Ọgwụ Liptonorm: ntuziaka maka ojiji

Liptonorm so na usoro cholesterol mepụta. Ọgwụ na-emetụta ọrụ nke ndị na-anabata LDL, si otú a belata ihe ize ndụ nke ịmalite ọrịa atherosclerosis na ọrịa nje ndị ọzọ. Ọnọdụ ndị o mepụtara na-enye gị ohere imebelata ịdị arọ, mana enweghị ike ịkpọ ọgwụ a ụzọ ọ ga-esi felata. Site n'enyemaka ya, ọ bụ naanị nsonaazụ a nwetara site na ọzụzụ na nri ka akwadoro. Dịka ngwaọrụ nnwere onwe, anaghị eji ọgwụ ahụ eme ihe, n'ihi na ọ naghị arụ ọrụ siri ike.

International Nonproprietary Aha

Atorvastatin

Liptonorm so na usoro cholesterol mepụta.

ATX

C10AA05

Ha weputara udi ya na ihe mebere ya

A na-emepụta ọgwụ ahụ n'ụdị siri ike. Na-anọchite anya otu ihe eji eme ihe otu ihe. Ihe dị n’ime ihe na-egosipụta mmetụta belata lipid bụ atorvastatin, a na-ejikwa ya n’ụdị nnu nke calcium. Mbadamba ụrọ ahụ nwere 10 mg ma ọ bụ 20 mg. Na mgbakwunye, a na-eji ọgwụ ndị ọzọ na-arụ ọrụ ndị ọzọ (ma ha kacha eji eme ihe iji nweta ụdị ọgwụ a chọrọ):

• kaboneti carbonate;
• microcrystalline cellulose;
• lactose;
• Ejima 80;
• hydroxypropyl cellulose;
• crosscarmellose;
• stereta magnesium.

A na-eji mbadamba ihe pụrụ iche kpuchie mbadamba nkume ndị ahụ, nke na-enyere aka nwayọ nwayọ nke ihe ndị nọ n'ọrụ. N'ihi nke a, a na-eji nwayọ belata ogo nke ọgwụ ike. Yabụ, ịkwesighi ịta ogwu ahụ, n'ihi na nke a ga - enye aka na nbịpụta oge nke ihe mejupụtara ya.

A na-eji mbadamba ihe pụrụ iche kpuchie mbadamba nkume ndị ahụ, nke na-enyere aka nwayọ nwayọ nke ihe ndị nọ n'ọrụ.

Omume ọgwụ

N'okpuru mmetụta nke ọgwụ ahụ, a na-achọpụta mbelata ọdịnaya nke lipoproteins dị ntakịrị, nke na-etinye aka na usoro nke ịgbanye plasta nwanyị cholesterol. Ha na-akpalite ọgba aghara nke sistem vaskụla: ha na-atụnye ụtụ n'icheba abụba n'ahụ mgbidi akwara, mmepe nke atherosclerosis, infarction myocardial, na ọrịa strok. N'ọnọdụ ka ukwuu, ịtalata oghere nke arịa ahụ, na-eduga na mgbochi nke ọbara ọgbụgba.

Site n'enyemaka nke ọgwụ a, ọ ga-ekwe omume izere mmepe nke nnukwu nsogbu, n'ihi na akụrụngwa na-arụ ọrụ na ihe mejupụtara ya na-enyere aka belata akwara dị na ahụ. Ọgwụ a bụ nke otu statins (iwetulata cholesterol ọbara).

Pharmacodynamics sitere na imebi usoro nke mmekorita nke HMG-CoA reductase, enzyme nke na-akwalite mgbanwe nke HMG-CoA n'ime mevalonic acid. A na - enweta nsonaazụ a chọrọ site na njikọta nke ụmụ irighiri ihe nke ihe na - arụ ọrụ na saịtị coenzyme A receptor, nke a na - ahụ maka njikọ ya na HMG-CoA reductase.

N'ọnọdụ ka ukwuu, ịtalata oghere nke arịa ahụ, na-eduga na mgbochi nke ọbara ọgbụgba.

A na - enweta nsonaazụ dị mkpa n'ihi mbelata nke ukwuu na mmepụta mevalonate, nke bụ ihe dị n’etiti usoro nke mmepụta cholesterol. N’ihi nke a, ọkwa cholesterol dị n’ime sel na-ebelata, nke na-enyere aka mee ka ọrụ nke ndị na-anabata LDL na mmebi metabolism nke cholesterol.

Ngwá ọrụ ọ bụghị naanị na-egosipụta mmetụta mmerụ ahụ, mana ọ na-enyekwa nchekwa nke akwara ọbara site na mmepe nke mmeghachi omume na-adịghị mma n'ihi mmetụta mgbochi na njikọ nke mkpụrụ ndụ endothelial. A na - enweta mmetụta a chọrọ site na igbochi mmepụta nke isoprenoids.

Na mgbakwunye, ọgwụ ahụ gosipụtara ihe ndị ọzọ: ọ na-eme ka ọnọdụ nke mgbidi dị n'ime nke arịa ọbara pụta, na-edozi ihe mejupụtara ọbara. Ọ na-egosipụta onwe ya dị ka ọgwụ antioxidant, antiproliferative. Enwere mmụba na ọkwa nke HDL, apolipoprotein A.

Uru Liptonorm bụ ike ya nwere ike ime ka ọkwa cholesterol dị na ndị ọrịa nwere ọrịa mkpụrụ ndụ ihe nketa.

Uru ọzọ nke Liptonorm bụ ikike ya nwere ime ka cholesterol dị n'etiti ndị ọrịa nwere ọrịa okike (hypercholesterolemia). Ọzọkwa, ọtụtụ ọgwụ ọgwụ na-egbusi ike enweghị ike ịnagide ọrụ a.

Mlọ ọgwụ

Ngwaọrụ ahụ na-adọkpụ mgbidi nke akụkụ ahụ digestive. Otutu atorvastatin na plasma ka edoziri mgbe nkeji 60-120 gachara. Nri na-emetụta mmata nke ihe a, agbanyeghị, ogo ịdị n’ọrụ ọ na-agbanwe agbanwe. Nke a pụtara na ọdịnaya LDL na-agbadata site na nha nha anya n ’iwere mbadamba Liptonorm n’elu afọ na nri.

Bioavailability nke ọgwụ dị ala ma dị 14%. A kọwara ihe omume a site na mmetụta acidic gburugburu na afọ na ọgwụ n'oge akụkụ mbụ na metabolization. A na-ekpebi ọkwa nke ịdịmma ya site na usoro onorvastatin. Indtinye protein na-edozi ọbara dị elu (98%). Ngbanwe nke isi ihe na-eme na imeju, ndi enzymes CYP3A4, CYP3A5 na CYP3A7 na-akwado ya. Nsonaazụ nke usoro a bụ ntọhapụ nke ogige na-egosipụta ọrụ ndọda.

Ngwaọrụ ahụ na-adọkpụ mgbidi nke akụkụ ahụ digestive.

A na - enweta mmetụta a chọrọ iji nweta oke ibu site na metabolites. Nsonaazụ nke a nwetara na ọgwụ Liptonorm na-anọ ogologo oge: site na awa 20 ruo 30 awa. Mgbe nke ahụ gasịrị, ọdịnaya nke atorvastatin na-ebelata. Usoro ndụ ọkara na-ewe awa iri na anọ. Ọzọkwa, isi ụzọ iwepu ihe na-arụ ọrụ n'ahụ ahụ bụ ihe ọleụ .ụ. Ma ọ bụ naanị obere ego ka ekpebiri na mmamịrị (ihe ruru 2%). O kwesiri iburu n’uche na ntinye nke atorvastatin n’ututu bu uzo ato n’ime elu karia nke anyasi.

Ihe ngosi maka ojiji

A na-atụ aro ka iji ngwaọrụ ahụ n'ọnọdụ ndị a:

1. Nnukwu mmụba na ọdịnaya nke lipoproteins dị ntakịrị.
2. Mmụba a na-achịkwaghị achịkwa nke ịkpa oke cholesterol n'ime ọbara (hypercholesterolemia), gụnyere ọnọdụ pathologies nke otu okike kpatara nsogbu mkpụrụ ndụ ihe nketa. N'okwu a, a na-atụ aro ịkọ ọgwụ a na ọgwụ ndị ọzọ, ka ihe inyeaka maka ịbelata ibu megide nri nke nri.

Mmụba a na-achịkwa na nchịkọta nke cholesterol n'ime ọbara bụ ihe na-egosi iji ọgwụ ahụ.

Ihe ngbanwe

Ejila ihe ndị a na-ekwu maka ya na mmeghachi omume na-adịghị mma maka mpaghara ọrụ ya ma ọ bụ ogige ndị ọzọ na ihe mejupụtara. Enwere ihe mgbochi iji ojiji n'ọnọdụ ọrụ imeju na akụrụ. Akụkụ akụkụ ndị a dị maka mgbanwe na mkpochapụ atorvastatin, yabụ ọ dị mkpa izere nrụgide dị egwu na ha.

Jiri nlezianya

Ikwu contraindications:

• ọrịa ọrịa imeju na-adịghị ala ala na enweghị ọnụnọ nnukwu ọrịa (akụkọ ihe mere eme);
• nsogbu metabolic na endocrine;
• mgbanwe na mmiri-electrolyte nguzozi;
• usoro septik;
• Ọnọdụ nkwenye siri ike nke siri ike nchịkwa;
• mmerụ ahụ
• arụmọrụ.

N'ihe banyere ọrịa metabolic, ị takingụ ọgwụ ahụ bụ contraindicated.

Edere Liptonorm maka ọrịa ọrịa imeju.

Ekwesịrị ịkpachara anya banyere Liptonorm na usoro septik.

Ọnọdụ ime mmụọ siri ike njikwa bụ ọgwụ sitere na iji ọgwụ a.

Gerywa ahụ bụ ihe mgbochi na ntinye aka nke Liptonorm.

Etu esi ewere Liptonorm?

Ọgwụgwọ bidoro na 10 mg kwa ụbọchị (ekwesịrị ị thisụ ọgwụ a otu ugboro). Mgbe ahụ, ego a kapịrị ọnụ ka abawanye na-eburu n'uche ọkwa cholesterol dị n'ọbara. Ekwesịrị ịme mgbanwe mgbanwe na izu anọ kwa izu. Uru kachasị dị kwa ụbọchị nke atorvastatin bụ 80 mg. Ọkwa a bụ ihe ụkpụrụ maka hypercholesterolemia nke ọrịa na-ebute ọrịa.

Na-arịa ọrịa shuga

Jiri ogwu jiri nlezianya mee, agbanyeghị, a kọpụtaghị usoro ọgwụgwọ ahụ na nke a. Enwere ike iji usoro ọgwụgwọ ọgwụgwọ (10 mg kwa ụbọchị).

Nsonaazụ

Ngwá ọrụ ahụ na-akpalite ọdịdị nke nnukwu mmeghachi omume na-adịghị mma. Ọzọkwa, enwere ihe ize ndụ nke ịdị na akụkụ nke sistemụ dị iche iche.

Na ọrịa shuga mellitus, were ọgwụ lezie anya.

Site na anụ ahụ anụ ahụ

Hydration nke mucous ezughị ezu, ọrịa anya umengwụ, nkwarụ ntị, ọbara ọgbụgba, ọgba aghara nke ebe obibi, ụtọ (mgbanwe ma ọ bụ mfu kpamkpam).

Site na anụ ahụ na akwara

Ọnọdụ ọgbụgba, ọrịa ogbu na nkwonkwo, tendosynovitis na ọrịa ndị ọzọ na-akpata ọrịa, yana mmerụ ahụ sitere na mmalite dị iche iche (ọrịa ogbu na nkwonkwo, myalgia, wdg), nkwonkwo nkwonkwo, ụba ụda anụ ahụ dị nro, myopathy.

Ọkpụkpụ afọ

Mgbu na afọ, obi mgbawa, ọgbụgbọ, akwa ma ọ bụ afọ ntachi, belatara ma ọ bụ nwekwuo agụụ, ọrịa na-akpata ọrịa dị iche iche, ọbara ọgbụgba, ọnya cholestatic, ịba ọcha n'anya na hepatic colic, vomiting.

Ahụhụ Hematopoietic

Ọnọdụ ọrịa dịgasị iche iche tinyere mgbanwe n'ọdịdị ọbara: anaemia, thrombocytopenia, wdg.

Mgbe ị na-a theụ ọgwụ ahụ, ogbu na nkwonkwo nwere ike ibute.

Ọbara a na-ahụ anya bụ mmetụta dị n'akụkụ Liptonorm.

Liptonorm nwere ike ibute ọgbụgbọ, vomiting.

Mgbe ị na-ewere Liptonorm, obi mgbawa nwere ike ime.

Enwere ike ijikọta mmebi ntị na ị Liụ Liptonorm.

Mgbe ị na-ewere Lopirel, mgbu n'ime afọ nwere ike apụta.

Sistemụ akwara Central

Mwepu n’otutu ura, onya isi, adighi ike n’iru, ura, paresthesia na neuropathy, onodu ncheta (usoro nbughari), ita mba, nkpuru obi gi.

Site na sistem iku ume

Ọtụtụ mgbe, kwuru banyere mmepe nke rhinitis, bronchitis. Oria na-ejikarị oria afọ ọsịsa, ụkwara ume ọkụ.

Site na usoro mkpụrụ ndụ ihe nketa

Ọrịa urogenital tract, ọzịza, ọbara ọgbụgba, nephritis, arụrụala arụ ọrụ (n'ime ụmụ nwoke), urination nke ọma.

Site na usoro akwara obi

Mgbu n’obi, mmụba obi, oke isi ọwụwa, mbelata ma ọ bụ mgbali elu, yana mbufụt nke arịa ọbara.

Liptonorm nwere ike ime ka iro ụra.

Dizziness bụ mmetụta dị n'akụkụ Liptonorm.

Ka ị na-a Liụ Liptonorm, ncheta ihe ga-ekwe omume.

Ahụ́ mkpọnwụ na-emegharị ahụ́ bụ otu n’ime nsogbu ndị ọgwụ dị.

Inweta Liptonorm nwere ike ibute rhinitis.

N'ime ụmụ nwoke na-ewere Liptonorm, a na-ahụta mmerụ nwoke na nwanyị.

Mmetụta ọzọ ị ofụ ọgwụ bụ nhụpụta mgbu n'ime obi.

Ahụhụ

Udiri ihe ngosiputa nke mmeghachi omume ojoo na-eme: ihe mgbawa, itching, mbuze, ume iku ume n'ihi angioedema, ịmụba ka ọkụ, erythema, yana ịhapụ oke nke exudate.

Mmetụta ikike ịchịkwa usoro

Enweghị ihe omuma banyere ikpe mgbe ị na-ewere Liptonorm na-emetụta ọnọdụ nke ahụ n'ụzọ na-adịghị mma mgbe ị na-anya ụgbọ ala.

Ntụziaka pụrụ iche

N'oge usoro ọgwụgwọ, onye na-ahụ maka ọrụ na-agbanwe ọnọdụ nke imeju. Ọ dị mkpa inyocha ọrụ nke anụ ahụ tupu ịmalite ọgwụgwọ, n'oge na mgbe ọ gachara. Ekwesiri iburu n'uche na a na-ahụ mgbanwe na ọrụ nke enzymes imeju na ọnwa atọ mbụ mgbe mmalite nke usoro ahụ.

Ọ bụrụ na-egosi na mgbaàmà nke nnukwu nsogbu na ọrịa nke akwara, akwara ma ọ bụ akụrụ, a na-akwụsị ịgwọ ọrịa.

Ọ bụrụ na ihe mgbaàmà nke nnukwu nsogbu na-apụta na ọrịa nke imeju ma ọ bụ akụrụ, ọgwụgwọ na-akwụsị.

Jiri na agadi

A na-ahapụ ngwá ọrụ ka ọ rụọ ọrụ, a naghị arụ ọrụ mgbanwe otu oge.

Inye umuaka

Maka ndị ọrịa na-erubeghị afọ 18, a naghị atụ aro ọgwụ ahụ.

Jiri n'oge ime na lactation

Amachibidoro ọgwụ a iji mee ihe n’oge mmegharị ahụ na n’oge a na-enye nwa ara, n’ihi na ekwenyeghị na nsonaazụ ọma ya n’ọnọdụ ndị a.

Ngwa maka ọrụ ezughi oke ọrụ

Edeghi ya ka ọghara aru a.

Jiri maka ọrụ imeju na-arụ ọrụ

Site n'ọrịa cirrhosis, usoro ọgwụ dị n'ime ọbara na-abawanye ọtụtụ oge. Maka nke a, anaghị eji ya. Enweghi ike iji ya maka imeju imeju (ogo A na B dabere na usoro nke Child-Pugh), mmụba na mkpokọta nke transperat hepatic nke etiology na-amaghị na ọrịa ndị ọzọ nke akụkụ a na mpaghara ọrụ, gụnyere ndị na-efe efe na-efe efe. Maka nsogbu ịba ọcha n'anya, idozi ọ̀gaghị adị mkpa.

Site n'ọrịa cirrhosis, usoro ọgwụ dị n'ime ọbara na-abawanye ọtụtụ oge.

Dodoụbiga ya ókè

Site na mmụba nke nsonaazụ na-emegide ihe ndabere maka ịba ụba nke ọgwụ ahụ, a na-eme ọgwụgwọ Symptomatic, a na-eme gastric lavage, sorbents edere. N'oge nke a, ịba ọcha n'anya enweghị ike iji ya mee ihe. Ọ dị mkpa iji nọgide na-arụ ọrụ nke anụ ahụ.

Mmekọrịta na ọgwụ ndị ọzọ

Edere ọgwụ ọgwụ a na-ejikọ ya na cyclosporins, Erythromycin, Clarithromycin, ọgwụ antifungal, immunosuppressants, ma ọ bụrụ na uru ya karịrị ihe mmerụ ahụ. N'iji oge nke atorvastatin na ihe ndị a, a na-achọpụta mmụba nke mkpokọta nke mbụ. Ojiji nke protein inhibitors na ọgwụgwọ na-enye otu mmetụta.

Igonweta Digoxin na-abawanye site na 20%. Atorvastatin na - emekwa ụfọdụ ọgwụ mgbochi ọrịa n’ọnụ n’otu ụzọ ahụ.

Site n'otu oge iji ọgwụ a na Colestipol, enwere mmụba dị ukwuu na ọkwa nke ọgwụgwọ.

Warfarin nwere ike ibelata oge prothrombin nwa oge. Mgbe izu abụọ gasị, ihe ngosi a na - ezi.

Site n'otu oge iji ọgwụ a na Colestipol, enwere mmụba dị ukwuu na ọkwa nke ọgwụgwọ.

Mmanya ndakọrịta

Enwere ike iji ọgwụ ahụ wepụ ihe ngosipụta nke mgbaàmà ndọrọ ego, mana n'otu oge ahụ na mmanya nwere mmanya na-egbu egbu anaghị a itụ ya.

Analogs

Dochie ndị dị irè:

• Torvacard
• Atorvastatin;
• Liprimar.

Okwu Liptonorma Ezumike Ezumike

Ogwu bu ogwu.

Enwere m ike ịzụta na ndenye ọgwụ?

Enweghị ụdị dị otú ahụ.

Ọnụ ọnụ Liptonorm

Ọnụ ego ya na Mọsko bụ 238 rubles. Na mpaghara ndị ọzọ, ọnụahịa ahụ nwere ike ịdị iche iche.

Ọnọdụ nchekwa maka ọgwụ

Ọnọdụ ikuku na-anabata - adịghị elu karịa + 25 Celsius С.

Torvacard bụ analogue nke ọgwụ Liptonorm.

A na-ahụ Atorvastatin ka ọ bụ analog nke ọgwụ Liptonorm.

A na-ahụta Liprimar bụ analogue nke ọgwụ Liptonorm.

Bọchị mmebi

Oge nke ị drugụ ọgwụ na-enweghị ihe onwunwe bụ afọ abụọ site na ụbọchị emepụtara.

Onye na-eme Liptonorm

Onye na-ere ọgwụ, Russia.

Nyocha na-efufu ibu banyere Liptonorm

Valeria, onye gbara afọ 43, Simferopol.

A na-eji nwayọ nwayọ nwayọ nwayọ na ndụ, yabụ bukwara ibu. Amụtara m na ọgwụ a na - enyere aka idebe onwe m n ’ụdị, ana m azụtara ya ozugbo. Na-emegide nzụlite nri dị mma na ibu dị obere, ahụghị m nsonaazụ a, ikekwe nke a bụ n'ihi eziokwu ahụ bụ na usoro ndị m ji ezuru m, ọ dịkwa anya ịtụgharị ọgwụ.

Anna, 35 afọ, Krasnoyarsk.

Ezi usọbọ. Enwere m oke ibu (+ 20 n'arọ mgbe ịtụrụ ime). Anọwo m na-a drugụ ọgwụ a ogologo oge, nsonaazụ pụtara nke ọma: ibu ahụ akwụsịla itolite, were nwayọ mana ọ ga-agbada. Mmega ahụ dị ntakịrị n'ihi enweghị oge, ana m anwa ịgbaso nri kwesịrị ekwesị.O jikwa ọgwụ ọgwụgwọ homeopathic ma gwọ ọgwụ ọdịnala ruo mgbe ọ chọta ụzọ ka mma.

Ndi dibia nyocha

Alekhine, E. B., dọkịta na-awa ahụ, 38 afọ, Krasnodar.

Ngwá ọrụ arụmọrụ na-adịghị mma. Mgbake zuru oke anaghị enye, mana ọ na - arụ ọrụ nke ọma dịka aka inyeaka, na - eme ka usoro mweghachi nke arịa ọbara dị.

Nyocha banyere ọrịa mamịrị

Olga, 35 afọ, Samara.

N'azụ ọrịa shuga, ọtụtụ nsogbu pụtara, gụnyere oke ibu. Amaghị m ihe kpatara nke a, mana mụ onwe m ọgwụ a abaghị uru ma ọ bụrụ na ebumnuche bụ ịbelata oke. Ọ na-eme ike. Nsonaazụ nke Liptonorm dịka ụzọ isi kwado ọrụ nke usoro akwara vootu dị elu. Symptomsfọdụ mgbaama ahụ apụtaghị, ahụ efe bịara.

Gennady, 39 afọ, Stary Oskol.

O were ogwu ahu belata cholesterol ọbara. N'oge ọgwụgwọ, mmetụta ahụ nwere mmetụta. Mgbe ọ kwụsịrị ị takingụ ọgwụ, nsogbu ahụike niile lọghachiri.