Etu esi eji Metformin Canon?

Metformin Canon bụ ọgwụ hypoglycemic nke sịntetik sitere na ìgwè biguanide. A na-eji ya agwọ ọrịa shuga na oke ibu nke metabolism metabolism na-akpata.

International Nonproprietary Aha

Metformin.

Aha n'asụsụ Latin bụ Metformin.

A na-eji Metformin Canon mee ihe maka ịgwọ ọrịa shuga na oke ibu nke metabolism metabolism na-akpata.

ATX

A10BA02.

Ha weputara udi ya na ihe mebere ya

Ọgwụ dị n'ụdị mbadamba ihe mkpuchi-fim. Enwere mbadamba nkume nwere 500 mg, 850 mg na 1000 mg nke metformin.

Mbadamba ọgwụ nwere ọgwụ nke 500 mg bụ okirikiri, na mbadamba nkume ndị nwere usoro nke 850 mg na 1000 mg (Metformin ogologo) dị mma.

Ọgwụ dị n'ụdị mbadamba ihe mkpuchi-fim.

Ngwakọta nke mbadamba:

1. Metformin hydrochloride.
2. Polyethylene glycol (macrogol).
3. Povidone.
4. Talc.
5. Sodium stearyl fumarate.
6. Sodium carboxymethyl stachi.
7. Egwu pregelatinized.
8. Opadry II ọcha (onye na-ese ihe nkiri).
9. Titanium dioxide.
10. Polyvinyl mmanya.

Omume ọgwụ

Metformin na - egbochi gluconeogenesis, njikọ nke acids abụba n'efu, yana usoro nke Lipolysis (ndakpọ abụba) na oxidation abụba. N'otu oge ahụ, ị ​​ofụ glucose dị n'ahụ na-arụ ọrụ site na ịbawanye ụba nke sel na insulin.

Ọgwụ na-edozikwa ọdịnaya nke triglycerides na cholesterol n'ime ọbara. Enwere ntakịrị nwayọ n'ibu na ndị ọrịa buru ibu.

A na-atụ aro ọgwụ ahụ na ọnụnọ nke thrombosis, ebe ọ nwere mmetụta fibrinolytic. Metformin na - enyere aka wepu mkpụchi ọbara n'ime arịa ọbara.

A na-atụ aro ọgwụ ahụ na ọnụnọ nke thrombosis, ebe ọ nwere mmetụta fibrinolytic.

Mlọ ọgwụ

Mgbe a na -ewere ya ọnụ, ọgwụ ahụ na-eji nwayọ abanye na nri diges. Ntinye Metformin bụ 50%. Bioavailability anaghị agafe 60%. Nri ahụ ruru ihe kachasị na plasma n'ime awa 2-2.5.

Metformin na - ejikọ ya na albumin ọbara, mana ọ na - abanye ngwa ngwa ndu. Ọ napụrụ ya site n'ahụ ahụ akụrụ na-agbanweghi agbanwe. Oge oge ezumike bụ elekere 8-12.

Gịnị ka enyere ya?

Edere ọgwụ a maka ndị okenye na ụmụaka karịrị afọ 10 site na oke ibu na ụdị ọrịa shuga mellitus nke 2 (nke na-abụghị insulin). Enwere ike iji ọgwụ ahụ ma ụzọ abụọ yana nke abụọ (yana yana insulin).

Ihe ngosi ndi ozo maka ojiji bu:

1. Ọrịa ịba ọcha n'anya (dystrophy imeju). Ọrịa nke mkpụrụ ndụ hepatocytes (mkpụrụ ndụ akwara) na-agbanwe ka nke anụ ahụ.
2. Polycystic ovary. Ọrịa a na - ejikarị ọgwụ insulin eme ihe. E nwere oke mmepụta nke homonụ a na mmụba n'ọtụtụ shuga n'ime ọbara.
3. Hyperlipidemia. Ejiri oria lipids na lipoproteins n'ime ọbara wee mara ọrịa ahụ.

Ngosipụta maka ojiji bụ ịba ọcha n'anya.

Ihe ngbanwe

A na-egbochi ọgwụ a na mkpụrụokwu ndị a:

• anabataghị onye ọ bụla na metformin ma ọ bụ ndị zọpụtara ya;
• ọrịa shuga;
• ketosis na-arịa ọrịa shuga;
• ọrịa ọnya na-egbu egbu;
• arụ ọrụ ezumike;
• afọ ọsịsa ma ọ bụ ọgbụgbọ;
• ọrịa na-efe efe siri ike;
• hypoxia;
• ahụ ọkụ;
• sepsis
• nsogbu anaphylactic;
• infarction myocardial;
• akụkụ iku ume ma ọ bụ nkụchi obi;
• alisụrụma;
• lactic acidosis;
• ụkọ calorie;
• ụmụaka na-erubeghị afọ 10.

A machibidoro ọgwụ a iwu n'ihi ịnagide ọgwụ mmadụ na metformin ma ọ bụ ndị bu ya.

Ọgwụ na-contraindicated na sepsis.

A na-amịcha ọgwụ ahụ.

Ọrịa a na contraindicated na febrile ọnọdụ.

Jiri nlezianya

Mgbe ọ dị ihe karịrị afọ 60, enwere nnukwu ihe ize ndụ nke ịmalite ọrịa lactic acidosis. Ya mere, a na-enye ndị ọrịa ọrịa agadi ka ọ kpachara anya.

Etu esi ewere Metformin Canon?

O bu n'uche ogwu a ka eji eme ya.

Tupu nri ma ọ bụ mgbe e risịrị nri?

Iji belata mmetụta ọjọọ nke metformin na afọ, a na-atụ aro mbadamba nri na nri ma ọ bụ ozugbo.

Na-a drugụ ọgwụ maka ọrịa shuga

N'ikwekọ na ntuziaka ahụ, a na-enye ndị okenye nwere monotherapy ọgwụ 10001500 mg nke ọgwụ kwa ụbọchị. Ọ bụrụ na ọ dị mkpa, a na-eji nwayọ elu kwa ụbọchị ruo 2000 mg. Oke kachasị kwa ụbọchị bụ 3000 mg nke metformin. Enwere ike ekewa ubochi ubochi abuo na ato.

Mgbe ejikọtara ya na insulin, dose nke Metformin bụ 1000-1500 mg kwa ụbọchị. N'oge usoro ọgwụgwọ, enwere ike ịchọ mmegharị insulin.

Etu esi ewere ibu ibu?

Maka ọgwụgwọ nke oke ibu, ihe kpatara nke a bụ insulin na-eguzogide ọgwụ, a na-enye ọgwụ ahụ na usoro ọgwụgwọ nke 500 mg ozugbo. A na-abawanye ọgwụ ahụ na 2000 mg kwa ụbọchị, na-agbakwunye 500 mg kwa izu.

Metformin na-enyere aka belata ibu ma ejikọta ya na nri kwesịrị ekwesị.

Metformin na-enyere aka belata ibu ma ejikọta ya na nri kwesịrị ekwesị. Ma enweghi ike idobe ezigbo nri n'ihi ihe ize ndụ nke hypoglycemia.

Nsonaazụ nke Metformin Canon

Ka ị na-a drugụ ọgwụ a, enwere ike ịhụ mmetụta dị n'akụkụ akụkụ dị iche iche, mana n'ọtụtụ oge, eriri afọ na-arịa.

Ọkpụkpụ afọ

Site digestive usoro a hụrụ:

• ọgbụgbọ na ọgbụgbọ
• uto ọla n’onu;
• agụụ na-adịghị mma;
• anorexia;
• mgbu na afọ na eriri afọ;
• afọ ọsịsa
• ịmụba ikuku.

Site n'akụkụ nke metabolism

Mmetụta metabolism:

• lactic acidosis;
• Nri B12 (enweghi ike igwu vitamin).

Ọgwụ nwere ike ibelata agụụ.

Ọgwụ ahụ nwere ike ibute ọrịa anorexia.

Ọgwụ nwere ike bute ikuku gas.

Ọgwụ nwere ike iduga mmeghachi ahụ nfụkasị.

Na anụahụ

Ọcha ntutu, itching, na mmeghachi omume nfụkasị ndị ọzọ nke mpaghara enwere ike.

Usoro endocrine

A na-egosipụta nsonaazụ n'akụkụ oke ala glucose n'ọbara - hypoglycemia.

Ahụhụ

Site na ekweghị ibe nọrọ n'ọrụ ahụ, enwere:

• ihe odide
• akpụkpọ anụ
• urticaria;
• acha ọbara ọbara nke anụ ahụ.

Mmetụta ikike ịchịkwa usoro

Enweghị mmetụta na ịta. Agbanyeghị, n'ihi ihe egwu nke ibute hypoglycemia, ekwesịrị ịkpachara anya mgbe ị na-anya ụgbọala.

Ntụziaka pụrụ iche

Tupu arụ ọrụ na nyocha ya site na iji ọgwụ radiopaque, a na-akagbu ọgwụ. A na-ebupụ ọgwụ ọjọọ ụbọchị 2 tupu nyocha ahụ wee maliteghachi mgbe ụbọchị abụọ gachara.

Tupu ịwa ahụ, a na-akagbu ọgwụ.

Jiri n'oge ime na lactation

Ebe ọ bụ na ihe na-arụ ọrụ na-agabiga na Plasenta, a naghị atụ aro ka ụmụ nwanyị dị ime were ọgwụ a. Emebeghi ihe omimi nke oma banyere teratogenic utara nke metformin. Mgbe ụfọdụ ndị dọkịta na-enye ndị inyom dị ime ọgwụ ọgwụ a.

A na-atụ aro ị Breastụ ara n’oge a na-agwọ ya ka ọ kwụsị.

Ibute Metmụaka Metformin Canon

Ekwenyere ọgwụ a ka akpọgaara ụmụaka ụmụaka gbara afọ 10 n'okpuru nlekọta nke dọkịta.

Jiri na agadi

A naghị akwado ọgwụ ahụ maka ndị agadi (mgbe afọ 60) n'ihi nnukwu ihe ize ndụ nke lactic acidosis.

Ngwa maka ọrụ ezughi oke ọrụ

Contraindicated.

Ekwenyere ọgwụ a ka akpọgaara ụmụaka ụmụaka gbara afọ 10 n'okpuru nlekọta nke dọkịta.

Ihe ọgwụ a ga-eme ma ọ bụrụ na ọ nwere nsogbu ndị na-arụ ọrụ na ụlọ.

A naghị akwado ọgwụ ahụ maka ndị agadi (mgbe afọ 60) n'ihi nnukwu ihe ize ndụ nke lactic acidosis.

Jiri maka ọrụ imeju na-arụ ọrụ

Amachibidoro ịnabata ya.

Ngwakọta nke Metformin Canon

Mgbe ị na-a theụ ọgwụ ahụ na oke doses, mmepe nke:

• ọgbụgbọ na ọgbụgbọ
• afọ ọsịsa
• ahụ dị ala;
• mgbu afọ;
• Dizziness
• ịkụda mmụọ
• Coma

Mmekọrịta na ọgwụ ndị ọzọ

Ejiri nlezianya jiri ọgwụ a medicineụọ ọgwụ ahụ:

1. Danazole (onye na-elekọta hyperglycemic).
2. Chlorpromazine.
3. Ọgwụ.
4. Ngwunye nke sulfonylureas.
5. Ndị NSAID.
6. Oxytetracycline.
7. ACE na MAO na-egbochi.
8. Clofibrates.
9. Ọgwụ Hormonal (gụnyere ọgwụ mgbochi).
10. Diuretics (site na otu thiazide ma ọ bụ loop diuretics).
11. Nri nke nicotinic acid na phenothiazine.
12. Glucagon.
13. Cimetidine.

Mgbe ị na-a theụ ọgwụ ahụ na oke doses, ịda mba ga-ekwe omume.

A na-ewere ọgwụ ahụ na ịkpachara anya na ọgwụ Danazol.

Ọgwụ nwere mmachi na mmanya.

Ọ bụrụ na ngwakọta ndị dị otú ahụ dị mkpa, dọkịta ahụ na-akwadozi ị doseụ ọgwụ ahụ ma na-achịkwa ịba ụba nke shuga na lactic acid n'ime ọbara.

Mmanya ndakọrịta

Ngwaahịa a enweghị mmekorita na mmanya. Mmanya na-abawanye n'ihe ize ndụ nke hypoxia anụ ahụ, lactic acidosis na mmetụta ndị ọzọ.

Analogs

Analogues ama ama nke ngwaahịa a gụnyere Glucophage (Merck Sante, France), Formmetin (Pharmstandard, Russia), Siofor (Berlin-Chemie, France). Ọgwụ ndị a nwere otu ihe arụ ọrụ - metformin hydrochloride.

Ọgwụ dịka Metformin Teva na Metformin Richter bụ mkpụrụ ndụ ihe nketa. Ha na Metformin Canon bu otu na ihe eji eme ya, ma ndi ozo emeputara.

Ahịa ọgwụ na-ahapụ okwu

Enwere m ike ịzụta na ndenye ọgwụ?

Ọgwụ a dị na ndepụta B, ọ na-enyefe ọgwụ ọgwụ niile.

Ọnụ ego maka Metformin Canon

Ọnụ ego ọgwụ ọjọọ na Russia bụ 130-200 rubles. maka mbadamba 30.

Glucophage bụ otu n'ime ụdị analogues na-ewu ewu.

Ọnọdụ nchekwa maka ọgwụ

Chekwaa ọgwụ na okpomọkụ na-agaghị akarị 25 Celsius.

Bọchị mmebi

Ọgwụ dị mma maka afọ 3.

Emeputa

Onye mepụtara ngwa a bu CJSC Kanofarma Production, NPO FarmVilar (Russia).

Nyocha na Metformin Canon

Ndi dibia

Konstantin, afọ 42, St Petersburg

Anọwo m na-arụ ọrụ dị ka ọkà mmụta endocrinologist ruo ihe karịrị afọ 10. Edere ọgwụ a maka ndị ọrịa nwere ọrịa shuga na oke ibu. Ọ na - enyere aka ịhazi metabolism na ọkwa glucose ọbara. Adịghị m ahụkarị nsị na omume m.

Irina, 35 afọ, Krasnodar

Metformin bụ ezigbo ọgwụ hypoglycemic na ọgwụgwọ nke ụdị shuga 2. Ndị ọrịa m na-anabata ọgwụ ndị a nke ọma. Mgbe otu ọnwa na-a sugarụ ọbara shuga tụlee. Iji zere mgbu afọ, ana m akwado ịhapụ ị takeụ ọgwụ na afọ efu.

Ndị ọrịa

Valentin, 56 afọ, Belorechensk

Amụtara m banyere ọgwụ dịka Metformin, Siofor, Glucofage sitere na endocrinologist. Ọ gwara ha ka ha lụso ọrịa shuga ọgụ. Uru Metformin ma e jiri ya tụnyere ya bụ ọgwụ ọnụ ala. Ọgwụ nyeere aka ma ọ baghị akpata nsonaazụ.

Alexander, onye gbara afọ 43, Volgograd

A na m a drugụ ọgwụ a maka mgbochi ọrịa shuga. Ọbara ọbara malitere ịba, dọkịta ahụ kwukwara ka ọ bụrụ Metformin. Ahụghị m mmetụta ọ bụla na-adịghị mma n'oge ọgwụgwọ.

Ibelata ibu

Ekaterina, gbara afọ 27, Moscow

Mgbe m mụchara nwa, m bidoro gbakee ngwa ngwa. Enweghị m ike ịkwado nri siri ike ruo ogologo oge, yabụ m kpebiri ịnwale Metformin iji belata agụụ. Ọgwụ nyeere aka tufuo 5 n'arọ kwa ọnwa. Agụụ gụwara m, enweghị m ike iju ya.

Arina, 33 afọ, Irkutsk

Amalitere m ị theseụ ọgwụ ndị a na nkwado nke dọkịta. Ọgwụ na-ebelata agụụ na agụụ maka ụtọ. N'ime ọnwa nnabata, ịdị arọ m belatara 4 kilogram, nke a na m a gladụrị. Enweghị mmetụta ọ bụla.