Accupro bụ ọgwụ ọgwụ ike ịgwọ maka nkụchi obi na iwetulata mgbali ọbara. O nwere mmetụta metabolic, cardio- na nephroprotective, nke nwere mmetụta bara uru na sistem. Ọgwụ ahụ na-egbochi ntụgharị nke ogige ndị nwere akụrụngwa vasoconstrictor. Mmetụta ya na-erute na plasma na enzymes anụ ahụ, na-enye mmetụta buru ibu.
International Nonproprietary Aha
Aha Latin nke ọgwụ: Accupro. INN: Quinapril.
ATX
Ọgwụ antihypertensive, ACE inhibitor. Koodu ATX: C09A A06.
Accupro bụ ọgwụ ọgwụ ike ịgwọ maka nkụchi obi na iwetulata mgbali ọbara.
Ha weputara udi ya na ihe mebere ya
Odikwa n'ụdị agba, triangular ma ọ bụ oval, mbadamba ihe na-acha ọcha ma ọ bụ ọbara ọbara. Otu mbadamba 1 nwere 5, 10, 20 ma ọ bụ 40 mg nke ihe na - arụ ọrụ - quinapril n'ụdị hydrochloride, yana ndị nwere ọgwụ. Mpempe kaadiboodu nwere blisters 3 ma ọ bụ 5, nke ọ bụla nwere mbadamba 6 ma ọ bụ 10.
Omume ọgwụ
Ọgwụ nzuzu nke na - egbochi ọrụ enzyme nke angiotensin, na ntinye nke angiotensin nke m na - agbanwe. Nke ikpeazụ bụ akụrụngwa endogenous na-eme ka ọbara mgbali elu na-arụ ọrụ. Mbelata na secretion nke ogige a na - eme ka mgbakwunye sodium excretion na oge na - egbu oge n'ime ahụ, nke na - ebelata nguzogide arịa arịa ma na - ebelata ọbara mgbali elu. Site n'iji ya eme ihe oge nile, ọ na - eji nwayọ nwayọ nwayọ na - eme ka uru akwara obi na akwara ọbara pụta, nke na - ebido na mbido ọbara mgbali elu.
Mlọ ọgwụ
Mgbe nchịkwa ọnụ gachara, etinyere mkpokọta quinapril na ọbara n'ime nkeji 60-90. Ọ dịkarịa ala 55% nke ọgwụ na-etinye.
N'okpuru ọrụ nke enzymes imeju, a na-eme ka ihe na-arụ ọrụ sie ike na quinaprilat, nke bụ ihe mgbochi ACE dị ike. Ya sistemu bioavailability dị 35%.
Ihe dị n’ime ya na metabolites ya abanyeghị na mgbochi ụbụrụ-ọbara ma sachapụ ya site na akụrụ. N'ime ndị ọrịa nwere nsogbu gbasara akụrụngwa, iwepu ọkara ndụ na-abawanye site na mbelata nwebisi creatinine.
Ihe ngosi maka ojiji
Edere ọgwụ ahụ maka ọgwụgwọ ọbara mgbali elu akwara na nkụchi obi na-adịghị ala ala.
Edere ọgwụ maka ọgwụgwọ ọbara mgbali elu.
Ihe ngbanwe
Ihe ogwu ahu bu nke anakpo onodu oria na onodu ndia:
- hypersensitivity na akụkụ ọ bụla;
- akụkọ banyere ọrịa angioedema n'ihi ọgwụgwọ mbụ ya na ọgwụ antihypertensive ma ọ bụ ketara eketa na / ma ọ bụ ọrịa nfụkasị ọrịa;
- enweghị lactose, glucose-galactose malabsorption.
Jiri nlezianya
Eji ya jiri nlezianya mee ka ọnụnọ nke ọrịa na ọnọdụ dị otú a:
- hypotension hypotension, ọkachasị ndị ọrịa bụ ndị buterela diuretics ma soro nri nwere obere nnu;
- nnukwu ọrịa akpataworo site na dysfunction dysfunction nke akwara obi;
- ọrịa shuga mellitus;
- akụrụ ma ọ bụ imeju akwara;
- autoimmune connective anụ ahụ;
- mkpụkọ ụkọ;
- hyperkalemia
- belata n'ọbara ọbara.
Na mbido ọgwụgwọ, a na-atụ aro iji ọgwụ a dabere na nyochaa njikwa ọbara.
Uzo esi ewere Accupro
Edebere ọkachamara na oge usoro ya na usoro ahụ, na-ebido ịchọpụta nchoputa na njiri mara onye ọrịa ahụ. A na-ewere ọgwụ ahụ ọnụ, n'agbanyeghị nri oriri, 0.01 g 1-2 ugboro n'ụbọchị. Na enweghị ụgwụ ọgwụgwọ dị mkpa, enwere ike ịbawanye otu nari ugboro abụọ, mana ọ gafere ogo ọgwụ 0.08 g kwa ụbọchị. O kwere omume ị aụ ọgwụ kwa ụbọchị otu ugboro, na-enweghị kewaa ọtụtụ usoro. Enwere ike ịbawanye dose ahụ naanị na nkwenye nke dibịa bekee ma ọ bụghị tupu izu anọ site na mmalite ọgwụgwọ.
Na-arịa ọrịa shuga
A na-eji ọgwụ ahụ eme ihe dị ka akụkụ nke usoro ọgwụgwọ zuru oke, na-elele nchịkwa glycemic nke ọma na usoro usoro ị doụ aro a tụrụ aro ya.
Nsonaazụ
Ọgwụ ọgwụ ahụ anaghị akpata mmeghachi omume achọghị. Ọtụtụ mgbe, a na-ahụ ya megide nzụlite nke hypersensitivity nke ndị mejupụtara ya ma ọ bụ ma ọ bụrụ na-anaghị ahụ usoro ọgwụ a tụrụ aro. Okwesiri ka onye okacha mara ka o nyechaa ogwu ahu ka o gha enye ya.
Ọkpụkpụ afọ
Akara nke akpụkpọ mucous nke ọnụ ma ọ bụ akpịrị, ọnyụnyụ dyspeptik, ọgbụgbọ, ihe mgbu nke afọ, ibelata agụụ, na imebi echiche ụtọ.
Sistemụ akwara Central
Na-agbadata nzụlite ọgwụ ahụ, mgbanwe mgbanwe ọnọdụ, vertigo, nsogbu asthenic, ike ọgwụgwụ ma ọ bụ mgbakasị ahụ, enwere ike ịmịcha anụ ahụ nke ọnya na-egbu egbu ma ọ bụ nwee mmerụ ahụ.
Site na usoro urinary
N'ọnọdụ ndị dịpụrụ adịpụ, a na-ahụta ọrịa ọnya.
Site na sistem iku ume
Ọtụtụ mgbe enwere ụkwara na-ekweghị akwụsị akwụsị, nke na-adịghị amị mkpụrụ nke na-agafe mgbe ọgwụgwọ ahụ gasịrị, mmetụta nke enweghị ikuku, nnukwu ọnya ọgbụgba nke mucosa pharyngeal, mgbu obi.
Na anụahụ
Nmeghachi omume nke anụ ahụ na anụ ahụ dị n'okpuru ala, dịka ịba ụba nke mmiri, nzethema na desquamation, ihe ọkụ ọkụ, itching, ntutu isi na-egbu egbu, isi mmiri, mmeghachi omume mpaghara ma ọ bụ sistemụ.
Site na usoro mkpụrụ ndụ ihe nketa
N'ọnọdụ ndị a na-adịghị ahụkebe, mbelata ikike, urination na-egbu oge ga-ekwe omume.
Site na usoro akwara obi
Enwere ike imeghachi omume nke akụkụ ahụ hematopoietic, dị ka mbelata nke ọnụ ọgụgụ ọbara ọbara ọbara n'ime ọbara, mbelata hemoglobin, agranulocytosis, mbelata nke ọtụtụ platelet, na ụkọ nke ụdị sel sel niile.
N’akụkụ nke usoro akwara obi, mmeghachi omume ndị a na-achọghị dịka enwere ike dị ka mbelata ọbara mgbali, ahụ erughị ala n’akụkụ obi, palpitations obi, ujo ụjọ, tachycardia, mmụba na lumen nke arịa ọbara.
Site na anụ ahụ na akwara
Ọtụtụ mgbe enwere mgbu azụ. N'ọnọdụ ndị na-adịghị ahụkebe, megide ndabere nke iji ọgwụ ahụ, ọrịa nkwonkwo na-emebi emebi.
Site na usoro ahụ ji alụso ọrịa ọgụ
Mmeghachi anaphylactoid, angioedema enwere ike.
Ahụhụ
Ọ bụrụ na ọgbụgba ọgbụgba na - emegharị ma ọ bụ ọzịza nke mkpụrụedemede ala nke ihu, ire ma ọ bụ olu ga - akwụsị ọgwụgwọ ya na ọgwụ ahụ ozugbo. Ọ bụrụ na ire ma ọ bụ akpịrị na-achọ ịkpaghasị ịgbanye ume na ngụgụ, ọgwụgwọ mberede na nlebara anya zuru oke tupu ịmalite ịme ihe mgbaàmà nke nfụkasị.
Mmetụta ikike ịchịkwa usoro
Mgbe ị na-a theụ ọgwụ, e kwesịrị ịkpachara anya mgbe ị na-achịkwa usoro na ịrụ ọrụ chọrọ nlebara anya, karịchaa na mmalite ọgwụgwọ, n'ihi nnukwu ọnya ọgbụgba na hypotension.
Ntụziaka pụrụ iche
N’otu oge, ị notụ nri anaghị emetụta ogo a absorụ ọgwụ, kama ọ na-abawanye oge iji ruo n’uche kachasị nke ihe arụ ọrụ.
Mgbe ị na-a medicationụ ọgwụ, a na-atụ aro ịhapụ nri ndị mara abụba na nri.
N'ọnọdụ ụfọdụ, ọgwụgwọ nke ndị na-egbochi enzyme enzyme enzyme na-esonyere mmepe nke hypoglycemia na ndị ọrịa nwere ọrịa mellitus, na-a oụ ọgwụ hypoglycemic nke ọnụ ma ọ bụ na-enweta insulin. Ihe na-arụ ọrụ nke ọgwụ ahụ na-eme ka ihe insulin na ndị ọrụ antidiabetic nwee ọrụ.
Jiri n'oge ime na lactation
Contraindicated na ime na lactation.
Oge ọkwa Akkupro nye ụmụaka
Ejighị ọgwụ ahụ na omume ụmụaka n'ihi enweghị data na nchekwa ya na arụmọrụ ya.
Jiri na agadi
Anabatara ya maka ojiji na-enweghị contraindications. Usoro akwadoro ọgwụ mbụ bụ 10 mg otu ugboro n'ụbọchị. N'okpuru nlekọta nke dibia bekee, enwere ike ịbawanye elu iji nweta mmetụta ọgwụgwọ chọrọ.
Ngwa maka ọrụ ezughi oke ọrụ
N'ime ndị ọrịa nwere akwara ịwa ahụ, a na-achọpụta mmụba na ọkara ndụ nke ihe na-arụ ọrụ, ya mere, ọ dị mkpa iji dozie dose ahụ, na-eburu n'uche njirimara nwepu ihe ngosipụta. Oke onunu ogwu kachasị site na 2.5 ruo 10 mg kwa ụbọchị. Thebawanye oke nke ọgwụ ahụ ga - ekwe omume naanị n'okpuru nchịkwa nke ọrụ anụ ahụ. Ọ bụrụ na emeghị ihe kwekọrịtara na ndụmọdụ ahụike nwere ike iduga nsị anụ ahụ, gụnyere ihe ọghọm nke ịmalite nnukwu akwara oke.
Dodoụbiga ya ókè
Mgbaàmà nke ịdoụbiga mmanya ókè bụ mmebi nke nguzo mmiri-electrolyte, arrhythmia siri ike, mbelata ugboro ugboro nke mkpịsị obi, na nkwarụ anya. A na-eme ọgwụgwọ site na nchịkwa ọgbụgba nke agbanwe agbanwe plasma iji bulie olu nke mgbasa na-ekesa. Ojiji nke usoro ọgwụgwọ dialysis nwere mmetụta a na-eleghara anya na mpụta nke ihe na-arụ ọrụ. N'ọnọdụ nke mbelata ọbara mgbali elu, ọ dị mkpa ịgwọ ọrịa Symptomatic na nkwado.
Mmekọrịta na ọgwụ ndị ọzọ
Ojiji nke ọgwụ mgbochi tetracycline na ọgwụ mgbochi ihe na -echeta nnabata nke tetracyclines. Usoro ọgwụgwọ na nkwadebe lithium na ndị na-egbochi ACE na-eme ka ọdịnaya lithium dịkwuo elu, na-abawanye ohere nke ịxụbiga mmanya ókè. Nkwadebe nke potassium na - eme ka ihe ndị na - eme ihe na - eme ihe na - eme ihe ike na - eme ka ọgwụ na - eme ihe ike. Ejikọtara ọgwụgwọ na ọgwụ ndị na-egbochi ọrụ ụmị ọkpụkpụ na-eme ka ohere nke ọrịa ọbara dịkwuo ala, gụnyere mbelata mkpokoro nke granulocytes na neutrophils.
Oge nchịkwa nke ọgwụ nwere hinapril na Allopurinol, Novocainamide, ndị na-ahụ maka cytostatic ma ọ bụ immunosuppressants na-abawanye ohere nke ịmalite leukopenia. Ọgwụ antihypertensive, ọgwụ anesthetics, na opioid analgesics na-eme ka mmetụta nke quinapril pụta, ebe ọgwụ mgbochi na-abụghị steroidal na-eme ka ike gwụ ya n'ihi njigide mmiri dị n'ahụ.
Mmanya ndakọrịta
Ethanol kwalite mmetụta antihypertensive nke ọgwụ.
Analogs
Ọgwụ nwere ọtụtụ analogues nke nọ n'otu otu ọgwụ. Themfọdụ n’ime ha bụ:
- Hinapril-C3;
- Prestarium
- Quinafar.
Ngwaọrụ ọgwụ siri ike nwere ike ịdị iche, yabụ, ekwesịrị ka ekwenye dọkịta ahụ.
Usoro ezumike Acupro sitere na ụlọ ahịa ọgwụ
Purchasezụta ọgwụ na-egbochi ihe mgbochi, ịkwesịrị ịhọrọ dọkịta.
Enwere m ike ịzụta na ndenye ọgwụ
Relelị site na ndenye ọgwụ.
Ọnụahịa Acupro
Ọnụ ego otu ọgwụ bụ 535-640 rubles.
Ọnọdụ nchekwa maka ọgwụ
Chekwaa na n ụlọ okpomọkụ a na-achịkwa (ọ dịghị elu karịa + 20 Celsius C). Zere ìhè anyanwụ. Belata ohere ụmụaka nwere ị .ụ ọgwụ.
Bọchị mmebi
Ọnwa iri atọ na isii gachaa ọgwụ ọ nabatabeghị.
Akkupro emeputa
Pfizer Nlụpụta Deutschland (Germany).
Nyocha maka Akkupro
Tupu ị theụ ọgwụ antihypertensive, a na-atụ aro ka ị gụọ nyocha nke ndị ọkachamara ọgwụ na ndị ọrịa.
Chekwaa na n ụlọ okpomọkụ a na-achịkwa (ọ dịghị elu karịa + 20 Celsius C). Zere ìhè anyanwụ.
Ndi dibia
Alevtina Ivanova (dibia akwara), 39 afọ, Ivanovo
Ọgwụ dị irè emebere iji belata ọbara mgbali elu ma melite ọrụ obi. Ogologo oge na-enyere aka ime ka mgbidi nke usoro akwara gbasie ike, melite ike ha. A na-enye ọgwụ ahụ dịka ọgwụ si dị, yabụ, ọkachamara kwesịrị ịkọwa ọgwụgwọ ziri ezi iji wezuga ọgwụ mgbochi ọ bụla ma belata ihe ize ndụ nke ịmalite mmeghachi omume achọghị.
Ndị ọrịa na-a theụ ọgwụ ahụ
Alina dị afọ 43, Krasnoyarsk
O were ya ọtụtụ ọnwa. Irè ọgwụ ahụ dị elu, nrụgide ahụ na-alaghachi na nkịtị mgbe awa 1-2 gachara. Agbanyeghị, a manyere ya ịhapụ usọbọ a n'ihi mmetụta ọjọọ ọ na-akpata - ọgụ nke ụkwara.
Anna, gbara afọ 28, Perm
Mama m ogologo oge gbalịrị ịnagide ọbara mgbali elu na aka ya, mana ịdị irè nke usoro ndị mmadụ adịteghị aka. Aghaghị m ịhụ dọkịta. Edere Mama a ọgwụ maka na ha chọpụtara nkụda obi. Mgbe ọgwụgwọ ya gasịrị, ndị na-egosi nrụgide laghachiri na nkịtị, ihe ịrịba ama nke ọbara mgbali elu na-apụ n'anya. Enweghị mmetụta dị njọ ọ bụla, ọ dịghị mkpa ka ịgbanwee ndị analogues ndị ọzọ dị oke ọnụ ma nwee mmeghachi mmetụta dị ole na ole.