Tritace bụ otu ọgwụ na - alụ ọgụ. Ọgwụ nwere mmetụta dị mma na sistem ụbụrụ. Mmetụta a na –echebe ọnụnọ nke naanị otu ihe arụ ọrụ. Nwekwara ike iji ọgwụ a nwere ọrụ ezigharị arụ ya. Enwere ọtụtụ mgbochi n'ihe eji eme ihe, nke a bụ n'ihi oke arụrụ arụ na ahụ.
International Nonproprietary Aha
Ramipril. Aha ọgwụ a na Latin bụ Tritace.
Tritace bụ otu ọgwụ na - alụ ọgụ.
ATX
C09AA05 Ramipril.
Ha weputara udi ya na ihe mebere ya
Nwere ike ịzụta ọgwụ na usoro siri ike. Akụkụ bụ isi na ihe mejupụtara ahụ bụ ramipril. N'ime mbadamba 1, ihe dị n'ime 2.5,5 mg. Enwere nhọrọ ọnụọgụ ọgwụ maka ọgwụ ahụ: 5 na 10 mg. N’ime nsụgharị niile, ihe ndị pere mpe bụ otu. Ihe ndị a anaghị egosipụta arụmọrụ antihypertensive. Ndị a gụnyere:
- hypromellose;
- pregelatinized stachi;
- microcrystalline cellulose;
- sodium stearyl fumarate;
- dyes.
N'ime mbadamba 1, ihe dị n'ime 2.5,5 mg.
You nwere ike ịzụta ọgwụ ahụ na ngwugwu nwere blisters 2, na mbadamba iri na anọ ọ bụla.
Omume ọgwụ
Onye nnọchi anya nọ bụ angiotensin na - agbanwe enzyme inhibitor, ma ọ bụ ACE. Ọrụ kachasị ya bụ ime ka ọnọdụ dị n’ime obi na akụrụ daa. Ọzọkwa, ọ bụ naanị dose nke na-adịghị eme ka mbelata nrụgide ka enwere ike ịtụle ọgwụgwọ. Site na ya banye n'ime ọgwụ ahụ n’imeju, mgbanwe ya na-eme, yana ntinye nke metabolite nọ n'ọrụ - ramiprilat. Ngwakọta a na - enye arụmọrụ kachasị elu na igbochi ọrụ nke angiotensin na - atụgharị enzyme.
ACE na-akwalite mmebi nke bradykinin, nke na-eduga n'ọdịdị nke ọrịa pathologies site na nrụgide belata.
ACE na-akwalite mmebi nke bradykinin, nke na-eduga n'ọdịdị nke ọrịa pathologies site na nrụgide belata. N'oge usoro ọgwụgwọ na onye nnọchite ahụ, a na-egbochi usoro a. N'ihi mkpokọ nke bradykinin, a na-achọpụta mmụba nke lumen arịa ọbara yana mbelata mgbali. Na mgbakwunye, mgbe ị na-a theụ ọgwụ ahụ, a na-eme ka njikọ nke prostaglandins rụọ ọrụ. N'ihi ya, a na-enye nsonaazụ cardioprotective.
Mmetụta ọzọ nke isi ihe dị na ngwakọta nke ngwá ọrụ a bụ iji belata mmepụta nke angiotensin II. Na nke a, a na-achọpụta mmụba nke mkpo potassium ion na plasma ọbara.
Site na ị thisụ ọgwụ a na-achịkwa achịkwa, ihe ize ndụ nke ịmalite hyperkalemia na-abawanye.
Mlọ ọgwụ
Ọgwụ a na-atụgharị amalite ime ihe nkeji 60-120 mgbe iwere mbadamba mbido mbụ. Ọnụ ọgụgụ kachasị elu nke ọrụ na-eme mgbe awa ole na ole gasịrị (site na 3 ruo 9). A na-ahụzi nsonaazụ ya na-adị 1 ụbọchị. Site na ọgwụgwọ ogologo oge, enwere ike nweta ọnọdụ kwụsiri ike na izu ole na ole, na njedebe nke usoro ahụ, nsonaazụ dị mma na-adịgide ruo oge ụfọdụ.
Ọgwụ ahụ na-amị amị ahụ na mucous nke ọnya nri na oke agaghịfe 60% nke ngụkọta oge.
Ọgwụ ahụ na-amị amị ahụ na mucous nke ọnya nri na oke agaghịfe 60% nke ngụkọta oge. Mbadamba nwere ike iwere oge ọ bụla (tupu nri ma mgbe emesịrị nri). Nke a anaghị emetụta ogo nke ọgwụ a, mana ọ na-eji nwayọ nwayọ nwayọ. Nke a pụtara na enwere ike nweta nsonaazụ dị mma mgbe oge ụfọdụ gasịrị site na iji ọgwụ ahụ n'oge ma ọ bụ ozugbo nri.
Bioavailability nke isi ihe dị na mejupụtara ahụ dịgasị n'etiti 15-28%, nke a na-ekpebi site na usoro onunu ogwu. A na-ewepụ ihe ahụ na ọkwa, usoro ahụ dum nwere ike iwe ụbọchị 4-5. N'otu oge ahụ, itinye uche ya na serum ji nwayọọ nwayọọ belata. A na-ekepụta metabolites nke ọgwụ a na-atụle site na akụrụ n'oge urin.
Ihe enyere n'iwu
Ọtụtụ ihe na-egosi maka iji ọgwụ a:
- ọbara mgbali (akwara na ọnya);
- nkụchi obi, na nke a, a na-enye ọgwụ ahụ naanị dịka akụkụ nke ọgwụgwọ mgbagwoju anya;
- sistemụ na-akpata nsogbu, ndị ọrịa shuga kpatara;
- mgbochi pathologies nke akwara obi (ọrịa strok, infarction myocardial, wdg) n'ime ndị ọrịa nwere nnukwu ihe ize ndụ nke ụdị ọrịa ahụ;
- cardiac ischemia, tumadi, ogwu di nkpa maka ndi mmadu meriri oria myocardial infarction, coronary artery byver grafting or angioplasty of arteries;
- ọnya ọnya ọrịa na-akpalite mgbanwe na ntọala nke mgbidi akwara mmiri.
Ihe ngbanwe
Uzo ọghọm nke akụrụngwa a gụnyere ọtụtụ mgbochi maka ojiji nke:
- ebumnuche ịzụlite ọrịa angioneurotic na mmeghachi omume dịgasị iche iche;
- warara nke akwara nke akụrụ, akwara ma ọ bụ mital valvụ, nke a hụrụ na ọnọdụ ike;
- hypotension akwara;
- isi hyperaldosteronism;
- nephropathy, nyere na n'ọnọdụ a, a na-eji ọgwụ ọgwụgwọ GCS, NSAIDs na ọgwụ cytotoxic ndị ọzọ eme ihe.
Jiri nlezianya
Ọtụtụ ndị na - egbochi contraindications:
- mgbanwe atherosclerotic na mgbidi akwara;
- ọrịa obi na-adịghị ala ala;
- ụbụrụ ọbara;
- imechi akwara nke akwara nke akwara di omimi, ma oburu na usoro a aputara naani otu uzo;
- nchịkwa ọgwụ ọgwụ diuretic n'oge na-adịbeghị anya;
- enweghi mmiri n’arụ megide ọgbụgbọ, afọ ọsịsa na ọrịa ndị ọzọ;
- hyperkalemia
- ọrịa shuga mellitus.
Uzo esi ewere Tritace
Mbadamba nkume ihu igwe ekwesịghị. A na-ahọrọ usoro ọgwụgwọ na-eburu n'uche ọnọdụ ọrịa. N'ọnọdụ ka ukwuu, a na-eji nwayọọ nwayọọ na-abawanye were were ihe a na-arụ ọrụ. Ọtụtụ mgbe etinyere 1.25-2.5 mg nke ihe mejupụtara a 1 oge kwa ụbọchị. Mgbe oge ụfọdụ gasịrị, ọnụ ọgụgụ ọgwụ ahụ na-abawanye. N'okwu a, a na-ekpebi dose ahụ n'otu n'otu maka onye ọrịa ọ bụla, na-eburu n'uche mgbanwe nke ọrịa ahụ. Obere oge, a na-amalite ọgwụ 5 ọgwụ nke ọgwụ.
Na-arịa ọrịa shuga
A na-eji ngwa ahụ na ọnụọgụ akarịghị 1.25 mg kwa ụbọchị. Ọ bụrụ na ọ dị mkpa, a na-abawanye ọgwụ a. Agbanyeghị, ọgwụ a na-enweta mkpoghachi izu 1-2 ka mmalite nchịkwa gasịrị.
Na-arịa ọrịa shuga, a na-eji ọgwụ ahụ na ọnụọgụ anaghị akarị 1.25 mg kwa ụbọchị.
Nsonaazụ
Reactionsfọdụ mmeghachi omume na-etolite ugboro ugboro, ndị ọzọ anaghị enwekarị. N'oge usoro ọgwụgwọ, onye a na-eche echiche na-emetụta usoro na akụkụ dị iche iche. Mgbe ụfọdụ enwere mmụba n’ọkpụkpụ azụ, ọrịa febrile na-apụta.
Ọkpụkpụ afọ
Ọrịa, nri nke nri, afọ mgbu, ọgbụgbọ na ọgbụgbọ, nza nke mucous membranes nke afọ, oche siri ike, pancreatitis, obere oge na-egbu egbu.
Sistemụ akwara Central
Isi ọwụwa, isi ọwụwa, iyi nke akụkụ ya, belata uche, mbelata nguzo ọtọ, ọrịa akwara ozi, yana nsogbu ọbara.
Site n'akụkụ akụkụ akwara dị n'etiti, enwere ike inwe isi ọwụwa mgbe ị nwusịrị Tritace.
Site na usoro urinary
Mgbanwe na ọkwa nke creatinine na urea n'ime ọbara, nrụrụ gbasara akụrụ, mmụba nke nrụpụta mmamịrị.
Site na sistem iku ume
Mgbu, tonsillitis, sinusitis, bronchitis, ọdịda iku ume n'ihi mkpọchi imi na bronchospasm.
Na anụahụ
Nzuzo, mbufụt, nfụkasị na ihe mgbochi ụzọ ikuku, dermatitis, necrolysis, mmeghachi omume fotoensitivity.
N’akụkụ anụ ahụ, enwere ike inwe ihe mgbawa mgbe ị nwusịrị Tritace.
Site na usoro mkpụrụ ndụ ihe nketa
Mmebi emebi, na-emegide nzụlite nke enweghi ike, ana-ahụta mbelata nke libido. N'ime ụmụ nwoke, gland mammary nwere ike ịba ụba.
Site na usoro akwara obi
Obi ọgbụgba obi, ọrịa obi akwara akwara, infarction myocardial, ọzịza n'ihi njigide mmiri, mbelata mgbali mgbali, mgbasa ọbara.
Usoro endocrine
Mmebi nke usoro ndu mmiri: enwere mbelata ma ọ bụ mmụba na ịta ihe dị iche iche (sodium, potassium, magnesium, calcium).
Site na usoro akwara, enwere ike ịnwe akwara olu mgbe ị gbasịrị Tritace.
N'akuku nke imeju na akụkụ biliary
Gbanwee na ọnụọgụ nke ọnwa bilirubin na enzymes imeju, ọbara ọgbụgba, ọrịa ịba ọcha n'anya.
Site na usoro akwara na uru ahụ
Akwara ahu, arthralgia, myalgia.
Site n'akụkụ nke metabolism
Ọrịa alkaabol.
Site na usoro ahụ ji alụso ọrịa ọgụ
Ọdịnaya nke ọgwụ antiinuclear na-abawanye, mmeghachi omume anaphylactoid na-etolite.
A naghị atụ aro ka ọ kwọọ ụgbọ ala n'ihi oke ihe ize ndụ nke mmeghachi omume na-adịghị mma.
Ahụhụ
Urticaria, tinyere itching, ihe ngbu, imecha ihe nkebi nke mpụga na mpụta.
Mmetụta ikike ịchịkwa usoro
A naghị atụ aro ka ọ kwọọ ụgbọ ala n'ihi oke ihe ize ndụ nke mmeghachi omume na-adịghị mma.
Ntụziaka pụrụ iche
Ọrịa a na-ekwu okwu adịghị ya otu oge. Ọ dị mkpa ka akagbuo ha ụbọchị 2-3 tupu mmalite nke agụmakwụkwọ.
Tupu ịmalite ọgwụgwọ, ị ga-elele ma ọnọdụ ọrịa dịka hyponatremia na hypovolemia na-etolite.
Iji zere ọdịdị nke mmeghachi omume na-adịghị mma, mgbe mmalite nke usoro ahụ yana mmụba na dose ahụ, ọ dị mkpa iji nyochaa ọnọdụ onye ọrịa ahụ.
N'oge ọgwụgwọ, a na-enyocha ọbara ọgbụgba mgbe niile, ọkachasị ndị ọrịa nọ n'ihe ize ndụ.
Iji zere ọdịdị nke mmeghachi omume na-adịghị mma, mgbe mmalite nke usoro ahụ yana mmụba na dose ahụ, ọ dị mkpa iji nyochaa ọnọdụ onye ọrịa ahụ.
N'ọnọdụ dị njọ (ọrịa obi), a na-enye ọgwụ ahụ naanị mgbe ọ gachara ụlọ ọgwụ.
Jiri n'oge ime na lactation
A naghị eji ngwa ahụ eme ihe mgbe ị na-ebu nwata na inye ya ara.
Ibido Tritace nye Childrenmụaka
Enweghị ahụmịhe banyere iji ọgwụ iji gwọọ ndị ọrịa na-erughi afọ ole ha.
Jiri na agadi
Ndị ọrịa nọ n’òtù a kwesịrị ịkpachara anya, n’ihi na enwere nsogbu iwelata nrụgide siri ike.
Ngwa maka ọrụ ezughi oke ọrụ
Nje contraraindications bu nje di egwu nke aru a. Edeghị ọgwụ ahụ na mbelata nwebipụta creatinine ruo 20 ml / min.
N’oge agadi, ọ kwesịrị ịkpachara anya, ebe ọ bụ na enwere nsogbu nke mbelata nke nrụgide siri ike.
Jiri maka ọrụ imeju na-arụ ọrụ
A na-eji ọgwụ ahụ n'okpuru nlekọta nke dọkịta, ọ bụrụ na ọ dị mkpa, a na-amaliteghachi kwa ụbọchị.
Dodoụbiga ya ókè
N'ihe banyere ịdoụbiga ihe ókè, ọbara ọbara na-ebelata nke ukwuu, ujo, obi obi (bradycardia) nwere ike ịmalite. Mgbaàmà nke mgbanwe na mmiri-electrolyte itule, ọdịda akụrụ.
Nke mbụ, ịkwesịrị iwepu ọgwụ ọjọọ ya na afọ, nke a na-asa ahụ. Mgbe ahụ ịkwesịrị ị were adsorbent. Mgbe nke a gasịrị, a na-enye ọgwụ ọgwụgwọ Symptomatic.
Mmekọrịta na ọgwụ ndị ọzọ
Nyere mmetụta ọjọọ nke ọgwụ a na-ekwu okwu, ọ kwesịrị ịkpachara anya mgbe ị na-ahọrọ ọgwụ maka ọgwụgwọ dị mgbagwoju anya.
Ọ bụrụ na ị doụbiga ihe ọ ,ụ overụ, akwara nwere ike ịmalite.
Ngwakọta ndị amachibidoro
Ejila sulfate dextran, membran polyacrylonitrile.
Ngwakọta anaghị atụ aro
Ọ bụrụ na enwere ike, ahọpụtara ọgwụ na ọgwụ ndị ọzọ. Ekwesighi iji ọgwụ ajuju ya na nnu nnu lithium, potassium na diuretics, nke na-abawanye uto nke potassium, yana ogwu ihi ura.
Mgwakọta chọrọ ịkpachara anya
Otu a gụnyere ọgwụ ndị na - eduga n'ibe nrụgide. Ọ dị mkpa iji hụ mmeghachi omume anụ ahụ mgbe ị na-eji heparin, ethanol na sodium chloride.
A naghị atụ aro ịrinụ mmanya nwere ihe ọ alcoholụ alcoholụ na-egbu egbu tinyere ngwaahịa a na-ekwu okwu ya.
Mmanya ndakọrịta
A naghị atụ aro ịrinụ mmanya nwere ihe ọ alcoholụ alcoholụ na-egbu egbu tinyere ngwaahịa a na-ekwu okwu ya.
Analogs
Iji ọgwụ dochie anya:
- Hartil;
- Dilaprel;
- Ahapu;
- Diroton;
- Lipril, wdg.
Ọ dị mkpa ịhọrọ ọgwụ ndị ejiri obere mmetụta mara, mana n'otu oge ahụ na-enyere aka na steeti na-arịa ọbara mgbali elu ma na-eduga mkpali nke ọbara mgbali elu.
Ọnọdụ ezumike Tritace sitere na ụlọ ahịa ọgwụ
Ogwu bu otu ogwu eji eme ogwu.
Enwere m ike ịzụta na ndenye ọgwụ
Enweghị ụdị dị otú ahụ.
Ogwu bu otu ogwu eji eme ogwu.
Ọnụahịa na Tritac
Ọnụ ego dị iche n'etiti 1000-1250 rubles.
Ọnọdụ nchekwa maka ọgwụ
Na-atụ aro ụlọ okpomọkụ - ruo + 25 Celsius С.
Bọchị mmebi
Mbadamba nwere 2.5 na 5 mg nwere ike ịchekwa ya afọ 5. Enwere ike iji ngwaahịa a nwere mkpokọta 10 mg nke ihe na-arụ ọrụ n'ime mbadamba 1 ọ gafere afọ 3 site na ụbọchị mbipụta.
Tritace rụpụtara
Aventis Pharma Deutschland GmbH, Germany.
Nyocha banyere Tritac
A na-atụ aro ka ị nweta ihe niile o kwere mee banyere ọgwụ a. Nke a na-enyere aka nyocha nke ndị ahịa na ndị ọkachamara.
Ndi dibia
Zafiraki V.K., akwara gbasara obi, 39 dị afọ, Krasnodar
Site na usoro a na-achịkwa maka usoro akwara obi, ọgwụ a na-arụ ọrụ nke ọma: ọ na - eme ka ọbara mgbali elu ma ghara ịkpalite nsonaazụ. Agbanyeghị, n'ọtụtụ ndị ọrịa, a na-achọpụta ọrịa na-efe efe, n'ihi nke ọ bụ nsogbu ịkọ ọgwụ ka ọ dị - a chọrọ nlebara anya banyere ọnọdụ ahụ mgbe niile.
Alanina E. G., onye na-ahụ maka ọgwụgwọ, gbara afọ 43, Kolomna
Ekwesịrị ị takenụ ọgwụ a dosed, ị nweghị ike iwelie ego kwa ụbọchị, ị ga-enyocha ahụike gị. Mgbe ihe mgbaàmà mbụ na-adịghị mma pụtara, a na-akwụsị ụzọ ọ ga-esi gwọọ ya. Agaghị m agbagha ịdị irè nke ọgwụ ahụ, mana m na-agbalị ịkọ ya ka ọ bụrụ obere oge, n'ihi na enwere nnukwu ihe ize ndụ nke ịmalite nsogbu ndị siri ike.
Ndị ọrịa
Maxim gbara afọ 35, Pskov
Mgbe ụfọdụ ana m a theụ ọgwụ, maka na m na-arịa ọbara mgbali ogologo oge. Ọ na-eme ihe ọsọ ọsọ. Dọkịta tiri obere ọgwụ, n'ihi na enweghị m ọnọdụ ọjọọ. Maka nke a, mmetụta ndị ahụ etabeghị.
Veronika, 41 afọ, Vladivostok
N'ihi nsogbu nke arịa, nrụgide na-amapụkarị. M oge na-agbanwe ọgwụ antihypertensive ọgwụ na nkwanye dọkịta. Agbalịrị m ị differentụ ọgwụ dịgasị iche. Ọgwụ a na-a questionụ ọgwụ dị irè nke ukwuu, n'ihi na a na-ahụ nsonaazụ ya ngwa ngwa. Ma nke a bụ ihe eji eme ihe ike. M na-eji ya erughị ugboro karịa analogues.
