Ezubere mbadamba Glibomet bụ maka ndị ọrịa nwere ọrịa mellitus na-arịa insulin na-akpata (ụdị II). Nsonaazụ jikọtara ọnụ na-enye gị ohere nweta oke kachasị na ọgwụgwọ nke ọgwụ a.
International Nonproprietary Aha
Metformin + glibenclamide (metformin + glibenclamide).
ATX
A10BD02.
Glibomet dị n'ụdị mbadamba ihe na shei.
Ha weputara udi ya na ihe mebere ya
Ere ọgwụ na shei. Ngwunye ọrụ na-arụ ọrụ n'ime mbadamba 1: 2.5 mg glibenclamide, 400 mg metformin hydrochloride. Ihe ndi ozo:
- microcrystalline cellulose;
- ọka ọka;
- steeti magnesium;
- talc;
- diethyl phthalate;
- cellulose acetate;
- colloidal silicon dioxide.
Omume ọgwụ
Ọgwụ a nwere ọtụtụ ọgwụ ọgwụ hypoglycemic jikọtara ọnụ. Ọ nwere mmetụta extrapancreatic na pancreatic.
Glidenclamine bụ ihe dị n'ọgbọ dị n'ọbara sọlfọlurea 2. Ọ na - eme ka insulin na - arụ ọrụ nke ọma na - eme ka ndị na - anabata beta nke pancreas, na - eme ka insulin na - eguzogide ọgwụ na - eme ka nnwale insulin na ọrụ nke insulin na - emetụta mkpokọ glucose site na imeju na akwara, na - eme ka usoro lipolytic dị na akụkụ nke anụ ahụ adipose.
Metformin bụ biguanide. Ihe a na –eme ka mmata nke akụkụ anụ ahụ dị na nsonaazụ insulin, belata ogo nnabata nke glucose na usoro nri ma nwee mmetụta inhibitory na gluconeogenesis. N’ihi nke a, a na-ahụkarị ọgwụ na-egbu egbu, na -ebelata ibu n’arụ ndị ọrịa mamịrị.
Ọgwụ a nwere ọtụtụ ọgwụ ọgwụ hypoglycemic jikọtara ọnụ. Ọ nwere mmetụta extrapancreatic na pancreatic.
Mlọ ọgwụ
A na-etinye Glibenclamide kpamkpam na ngwa ngwa mgbidi nke eriri afọ. Oge ị ga-eru Cmax sitere na minit 60 ruo 120. Ọ bụ nke bile na akụrụ ya n’olu dị nha hà. Ọkara ndụ na-adị n'etiti awa 5-10.
Site na akụkụ eriri afọ na-abanyekwa Metformin. Anụ ahụ anaghị agbaji. Ọ napụtara ya site na akụrụ n'ụdị mbụ ha. Iwepu ọkara ndụ na-erute awa asaa.
Ihe ngosi maka ojiji
A na-eji ọgwụ ahụ agwọ ọrịa ụdị ọrịa shuga mellitus nke 2 (insulin-dependance) na enweghị ọnọdụ dị mma sitere na monotherapy na ọgwụ hypoglycemic ndị ọzọ na usoro ọgwụgwọ nri.
A na-eji ọgwụ ahụ agwọ ụdị ọrịa shuga 2.
Ihe ngbanwe
- ọrịa ndị na-egbu mgbu na-esonyere nbibi n'ọrụ nke akụrụ / imeju ma ọ bụ ịtụnanya hypoxic;
- mmadụ inwere onwe ya;
- nnukwu nsị nke imeju;
- akpịrị coma / precoma;
- oge ị breastụ ara na / ma ọ bụ afọ ime (jiri nlezianya);
- ụdị ọrịa mamịrị ketoacidosis;
- oké hypoglycemia;
- lactic acidosis;
- Type 1 insulin-based diabetes diabetes mellitus.
Uzo esi ewere Glibomet
Ana-eji mbadamba nkume ndị ahụ. Nri n’eme ka mmata nke ogwu. A na-enye usoro onunu ogwu n'otu oge, na-eburu n'uche ịta ụta plasma nke ọbara n'ọbara na oke ike nke metabolism.
A na-enye usoro onunu ogwu n'otu oge, na-eburu n'uche ịta ụta plasma nke ọbara n'ọbara na oke ike nke metabolism.
Na-a drugụ ọgwụ maka ọrịa shuga
Nkezi mbido ọgwụ sitere 1 mbadamba mbadamba 3 kwa ụbọchị, mgbe ahụ usoro a ga-eji nwayọ mụbaa ruo mgbe egosiri ịgwọ ọrịa ahụ. Oke kachasị ọgwụ kwa ụbọchị bụ mbadamba ise kwa ụbọchị.
Nsonaazụ Glybomet
Ọkpụkpụ afọ
- ịba ọcha n'anya;
- jalestice cholestatic;
- vomiting
- imebi afọ;
- obere ọgbụgbọ.
Ahụhụ Hematopoietic
- mbelata nke ọkwa nke ọbara ọbara, sel ọbara yana platelet (adịkarịghị);
- megaloblastic / hemolytic anaemia.
Sistemụ akwara Central
- mbelata nke uche;
- paresis (n'ọnọdụ ndị na-adịghị ahụkebe);
- nhazi ụdọ;
- isi ọwụwa.
Site n'akụkụ nke metabolism
- enwere ihe ize ndụ nke ịmalite hypoglycemia.
Na anụahụ
- hypersensitivity na ìhè (adịkarịghị),
Ahụhụ
- ihe odide
- ọzịza;
- nfụkasị rhinitis;
- mmụba nke okpomọkụ;
- nkwonkwo na akwara mgbu.
Ọgwụ nwere ike bute mgbu na akwara na nkwonkwo.
Mmetụta ikike ịchịkwa usoro
N'oge ị na-ewere mbadamba mbadamba, enwere ike hypoglycemia, yabụ, a ga-ezere ịchịkwa igwe na usoro ndị a.
Ntụziaka pụrụ iche
Mgbe ị na-a theụ ọgwụ ahụ, mmadụ ga-ekwenye nke ọma na ndụmọdụ dọkịta na usoro nke usoro usoro usoro ọgwụ na usoro onunu ogwu. Na mgbakwunye, n'oge ọgwụgwọ, ọ dị mma ịgbaso nri, mepụta atụmatụ nke mmega ahụ ma na-enyocha glucose ọbara mgbe niile.
Ngwakọta nke metformin na-akpali mmụba nke mkpokọta lactic acid n'ime ọbara, nke nwere ike ibute ọnọdụ dị ize ndụ dị ka lactic acidosis. Yabụ, mgbe ị na-a theụ ọgwụ ahụ, a ga-ewepụ ihe ndị dị ize ndụ dịka ibu ọnụ ogologo oge, ọkwa nke ọrịa shuga, ị alcoholụbiga mmanya ókè na ọnọdụ ọ bụla ọzọ metụtara hypoxia.
Iji gbochie acidicis, a ga-ezere ibu ọnụ ogologo oge n'oge ọgwụgwọ Glibomet.
Jiri n'oge ime na lactation
Amachibidoro. Oge ịgwọ ọrịa ara ga-ezere.
Ndenye ọgwụ glybomet maka ụmụaka
Mbadamba adịghị eji agwọ ndị ọrịa afọ ha na-erughi afọ 18.
Jiri na agadi
Ọchọghị usoro ọgwụgwọ usoro onunu ogwu.
Ngwa maka ọrụ ezughi oke ọrụ
Site na nhazi oge nke diuretics na ọgwụ antihypertensive, ekwesịrị ịkpachara anya. Na mgbakwunye, ekwesịrị ilebara nwepu nke creatinine maka ndị ọrịa nwere akụrụ nsogbu.
Jiri maka ọrụ imeju na-arụ ọrụ
Ndị ọrịa nwere ọrụ imeju na-adịghị arụ ọrụ kwesịrị iji ọgwụ ahụ nke ọma.
Ndị ọrịa nwere ọrụ imeju na-adịghị arụ ọrụ kwesịrị iji ọgwụ ahụ nke ọma.
Glybomet overdose
Ihe odide njirimara: enwere ihe ize ndụ nke hypoglycemia na lactic acidosis. E gosipụtara ọrịa ndị a site na mgbaàmà ndị a:
- vomiting
- ike;
- enweghị mmasị
- ibelata ọbara mgbali elu;
- imebi usoro ntụpọ;
- ọsụsọ
- mmụba obi;
- pallor nke akpụkpọ ahụ;
- ịma jijiji
- ọgbụgbọ
- bradyarrhythmia (reflex);
- mgbakasị ahụ n’ime oghere dị n’afọ;
- nsogbu ụra;
- Nchekasị
- iro ụra
Site na enyo ọ bụla nke lactic acidosis na hypoglycemia, onye ọrịa chọrọ ụlọ ọgwụ ozugbo.
Iji ụdị hypoglycemia dị nwayọọ, ịkwesịrị iri obere shuga ma ọ bụ drinkụọ mmanya dị ụtọ. Nke a ga-ahazi ọrụ nke pancreas.
Ofzọ ọgwụgwọ kachasị dị irè bụ usoro ọgwụgwọ metụtara akwara ụkwụ.
Mmekọrịta na ọgwụ ndị ọzọ
Ndị na-egbochi ọgwụ, allopurinol, oxytetracycline na dicumarol na-abawanye ọrụ hypoglycemic nke ọgwụ a na-atụle.
Nchikota ya na cimetidine na ihe ndi ozo nke sulfonylurea na - ebute nsogbu nke lactic acidosis.
Mmanya ndakọrịta
Mmanya na-a inụ ya na ọgwụ nwere ike ibute hypoglycemia na ọnọdụ disulfiram. Ya mere, n'oge ọgwụgwọ kwesịrị ịhapụ nchikota ha.
Mmanya na-a inụ ya na ọgwụ nwere ike ibute hypoglycemia na ọnọdụ disulfiram.
Analogs
Mwere ike dochie anya ọgwụ:
- Siofor;
- Metformin;
- Gluconorm;
- Metglib;
- Ike nke Metglib;
- Ndị Glucovans;
- Gluconorm Plus.
Ahịa ọgwụ na-ahapụ okwu
Erere ọgwụ.
Erere ọgwụ.
Ọnụahịa Glibomet
N'ime ụlọ ahịa ọgwụ na Russia, mbadamba mkpuchi nwere ọnụ n'etiti 330-360 rubles. maka kaadiboodu nke nwere pedi 4 nke ogwu 10 n’ime nke ọ bụla na ntuziaka maka ojiji.
Ọnọdụ nchekwa maka ọgwụ
Ọnọdụ kachasị mma: ebe akọrọ, ebe gbara ọchịchịrị nke ụmụaka anaghị enweta ya, ọnọdụ okpomọkụ ekwesịghị ịfe + 25 Celsius.
Bọchị mmebi
Ọ gafere ọnwa 36. Emela mbadamba mbubreyo.
Emeputa
Lọ ọrụ German "Berlin-Chemie Menarini Group / AG".
Nyocha nke Glibomet
Nadezhda Khovrina, 40 afọ, Moscow
Tupu dọkịta ekwuo ọgwụ a, m na-eji Glucofage. Ma, o nweghi uru obula diri ya. A ọgwụ ndị a ngwa ngwa ma dị ala belata shuga. Ekwenyere nke a site na nyocha.
Galina Guseva, gbara afọ 45, St. Petersburg
Anọwo m na-a theụ ọgwụ ahụ ogologo oge. Nsonaazụ ahụ na-adịgide Na nso nso a, m gara hụ dọkịta ka ọ chọpụta ma enwere ike ịjikọta ya na ọgwụ nje ndị ọzọ, ebe m nwere enyo nke helminthiasis. Dọkịta kwadoro nnabata ha n'otu oge. Ugbu a, enwere m ike ịrahụ ụra n'udo.
