ibute mbufụt nke imeju, ya na ihe isi ike na ntiwapụ nke ihe ọnya na-egbu mgbu, na-eme ka ọrịa ọnya afọ na-akawanye njọ, na-akawanye motility eriri afọ, na-ebelata agụụ, yana mmetụta nke nkụ na-adị n'ime oghere ọnụ. N'ọnọdụ ndị a na-adịghị ahụkebe, a na-ahụ ọbara ọgbụgba n'ime.
Ngwá ọrụ nwere ike ibute mbufụt nke imeju, ya na ihe isi ike na mpụta nke ihe ndị na - adịghị mma.
Ahụhụ Hematopoietic
Mmeghachi omume ndị a na - esochi site na sistem okirikiri enwere ike:
- mbelata n'ọkwa platelet n’ime ọbara;
- wedata ọbara mgbali;
- obi mgbawa
- obi obibia nsogbu.
Sistemụ akwara Central
Mgbu afọ, isi ọwụwa, ọgbụgbọ, na ụra na-adịghị mma nwere ike ịme.
Onye ọrịa na-a theụ ọgwụ ahụ na-ewekarị iwe ma nwee oke nchegbu.
Ahụhụ
Mgbe ị na-a theụ ọgwụ, mmeghachi omume nfụkasị anụ ahụ (itching, urticaria) na ujo anafilactic kwere omume.
Mmeghachi omume ndị ọzọ
Enwere ike ịbelata na ọnọdụ nke ntutu, mbọ, ọzịza, ọbara ọbara nke anụ ahụ ('na-agbapụta' ọbara ruo ihu na obi).
Mgbe ị na-a theụ ọgwụ, mmeghachi omume nfụkasị anụ ahụ na ujo anafilactic nwere ike ịmalite.
A naghị agụpụ ihe ndị na-ahụ ụzọ anya na mmepe nke anya anya.
Ntụziaka pụrụ iche
A na-eji Pentoxifylline agwọ ọrịa na akpachapụ anya na ndị mmadụ na-arịa ọnya afọ nke afọ na duodenum, ọrịa akụrụ na imeju, obi na-ada, ma na-enwekarị ọbara mgbali dị ala. Maka ụdị ndị ọrịa a, ndozi usoro mmado chọrọ ya na njikwa ahụike siri ike n'oge usoro ọgwụgwọ dị mkpa.
Mmanya ndakọrịta
Ndị dọkịta kwusiri ike na ndị ọrịa na-a aụ ọgwụ dabere na Pentoxifylline ewezuga mmanya mmanya tupu njedebe nke ọgwụgwọ.
A na-atụ aro ka ekpochapụ mmanya tupu ọgwụgwọ Pentoxifylline emechaa.
Mmanya Ethyl na-enwe ike ike agị agịkọta ọnụ n’ime ọgwụ ọgwụ, wepụ ha ma ọ bụ mee ka ihe ndị dị n’ime ya rụ ọrụ, nke nwere ike ibute ịdị irè nke ọgwụ ma ọ bụ kpatara nsogbu.
Mmetụta ikike ịchịkwa usoro
Ọgwụ ahụ emetụtaghị ikike ịchịkwa usoro mgbagwoju anya, gụnyere ụgbọ ala, ọ bụrụ na ụfọdụ nsonaazụ (ọgbụgbọ, ọgba aghara ụra, wdg), ntinye uche onye ọrịa nwere ike ịka njọ. Nke a nwere ike belata ogo ịkwọ ụgbọala na ụgbọ ala ndị ọzọ.
N'oge ime na lactation
Mgbe ị na-enye nwa ara na n’oge ime, amachibidoro iji ọgwụ eme ihe. Ọ bụrụ na nwanyị na-enye nwa ara agaghị a takingụ ọgwụ ahụ, o kwesịrị ịkwụsị inye ya ara tupu njedebe ya.
Ihe enyere ndi umuaka aka
A mụọbeghị ịdị irè na nchekwa nke ọgwụ n'oge ọ bụ nwata, yabụ ndị na-emepụta Pentoxifylline akwadoghị ịdebanye ọgwụ a na ndị ọrịa na-erubeghị afọ 18.
A akwadoghị Pentoxifylline maka ndị ọrịa na-erubeghị afọ 18.
Agbanyeghị, na omume, ọ bụrụ na ọ dị oke mkpa, ndị dọkịta nwere ike ịkọtara ụmụaka ọgwụ a ka ụmụaka karịa afọ 12. Ọtụtụ mgbe nke a bụ n'ihi nsogbu mgbasa ọbara na adịghị ike nke iji usoro ọgwụgwọ ọzọ.
Usoro onunu ogwu n’oge agadi
N’oge agadi, mkpocha ọgwụ ahụ na-akwụsịlata, yabụ na-atụ aro ka iji ọgwụ ọnụọgụ belata.
Dodoụbiga ya ókè
Site n'iji ọgwụ ị highụ ọgwụ ọ highụedụ ogologo oge, ihe mgbaàmà ndị a nke ịdoụbiga mmanya ókè nwere ike ime:
- ọgbụgbọ, vomiting nke "kọfị ahịhịa" (na-egosi mmepe nke ọbara ọgbụgba);
- Dizziness
- adịghị ike
- ogwe.
N'okwu ndị dị oke njọ nke ị drugụbiga mmanya ókè, nkụda mmụọ, ịda mbà nke akụkụ iku ume, anaphylaxis.
N'ọnọdụ ndị siri ike karị, a na-ahụ nkụda mmụọ, nkụda mmụọ iku ume, anaphylaxis.
Mmekọrịta na ọgwụ ndị ọzọ
Ọgwụ nwere ike ịkwalite nsonaazụ ọgwụ ndị a:
- anticoagulants;
- thrombolytics;
- ọgwụ na-ebelata ọbara mgbali elu;
- ọgwụ nje
- insulin nwere ya na ọgwụ hypoglycemic;
- nhazi nke valvik acid.
Ojiji nke Pentoxifylline na ọgwụ nke nwere cimetidine na-ebulite ohere nke mmetụta ndị ọzọ. Nkwadebe nke dabere na ketorolac na Mexico adabaghị na Pentoxifylline, n'ihi na mgbe gị na ọgwụ na-emekọrịta ihe, ha na-amụba ohere nke ịmalite ịmịnye ọbara n'ime.
Nwere ike ịzụta ngwaahịa ahụ naanị ma ọ bụrụ na ịnwere ọgwụ ziri ezi dọkịta gị nyere gị.
A naghị atụ aro ka ikpokọta ojiji nke ọgwụ a na ojiji nke xanthines ndị ọzọ, ebe ọ bụ na nke a nwere ike ibute oké ụjọ ụjọ.
Analogs
N'ime usoro ọgwụgwọ nke ọrịa ọrịa na - akpata nsogbu, ana - eji ihe ana - echu Pentoxifylline:
- Cavinton;
- Trental;
- Pentoxifylline-NAS;
- Piracetam
- Pentilin;
- Mexicoidol;
- Fluxital;
- Latren;
- nicotinic acid.
Iji chọpụta nke ọgwụ ndị kachasị mma maka otu ọrịa mgbasa, ị kwesịrị ịkpọtụrụ dọkịta gị.
Emeputa
A na-emepụta ọgwụ ahụ na Russia site na ụlọ ọrụ ndị na-emepụta ọgwụ aha ya bụ Organka (Novokuznetsk) na Akrikhin (Moscow). Medicineslọ ọgwụ ndị Czech (Zentiva) na ụlọ ọrụ Israel (Teva) mekwara.
Ahịa ọgwụ na-ahapụ okwu
Nwere ike ịzụta ngwaahịa ahụ naanị ma ọ bụrụ na ịnwere ọgwụ ziri ezi dọkịta gị nyere gị.
Ọnụ ọnụahịa Pentoxifylline
Ọgwụ a na-emepụta na Russia nwere ọnụahịa dị ala - site na 40 ruo 150 rubles. Ọgwụ mbubata nke pentoxifylline na-akwụ ụgwọ ugboro abụọ karịa.
Ọnọdụ nchekwa
Ichekwa ebe echekwara n’aka umu aka, mgbe onodu ikuku kariri + 25 Celsius.
Ọgwụ a na-emepụta na Russia nwere ọnụahịa dị ala - site na 40 ruo 150 rubles.
Pentoxifylline
Enwere ike iji ngwá ọrụ ahụ rụọ ọrụ n'ime afọ atọ site na ụbọchị emepụtara.
Nyocha Pentoxifylline
Imirikiti ndị dọkịta na ndị ọrịa na-emeghachi omume n'ụzọ dị mma maka iji Pentoxifylline.
Ndi dibia
E. G. Polyakov, neurosurgeon, Krasnoyarsk
Ọgwụ nwere mmetụta dị mma n'ọrịa dịgasị iche iche nke mgbasa nke etiti na akwara. Ngwá ọrụ dị mma ma dị ọnụ ala, ya mere ọ bịara dịrị maka ụdị ndị ọrịa dị. Ọdịmma ọghọm nke ọgwụ ahụ gụnyere mmetụta adịghị ike na angiopathies.
Ndị ọrịa
Lily, onye gbara afọ 31, bụ Astrakhan
Tupu mgbe ahụ, m na-enwekarị nsogbu site na mwakpo nke dystonia ahịhịa na-emebi ahịhịa, nke metụtara ndụ m nke ukwuu. Ugbu a, a na-emeso m Pentoxifylline. Site na mwakpo nke na-esote, amalitere m iwere ọgwụgwọ a n'ụzọ (n'ime ụbọchị 10). Enyemaka na-apụta n’ụbọchị mbụ ọgwụgwọ, mgbe ụbọchị iri gachara, mgbaama niile na-apụ kpamkpam. A na-etinye uche pụrụ iche na ọnụ ahịa ọgwụ ahụ: ọ dị ala nke na mbụ ọ na-adị egwu. Mana ogo Russia Pentoxifylline adịghị njọ karịa nke analogues nke mba ọzọ, nke na-eri 2, ma ọ bụ karịa ugboro atọ karịa ọnụ.
Igor, onye gbara afọ 29, Volgograd
Iji mee ka microcirculation ọbara dị na akụrụ, a ga-ewere vasodilators.Edere Curantil na mbụ, mana isi ya tara ezigbo ahụhụ, yabụ na m ga-agbanye na Trental. Ndị a bụ ọgwụ ọgwụ dị mma, mana dịkwa oke ọnụ, yabụ m kpebiri iji dochie Pentoxifylline nke Russia. Ahụghị m ọdịiche ọ bụla (belụsọ maka ọnụahịa). Ha na-emekwa ihe, ha anaghị ebute mmeghachi omume ọjọọ, ha na-arụ ọrụ ha zuru oke.
