Fructosamine maka ọrịa shuga

Thefọdụ n'ime protein anyị na ọbara anyị nọ na shuga dị n'ụdị glycated. Di elu larịị kwa ụbọchị glucose dị ukwuu, ka ukwuu pasent protein na-anabata ya. Iji chọpụta nkwụghachi ụgwọ nke ọrịa shuga, iji chọpụta ihe ize ndụ nke ọrịa a, ị nwere ike iji nyocha maka fructosamine.

N'agbanyeghi eziokwu na enweghi ike idebe ihe omumu a, o bu ihe omuma, karia mgbe ndi ozo ghoro usoro ohuru. Enwere ike iji ọkwa fructosamine gbakọọ nkezi shuga n'ime izu ole na ole gara aga wee buru amụma banyere oke nke gemoclobin glycated dị na ya. N'ụfọdụ, nyocha a bụ naanị ụzọ iji chọpụta shuga dị na mbụ a na-achọpụtaghị na shuga.

Fructosamine - gịnị ka ọ bụ?

Ogige ahụ nwere protein nke usoro dị mfe - albumin. N'ime ngụkọta nke protein, òkè ya bụ 52-68%. O nwere obere ụmụ irighiri ihe ma nwee ikike nke ọma. Site na nke a, ọ nwere ike ibugharị bilirubin, acids faty, ụfọdụ homonụ na ọgwụ site na arịa. Albumin nwere ike ịmeghachi glucose. Fructosamine bu ihe si na mmeghachi omume di otua. Ọkpụkpụ na-agba n’iru ọsọ ọsọ mgbe enwere ọtụtụ shuga n’ime ọbara ma bulie ọkwa ya elu ruo ogologo oge. N’ịmepụta fructosamine, a na-agakọ mmiri haemoglobin nke ọbara ọbara.

Njikọ nke albumin nwere glucose kwụ chịm. Mgbe ọkwa shuga alọghachirila na nkịtị, fructosamine anaghị agbaji, kama ọ ka na-adị ọbara. Protein na-etisasị naanị mgbe izu 2-3 gachara, oge niile enwere ihe akaebe banyere ima elu shuga n'ime ọbara. Mkpụrụ ndụ ọbara ọbara na-ebi ogologo oge, ruo ọnwa anọ, yabụ, oke nke haemoglobin glycated na-enye gị ohere inyocha ogo ọgwụgwọ maka ogologo oge karịa ọkwa nke fructosamine.

Ọrịa shuga na oke nrụgide ga-abụ ihe mgbe ochie

• Normalization shuga -95%
• Mwepu nke akwara mbufụt - 70%
• Mwepu nke obi ike -90%
• Bibie ọbara mgbali elu - 92%
• Mmụba na ume n'ụbọchị, na-eme ka ụra na-ehi ụra n'abalị -97%

Ebu ụzọ kọwapụta nyocha ahụ na 1982. E mechara chọpụta na enwere ike ịchọpụta ọrịa shuga naanị site na ọkwa nke fructosamine, yana ezigbo oke - ihe dịka 90%. N'agbanyeghi nke a, ihe omumu a bu ihe zuru ebe nile, a na - eji ya dika ihe na - ejikọta ya na glucose na haemoglobin glycated.

Onye na-arịa ọrịa shuga na-eji glucometer na-arịa ọrịa ya kwa ụbọchị. Ọ bụrụ na i jiri ezi uche nyochaa ihe nchoputa a, enwere ike tụọ nkwụghachi ụgwọ ọrịa shuga n'ụzọ ziri ezi. N'okwu a, ọ dịghị mkpa nyocha maka fructosamine. Ọtụtụ mgbe, ndị dọkịta na-eji ya n’oge nhọrọ nke usoro ọgwụgwọ ọrịa shuga: depụta ọgwụ ole a na-agbakọ, ọgwụ kasịnụ nke carbohydrates dị ukwuu, na mgbe izu abụọ gasịrị, a na-eji fructosamine ikpe ikpe ịdị irè nke ọgwụgwọ.

Ihe ngosi

A na-ahọrọ nyocha nke Fructosamine n'ọnọdụ ndị a:

1. Inyocha izi ezi nke nhọpụta ọgwụgwọ izu abụọ ka mmalite ya.
2. Ọ bụrụ na na ndụ onye ọrịa na-arịa ọrịa shuga enwere nnukwu mgbanwe na-erughị izu isii gara aga. Mgbanwe ndị dị otú ahụ gụnyere nri ọhụrụ, ọkwa dị ukwuu nke mmega ahụ ma ọ bụ izu ike a na-amanye mmadụ, ịba ụba nke ọrịa, karịsịa ndị endocrine.
3. N'oge afọ ime, yana ịmịnye glucose na-ebu ọnụ. Ọ bụ ọbara ọbara haemoglobin n'oge a ekpebighị, ebe ọ bụ na ọnọdụ homonụ nke nwanyị, ya na glucose ọbara na-agbanwekarị. Mgbe ị na-amụ nwa, a na-eji nyocha nke mkpụrụ fructosamine eme ihe kama na haemoglobin glycated.
4. N'ime ụmụ amụrụ ọhụrụ na nsogbu echere na metabolism metabolism. N'ihi ọnụnọ haemoglobin nke nwa ebu n'afọ, n'ọmụmụ banyere fructosamine ka bụ naanị ụzọ a pụrụ ịdabere na ya iji chọpụta glycemia n'ozuzu.
5. N'ọnọdụ ebe nnwale nke ọbara hemoglobin nwere ike ịbụ nke a na-apụghị ịdabere na ya n'ihi enweghị haemoglobin: anaemia; ọrịa ọbara; ọbara ọgbụgba na-adịghị ala ala n'ihi ọbara ọgbụgba, ọnya afọ, nsọ nwanyị dị arọ; ọbara ọgbụgba n'ime ọnwa atọ gara aga; ọrịa hemolytic; ọbara mgbochi ọbara ọbara.
6. Na nkwadebe maka usoro ịwa ahụ, iji chọpụta ịdị njikere nke onye ọrịa nwere ọrịa mellitus nye ha.
7. Ọ bụrụ na enyo enyo nke etolite homonụ na-ebute n’oge na-adịbeghị anya nke na-emetụta shuga ọbara.

Otu esi agafe nyocha

Uru doro anya nke nyocha maka fructosamine bụ ntụkwasị obi dị elu. Onweghi iwu choro maka nkwadebe, nihi na ntinye ihe nlebara obara, nri, mmega ahu na ahuta ubochi abiaghi ihe ozo.

N’agbanyeghi nke a, ulo oru nyocha gwara ndi okenye ka ha guzoro oge 4-8 n’enweghi nri. Maka ụmụ aka, oge ibu ọnụ kwesịrị ịbụ nkeji iri anọ, maka ụmụaka na-erubeghị afọ ise - awa 2.5. Ọ bụrụ na ọ na-esiri onye na-arịa ọrịa shuga ike ịnagide ụdị oge a, ọ ga-ezuru ịhapụ iri nri abụba. Osisi, abụba anụmanụ, ude mmanụ achịcha, chiiz na-abawanye mkpokọta lipids n'ime ọbara, nke nwere ike ibute nsonaazụ a na-apụghị ịtụkwasị obi.

N'ụlọ, ugbu a agaghị ekwe omume ịtụle, ebe ọ bụ na ahapụla mwepụta nke ngwa ule n'ihi nnukwu nzere ntụle dị elu. N'ime ndị ọrịa a na-ehi ụra, ndị ọrụ nyocha ụlọ nwere ike iburu biomatorial ma nyefee ya maka nyocha.

Mbelata

A na-egosipụta nsonaazụ nyocha a na micromoles ma ọ bụ millimoles kwa lita nke ọbara.

Iwu a nabatara maka fructosamine bụ otu ihe n’ebe ụmụ nwoke, ụmụ nwanyị na ndị ntorobịa nke nwoke na nwanyị nọ afọ iri na anọ. N'ọtụtụ ụlọ nyocha, ya na 205-285 mmol / L ma ọ bụ 2.05-2.85 mmol / L. Maka ụmụaka gbara afọ 14, ntakịrị obere: 195-271 μmol / L.

N'ihi eziokwu ahụ bụ na ụlọ ọrụ nyocha nwere ike iji usoro dị iche iche maka ikpebi fructosamine na calibrators sitere na ndị nrụpụta dị iche iche, ụkpụrụ ntinye maka nyocha a nwere ike ịdị iche na obere. Ihe omuma banyere uzo nke anabatara dika ihe di omimi n’ime ulo oru a, di na mpempe ihe o bula enyere onye ahia ya.

Nyochaa onyonyo nke nlekọta shuga:

Nnyocha achọpụtala na nkezi ogo fructosamine (F) maka ọnwa 3 nwere ike gbakọọ pasent nke hemoglobin glycated (HG) na onye ọrịa. Usoro ahụ nwere ike ịnọchite anya mmekọrịta ahụ: GG = 0.017xF + 1.61, ebe a na-egosipụta GG na%, Ф - na micromol / l. Nke ozo: F = (GG-1.61) x58.82.

Enwerekwa mgbakwunye ọkwa nke fructosamine na nkezi shuga ọbara na izu abụọ gara aga:

Ya mere, nyocha a na-enwe ike inye nyocha zuru oke banyere ọnọdụ metabolic nke onye ọrịa, ogo ọgwụgwọ ya.

Isi ihe kpatara fructosamine na-ebili bụ ọrịa mellitus na ọrịa shuga. Dabere na nkwenye nke ụlọ ọgwụ, ọ gaghị ekwe omume ime nchọpụta nchọpụta a dabere na otu nyocha. Ọ dị mkpa ịme nyocha ọzọ ma wezuga ihe ndị ọzọ nwere ike ịbawanye ụba nke fructosamine:

• ụkọ homonụ nke akpa umeji;
• ọdịda odida;
• mmụba ogologo oge na ọkwa immunoglobulin A n'ihi ọrịa, ọnya nke anụ ahụ; ọrịa autoimmune, ọrịa cystic fibrosis, mmebi imeju, ị alcoụbiga mmanya ókè;

Enwere ike belata Fructosamine maka ebumnuche ndị a:

• oke enweghi protin ọbara, ọkachasị albumin. Ikekwe nke a bụ na nri protein dị ala na nri, ụfọdụ ọrịa imeju, na -eche nri mgbaze na-edozi ahụ na usoro nri, yana nephropathy na-arịa ọrịa proteinuria. Obere protein na-emetụta (ma ọ bụrụ na ọkwa albumin dị> 30 g / l) anaghị emetụta nsonaazụ nyocha ahụ;
• hyperthyroidism;
• ogologo oge ị ofụ vitamin C na B

Nchịkọta ọnụahịa

Na ọrịa shuga mellitus, a na-enye nduzi maka nyocha nke dọkịta na-aga - dọkịta ezinụlọ, onye na-agwọ ọrịa ma ọ bụ endocrinologist. Na nke a, ọmụmụ a bụ n'efu. N'ime ụlọ nyocha azụmahịa, ọnụahịa nyocha maka fructosamine dị ntakịrị karịa ọnụego glucose na-ebu ọnụ ma ọ fọrọ nke nta ka ọ bụrụ ugboro abụọ karịa mkpebi nke gemocated glucose. Na mpaghara dị iche iche, ọ dị iche na 250 ruo 400 rubles.