Tricor 145 bu ihe nlebara anya nke anakpo onyunyo nke eji eme ya n’ulo ogwu gha belata cholesterol di elu. Mkpochapụ hypercholesterolemia dị mkpa iji belata ihe ize ndụ nke ịmalite atherosclerosis na iji gbochie mbido nke atherosclerotic na mgbidi nke arịa ahụ. Ọgwụ na-ebelata ihe ize ndụ nke ọbara egbochi n'ihi mwepu nke nchịkọta nke platelet ọbara.
International Nonproprietary Aha
Fenofibrate.
A na-eji tricor 145 mee ka cholesterol dị elu na triglycerides dị ala.
ATX
C10AB05.
Ha weputara udi ya na ihe mebere ya
Ọgwụ a dị na mbadamba ọcha maka nchịkwa ọnụ. Ngalaba ọgwụ ọ bụla nwere otu mgmịn 145 nke ihe na - arụ ọrụ - fenofibrate nanoparticles. A na-eji ihe ndị a na -eme ka iwelie ọsọ na izuzu nke mkpokọta yana ihe dị n'ọrụ:
- crospovidone;
- hypromellose;
- microcrystalline cellulose;
- sodium lauryl sulfate na docusate;
- mmiri ara ehi shuga, sucrose;
- silikion dioxide nke akpukpo ahihia akpukpo aru;
- stereta magnesium.
Tricor 145 dị na mbadamba ọcha maka nchịkwa ọnụ ma nwee 145 mg nke ogige na - arụ ọrụ - fenofibrate nanoparticles.
E kpuchie mbadamba nkume ndị ahụ na elu ihe nkiri dị na ya, nke na-agbaze n'okpuru ọrụ nke eriri afọ esterases. Ihe nkiri a gụnyere mmanya polyvinyl, titanium dioxide, talc, soya lecithin, xanthan gum.
-Dị ndị na-adịghị:
- gel;
- inje na ampoules.
Omume ọgwụ
Ọgwụ hypoglycemic bụụrụ otu nke fibrates. Usoro nke ihe na - arụ ọrụ sitere na ntinye aka nke ndị na - anabata ndị Alfa. N'ihi ịba ụba ọrụ ha, a na-eme ka lipolysis na mwepu nke lipoproteins nwere nnukwu triglycerides.
Fenofibrate bụ site na fibric acid, nke nwere ike imetụta ọkwa nke lipids n'ime ahụ mmadụ n'ihi mmegharị nke ndị na-anabata alfa. N'ihi mmezu nke mmetụta ọgwụgwọ ahụ, a na-ebelata mkpụkọ lipoproteins dị ala (LDL) ma belata ogo dị ukwuu (HDL). Ọnwụnwa preclinical kpughere mbelata cholesterol na 25%, triglycerides site na 45-55% yana mmụba nke itinye uche na HDL site na 10-30%.
N'ime oge ọgwụgwọ na-achọghị mgbanwe, a na-ebelata ihe ize ndụ nke ịmalite mgbanwe atherosclerotic na vaskụla endothelium na ohere nke guzobe plasta cholesterol na mgbidi nke n'ọbara ọbara. Site n'iji ọgwụ ahụ ogologo oge, ọnụ ọgụgụ ndị na-egosi mmerụ ahụ na-ebelata. Na ọnụnọ nke hyperuricemia, ndị ọrịa na-enweta uru ọzọ n'ụdị nbelata 25% na ọkwa uric acid.
Tricor 145 - ọgwụ hypoglycemic bụụrụ otu nke fibrates.
Mlọ ọgwụ
Mgbe ha abanye na eriri afọ, ọgwụ ndị a na - enweta esterases site na esterases iji mepụta fenofibroic acid. Ọgwụ ahụ na-agbasasị n'ọbara ọbara, ebe ọ na-eru ogo kachasị elu n'ime awa 2-4. Ngwaọrụ metabolic na-arụ ọrụ na-abanye n'ime mgbidi eriri afọ n'ụdị nanoparticles, yabụ ojiji nri nri anaghị emetụta ọnụego nnabata na izu oke nke bioavailability. N'ime akwara ọbara, 99% fenofibroic acid dị n'ọrụ na-etolite plasma albumin.
Ọgwụ ọgwụ anaghị eme mgbanwe n’ime sel akwara. Ọkara ndụ nke metabolite nọ n'ọrụ bụ awa 20. Ọgwụ na-ahapụ ahụ mmadụ na mmamịrị n'ime otu izu.
Ihe ngosi maka ojiji
A na-eji ọgwụ ahụ eme ihe maka cholesterol dị elu na triglycerides ma ọ bụ dyslipidemia agwakọta na ịdị ala nke usoro ọgwụgwọ nri, mmụba anụ ahụ na ụzọ ndị ọzọ na-abụghị ọgwụ na-alụ ọgụ megide oke ibu. Karịsịa na ọnụnọ nke ọbara mgbali elu na àgwà ọjọọ.
N'ime usoro ọgwụgwọ, enwere ike iji ọgwụ wepụ ọgwụ metabolic na hyperlipoproteinemia nke abụọ naanị ma ọ bụrụ na ọkwa nke lipoproteins na-adịgide ma ọ bụrụ na ọgwụgwọ nke usoro isi mmalite adịghị arụ ọrụ.
A na-eji tricor 145 mee ihe cholesterol elu na triglycerides ma ọ bụ dyslipidemia agwakọtara na usoro nri nri na-adịghị mma.
Ihe ngbanwe
Ọgwụ na-ike contraindicated na ndị na-esonụ ikpe:
- na ụyọkọ galactosemia, ụkọ lactase na fructose, ọrịa galactose-glucose, sucrose-isomaltase malabsorption;
- ọnụnọ nke nghọta dị ukwuu na ọkụ, maka ihe owuwu Tricorra;
- imeju na akụrụ ime;
- phototoxicity n'oge ọgwụgwọ na Ketoprofen, fibrates;
- usoro ọnya na ọnya ụgba;
- mmeghachi omume anaphylactic na ahụekere, soy na butter.
Jiri nlezianya
Ọ dị mkpa inyocha ọnọdụ onye ọrịa ahụ mgbe enyere ya iwu banyere usoro ọrịa ndị a:
- ịdị obere gbasara akụrụ na akwara ịba ọcha n'anya;
- mmanya na-egbu egbu;
- ịka nká;
- ụdị ọrịa akwara ọkpụkpụ;
- nje ọgwụgwọ na anticoagulants na-apụtaghị ìhè na ndị na-egbochi HMG-CoA.
Ọ dị mkpa inyocha ọnọdụ onye ọrịa mgbe a gwara ya ka ịmalite ị ofụbiga mmanya ókè.
Etu ị ga - ewere Tricor 145 mg
A ga-ewererịrị okwu ndị a n'ọnụ na-akọghị. Mbibi nke akpụkpọ ahụ ihe nkiri nwere ike ibute mbelata mgbanwe nke fenofibrate n'ime fenofibric acid dị n'ọrụ. Enwere ike ị medicineụ ọgwụ ahụ ụbọchị niile, n'agbanyeghị nri. Ndị ọrịa toro eto kwesịrị ị tabletụ mbadamba 1 nke 145 mg kwa ụbọchị otu ugboro.
Mmetụta egbugbere ọnụ na-adị irè mgbe a na-aga n'ihu na nri nri yana ọnọdụ nke mmega ahụ dị ụba. Ndị ọrịa a treatedụrụ ọgwụ ruru 160 mg nke ọgwụ a achọghị mbelata nke usoro iji ọgwụ were rue 145 mg.
Na-a drugụ ọgwụ maka ọrịa shuga
Ọgwụ a anaghị emetụta ọkwa nke glucose n'ọbara na ọrụ nke mkpụrụ ndụ beta nke pịkụl. Ya mere, ndị ọrịa na-arịa ọrịa shuga mellitus achọghị usoro nhazi nke insulin na ọgwụ hypoglycemic.
Nsonaazụ
Mmeghachi omume na-emetụta ahụ gị na-apụta n'ihi usoro ịhọrọ fenofibrate nke ọma.
Ọkpụkpụ afọ
A na-egosipụta nsogbu usoro nri dịka ihe mgbu na epigastrium, vomiting, gas gas na afọ ọsịsa. Ọria akwara puru ime.
Ndị ọrịa nwere ọrịa mellitus na-arịa ọrịa anaghị achọ nhazi nke insulin na ọgwụ hypoglycemic.
Ahụhụ Hematopoietic
N'ọnọdụ ndị a na-adịghị ahụkebe, yana igbochi sistem ma ọria ọbara, ụkọ leukocyte na ịba ụba haemoglobin.
Sistemụ akwara Central
A na-ahụta nsogbu ụjọ akwara na ogo nrụrụ, isi ọwụwa.
Site na usoro akwara na uru ahụ
N'ọnọdụ ndị na-adịghị ahụkebe na nke pụrụ iche, mmepe nke mgbasa myalgia, akwara mgbu na spasms, adịghị ike, myositis, nnukwu necrosis nke akwara anụ ahụ nke akwara nke ọkpụkpụ.
Site na sistem iku ume
E nwere ntakịrị ihe ize ndụ nke ịmalite ịmịnye mmadụ ọrịa ọgbụgba.
Na anụahụ na abụba subcutaneous
Ihe omume mmeghachi ahụ anụ ahụ na-adịghị mma, nke e ji ọdịdị ihe ọkụ, urticaria, ezigbo itching. N'ọnọdụ ụfọdụ, ịdị ọcha na-abawanye na akpụkpọ ahụ, mmadụ na-amalite ida ntutu. Ọrịa nwere ike ibute ọnya, ya na blisters.
Site na usoro mkpụrụ ndụ ihe nketa
Enwere ike ịbawanye ụba na serum creatinine na ọkwa uric acid megide ndabere nke njigide urinary.
Site na usoro akwara obi
Ihe na-egosi ọghọm nke akwara ozi bụ thromboembolism venous, nke gụnyere akwara umeji na thrombosis venous na nsọtụ ala.
Usoro endocrine
Ikekwe ụba mmụba.
N'akuku nke imeju na akụkụ biliary
N'ọnọdụ ka ukwuu, ọrụ na-abawanye na ntinye uche nke hepatic aminotransferases n'ọbara ọbara na-abawanye. N'ọnọdụ ụfọdụ, cholelithiasis na-amalite, ikekwe ọrịa imeju na-egbu oge. Ọ bụrụ na ihe ịrịba ama nke ịba ọcha n'anya na-apụta n'ụdị jaundice na itching, a na-atụ aro ka ọ gaa nyocha ụlọ nyocha iji gosipụta nchoputa ahụ. Mgbe inwetara nsonaazụ dị mma, a na-akagbu iji fenofibrates.
Ntụziaka pụrụ iche
Tupu ịmalite usoro ọgwụgwọ ọgwụ, ọ dị mkpa iji kpochapụ etiological na-akpata hypercholesterolemia nke abụọ, nke nwere ike ime megide ndabere nke ụdị ọrịa shuga 2 nke mellitus, ahoụrụma. A na-atụ aro ịdị irè ọgwụgwọ iji gosipụta nyocha nke ogo abụba ọbara. Ọ bụrụ na enweghị ọgbụgba belata ihe dị n’ime ọnwa atọ, ọ dị mkpa ka gị na dọkịta gị mata maka dochie ọgwụ ahụ.
N'ọnọdụ ụfọdụ, megide ndabere nke ọgwụgwọ ọgwụ, mmepe nke usoro mkpali na pancreas ga-ekwe omume.
N'ọnọdụ ụfọdụ, megide ndabere nke ọgwụgwọ ọgwụ, mmepe nke usoro mkpali na pancreas ga-ekwe omume. Ihe na-ebute oria a puru iche nwere ike ibu okwute na oria ojoo n’azu n’otutu ogwu a na-aghaghi idi nsogbu megidere onodu ahu ike.
Mmetụta ikike ịchịkwa usoro
Ọgwụ a adịghị doping ma ọ bụ psychotropic, adịghị emetụta ọrụ nke sistemụ akwara na akụkụ ụjọ. Ya mere, n'oge ọgwụgwọ Triicore, a na-ahapụ ya ka ọ chịkwaa usoro mgbagwoju anya na ụgbọ ala, nke chọrọ ịbawanye ụba na mmeghachi ngwa ngwa.
Jiri n'oge ime na lactation
Amachibidoro ị -ụ ọgwụ na-egbu egbu mgbe amụrụ ime. Mgbe ị na-edepụta ọgwụ n’oge a na-enye nwa ara, ọ dị mkpa ka ịnyefee nwata ahụ nri na ngwakọta ụmụ ọhụrụ wee kagbuo lactation.
Crib na-edegara ụmụaka TRICOR 145 mg
A machibidoro onye na-ahụ maka ọbara hypolipPs iji ruo afọ 18 n'ihi enweghị ihe ọmụma banyere mmetụta fenofibroic acid na mmepe nke ahụ mmadụ na ụlọ akwụkwọ ọta akara na oge uto.
Jiri na agadi
Ndị dị afọ 70 ga-akpachapụ anya nyochaa ọnọdụ ha n'oge ọgwụgwọ fenofibrate.
Ngwa maka ọrụ ezughi oke ọrụ
Ọgwụ a na contraindicated na nnukwu gbasara akụrụ odida.
Jiri maka ọrụ imeju na-arụ ọrụ
Amachibidoro ọgwụ a maka ndị nwere ọrịa imeju siri ike iji ya.
Dodoụbiga ya ókè
Egobeghi ihe doro anya na-egbochi ihe anya. Nke a bụ n'ihi enweghị nnọchi oke. Iji otu mbadamba ọgwụ dị elu, ọ ga-ekwe omume ịbawanye nsonaazụ yana ịbawanye ugboro ole ha na-eme. Ọ bụrụ n ’ị na-enyo n’ ihe ịrịba ama nke ịdoụbiga mmanya ókè, ị ga-achọ enyemaka ọgwụ. Ọgwụ ahụ adịghị agwọ ya.
Amachibidoro ị toụ mmanya n'oge Tricor na-agwọ ọrịa.
Mmekọrịta na ọgwụ ndị ọzọ
Fenofibrate na ngwaahịa metabolic ya anaghị egbochi cytochrome P450 isoforms.
Mmanya ndakọrịta
Amachibidoro ị toụ mmanya n'oge Tricor na-agwọ ọrịa. Mmanya ethyl nwere ike imebi mmetụta nke lipid, belata mgbochi nke usoro ịba ọcha n'anya na ụjọ.
Ngwakọta ndị amachibidoro
Fenofibroic acid na-akwalite mmetụta ọgwụgwọ nke anticoagulants maka iji ọnụ. N'ihi ngwakọta a, ọbara ọgbụgba nwere ike ịmalite. Mmetụta ahụ na-adịghị mma bụ n'ihi mwepụta nke anticoagulant site na saịtị na-ejikọ protein.
Na mbido ọgwụgwọ ọgwụ na fenofibrate, a na-atụ aro ka ị gaa hụ dọkịta banyere mkpa iji belata usoro ọgwụ kwa anticoagulants kwa ụbọchị site ⅓. A na-eme nhọrọ ọgwụ na-esote usoro kwekọrọ n'ụkpụrụ nke INR.
Site n'iji otu mbadamba ọgwụ dị elu, ọ ga-ekwe omume ịbawanye nsonaazụ yana ịbawanye ugboro ole ha na-eme.
Ngwakọta anaghị atụ aro
N'ihi nnukwu ihe egwu dị na nsí nsí na akwara, anaghị atụ aro iji fenofibrate na ihe mgbochi HMG-CoA reductase na ihe mmebi fibrate.
Mgwakọta chọrọ ịkpachara anya
A na-atụ aro ka ị na-elele ọrụ akụrụ mgbe niile na mgbe a na-ahọpụta Tricor na Cyclosporine ma ọ bụ ọgwụ nje. Mgbe ejikọtara, enwere ihe ọghọm nke ọdịda akụrụ. Site na mgbanwe siri ike na paradaịs, ịkwesịrị ịkwụsị ị Tụ Tricor.
Analogs
Enwere ike dochie ọgwụ ahụ na otu n'ime analogues ndị a:
- Lipantyl;
- Fonfibrate Canon;
- Gofibrat;
- Lofant.
Ọnọdụ ezumike nke Treicor 145 mg site na ọgwụ
Ere ọgwụ dị naanị na ndụmọdụ ahụike ọfụma.
Enwere m ike ịzụta na ndenye ọgwụ
A naghị ere ọgwụ ahụ na-enweghị ọgwụ dọkịta n'ihi oke ihe egwu nke mmetụta ndị ọzọ ma ọ bụrụ na ejiri ya n'ụzọ na-adịghị mma.
Ọnụahịa
Nkezi ọnụahịa nke mbadamba bụ 931 rubles.
Ọnọdụ nchekwa maka ọgwụ
Ọ dị mkpa ịnwe ọgwụ ahụ na okpomoku dị ala na-adịghị ala site na ụzarị ultraviolet n'oge okpomọkụ ruo + 25 Celsius.
Bọchị mmebi
Afọ 3
Onye nrụpụta Tricor 145 mg
Reciphon Fontaine, France.
Enwere ike dochie ọgwụ ahụ na Fenofibrat Canon analog.
Nyocha banyere Tricor 145 mg
Na ntanetị, ndị dọkịta na ndị ọrịa na-ahapụ ihe dị mma. Nyocha na-ezighi ezi na-ebilite n'ihi ọdịdị nke mmetụta ndị ọzọ.
Ndi dibia
Romanov Denis, endocrinologist, St. Petersburg
Nke a bụ ọgwụ na-agbatị egbugbere ọnụ, mana Tricor na -ebelata triglycerides ọbara n'ụzọ dị ukwuu. Ana m akwado iji ya maka dyslipidemia nke ụdị IIa, IIb, III na IV. Usoro ọgwụgwọ usoro onunu ogwu na oge ọria guzobere na usoro nke ndị ọrịa. Ana m adọ gị aka na ntị na omume, ọgwụ nwere obere ala belata cholesterol. Mbadamba ụrọ bụ contraindicated maka ndị nwere ọrụ imeju na-adịghị ahụkebe.
Ndị ọrịa
Gennady Likhachev, 38 afọ, Yekaterinburg
M na-ahapụ nyocha na-ezighi ezi banyere Tricor. Dọkịta ahụ nyere ọgwụ ahụ ka ọ bụrụ onye nnọchi Torvacard, n'ihi na enwere ọkwa HDL dị ala. Ka ọnwa 4-5 gachara mbanye, ahụrụ m ka ọghọm, ọgbụgbọ, na ọgbụgbọ oge. N'ime ọnwa 8-9 nke ọgwụgwọ na-egbochi nchekwa na ịmịnye ọbara na ọdịdị nke colic n'ime akpịrịkpa, enyere usoro ịme ihe. Nchoputa nke ihe otite ji ekpughe viscous bile na otutu okwute. Mgbe ọgụ ahụ mechara, ọgụ ahụ kwụsịrị.
Roman Sorokin, 53 afọ, Stavropol
Enwere m ọrịa mamịrị retinopathy, nke metụtara ọria laser na ịwa ahụ n'anya m karịa otu ugboro. Iji mee ngwangwa, ana m anabata Tricor, nke na-anagide ọrụ ya nke ọma. N'okwu a, ọgwụ ahụ na-eme ka oke cholesterol dị n'ọbara na ọkwa dị mma. M na-a theụ ọgwụ ahụ kwa oge kwa ọnwa 10, ndị na-esote ezumike ọnwa 2. Ahụghị m mmetụta ọ bụla na mmeghachi omume nfụkasị ahụ n'oge oke ahụ dum.
