Ntụziaka maka iji Glidiab MV

Usoro ọgwụgwọ maka ọrịa shuga abụghị naanị mgbanwe nri, kamakwa iji ọgwụ pụrụ iche.

Ọrịa ụdị nke abụọ, ndị mmadụ na-edekarị ọgwụ iji nweta ọkwa glycemia nkịtị. Otu ọgwụgwọ dị otú ahụ bụ Glidiab MV.

Ozi izugbe, ihe mejupụtara na ụdị ntọhapụ

Ọgwụ Glidiab MV bụ otu sitere na usoro sulfonylurea (ọgbọ abụọ), yabụ ebum n'uche ya iji kpalite sel beta dị na pancreas.

A na-emepụta ọgwụ ahụ na mpaghara Moscow site na ụlọ ọrụ ọgwụ Akrikhin ma a na-ahụta ka ọ bụ analog nke mbadamba ụrọ hypoglycemic Diabeton MV, nke arụpụtara na France. Lọ ọrụ ahụ nwere usoro onunu ogwu eji nweputara ndọtị eweghachite.

Ogwu a di n ’ud i mbad i nwere ihe oma. Ha yiri mpụta nke clinda ewepụghị. Ọgwụ ahụ dị na ngwugwu nke mbadamba 30 ma ọ bụ 60.

E jiri ya tụnyere Diabeton MV, nke nwere onodu ogwu nke 0.06 g, Glidiab MV nwere ọkara ihe eji arụ ọrụ (0.03 g).

Ngwakọta:

• Gliclazide bụ isi ihe;
• cellulose (microcrystalline);
• hydroxypropyl methylcellulose;
• steeti magnesium;
• Aerosil;

Edere ọtụtụ ndị ọrịa Glidiab 80, nke nwere ihe nọ n'ọrụ, ọ bụghị mgmịn 30, mana 80 mg na mbadamba ọ bụla.

Omume ọgwụ

Ngwa nke Glidiab MV na-emetụta ahụ dịka ndị a:

• meekwa ka mmiri ọgwụ insulin na-arụ ọrụ nke ọma.
• mụbaa anụ ahụ uche na homonụ mepụtara;
• belata oge dị n’ime oge a na-a foodụ nri ruo mwepụta insulin;
• n'okpuru mmetụta nke ọgwụ a, a na-eweghachi insulin insulin n'oge mmalite ma e jiri ya tụnyere ọgwụ ndị ọzọ na-eme ka mmiri na-enyocha;
• mee ka microcirculation dịkwuo n'ihi nsị mkpụrụ ndụ platelet, mweghachi nke nje ahụ na -akpata ihe na obere ihe ize ndụ nke microthrombosis;
• belata glycemia;
• nye aka na mkpochapu nke protenuria;
• belata mmepe nke retinopathy;
• na-enyere aka ịbelata oke, dị n'okpuru nri nri.

Mlọ ọgwụ

Usoro ịmịkọrọ, nkesa n'ime ahụ, metabolism na excretion nke mmiri mejupụtara dị ka ndị a:

1. Egwu. Ọgwụ fọrọ nke nta ka ọ banye n’ozi ahụ n’eriri afọ (eriri afọ). Ọbara ya na-abawanye na plasma nwayọ, wee rute nke kachasị site n'oge nchịkwa mgbe elekere isii ma ọ bụ awa iri na abụọ gachara. Nri anaghị emetụta ọnụego nnabata. Ọgwụ dị irè maka 24 awa.
2. Nkesa. Nkwado nkwukọrịta na protein ndị dị na plasma na ọgwụ ọgwụ dịka 95%.
3. Metabolism. Usoro a na-aputa n'ime imeju, akwara site na nguzobe nke metabolites na-adịghị arụ ọrụ.
4. Ojiji. Mgbapụta na-aputa site na akụrụ n'ụdị metabolites, naanị 1% nke ọgwụ na-apụta na mmamịrị. Kpochapu ọkara ndụ ọgwụ ahụ na-apụta na awa iri na isii.

Usoro ọgwụ ọgwụ nke ndị ọrịa nwere ndị agadi anaghị agbanwe agbanwe.

Ihe ngosi na contraindications

Mbadamba ọgwụ Glidiab MV bụ ọgwụ hypoglycemic, ya mere, a na-eji ya na ọgwụgwọ nke ọrịa shuga 2, mgbe ụzọ ndị ọzọ nke iwetulata glucose alaghachighị onye gosipụtara na nkịtị.

Ihe ndi choro igbochi ogwu a:

• ketoacidosis;
• arụ ọrụ akụrụ;
• Ọrịa shuga ;dị 1;
• coma (ọrịa mamịrị ma ọ bụ hyperosmolar);
• arụmọrụ;
• mmerụ ahụ
• mgbochi ụbụrụ;
• ime
• ọnọdụ na - akpata hypoglycemia (dịka ọmụmaatụ, ọrịa nke ọrịa na - efe efe);
• leukopenia;
• oke oku;
• hypersensitivity na bekee na mejupụtara ngwaahịa a;
• inye ara.

Ntuziaka maka iji ya na ndụmọdụ pụrụ iche

Usoro ị drugụ ọgwụ ahụ dabere na njirimara nke ọrịa shuga na ngosipụta ya, yabụ ndị dọkịta ahọpụtara ya n'otu n'otu maka onye ọrịa ọ bụla.

Na mbido ị theụ ọgwụ ahụ, a na-atụ aro ị aụ ọgwụ 30 mg ma ọ bụ mbadamba 1. Dabere n'ọnọdụ onye ọrịa n'oge ọgwụgwọ, enwere ike ịba ụba nke ihe na-arụ ọrụ kwa ụbọchị ruo 120 mg (oke kachasị).

A na-ewere mbadamba okwu ọnụ n'oge nri ụtụtụ (otu ugboro n'ụbọchị). Pairrụ ọrụ akụrụ dị nwayọ (na creatinine si na 15 ruo 80 ml / min) anaghị achọ idozi dose.

Na mbido ọgwụgwọ ọgwụ ma rue mgbe ahọrọ ọgwụ dị mkpa, ndị ọrịa na-enwekarị hypoglycemia ekwesịghị ịrụ ọrụ chọrọ nzaghachi ngwa ngwa ma ọ bụ nlebara anya dị ukwuu.

Womenmụ nwanyị enweghị ike iji ọgwụ eme ihe n’oge ọmụmụ nwa, yana inye nwa ara.

Oru oke imebi akụrụ ma ọ bụ imeju machibidoro iji ọgwụ eme ihe ọbụla.

Iwu Ngwa:

1. Ihe achọrọ iji nweta nsonaazụ nke ngwa ahụ bụ isochi usoro nri na mmega ahụ na-agafeghị oke. N'ime nri ụbọchị, carbohydrates kwesịrị ịnọ na obere ego.
2. Ọ dị oke mkpa na a na-enyocha glycemia tupu yana mgbe nri gasịrị, ka enwere ike idozi ọnụọgụ dabere na nsonaazụ nha.
3. Maka usoro ịwa ahụ ma ọ bụ oria na-arịa ọrịa diski, a ga-eji ọgwụ insulin dochie ọgwụ ahụ.
4. Iji zere ịda ọrịa hypoglycemia, yana mmeghachi omume disulfiram, ị drinkụ mmanya.
5. A machibidoro ya iwu iri nri, leghara nri ndị dị na nri n'oge mmalite nke agụụ.
6. Tupu ịrụ ọrụ arụ ọrụ siri ike, a ga-ebelata dose ahụ.

Ihe kachasị emetụta ọgwụ hypoglycemic bụ:

• ndị mmadụ n’oge agadi;
• ndị ọrịa na-enweghị ike iri ezigbo nri;
• ndị nwere ahụ adịghị ike;
• ndị ọrịa nwere ọrịa ọrịa ụbụrụ nke pituitary-adrenal insufficiency.

Mmetụta akụkụ na ị andụbiga mmanya ókè

Iwere mbadamba nkume nwere ike ibute mmeghachi omume ndị a na mmadụ:

• n'ihe metụtara usoro endocrine - hypoglycemia na njiri mara nke isi ọwụwa, ọsụsọ, adịghị ike, nkụda mmụọ, mgbakasị ahụ, ịma jijiji, enweghị mmụọ, ọhụhụ ụzọ na nhazi nke mmeghari;
• site na nri diges - dyspepsia, anorexia, ọgba aghara na imeju;
• leukopenia, thrombocytopenia, anaemia;
• Ngosiputa nfụkasị (itching, ihe ngbu, ma ọ bụ urticaria).

Site na ịdoụbiga ọgwụ ókè, hypoglycemia na-apụta. Iji wepu ihe mgbaàmà ya, o zuru ezu iri ọtụtụ carbohydrates, ma ọ bụrụhaala na onye ahụ maara ihe. N'ọnọdụ ebe onye ọrịa enweghị ike ị takeụ nri n'onwe ya, ekwesịrị inye ya ọgwụgwọ glucose ọbara (40%) yana ntụtụ glucagon. Mgbe ị laghachitere onye na-arịa ọrịa shuga, ị ga-achọ nri ọzọ iji zere ịda glucose ugboro ugboro.

Mmekọrịta na ọgwụ ndị ọzọ na analogues

Ojiji nke ọgwụ ndị ọzọ na njikọta na Glidiab MV nwere ike ịkwalite ma ọ bụ ibelata mmetụta hypoglycemic.

Ejikọtara ọgwụ na ọgwụ dịka:

• Ndị na - egbochi ACE;
• ndị na - egbochi antifungal (fluconazole);
• NSAIDs;
• ọgwụ mgbochi;
• Fibrates;
• ọgwụ mgbochi ụkwara nta;
• Salicylates;
• Pentoxifylline;
• Ethanol;
• ọgwụ nke na - egbochi tubular secretion.

A na-ebelata hypoglycemic mmetụta mgbe ejikọtara ya na ọgwụ ndị a:

• mgbochi;
• thiazide diuretics;
• Furosemide;
• homonụ iji nọgide na-arụ ọrụ thyroid;
• nkwadebe lithium;
• estrogens;
• ụzọ nke mgbochi afọ ime.

N'ime ọgwụ ndị nwere otu mmetụta dị ka mbadamba Glidiab MV, ihe ndị a ka edepụtara bụ:

• Meglimide;
• Ọlta
• Glibetic;
• Clay;
• Glimepiride;
• Eglim;
• Glairie
• Glibenclamide;
• Glurenorm.