Thrombomag - ọgwụ nke otu NSAID, gosipụtara mmetụta antiplatelet. Site na ya, a na-ebelata ihe ize ndụ nke ibute ọrịa ndị a na-ebute site na ịmepụta mkpụkọ ọbara. Ọzọkwa, ọgwụ gosipụtara ihe ndị ọzọ, ọkachasị, na-enyere aka iwepu mbufụt.
International Nonproprietary Aha
Acetylsalicylic acid + Magnesium hydroxide
Thrombomag - ọgwụ nke otu NSAID, gosipụtara mmetụta antiplatelet.
ATX
B01AC30
Ha weputara udi ya na ihe mebere ya
Enwere ike ịzụta ọgwụ ahụ naanị n'ụdị ọgwụ. Ọ na-anọchite anya otu ngwaọrụ eji eme ihe abụọ. A na-egosipụta njiko ihe ngosi maka ọrụ dị iche iche. Dị ka ihe ndị na-arụ ọrụ bụ:
- acetylsalicylic acid;
- magnesium hydroxide.
Mbadamba nwere oke nke ihe ndi a. Iji maa atụ, ọgwụ ASA bụ 0.75 na 0.15 g. Magnesium chloride dị na mbadamba 1 na ọnụọgụ 15.2 na 30.39 mg. Mbadamba ụrọ ahụ kpuchie ya, mana n'adịghị ka analogues, a na-ahapụ ya ka ọ ghee ya tupu iwere. Na mgbakwunye, ihe dị na Thrombomag gụnyere ihe ndị na-anaghị egosipụta nchịkọta mgbochi na ọrụ mgbochi:
- ọka ọka;
- nduku;
- microcrystalline cellulose;
- citric acid;
- stereta magnesium.
A na-enye ọgwụ ahụ na ngwugwu (3 na PC 10). Nke ọ bụla n'ime ha nwere mbadamba 10.
Enwere ike ịzụta ọgwụ ahụ naanị n'ụdị ọgwụ.
Omume ọgwụ
Ebumnuche ebumnuche ọgwụ ahụ bụ igbochi mmepụta nke thromboxane A2. A rụpụtara nsonaazụ a site na igbochi njikọ nke COX-1 isoenzymes. Agbanyeghị, enwere mbelata nke nrụpụta nke renal prostaglandins. N'ihi nke a, ngosipụta na-adịghị mma nke mbufụt jizi nwayọ pụọ ma ọ bụ ogo ha na-ebelata nke ukwuu.
A na-ekesasị ASA n'ime ahụ niile, na-enye ọ bụghị naanị ọgwụ antithrombotic, mmetụta mgbochi mkpali, kamakwa na-enye mmetụta antipyretic. Ihe ikpeazụ nke ihe onwunwe bụ n'ihi mmetụta na-eto eto na hypothalamus na etiti nke thermoregulation akpan akpan. Mgbe ị takingụ ọgwụ ahụ, acetylsalicylic acid bụ metabolized, n'ihi nke a, a na-ahapụ salicylates. Ihe ndị a na-enyere aka belata algogenic nke bradykinin, n'ihi nke a na-ebelata ogo ihe mgbu.
N'ihi ọnụọgụ dị ukwuu nke ejiri mara ASA, a na-ewebata ihe ahụ n'ime mejupụtara ọtụtụ ọgwụ. Nsonaazụ antiplatelet ya bụ n'ihi ike ọ bụghị naanị igbochi nchịkọta platelet, kamakwa iji belata ọnụego njikọta ha na ibe ha. ASA na-emetụta akpukpọ sel sel ọbara, ebe nsogbu ha na-ebelata. N'ihi ya, a na-eme ka usoro nke mkpụrụ ndụ ọbara uhie site n'ihe ndị mejupụtara ya, n'ihi nke ama ama akọwapụtara ihe ndị metụtara ịmịnye ọbara, mmiri ya na-ebelata.
Mmetụta ọgwụ a na-abawanye ọbara ọgbụgba. Ngwongwo ndi ozo nke ASA bu ikpochapu obara oria. A na-agakọ mmetụta niile nke ihe a nyere. Yabụ, ihe ndị na - egbochi ihe nchịkọta na - eme ka nnabata nke prostaglandins pụta, mana enwere ụdị ọrụ dị iche. Nke a na-ebelata ọkwa nke calcium ionized, nke na-enyere aka belata ike nchịkọta platelet.
Akụ nke nchịkọta nke ASA bụ mkpochapu nke mkpụkọ ọbara.
Mwepu nke ọgwụ ahụ bụ mkpochapụ nke njikọta antithrombotic prostaglandins. A na-enye nsonaazụ a mgbe ewere ọgwụ ahụ na nnukwu ọgwụ. Nsonaazụ bu ihe ozo nke uto a choro. Maka nke a, a ga-agbaso kwa ụbọchị nke onye nrụpụtara tụrụ aro (ọ dịghị ihe karịrị 325 mg).
Akụkụ ọzọ na-arụ ọrụ na mejupụtara ahụ na-egosipụta akụrụngwa antacid na laxative. N'ihi ya, a na-ebelata ohere ihe ọghọm n’oge ọgwụgwọ belata, n’ihi na ihe a na-eme ka mmetụta ASA dị mkpụmkpụ nke eriri afọ. Mgbe ị theụsịrị ọgwụ ahụ, magnesium hydrochloride na-etinye ihe ọ gastụ withụ na mmiri ọ gastụ gastụ gastric, nke na-eduga na ịkpụpụta magnesium chloride.
Mgbe ihe a ruru eriri afọ, a na-egosipụta mmetụta ya ga-anyụ anyụ. Nke a bụ n'ihi enweghị ike ịgbari na gburugburu ebe obibi. Magnesium chloride na-akpali peristalsis nke anụ ahụ. Ngwongwo ozo bu ikike nke ijiri acid bile. Anụ ahụ na-eripịa ihe a, nke na-eso eme ya ogologo.
Mgbe ị theụsịrị ọgwụ ahụ, magnesium hydrochloride na-etinye ihe ọ gastụ withụ na mmiri ọ gastụ gastụ gastric, nke na-eduga na ịkpụpụta magnesium chloride.
Mlọ ọgwụ
A na-atụ aro ka ị theụ ọgwụ ahụ iche na nri, n'ihi na nnabata nke ihe ndị na-arụ ọrụ nwere ike ibelata, nke ga-emetụta ọnụego ntọhapụ ha. A na-etinye ihe ndị dị na ọgwụ ahụ n'otu ntabi anya, na zuru ezu. Usoro mgbanwe nke acetylsalicylic acid bu otutu uzo. Nke mbu, a ghaputara salicylic acid, nke emesiri metabolized site na mpụta otutu mmanu: phenyl salicylate, glucuronide salicylate, salicyluric acid.
Mmetụta kachasị elu nke ọgwụ ahụ pụtara nkeji 10-20 mgbe ị .ụ ọgwụ. Distributiongbasa oke n'ahụ niile bụ n'ihi na ọ jikọtara ya na protein protein. Agbanyeghị, usoro a dabere na usoro nke ọgwụ ASA: ego buru ibu nke ọgwụ a na-a ,ụ, ihe ka njọ molekulụ nke ihe ahụ si kee protein protein.
A na-ewepụ ihe ndị nọ n'ọrụ n'ime ọbara ngwa ngwa - n'ime nkeji iri abụọ, metabolites na-egbu oge maka ogologo oge. ASA na-ahapụ ahụ kpamkpam mgbe ụbọchị 1-3 gasịrị. Ọ bụ akụrụ na-ahụ maka usoro iwepu ihe ndị bụ isi. Akụkụ nke abụọ na-arụ ọrụ (magnesium hydrochloride) anaghị emetụta bioavailability nke acetylsalicylic acid.
A na-atụ aro ị theụ ọgwụ ahụ iche na nri.
Ihe ngosi maka ojiji
Edere usọbọ a maka ọnọdụ ọrịa a:
- mgbochi mbụ nke ọrịa dị iche iche nke CVD: embolism na thrombosis nke veins na akwara, ọdịda obi, ma ọ bụrụ na enwere ihe ndị dị ize ndụ: ọrịa shuga, ọbara mgbali elu, àgwà ọjọọ, dị ka ị smokingụ sịga ma ọ bụ ị alcoholụbiga mmanya ókè;
- angina pectoris nke uwa anaghi agbanwe agbanwe;
- ihe mgbochi nke abụọ nke infarction myocardial;
- igbochi nsogbu site na ịwa ahụ, ọghọm nke nke a na-abawanye mgbe akwara akwara akwara ịwa grafting, coronary angioplasty.
Ọ ga - enyere aka na ọbara mgbali elu?
Ọgwụ a na-a questionụ na-eme ka mbelata ọbara mgbali elu, mana n'ọtụtụ mmetụta a gosipụtara onwe ya mgbe ị theụ ọgwụ ahụ tupu ị lakpuo ụra. Ekwesiri iburu n'uche na n'okpuru nduzi nke Thrombomag, nrụgide nwere ike ịdalata na nkatọ. Maka nke a, ekwesighi iji ya mgbe ị na-a drugsụ ọgwụ mgbochi mmiri.
Ihe ngbanwe
Ọgwụ nwere ọtụtụ mgbochi na nhọpụta:
- mmebi nke usoro iku ume n'oge ọgwụgwọ na acetylsalicylic acid;
- mmeghachi omume na-adịghị mma nke njirimara mmadụ na ntinye nke ASA na ihe ndị ọzọ na mejupụtara ahụ;
- setịpụrụ ọrịa: ụkwara ume ọkụ imi, imi mkpọchi, ịmachi acetylsalicylic acid, n'ọnọdụ a, ihe ọghọm nke iku ume na-abawanye;
- ọbara ọgbụgba na eriri afọ;
- ọbara ọgbụgba;
- mmepe nke mbuze na ihe owuwu nke mgbidi olulu;
- nnukwu nsogbu ọbara ọgbụgba (megide ndabere nke thrombocytopenia, ụkọ vitamin K, wdg);
- Enyocha glucose-6-phosphate.
Jiri nlezianya
E nwere ọnụọgụ dị ukwuu nke contraindications nke ọ nwere ike iji ọgwụ, mana ịkpachara anya chọrọ:
- hyperuricemia
- gout
- sepsis
- na mbụ chọpụtara ọnya afọ na duodenal ọnya afọ;
- ụdị nke imeju na akụrụ arụrụala;
- ụkwara ume ọkụ;
- ọrịa nke usoro iku ume;
- oge tupu;
- ihe nfụkasị ahụ.
Etu esi ewere thrombomag?
N ’oge ụfọdụ, a na-edenye ọ̀tụ̀tụ̀ na-akari ihe mbadamba 1-2 kwa ụbọchị. A na-ewere ọgwụ ahụ otu ugboro. Usoro ọgwụgwọ nwere ike ịdị iche. Dịka ọmụmaatụ, iji gbochie CCC pathologies, etinyere 150 mg kwa ụbọchị, mgbe ahụ belata ego a site ugboro abụọ. N'ọnọdụ ndị ọzọ, a na-ahụta ka o zuru oke iji were mbadamba ọgwụ 1 mee ihe ASA (75 ma ọ bụ 150 mg), nke dabere na ogo ọrịa ahụ.
Site n'ụdị dị ntakịrị nke akụrụ na ọrịa imeju, a ga-eji nlezianya mee ọgwụ ahụ.
Na-arịa ọrịa shuga
A kwadoro ọgwụ ahụ maka iji ya, a naghị emezigharị ọgwụ, mana ekwesịrị inyocha onye ọrịa ahụ.
Mmetụta akụkụ nke Thrombomagus
Mmeghachi omume na-adịghị mma n'oge ọgwụgwọ na onye nnọchianya a abụghị ihe a na-ahụkarị karịa Acetylsalicylic acid, n'ihi na ego nke ihe ndị na-arụ ọrụ dị obere, mmetụta nke mbadamba ahụ na-adịkwa nro karị. Nsonaazụ na-emekarị:
- isi ọwụwa
- ọbara ọgbụgba
- ọla;
- ọgbụgbọ na ọgbụgbọ
- obi mgbawa.
Ọ na - abụkarị ndị a na - ahụkarị ụdị ihe ịrịba ama a:
- adịghị ike n'ozuzu;
- Dizziness
- ọnụnụ ntị, tinyere tinnitus oge niile;
- ọbara ọgbụgba;
- ndakpọ nke usoro hematopoietic, nke gosipụtara site na anaemia, thrombocytopenia, wdg.
- ọnya afọ na-egbu mgbu, nke n'ọtụtụ oge bu mgbu n'ime afọ;
- ọnụ;
- ngosipụta dị iche iche nke allergies: ọzịza nke akụkụ okuku ume, itching, ihe mgbu, hyperemia, rhinitis;
- arụ ọrụ ezumike.
Mmetụta ikike ịchịkwa usoro
Kwọ ụgbọala abụghị ihe mgbochi. Agbanyeghị, enyere nsogbu ahụ siri ike ịmalite n'oge ọgwụgwọ, ekwesịrị ịkpachara anya.
Ntụziaka pụrụ iche
Mgbe ị na-edepụta ọgwụ ajuju tupu ịwa ahụ, a ga-echetarịrị na ihe mgbochi nke ọgwụ ahụ nwere ike ime n'ime ụbọchị 3 site na mbadamba ụrọ ikpeazụ.
N'oge a na-elekọta ndị ọrịa nwere nsogbu gbasara akụrụngwa, ọ dị mkpa ileba anya mgbe niile ihe ndị na-egosi na steeti akụkụ a.
N ’usoro ọgwụgwọ mbụ na nke ikpe-azụ, ekwesịrị ime nyocha nke ọbara.
Jiri na agadi
N’ime ndị ọrịa n’otu a, ọghọm dị n’ọbara na-abawanye ma ọ bụrụ na e were ntakịrị nke Trobomag. Iji zere nsogbu, a na-enyocha ọbara na imeju na-egosi ihe niile.
N’ime ndị ọrịa agadi, nsogbu ọbara ọgbụgba na-abawanye ma ọ bụrụ na ewere ntakịrị nke Trobomag.
Inye umuaka
Ejighi ya.
Jiri n'oge ime na lactation
Edeghị ọgwụ ahụ n'oge mmegharị ahụ, mmachi ahụ metụtara naanị m na III trimesters. Ihe mgbochi dị otú a bụ n'ihi ihe egwu nke ibute ọrịa. A ma ama na mmechi mmechi akwara ozi nke nwa ebu n'afọ na-achọpụta. Ọrịa obi nwatakịrị nwere ike ịmalite. N’ime ọnwa nke abụọ, a na-ahapụ ya ka ọ theụ ọgwụ a n’adịghị oke 150mg kwa ụbọchị.
N’oge ị na-a breastụ ara, a naghị enye ọgwụ a na-a questionụ a .ụ.
Ngwa maka ọrụ ezughi oke ọrụ
Ekwesịrị ịkpachara anya, ebe ọ bụ na magnesium hydrochloride nwere ike ịbanye na plasma ọbara. Na nke a, mmetụta nsị nke ihe ahụ na-abawanye. A na-egosipụta usoro a site na nkụda mmụọ nke usoro akwara ozi.
Na ọdịda akụrụngwa siri ike, a naghị eji ọgwụ ahụ eme ihe. N'okwu a, ị kwesịrị ilekwasị anya n'ihe ngosipụta nke creatinine (ihe na-erughị 30 ml kwa nkeji).
Mbibi imeju bụ contraindication maka ị takingụ ọgwụ.
Jiri maka ọrụ imeju na-arụ ọrụ
Ọ nwere ajọ mmerụ ahụ na - egbochi ọgwụ a.
Thrombomag overdose
A na - eme ka nsonaazụ nke ọtụtụ nsonaazụ ndị a kọwara n'elu. Ọ bụrụ na ewere nnukwu doses, ihe ịrịba ama nke ụdị ọrịa dị oke egwu na-apụta. Ọrịa
- ahụ ọkụ
- hyperventilation nke ngụgụ;
- hypoglycemia;
- alkalosis;
- ketoacidosis;
- oke mmebi nke akwara na akụkụ iku ume.
N'okwu a, usoro ọgwụgwọ gụnyere mkpa ọ dị lavage gastric. A na-atụ aro onye ọrịa ahụ ka ọ nwee ọgwụ mgbapụta n'ọtụtụ, hemodialysis, alkaline diuresis ka etinyere ya. A na - eme ihe iji weghachite nguzo mmiri-electrolyte. N'ihe banyere oke ịdoụ ọgwụ ọ ,ụ ,ụ, a na-aga ụlọ ọgwụ n'ụlọ ọgwụ.
N'ihe banyere oke ị ,ụbiga mmanya ókè, ọgwụgwọ metụtara ọgwụ mgbu.
Mmekọrịta na ọgwụ ndị ọzọ
A na - eme ka mmetụta nke methotrexate, valproic acid dịkwuo mma.
Ọtụtụ ọgwụ na ihe dị iche iche amarala, na n'otu oge nchịkwa nke mmeghachi omume ọjọọ na-etolite:
- ịkọ nkọ;
- NSAIDs;
- Insulin
- ọgwụ hypoglycemic;
- antiplatelet, anticoagulant na ndị nnọchi thrombolytic;
- sulfonamides;
- Digoxin;
- lithium;
- ethanol.
A na-ebelata ogo arụmọrụ nke ASA n'okpuru nduzi nke ọtụtụ ọgwụ na ihe: GCS maka ojiji sistemu, Ibuprofen, ọgwụ antacids ndị ọzọ, nke nwere magnesium ma ọ bụ aluminom hydroxide.
A na - eme ka mmetụta nke Methotrexate dị mma mgbe ejiri ya na Thrombomag.
Mmanya ndakọrịta
Ekwesịrị iji nlezianya mee ihe n'oge ọgwụgwọ na Thrombomagum, ebe ị na-a drinksụ mmanya nwere mmanya.
Analogs
Mkpụrụ ọgwụ ndị a ga-eji kama ọgwụ a na-atụle:
- Cardiomagnyl;
- Phasostable;
- Thrombital;
- Clopidogrel Plus.
Ahịa ọgwụ na-ahapụ okwu
Ogwu bu otu ogwu eji eme ogwu ogwu.
Enwere m ike ịzụta na ndenye ọgwụ?
Enwere ohere dị otú ahụ.
Ọnụahịa
Ọnụ ego ahụ dịgasị site na 100 ruo 200 rubles.
Ọnọdụ nchekwa maka ọgwụ
Na-ekwenye ọnọdụ okpomọkụ - ọ dịghị ihe karịrị + 25 Celsius С.
Bọchị mmebi
Okwesiri iji ngwaahịa ahụ afọ 2 site na ụbọchị ahapụ.
Emeputa
Hemofarm, Russia.
Nyocha
Veronika, afọ 33, St. Petersburg.
Ezigbo ọgwụ. Nwee mgbe a wasịrị ya ahụ. Nsonaazụ, belụsọ maka mmeghachi omume anụ ahụ na ọkwa mbụ. N'ihi Thrombomag, enweghị nsogbu ọ bụla, nke dị mkpa, n'ihi na ọbara m dị oke nnukwu.
Elena, 42 afọ, Alupka.
Iji ọbara mgbali elu, ọ dị mkpa iji chịkwaa oke nke ọgwụ. Ọ bụrụ na i jiri ya na-enweghị nchịkwa, ọbara mgbali nwere ike ịdalata na njedebe dị oke mkpa.Enwere m okwu: echefuru m ị theụ ọgwụ n'oge, mgbe ahụ ka m chetara ma itụọ ya ozugbo, mana n'oge na-adịghị anya oge ị forụ ọgwụ ọzọ ga-abịa. Eleghị m nke a anya ma mechie nnabata ahụ. N’ihi nke a, ha amachapụghị amịcha, nnukwu mgbada dara.