A na-eji ọgwụ antihypertensive ọgwụ Losacor na-agwọ ọbara mgbali elu na iji gbochie nsogbu vaskụla na ndị ọrịa nọ n'ihe ize ndụ. Ọtụtụ nyocha dị mma banyere ọgwụ bụ n'ihi ọrụ ọgwụ dị elu yana ọnụ ala dị ọnụ.
International Nonproprietary Aha
Losartan (na Latin - Lozartanum).
Aha mba ụwa na-abụghị nke nwere ọgwụ Losacor bụ Losartan.
ATX
C09CA01.
Ha weputara udi ya na ihe mebere ya
N'ịre ahịa, ọgwụ ahụ dị n'ụdị mbadamba. Mbadamba ụrọ ọ bụla nwere 12.5 mg nke losartan potassium, nke a na-arụ dịka ntọala (ihe na-arụ ọrụ) nke ọgwụ. Ihe nke abuo:
- ọka ọka;
- pregelatinized stachi;
- microcrystalline cellulose;
- steeti magnesium;
- aerosil aerosil (silloon silicon dioxide);
- cellulose (ngwakọta nke cellulose na lactose monohydrate).
Akara mkpuchi nke mbadamba gụnyere quinolone dye edo edo, titanium dioxide, propylene glycol, talc na hypromellose.
Na mbadamba tebụl nke 7, 10 ma ọ bụ 14 mbadamba. Na ngwungwu nke mbadamba nke 1, 2, 3, 6 ma ọ bụ 9.
Akara mkpuchi nke mbadamba gụnyere quinolone dye edo edo, titanium dioxide, propylene glycol, talc na hypromellose.
Omume ọgwụ
Ọgwụ ahụ nwere mmetụta hypotensive ma bụrụkwa ihe mgbochi nke angiotensin 2, nke na-ejikọ ọtụtụ ndị na-anabata anụ ahụ ma nwee ọtụtụ ọrụ site na echiche nke microbiology, gụnyere ntọhapụ na vasoconstriction nke aldosterone na mkpali nke uto mkpụrụ ndụ dị mma.
Na mgbakwunye, ọgwụ na-ebelata ọbara mgbali, na-egbochi mmiri na njigide sodium n'ime ahụ, na-emekwa ka iguzogide mmega ahụ na ndị ọrịa nwere nkụda obi (adịghị ala ala obi).
Mlọ ọgwụ
Losartan na-etinye obi gị dum na nchịkwa ọnụ. Nri ahụ nwere ike ibute "isi ụzọ" site na imeju.
N'ihi usoro a, etinyere metabolite nọ n'ọrụ (carboxylated) na ọtụtụ metabolites na-adịghị arụ ọrụ. Akụkụ ahụ nwere bioavailability nke 33%. Nleta plasma kachasị elu erutela elekere 1 mgbe abanyechara. Ihe oriri anaghị emetụta profaịlụ ọgwụ nke ọgwụ antihypertensive.
Losartan na-enwe njikọ dị ike na protein plasma (ihe ruru 99%). Ihe dị ka 14% nke ọgwụ a na-atụgharị gbanwere ka ọ bụrụ ụdị metabolite nọ n'ọrụ.
Ihe ahụ na-ewepụta akụrụ ya na eriri afọ ya.
Ihe ngosi maka ojiji
Mbadamba nwere ike inye ndị ọrịa ụdị ikpe a:
- na ọnụnọ nke ọbara mgbali elu;
- iji belata ihe ize ndụ nke ịnwụ na ọrịa na ndị ọrịa nwere ihe ndị dị ize ndụ (mgbali ekpe ventricular, ọbara mgbali elu).
- ọgwụgwọ proteinuria na hypercreatinemia (ya na nke creatinine na albumin nke mmamịrị karịa 300 mg / g) na ndị ọrịa nwere ụdị shuga 2 nke ọrịa mellitus na ọbara mgbali elu;
- CHF na enweghị mmetụta nke ọgwụgwọ ya na ndị na - egbochi ACE;
- mgbochi ọrịa vaskụla na ịwa ahụ.
Ihe ngbanwe
Ejighị ngwaọrụ ahụ maka ọrịa imeju siri ike (karịa ihe 9 na Child-Pugh), ntachi obi lactose, lactation, ịtụrụ ime, ime ụmụaka, yana hypersensitivity na losartan na ọgwụ ndị ọzọ site na ọgwụ.
Jiri nlezianya
A na-eji nlezianya edepụta onye na-ahụ maka ọgwụ mgbochi ahụ na BCC belata, artpot hypotension, mmiri mmiri elektrolyte na mmiri, yana digoxin, diuretics, warfarin, carbon lithium, fluconazole, erythromycin na ọtụtụ ọgwụ ndị ọzọ.
Uzo esi ewere Losacor
Mbadamba ụrọ nwere ike iwere ya n'agbanyeghị nri, loda ya ma withụọ ya nke ọma. Ugboro iji - oge 1 kwa ụbọchị.
A na-agwọta ọbara mgbali elu na usoro nke 50 mg / ụbọchị.
Mgbe ụfọdụ, enwere ike ịbawanye ọgwụ ahụ ruo 100 mg ugboro abụọ n'ụbọchị. Oke kachasị bụ 150 mg / ụbọchị.
Iji gbochie ọrịa nke usoro obi.
Na-arịa ọrịa shuga
Iji kpuchido akụrụ na ndị ọrịa nwere ụdị ọrịa shuga 2 nke nwere proteinuria na-agbanwe agbanwe, a na-enye usoro onunu ogwu nke 50 mg / ụbọchị.
Usoro ị Theụ ọgwụ maka ọrịa shuga nwere ike ịbawanye ruo 100 mg kwa ụbọchị, na-eburu n'uche nsogbu nke nsogbu ọbara mgbali.
Enwere ike ịbawanye usoro ịba ụba ya ruo 100 mg kwa ụbọchị, na-eburu n'uche nrụgide nke ọbara mgbali elu.
Mmetụta ọghọm nke Losacor
N'ọnọdụ ka ukwuu, a na-eji ọgwụ ahụ nwayọ nwayọ. Ọnọdụ ndị dị na nsonaazụ ndị a yiri nke a mgbe ị na-eji paịọkụ.
Ọkpụkpụ afọ
Ogbugbu enwere ike, ihe mgbu nke epigastric, na - agba ume ka ị na-agbọ. N’ọnọdụ ndị a na-adịghị ahụkebe, ịba ọcha n'anya na-amalite.
Sistemụ akwara Central
Isi ọwụwa, ọgba aghara ụra, na obere nkụ nwere ike ime.
Na anụahụ
Akara uhie nwere ike ịpụta n’elu anụ ahụ.
Site na usoro akwara obi
Ọkpụkpụ obi ga-ekwe omume.
The Tụ ọgwụ ahụ nwere ike ibute ọrịa obi.
Site n'akụkụ nke metabolism
N'ọnọdụ ndị a na-adịghị ahụkebe, akpịrị ịkpọ nkụ na mmụba nke mkpokọta nke creatinine ma ọ bụ urea na plasma ọbara.
Ahụhụ
Ugbo, ncha, na itching ga-ekwe omume. N'ọnọdụ ndị na-adịghị ahụkebe, etinyere Quincke na-etolite etuto nke imi, ọnụ na akụkụ ahụ ndị ọzọ.
Mmetụta ikike ịchịkwa usoro
Enwebeghị nnyocha pụrụ iche gbasara nyocha nke mmetụta ọgwụ a nwere na nzaghachi psychomotor yana ikike iji ụgbọ ala.
Ntụziaka pụrụ iche
N'ime ndị ọrịa nwere BCC belatara, hypotension Symptomatic nwere ike ịmalite. Ọnọdụ ndị dị otú a chọrọ iji obere dos.
Na-emegide usoro ọgwụgwọ ọgwụ, ịkwesịrị iji nlezianya nyochaa ọkwa nke potassium n'ọbara ọbara, ọkachasị ndị agadi ọrịa yana arụ ọrụ akụrụ.
Ndị mmadụ n’oge agadi anaghị achọ nrụzigharị nke ọgwụ ole otu a na-atụle.
Jiri na agadi
Otu a nke ndi dibia achoghi imeghari udiri onye.
Inye umuaka
Maka ụmụaka na-erubeghị afọ 18, ọgwụ anaghị enye ya ọgwụ.
Jiri n'oge ime na lactation
A na - egbochi ọgwụ ọgwụ antihypertensive maka otu a ndị ọrịa.
Ngwa maka ọrụ ezughi oke ọrụ
N’ime oke akụrụ, emeghị ọgwụ mgbochi.
Jiri maka ọrụ imeju na-arụ ọrụ
N'ọnọdụ ezughi oke na ọrụ imeju ndị ọzọ na - arụ ọrụ (gụnyere ọrịa cirrhosis), usoro ọgwụ dị ntakịrị ka a na-edenye.
Do Overụbiga mmanya ókè nke Losacor
Ozi gbasara ịdoụ ọgwụ ọgwụ mgbochi oke amachaghị.
An anụbiga ihe ókè nke Losacor, ọbara mgbali nwere ike ibelata.
Ihe ịrịba ama: mbelata ọbara mgbali, tachycardia. Ọkpụkpụ anụ ahụ adịghị arụ ọrụ.
Mmekọrịta na ọgwụ ndị ọzọ
Ọgwụ ahụ na-abawanye nsonaazụ nke ndị nwere ọmịiko na ndị na-egbochi beta.
Nchikota nke ogwu ahu na ihe ndi aru nwere ike ime ka ha tinye ihe ndi ozo.
Fluconazole na rifampin na-ebelata ọkwa Plasma nke metabolites na-arụ ọrụ nke ihe na-arụ ọrụ.
NSAID nwere ike ibelata mmetụta nke ọgwụ mgbochi oke. Iji otu oge nke ọgwụ ndị a, na-achọ ndozi usoro onunu ogwu.
Losacor na-abawanye nsonaazụ nke ndị nwere ọmịiko na ndị na-egbochi beta.
Mmanya ndakọrịta
Ndị ọkachamara anaghị atụ aro ị alcoholụ mmanya mgbe ị na-ahyụ ọgwụ ọgwụ mgbochi.
Analogs
Mpempe ọgwụ dị ọnụ ala ma dị irè:
- Vasotens;
- Vasotens N;
- Losartan;
- Lozap;
- Xarten;
- Cantab;
- Edarby
- Angiakand;
- Hyposart;
- Sartavel.
Ahịa ọgwụ na-ahapụ okwu
Enwere m ike ịzụta na ndenye ọgwụ
Ọ gaghị ekwe omume ịzụta ọgwụ na-enweghị ndenye ọgwụ.
Ọnụ ego maka Losacor
Site na 102 rub. maka mbadamba 10.
Ọnọdụ nchekwa maka ọgwụ
N'ebe echekwara iru mmiri di elu, na odi elu.
Bọchị mmebi
Afọ 3
Emeputa
Companylọ ọrụ Bulgarian "Adifarm EAT".
Needkwesiri ịchekwa ọgwụ ebe a na - echekwa ya iru mmiri dị elu, na oke okpomọkụ.
Nyocha banyere Losacore
Victoria Zherdelyaeva (akwara gbasara ọrịa obi), 42 afọ. Ufa
Ezigbo ọgwụgwọ. A na-ahụ mmetụta ya dị egwu n'oge ụbọchị mbụ. A na-enye ọgwụ ka a na-ejikarị mgbali elu. Ọnụ ọnụ ọnụ Tupu iji ọgwụ ahụ, jide n'aka na ị gakwuru onye ọkachamara n'ịgwọ ọrịa.
Valentina Struchkova, 23 afọ, Moscow
Onye dibia bekee nyere ndi ogwu ogwu ogwu nyem nsogbu banyere obi oria. N'ikpe ikpe site na nsonaazụ ule ndị o mere n'oge na-adịbeghị anya na ụlọ ọgwụ mpaghara, ọgwụ ahụ "na-arụ ọrụ."
